{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T16:45:36Z","timestamp":1791823536354,"version":"4.3.4"},"reference-count":73,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,8,19]],"date-time":"2025-08-19T00:00:00Z","timestamp":1755561600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biotechnology Reports"],"published-print":{"date-parts":[[2025,12]]},"DOI":"10.1016\/j.btre.2025.e00921","type":"journal-article","created":{"date-parts":[[2025,8,20]],"date-time":"2025-08-20T13:23:18Z","timestamp":1755696198000},"page":"e00921","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Investigating a new Dillenia ovata endophytic bacteria to produce antioxidants and anti-diabetes activity in vitro and in vivo"],"prefix":"10.1016","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9068-8798","authenticated-orcid":false,"given":"Linh Chi","family":"Tran","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-4080-5140","authenticated-orcid":false,"given":"Chong Kim Thien","family":"Duc","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2132-113X","authenticated-orcid":false,"given":"Tuan Trong","family":"Nguyen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8693-3367","authenticated-orcid":false,"given":"Duy Toan","family":"Pham","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9153-8794","authenticated-orcid":false,"given":"Danh Thai","family":"Luu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0942-7081","authenticated-orcid":false,"given":"Trang Thi Xuan","family":"Dai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.btre.2025.e00921_bib0001","doi-asserted-by":"crossref","first-page":"7644","DOI":"10.3390\/ijms22147644","article-title":"Diabetes mellitus and its metabolic complications: the role of adipose tissues","volume":"22","author":"Dilworth","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.btre.2025.e00921_bib0002","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.freeradbiomed.2022.03.019","article-title":"Oxidative stress in the pathophysiology of type 2 diabetes and related complications: current therapeutics strategies and future perspectives","volume":"184","author":"Bhatti","year":"2022","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.btre.2025.e00921_bib0003","first-page":"1","article-title":"Diabetic vascular diseases: molecular mechanisms and therapeutic strategies","volume":"8","author":"Li","year":"2023","journal-title":"Sig. Transduct. Target. Ther."},{"key":"10.1016\/j.btre.2025.e00921_bib0004","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1007\/s13205-018-1528-0","article-title":"Role of medicinal plants in the management of diabetes mellitus: a review","volume":"9","author":"Jacob","year":"2019","journal-title":"3 Biotech."},{"key":"10.1016\/j.btre.2025.e00921_bib0005","doi-asserted-by":"crossref","DOI":"10.1016\/j.jaim.2022.100675","article-title":"Aloe vera in diabetic dyslipidemia: improving blood glucose and lipoprotein levels in pre-clinical and clinical studies","volume":"13","author":"Deora","year":"2022","journal-title":"J. Ayurveda Integr. Med."},{"key":"10.1016\/j.btre.2025.e00921_bib0006","article-title":"Phytochemical analysis and antioxidant property of selected medicinal plants native to Cambodia","volume":"1","author":"Samell","year":"2018","journal-title":"Drug Des. Intell. Prop. Int. J."},{"key":"10.1016\/j.btre.2025.e00921_bib0007","doi-asserted-by":"crossref","first-page":"5567","DOI":"10.1007\/s11164-023-05126-z","article-title":"Phytochemical profiles and novel biofunctions of Dillenia ovata Wall. ex Hook.f. et Thomson: a Vietnamese indigenous medicinal plant","volume":"49","author":"Doan","year":"2023","journal-title":"Res. Chem. Intermed."},{"key":"10.1016\/j.btre.2025.e00921_bib0008","doi-asserted-by":"crossref","first-page":"453","DOI":"10.3390\/microorganisms11020453","article-title":"Sustainable applications of endophytic bacteria and their physiological\/biochemical roles on medicinal and herbal plants: review","volume":"11","author":"Tshikhudo","year":"2023","journal-title":"Microorganisms."