{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,3,5]],"date-time":"2025-03-05T05:47:27Z","timestamp":1741153647588,"version":"3.38.0"},"reference-count":49,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Bulletin du Cancer"],"published-print":{"date-parts":[[2025,3]]},"DOI":"10.1016\/j.bulcan.2024.07.005","type":"journal-article","created":{"date-parts":[[2025,3,4]],"date-time":"2025-03-04T20:48:09Z","timestamp":1741121289000},"page":"241-250","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Chirurgie prophylactique et oncog\u00e9n\u00e9tique\u00a0: quel impact de l\u2019intelligence artificielle\u00a0?"],"prefix":"10.1016","volume":"112","author":[{"given":"Olivier","family":"Caron","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.bulcan.2024.07.005_bib0005","series-title":"Collection recommandations et r\u00e9f\u00e9rentiels","article-title":"Chirurgie prophylactique des cancers avec pr\u00e9disposition g\u00e9n\u00e9tique [Internet]","year":"2009"},{"issue":"1","key":"10.1016\/j.bulcan.2024.07.005_bib0010","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.bjps.2021.06.012","article-title":"Patient reported outcome measures in a cohort of patients at high risk of breast cancer treated by bilateral risk reducing mastectomy and breast reconstruction","volume":"75","author":"Gandhi","year":"2022","journal-title":"J Plast Reconstr Aesthet Surg"},{"issue":"15","key":"10.1016\/j.bulcan.2024.07.005_bib0015","doi-asserted-by":"crossref","first-page":"3971","DOI":"10.1158\/1078-0432.CCR-15-1465","article-title":"Effectiveness of prophylactic surgeries in BRCA1\u00a0or BRCA2\u00a0mutation carriers: a meta-analysis and systematic review","volume":"22","author":"Li","year":"2016","journal-title":"Clin Cancer Res"},{"issue":"4","key":"10.1016\/j.bulcan.2024.07.005_bib0020","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1001\/jamaoncol.2023.6937","article-title":"Bilateral oophorectomy and all-cause mortality in women with BRCA1 and BRCA2 sequence variations","volume":"10","author":"Kotsopoulos","year":"2024","journal-title":"JAMA Oncol [Internet]"},{"issue":"11","key":"10.1016\/j.bulcan.2024.07.005_bib0025","doi-asserted-by":"crossref","first-page":"1050","DOI":"10.1001\/jamasurg.2020.3356","article-title":"Indications for total gastrectomy in CDH1\u00a0mutation carriers and outcomes of risk-reducing minimally invasive and open gastrectomies","volume":"155","author":"Vos","year":"2020","journal-title":"JAMA Surg"},{"key":"10.1016\/j.bulcan.2024.07.005_bib0030","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1016\/j.breast.2019.01.013","article-title":"Body image problems in women with and without breast cancer 6\u201320\u00a0years after bilateral risk-reducing surgery\u00a0\u2013\u00a0a prospective follow-up study","volume":"44","author":"Bai","year":"2019","journal-title":"Breast"},{"issue":"9","key":"10.1016\/j.bulcan.2024.07.005_bib0035","doi-asserted-by":"crossref","first-page":"2502","DOI":"10.1245\/s10434-017-5915-2","article-title":"Impact of bilateral prophylactic mastectomy and immediate reconstruction on health-related quality of life in women at high risk for breast carcinoma: results of the mastectomy reconstruction outcomes consortium study","volume":"24","author":"McCarthy","year":"2017","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.bulcan.2024.07.005_bib0040","doi-asserted-by":"crossref","first-page":"e067528","DOI":"10.1136\/bmj-2021-067528","article-title":"Association of bilateral salpingo-oophorectomy with all cause and cause specific mortality: population based cohort study","volume":"375","author":"Cusimano","year":"2021","journal-title":"BMJ"},{"issue":"10","key":"10.1016\/j.bulcan.2024.07.005_bib0045","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1016\/j.bulcan.2018.08.003","article-title":"[The French Genetic and