},{"key":"10.1016\/j.btre.2025.e00921_bib0009","doi-asserted-by":"crossref","first-page":"1538","DOI":"10.3389\/fmicb.2016.01538","article-title":"Endophytes: a treasure house of bioactive compounds of medicinal importance","volume":"7","author":"Gouda","year":"2016","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.btre.2025.e00921_bib0010","doi-asserted-by":"crossref","first-page":"463","DOI":"10.3389\/fmicb.2019.00463","article-title":"Bioactive products from plant-endophytic gram-positive bacteria","volume":"10","author":"Ek-Ramos","year":"2019","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.btre.2025.e00921_bib0011","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2021.633488","article-title":"Endophytic bacteria from the roots of the medicinal plant Alkanna tinctoria Tausch (Boraginaceae): exploration of plant growth promoting properties and potential role in the production of plant secondary metabolites","volume":"12","author":"Rat","year":"2021","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.btre.2025.e00921_bib0012","article-title":"Beneficial relationships between endophytic bacteria and medicinal plants","volume":"12","author":"Wu","year":"2021","journal-title":"Front. Plant Sci."},{"key":"10.1016\/j.btre.2025.e00921_bib0013","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1590\/S1517-838246420140024","article-title":"Screening and characterization of endophytic Bacillus and Paenibacillus strains from medicinal plant Lonicera japonica for use as potential plant growth promoters","volume":"46","author":"Zhao","year":"2015","journal-title":"Braz. J. Microbiol."},{"key":"10.1016\/j.btre.2025.e00921_bib0014","doi-asserted-by":"crossref","first-page":"1095","DOI":"10.1007\/s11738-014-1484-1","article-title":"Effect and mechanism of endophytic bacteria on growth and secondary metabolite synthesis in Salvia miltiorrhiza hairy roots","volume":"36","author":"Yan","year":"2014","journal-title":"Acta Physiol. Plant."},{"key":"10.1016\/j.btre.2025.e00921_bib0015","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1080\/14786419.2013.863198","article-title":"A new cyclic tetrapeptide from an endophytic Streptomyces sp. YIM67005","volume":"28","author":"Zhou","year":"2014","journal-title":"Nat. Prod. Res."},{"key":"10.1016\/j.btre.2025.e00921_bib0016","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2017.01642","article-title":"Antibacterial activity of endophytic actinomycetes isolated from the medicinal plant Vochysia divergens (Pantanal, Brazil)","volume":"8","author":"Gos","year":"2017","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.btre.2025.e00921_bib0017","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1007\/s13205-017-0735-4","article-title":"Endophytic Nocardiopsis sp. from Zingiber officinale with both antiphytopathogenic mechanisms and antibiofilm activity against clinical isolates","volume":"7","author":"Sabu","year":"2017","journal-title":"3. Biotech."},{"key":"10.1016\/j.btre.2025.e00921_bib0018","doi-asserted-by":"crossref","first-page":"924","DOI":"10.3389\/fmicb.2018.00924","article-title":"Evaluation of the antimicrobial activity of endophytic bacterial populations from Chinese traditional medicinal plant licorice and characterization of the bioactive secondary metabolites produced by Bacillus atrophaeus against Verticillium dahliae","volume":"9","author":"Mohamad","year":"2018","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.btre.2025.e00921_bib0019","doi-asserted-by":"crossref","first-page":"47","DOI":"10.3389\/fpls.2020.00047","article-title":"Beneficial endophytic bacterial populations associated with medicinal plant Thymus vulgaris alleviate salt stress and confer resistance to Fusarium oxysporum","volume":"11","author":"Abdelshafy Mohamad","year":"2020","journal-title":"Front. Plant Sci."},{"key":"10.1016\/j.btre.2025.e00921_bib0020","doi-asserted-by":"crossref","first-page":"008","DOI":"10.7324\/JAPS.2014.40402","article-title":"Antibacterial activity of new flavonoids from Streptomyces sp. BT01; an endophyte in Boesenbergia rotunda (L.) Mansf","volume":"4","author":"Taechowisan","year":"2014","journal-title":"J. App. Pharm. Sci."},{"key":"10.1016\/j.btre.2025.e00921_bib0021","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1002\/cbdv.201500225","article-title":"Endophytic actinobacteria from the Brazilian medicinal plant Lychnophora ericoides Mart. and the biological potential of their secondary metabolites","volume":"13","author":"Conti","year":"2016","journal-title":"Chem. Biodivers."},{"key":"10.1016\/j.btre.2025.e00921_bib0022","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1007\/s13596-019-00410-z","article-title":"Exploring the bioactive compounds from endophytic bacteria of a medicinal plant: Ephedra foliata (Ephedrales: Ephedraceae)","volume":"20","author":"Ghiasvand","year":"2020","journal-title":"Adv. Tradit. Med."},{"key":"10.1016\/j.btre.2025.e00921_bib0023","doi-asserted-by":"crossref","first-page":"139","DOI":"10.5455\/spatula.20140826011114","article-title":"Antidiabetic potential of endophytic bacterial fraction of Murraya Koenigii (L.) Spreng.in Rats","volume":"4","author":"Habbu","year":"2014","journal-title":"Spatula DD"},{"key":"10.1016\/j.btre.2025.e00921_bib0024","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1111\/lam.12209","article-title":"Streptomycete endophytes from anti-diabetic medicinal plants of the Western Ghats inhibit alpha-amylase and promote glucose uptake","volume":"58","author":"Akshatha","year":"2014","journal-title":"Lett. Appl. Microbiol."},{"key":"10.1016\/j.btre.2025.e00921_bib0025","doi-asserted-by":"crossref","DOI":"10.13057\/biodiv\/d240330","article-title":"Isolation and characterization of endophytic bacteria from sterile leaf of Acrostichum aureum from Bengkalis Island (Riau, Indonesia) and its potency for antidiabetic","volume":"24","author":"Linda","year":"2023","journal-title":"Biodiversitas J. Biol. Diversity"},{"key":"10.1016\/j.btre.2025.e00921_bib0026","doi-asserted-by":"crossref","unstructured":"V.L. Singleton, R. Orthofer, R.M. Lamuela-Ravent\u00f3s, [14]Analysis of total phenols and other oxidation substrates and antioxidants by means of folin-ciocalteu reagent, 299 (1999) 152\u2013178. https:\/\/doi.org\/10.1016\/S0076-6879(99)99017-1.","DOI":"10.1016\/S0076-6879(99)99017-1"},{"key":"10.1016\/j.btre.2025.e00921_bib0027","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1016\/j.sajb.2024.01.052","article-title":"Isolating Miliusa velutina endophytic bacteria to generate antioxidants and optimizing culture conditions for antioxidant production","volume":"166","author":"Dai","year":"2024","journal-title":"South Afr. J. Bot."},{"key":"10.1016\/j.btre.2025.e00921_bib0028","first-page":"172","article-title":"Cross amplification of 16S rRNA bacterial primer 27F\/1492R on horticultural crop chloroplast genome","volume":"7","author":"Santosa","year":"2024","journal-title":"Agric. Sci."},{"key":"10.1016\/j.btre.2025.e00921_bib0029","doi-asserted-by":"crossref","first-page":"555","DOI":"10.3390\/horticulturae7120555","article-title":"Phytochemicals, antioxidant and antidiabetic activities of extracts from Miliusa velutina flowers","volume":"7","author":"Anh","year":"2021","journal-title":"Horticulturae"},{"key":"10.1016\/j.btre.2025.e00921_bib0030","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1186\/s40816-019-0137-8","article-title":"Evaluation of anti-inflammatory activity of Justicia secunda Vahl leaf extract using in vitro and in vivo inflammation models","volume":"5","author":"Anyasor","year":"2019","journal-title":"Clin. Phytosci."},{"key":"10.1016\/j.btre.2025.e00921_bib0031","article-title":"Protective effect of bergapten against human erythrocyte hemolysis and protein denaturation in vitro","volume":"2021","author":"Aidoo","year":"2021","journal-title":"Int. J. Inflam."},{"key":"10.1016\/j.btre.2025.e00921_bib0032","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.sajb.2020.09.039","article-title":"Inhibitory activities of medicinal mushrooms on \u03b1-amylase and \u03b1-glucosidase-enzymes related to type 2 diabetes","volume":"137","author":"Deveci","year":"2021","journal-title":"South Afr. J. Bot."},{"key":"10.1016\/j.btre.2025.e00921_bib0033","series-title":"National Research Council (US) Committee for the Update of the Guide for theCare and Use of Laboratory Animals, Guide for the Care and Use of Laboratory Animals","year":"2011"},{"key":"10.1016\/j.btre.2025.e00921_bib0034","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1186\/s12906-016-1530-1","article-title":"Hypoglycemic and pancreatic protective effects of Portulaca oleracea extract in alloxan induced diabetic rats","volume":"17","author":"Ramadan","year":"2017","journal-title":"BMC Complementary Altern. Med."},{"key":"10.1016\/j.btre.2025.e00921_bib0035","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1093\/clinchem\/18.6.499","article-title":"Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge","volume":"18","author":"Friedewald","year":"1972","journal-title":"Clin. Chem."