Cancer Consortium guidelines for multigene panel analysis in hereditary breast and ovarian cancer predisposition]","volume":"105","author":"Moretta","year":"2018","journal-title":"Bull Cancer"},{"issue":"12","key":"10.1016\/j.bulcan.2024.07.005_bib0050","doi-asserted-by":"crossref","first-page":"104080","DOI":"10.1016\/j.ejmg.2020.104080","article-title":"National recommendations of the French Genetics and Cancer Group\u00a0\u2013\u00a0unicancer on the modalities of multi-genes panel analyses in hereditary predispositions to tumors of the digestive tract","volume":"63","author":"Dhooge","year":"2020","journal-title":"Eur J Med Genet"},{"issue":"1","key":"10.1016\/j.bulcan.2024.07.005_bib0055","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1038\/s41467-020-20847-0","article-title":"MVP predicts the pathogenicity of missense variants by deep learning","volume":"12","author":"Qi","year":"2021","journal-title":"Nat Commun"},{"key":"10.1016\/j.bulcan.2024.07.005_bib0060","doi-asserted-by":"crossref","first-page":"101472","DOI":"10.1016\/j.gimo.2024.101472","article-title":"O31: the landscape of variant reclassification: learnings from over 2\u00a0million classified variants in over 3.6\u00a0million individuals","volume":"2","author":"Johnson","year":"2024","journal-title":"Genet Med Open"},{"issue":"1","key":"10.1016\/j.bulcan.2024.07.005_bib0065","doi-asserted-by":"crossref","first-page":"6695","DOI":"10.1038\/s41467-023-42453-6","article-title":"Validation of MSIntuit as an AI-based pre-screening tool for MSI detection from colorectal cancer histology slides","volume":"14","author":"Saillard","year":"2023","journal-title":"Nat Commun"},{"issue":"23","key":"10.1016\/j.bulcan.2024.07.005_bib0070","doi-asserted-by":"crossref","first-page":"2402","DOI":"10.1001\/jama.2017.7112","article-title":"Risks of breast, ovarian, and contralateral breast cancer for BRCA1\u00a0and BRCA2\u00a0mutation carriers","volume":"317","author":"Kuchenbaecker","year":"2017","journal-title":"JAMA"},{"issue":"4","key":"10.1016\/j.bulcan.2024.07.005_bib0075","doi-asserted-by":"crossref","first-page":"e203959","DOI":"10.1001\/jamanetworkopen.2020.3959","article-title":"Association of rare pathogenic DNA variants for familial hypercholesterolemia, hereditary breast and ovarian cancer syndrome, and Lynch syndrome with disease risk in adults according to family history","volume":"3","author":"Patel","year":"2020","journal-title":"JAMA Netw Open"},{"issue":"4","key":"10.1016\/j.bulcan.2024.07.005_bib0080","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1001\/jama.2021.23686","article-title":"Population-based penetrance of deleterious clinical variants","volume":"327","author":"Forrest","year":"2022","journal-title":"JAMA"},{"issue":"1","key":"10.1016\/j.bulcan.2024.07.005_bib0085","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1136\/jmedgenet-2017-104560","article-title":"The BRCA1\u00a0c. 5096G>A p.Arg1699Gln (R1699Q) intermediate risk variant: breast and ovarian cancer risk estimation and recommendations for clinical management from the ENIGMA consortium","volume":"55","author":"Moghadasi","year":"2018","journal-title":"J Med Genet"},{"issue":"6","key":"10.1016\/j.bulcan.2024.07.005_bib0090","doi-asserted-by":"crossref","first-page":"1348","DOI":"10.1053\/gast.2001.29611","article-title":"Incidence of gastric cancer and breast cancer in CDH1 (E-cadherin) mutation carriers from hereditary diffuse gastric cancer families","volume":"121","author":"Pharoah","year":"2001","journal-title":"Gastroenterology"},{"issue":"9","key":"10.1016\/j.bulcan.2024.07.005_bib0095","doi-asserted-by":"crossref","first-page":"1325","DOI":"10.1001\/jamaoncol.2019.1208","article-title":"Comparison of CDH1\u00a0penetrance estimates in clinically ascertained families vs. families ascertained for multiple gastric cancers","volume":"5","author":"Roberts","year":"2019","journal-title":"JAMA Oncol"},{"issue":"9","key":"10.1016\/j.bulcan.2024.07.005_bib0100","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1001\/jama.2024.10852","article-title":"Germline CDH1 variants and lifetime cancer risk","volume":"332","author":"Ryan","year":"2024","journal-title":"JAMA"},{"key":"10.1016\/j.bulcan.2024.07.005_bib0105","series-title":"Oncog\u00e9n\u00e9tique en 2020\/consultations & laboratoires, suivi en 2019\u00a0et 2020","year":"2022"},{"key":"10.1016\/j.bulcan.2024.07.005_bib0110","series-title":"Les analyses g\u00e9nomiques en France en oncog\u00e9n\u00e9tique constitutionnelle\u00a0: bilan de 4\u00a0ans d\u2019exp\u00e9rience dans le cadre du plan France m\u00e9decine g\u00e9nomique 2025","author":"Delhomelle","year":"2024"},{"issue":"1","key":"10.1016\/j.bulcan.2024.07.005_bib0115","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1186\/s13073-021-00965-0","article-title":"Artificial intelligence enables comprehensive genome interpretation and nomination of candidate diagnoses for rare genetic diseases","volume":"13","author":"De La Vega","year":"2021","journal-title":"Genome Med"},{"key":"10.1016\/j.bulcan.2024.07.005_bib0120","unstructured":"MyPebs: international randomized study comparing personalized, risk-stratified to standard breast cancer screening in women aged 40\u201370 [Internet]. Disponible sur\u00a0: https:\/\/clinicaltrials.gov\/study\/NCT03672331."},{"key":"10.1016\/j.bulcan.2024.07.005_bib0125","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1038\/s41523-017-0035-5","article-title":"The WISDOM Study: breaking the deadlock in the breast cancer screening debate","volume":"3","author":"Esserman","year":"2017","journal-title":"NPJ Breast Cancer"},{"issue":"10","key":"10.1016\/j.bulcan.2024.07.005_bib0130","doi-asserted-by":"crossref","first-page":"1653","DOI":"10.1038\/s41436-020-0862-x","article-title":"Polygenic risk scores and breast and epithelial ovarian cancer risks for carriers of BRCA1\u00a0and BRCA2\u00a0pathogenic variants","volume":"22","author":"Barnes","year":"2020","journal-title":"Genet Med"},{"key":"10.1016\/j.bulcan.2024.07.005_bib0135","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.ejca.2022.11.007","article-title":"Association and performance of polygenic risk scores for breast cancer among French women presenting or not a familial predisposition to the disease","volume":"179","author":"Jiao","year":"2023","journal-title":"Eur J Cancer"},{"issue":"1","key":"10.1016\/j.bulcan.2024.07.005_bib0140","doi-asserted-by":"crossref","first-page":"6383","DOI":"10.1038\/s41467-020-19966-5","article-title":"The role of polygenic risk and susceptibility genes in breast cancer over the course of life","volume":"11","author":"Mars","year":"2020","journal-title":"Nat Commun"},{"issue":"8","key":"10.1016\/j.bulcan.2024.07.005_bib0145","doi-asserted-by":"crossref","first-page":"1708","DOI":"10.1038\/s41436-018-0406-9","article-title":"BOADICEA: a comprehensive breast cancer risk prediction model incorporating genetic and nongenetic risk factors","volume":"21","author":"Lee","year":"2019","journal-title":"Genet Med"},{"issue":"1","key":"10.1016\/j.bulcan.2024.07.005_bib0150","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1186\/s13058-021-01399-7","article-title":"Comparative validation of the BOADICEA and Tyrer-Cuzick breast cancer risk models incorporating classical risk factors and polygenic risk in a population-based prospective cohort of women of European ancestry","volume":"23","author":"Pal Choudhury","year":"2021","journal-title":"Breast Cancer Res"},{"issue":"3","key":"10.1016\/j.bulcan.2024.07.005_bib0155","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1158\/1055-9965.EPI-20-1319","article-title":"CanRisk tool\u00a0\u2013\u00a0a web interface for the prediction