},{"key":"10.1016\/j.btre.2025.e00921_bib0036","doi-asserted-by":"crossref","first-page":"156","DOI":"10.3390\/antiox8060156","article-title":"Effect of propolis on diet-induced hyperlipidemia and atherogenic indices in mice","volume":"8","author":"Or\u0161oli\u0107","year":"2019","journal-title":"Antioxidants"},{"key":"10.1016\/j.btre.2025.e00921_bib0037","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/0003-2697(79)90738-3","article-title":"Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction","volume":"95","author":"Ohkawa","year":"1979","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.btre.2025.e00921_bib0038","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/0304-4165(79)90289-7","article-title":"Levels of glutathione, glutathione reductase and glutathione S-transferase activities in rat lung and liver","volume":"582","author":"Moron","year":"1979","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.btre.2025.e00921_bib0039","doi-asserted-by":"crossref","DOI":"10.1155\/2021\/6938433","article-title":"Histopathological profiles of rats (Rattus norvegicus) induced with streptozotocin and treated with aqueous root extracts of Ruellia tuberosa L","volume":"2021","author":"Safitri","year":"2021","journal-title":"Vet. Med. Int."},{"key":"10.1016\/j.btre.2025.e00921_bib0040","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1186\/s12941-017-0228-7","article-title":"An assessment on the role of endophytic microbes in the therapeutic potential of Fagonia indica","volume":"16","author":"Rahman","year":"2017","journal-title":"Ann. Clin. Microbiol. Antimicrob."},{"key":"10.1016\/j.btre.2025.e00921_bib0041","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2021.633488","article-title":"Endophytic bacteria from the roots of the medicinal plant Alkanna tinctoria Tausch (Boraginaceae): exploration of plant growth promoting properties and potential role in the production of plant secondary metabolites","volume":"12","author":"Rat","year":"2021","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.btre.2025.e00921_bib0042","article-title":"Caffeic acid phenolipids in the protection of cell membranes from oxidative injuries. Interaction with the membrane phospholipid bilayer","volume":"1863","author":"Lopes","year":"2021","journal-title":"Biochim. Biophys. Acta (BBA) Biomembranes"},{"key":"10.1016\/j.btre.2025.e00921_bib0043","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/j.fshw.2020.04.003","article-title":"Antioxidant and \u03b1-glucosidase inhibitiory activity of Cercis chinensis flowers","volume":"9","author":"Zhang","year":"2020","journal-title":"Food Sci. Hum. Wellness"},{"key":"10.1016\/j.btre.2025.e00921_bib0044","doi-asserted-by":"crossref","first-page":"467","DOI":"10.3390\/molecules30030467","article-title":"Antioxidant and anti-inflammatory effects of vanillic acid in human plasma, human neutrophils, and non-cellular models in vitro","volume":"30","author":"Magiera","year":"2025","journal-title":"Molecules."},{"key":"10.1016\/j.btre.2025.e00921_bib0045","doi-asserted-by":"crossref","first-page":"545","DOI":"10.3390\/antiox10040545","article-title":"Composition and antioxidant activity of phenolic compounds in fruit of the genus Rosa L","volume":"10","author":"Liaudanskas","year":"2021","journal-title":"Antioxidants"},{"key":"10.1016\/j.btre.2025.e00921_bib0046","doi-asserted-by":"crossref","first-page":"1076","DOI":"10.3390\/biomedicines10051076","article-title":"potential and therapeutic roles of Diosmin in human diseases","volume":"10","author":"Huwait","year":"2022","journal-title":"Biomedicines."},{"key":"10.1016\/j.btre.2025.e00921_bib0047","doi-asserted-by":"crossref","DOI":"10.3389\/fnut.2023.1192131","article-title":"Flavonoids improve type 2 diabetes mellitus and its complications: a review","volume":"10","author":"Yi","year":"2023","journal-title":"Front. Nutr."},{"key":"10.1016\/j.btre.2025.e00921_bib0048","doi-asserted-by":"crossref","first-page":"430","DOI":"10.3390\/biom9090430","article-title":"Flavonoids and their anti-diabetic effects: cellular mechanisms and effects to improve blood sugar levels","volume":"9","author":"AL-Ishaq","year":"2019","journal-title":"Biomolecules."},{"key":"10.1016\/j.btre.2025.e00921_bib0049","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/j.sjbs.2021.08.099","article-title":"Therapeutic prospects of endophytic Bacillus species from Berberis lycium against oxidative stress and microbial pathogens","volume":"29","author":"Nisa","year":"2022","journal-title":"Saudi J. Biol. Sci."},{"key":"10.1016\/j.btre.2025.e00921_bib0050","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2021.114517","article-title":"Anti-inflammatory activity of endophytic bacterial isolates from Emilia sonchifolia (Linn.) DC","volume":"281","author":"Urumbil","year":"2021","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.btre.2025.e00921_bib0051","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1016\/j.jff.2014.12.049","article-title":"Anti-diabetic activity in type 2 diabetic mice and \u03b1-glucosidase inhibitory, antioxidant and anti-inflammatory potential of chemically profiled pear peel and pulp extracts (Pyrus spp.)","volume":"13","author":"Wang","year":"2015","journal-title":"J. Funct. Foods"},{"key":"10.1016\/j.btre.2025.e00921_bib0052","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1016\/j.tifs.2006.04.004","article-title":"Sources of natural phenolic antioxidants","volume":"17","author":"Dimitrios","year":"2006","journal-title":"Trends Food Sci. Technol."},{"key":"10.1016\/j.btre.2025.e00921_bib0053","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1016\/j.foodchem.2008.08.025","article-title":"Antioxidant capacity and the relationship with polyphenol and Vitamin C in Actinidia fruits","volume":"113","author":"Du","year":"2009","journal-title":"Food Chem."},{"key":"10.1016\/j.btre.2025.e00921_bib0054","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1016\/j.jep.2008.11.002","article-title":"Anti-inflammatory activity of flavonoids from Cayaponia tayuya roots","volume":"121","author":"Aquila","year":"2009","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.btre.2025.e00921_bib0055","doi-asserted-by":"crossref","first-page":"2236","DOI":"10.1248\/bpb.29.2236","article-title":"Evaluation of the anti-inflammatory, analgesic and antipyretic activities of the natural polyphenol chlorogenic acid","volume":"29","author":"dos Santos","year":"2006","journal-title":"Biol. Pharm. Bull."},{"key":"10.1016\/j.btre.2025.e00921_bib0056","article-title":"Optimization of the cultivation conditions of Bacillus licheniformis BCLLNF-01 for cellulase production","volume":"29","author":"da Silva","year":"2021","journal-title":"Biotechnol. Rep."},{"key":"10.1016\/j.btre.2025.e00921_bib0057","doi-asserted-by":"crossref","first-page":"651","DOI":"10.3390\/microorganisms12040651","article-title":"Optimization of culture conditions and batch process control for the augmented production of bacteriocin by Bacillus species","volume":"12","author":"Elazzazy","year":"2024","journal-title":"Microorganisms"},{"key":"10.1016\/j.btre.2025.e00921_bib0058","doi-asserted-by":"crossref","first-page":"1058","DOI":"10.1161\/CIRCRESAHA.110.223545","article-title":"Oxidative stress and diabetic complications","volume":"107","author":"Giacco","year":"2010","journal-title":"Circ. Res."},{"key":"10.1016\/j.btre.2025.e00921_bib0059","doi-asserted-by":"crossref","first-page":"281","DOI":"10.3746\/pnf.2014.19.4.281","article-title":"Anti-diabetic and anti-inflammatory effects of green and red kohlrabi cultivars (Brassica oleracea var. gongylodes)","volume":"19","author":"Jung","year":"2014","journal-title":"Prev. Nutr. Food Sci."},{"key":"10.1016\/j.btre.2025.e00921_bib0060","first-page":"57","article-title":"The formulation and test of antioxidant activity from serum gel of the extract chrysanthemum flower (Chrysanthemum Indicum L.)","volume":"1","author":"Taurhesia","year":"2024","journal-title":"J. Nat. Prod. Degenerative Dis."},{"key":"10.1016\/j.btre.2025.e00921_bib0061","doi-asserted-by":"crossref","first-page":"21","DOI":"10.32493\/jitk.v7i1.25106","article-title":"Determination of IC50 root extracts of Bajakah Tampala (Spatholobus littoralis Hassk) and Kalalawit (Uncaria gambir Roxb) using DPPH method","volume":"7","author":"Merdita","year":"2023","journal-title":"J. Ilmiah Teknik Kimia"},{"key":"10.1016\/j.btre.2025.e00921_bib0062","doi-asserted-by":"crossref","DOI":"10.1155\/2020\/4237205","article-title":"Antioxidant and nephroprotective effects of okra pods extract (Abelmoschus esculentus L.) against lead acetate-induced toxicity in mice","volume":"2020","author":"Wahyuningsih","year":"2020","journal-title":"Scientifica"},{"key":"10.1016\/j.btre.2025.e00921_bib0063","article-title":"In vitro anti-inflammatory activity of different parts of Pedalium murex (L.)","author":"Sangeetha","year":"2016","journal-title":"Int. J. Herb. Med."