of breast and ovarian cancer risk and the likelihood of carrying genetic pathogenic variants","volume":"30","author":"Carver","year":"2021","journal-title":"Cancer Epidemiol Biomark Prev"},{"issue":"1","key":"10.1016\/j.bulcan.2024.07.005_bib0160","doi-asserted-by":"crossref","first-page":"11632","DOI":"10.1038\/s41598-024-62513-1","article-title":"Stacked neural network for predicting polygenic risk score","volume":"14","author":"Kim","year":"2024","journal-title":"Sci Rep"},{"issue":"5","key":"10.1016\/j.bulcan.2024.07.005_bib0165","doi-asserted-by":"crossref","first-page":"860","DOI":"10.1038\/s41416-020-0937-0","article-title":"Machine learning-based lifetime breast cancer risk reclassification compared with the BOADICEA model: impact on screening recommendations","volume":"123","author":"Ming","year":"2020","journal-title":"Br J Cancer"},{"issue":"14","key":"10.1016\/j.bulcan.2024.07.005_bib0170","doi-asserted-by":"crossref","first-page":"2536","DOI":"10.1200\/JCO.22.01564","article-title":"Long-term performance of an image-based short-term risk model for breast cancer","volume":"41","author":"Eriksson","year":"2023","journal-title":"J Clin Oncol"},{"issue":"11","key":"10.1016\/j.bulcan.2024.07.005_bib0175","doi-asserted-by":"crossref","first-page":"3479","DOI":"10.3390\/cancers12113479","article-title":"Breast cancer mortality among women with a BRCA1\u00a0or BRCA2\u00a0mutation in a magnetic resonance imaging plus mammography screening program","volume":"12","author":"Warner","year":"2020","journal-title":"Cancers"},{"issue":"4","key":"10.1016\/j.bulcan.2024.07.005_bib0180","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1001\/jamaoncol.2023.6944","article-title":"MRI surveillance and breast cancer mortality in women with BRCA1 and BRCA2 sequence variations","volume":"10","author":"Lubinski","year":"2024","journal-title":"JAMA Oncol [Internet]"},{"key":"10.1016\/j.bulcan.2024.07.005_bib0185","series-title":"Collection recommandations et r\u00e9f\u00e9rentiels","article-title":"Femmes porteuses d\u2019une mutation de BRCA1\u00a0ou BRCA2\/d\u00e9tection pr\u00e9coce du cancer du sein et des annexes et strat\u00e9gies de r\u00e9duction du risque","year":"2017"},{"issue":"7_Supplement","key":"10.1016\/j.bulcan.2024.07.005_bib0190","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1158\/1538-7445.AM2023-773","article-title":"Abstract 773: early detection of ovarian cancer using cell-free DNA fragmentomes","volume":"83","author":"Annapragada","year":"2023","journal-title":"Cancer Res"},{"issue":"403","key":"10.1016\/j.bulcan.2024.07.005_bib0195","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.aan2415","article-title":"Direct detection of early-stage cancers using circulating tumor DNA","volume":"9","author":"Phallen","year":"2017","journal-title":"Sci Transl Med"},{"issue":"7761","key":"10.1016\/j.bulcan.2024.07.005_bib0200","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1038\/s41586-019-1272-6","article-title":"Genome-wide cell-free DNA fragmentation in patients with cancer","volume":"570","author":"Cristiano","year":"2019","journal-title":"Nature"},{"issue":"6378","key":"10.1016\/j.bulcan.2024.07.005_bib0205","doi-asserted-by":"crossref","first-page":"926","DOI":"10.1126\/science.aar3247","article-title":"Detection and localization of surgically resectable cancers with a multi-analyte blood test","volume":"359","author":"Cohen","year":"2018","journal-title":"Science"},{"issue":"6","key":"10.1016\/j.bulcan.2024.07.005_bib0210","doi-asserted-by":"crossref","first-page":"1568","DOI":"10.1053\/j.gastro.2023.07.010","article-title":"AGA clinical practice update on the role of artificial intelligence in colon polyp diagnosis and management: commentary","volume":"165","author":"Samarasena","year":"2023","journal-title":"Gastroenterology"},{"issue":"1","key":"10.1016\/j.bulcan.2024.07.005_bib0215","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1002\/ueg2.12354","article-title":"Real-time use of artificial intelligence (CADEYE) in colorectal cancer surveillance of patients with Lynch syndrome\u00a0\u2013\u00a0a randomized controlled pilot trial (CADLY)","volume":"11","author":"H\u00fcneburg","year":"2023","journal-title":"United European Gastroenterol J"},{"issue":"1","key":"10.1016\/j.bulcan.2024.07.005_bib0220","doi-asserted-by":"crossref","DOI":"10.1177\/03000605231223454","article-title":"Applications of artificial intelligence in gastroscopy: a narrative review","volume":"52","author":"Chen","year":"2024","journal-title":"J Int Med Res"},{"key":"10.1016\/j.bulcan.2024.07.005_bib0225","doi-asserted-by":"crossref","first-page":"e2300123","DOI":"10.1200\/CCI.23.00123","article-title":"Chatbot artificial intelligence for genetic cancer risk assessment and counseling: a systematic review and meta-analysis","volume":"7","author":"Webster","year":"2023","journal-title":"JCO Clin Cancer Inform"},{"issue":"10","key":"10.1016\/j.bulcan.2024.07.005_bib0230","doi-asserted-by":"crossref","first-page":"5990","DOI":"10.1245\/s10434-023-13888-4","article-title":"A randomized trial comparing the effectiveness of pre-test genetic counseling using an artificial intelligence automated chatbot and traditional in-person genetic counseling in women newly diagnosed with breast cancer","volume":"30","author":"Al-Hilli","year":"2023","journal-title":"Ann Surg Oncol"},{"issue":"10","key":"10.1016\/j.bulcan.2024.07.005_bib0235","doi-asserted-by":"crossref","first-page":"2271","DOI":"10.1093\/jamia\/ocae128","article-title":"A comparative evaluation of ChatGPT 3.5 and ChatGPT 4 in responses to selected genetics questions","volume":"31","author":"McGrath","year":"2024","journal-title":"J Am Med Inform Assoc"},{"issue":"8","key":"10.1016\/j.bulcan.2024.07.005_bib0240","doi-asserted-by":"crossref","first-page":"e386","DOI":"10.1016\/S1470-2045(20)30219-9","article-title":"Hereditary diffuse gastric cancer: updated clinical practice guidelines","volume":"21","author":"Blair","year":"2020","journal-title":"Lancet Oncol"},{"issue":"1","key":"10.1016\/j.bulcan.2024.07.005_bib0245","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1038\/s41436-019-0596-9","article-title":"Cancer risks by gene, age, and gender in 6350\u00a0carriers of pathogenic mismatch repair variants: findings from the prospective Lynch syndrome database","volume":"22","author":"Dominguez-Valentin","year":"2020","journal-title":"Genet Med"}],"container-title":["Bulletin du Cancer"],"original-title":[],"language":"fr","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0007455124002807?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0007455124002807?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,3,4]],"date-time":"2025-03-04T21:14:10Z","timestamp":1741122850000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0007455124002807"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3]]},"references-count":49,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2025,3]]}},"alternative-id":["S0007455124002807"],"URL":"https:\/\/doi.org\/10.1016\/j.bulcan.2024.07.005","relation":{},"ISSN":["0007-4551"],"issn-type":[{"value":"0007-4551","type":"print"}],"subject":[],"published":{"date-parts":[[2025,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Chirurgie prophylactique et oncog\u00e9n\u00e9tique\u00a0: quel impact de l\u2019intelligence artificielle\u00a0?","name":"articletitle","label":"Article Title"},{"value":"Bulletin du Cancer","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bulcan.2024.07.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Soci\u00e9t\u00e9 Fran\u00e7aise du Cancer. Published by Elsevier Masson SAS. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}