},{"key":"10.1016\/j.btre.2025.e00921_bib0064","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.3390\/biomedicines13051053","article-title":"Lysosomal stress in cardiovascular diseases: therapeutic potential of cardiovascular drugs and future directions","volume":"13","author":"Otoda","year":"2025","journal-title":"Biomedicines."},{"key":"10.1016\/j.btre.2025.e00921_bib0065","doi-asserted-by":"crossref","first-page":"1692","DOI":"10.3390\/life12111692","article-title":"Dietary polyphenols as natural inhibitors of \u03b1-amylase and \u03b1-glucosidase","volume":"12","author":"\u0106orkovi\u0107","year":"2022","journal-title":"Life"},{"key":"10.1016\/j.btre.2025.e00921_bib0066","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodchem.2021.131231","article-title":"Understanding phenolic acids inhibition of \u03b1-amylase and \u03b1-glucosidase and influence of reaction conditions","volume":"372","author":"Aleixandre","year":"2022","journal-title":"Food Chem."},{"key":"10.1016\/j.btre.2025.e00921_bib0067","doi-asserted-by":"crossref","first-page":"537","DOI":"10.33549\/physiolres.930111","article-title":"The mechanism of alloxan and streptozotocin action in B cells of the rat pancreas","volume":"50","author":"Szkudelski","year":"2001","journal-title":"Physiol. Res."},{"key":"10.1016\/j.btre.2025.e00921_bib0068","doi-asserted-by":"crossref","first-page":"6651","DOI":"10.3390\/cimb45080420","article-title":"Oxidative stress in type 2 diabetes: impacts from pathogenesis to lifestyle modifications","volume":"45","author":"Caturano","year":"2023","journal-title":"Curr. Issues. Mol. Biol."},{"key":"10.1016\/j.btre.2025.e00921_bib0069","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1007\/s11886-019-1175-z","article-title":"Optimizing dyslipidemia management for the prevention of cardiovascular disease: a focus on risk assessment and therapeutic options","volume":"21","author":"Berman","year":"2019","journal-title":"Curr. Cardiol. Rep."},{"key":"10.1016\/j.btre.2025.e00921_bib0070","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1016\/S0140-6736(14)61177-6","article-title":"Triglycerides and cardiovascular disease","volume":"384","author":"Nordestgaard","year":"2014","journal-title":"Lancet"},{"key":"10.1016\/j.btre.2025.e00921_bib0071","doi-asserted-by":"crossref","first-page":"1509","DOI":"10.3390\/ijms22041509","article-title":"The role of oxidative stress in pancreatic \u03b2 cell dysfunction in diabetes","volume":"22","author":"Eguchi","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.btre.2025.e00921_bib0072","doi-asserted-by":"crossref","first-page":"e132","DOI":"10.18295\/squmj.2016.16.02.002","article-title":"Mechanisms of diabetes-induced liver damage: the role of oxidative stress and inflammation","volume":"16","author":"Mohamed","year":"2016","journal-title":"Sultan. Qaboos. Univ. Med. J."},{"key":"10.1016\/j.btre.2025.e00921_bib0073","article-title":"Diabetic kidney disease","volume":"1","author":"Thomas","year":"2015","journal-title":"Nat. Rev. Dis. Primers."}],"container-title":["Biotechnology Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2215017X25000487?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2215017X25000487?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T15:55:03Z","timestamp":1791820503000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2215017X25000487"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12]]},"references-count":73,"alternative-id":["S2215017X25000487"],"URL":"https:\/\/doi.org\/10.1016\/j.btre.2025.e00921","relation":{},"ISSN":["2215-017X"],"issn-type":[{"value":"2215-017X","type":"print"}],"subject":[],"published":{"date-parts":[[2025,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Investigating a new Dillenia ovata endophytic bacteria to produce antioxidants and anti-diabetes activity in vitro and in vivo","name":"articletitle","label":"Article Title"},{"value":"Biotechnology Reports","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.btre.2025.e00921","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"e00921"}}