{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T05:04:20Z","timestamp":1782968660341,"version":"3.54.5"},"reference-count":25,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2011,11,1]],"date-time":"2011-11-01T00:00:00Z","timestamp":1320105600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Burns"],"published-print":{"date-parts":[[2011,11]]},"DOI":"10.1016\/j.burns.2011.07.006","type":"journal-article","created":{"date-parts":[[2011,8,6]],"date-time":"2011-08-06T20:00:13Z","timestamp":1312660813000},"page":"1154-1160","source":"Crossref","is-referenced-by-count":37,"title":["Safety and potential anticoagulant effects of nebulised heparin in burns patients with inhalational injury at Singapore General Hospital Burns Centre"],"prefix":"10.1016","volume":"37","author":[{"given":"Lian Yee","family":"Yip","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yen Fang","family":"Lim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong Ngee","family":"Chan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.burns.2011.07.006_bib0005","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/j.burns.2008.06.014","article-title":"Multi-variate analysis of burns patients in the Singapore General Hospital Burns Centre (2003\u20132005)","volume":"35","author":"Chong","year":"2009","journal-title":"Burns"},{"issue":"6","key":"10.1016\/j.burns.2011.07.006_bib0010","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1016\/S0002-9610(05)80662-2","article-title":"Etiology and consequences of respiratory failure in thermally injured patients","volume":"166","author":"Hollingsed","year":"1993","journal-title":"Am J Surg"},{"issue":"2","key":"10.1016\/j.burns.2011.07.006_bib0015","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1097\/BCR.0B013E318031D049","article-title":"Pneumonia after inhalation injury","volume":"28","author":"Edelman","year":"2007","journal-title":"J Burn Care Res"},{"key":"10.1016\/j.burns.2011.07.006_bib0020","first-page":"19","article-title":"Acute respiratory distress syndrome (ARDS)","volume":"22","author":"Lacquiere","year":"2007","journal-title":"Update in Anaesthesia"},{"issue":"1","key":"10.1016\/j.burns.2011.07.006_bib0025","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1016\/j.burns.2006.07.007","article-title":"Respiratory management of inhalation injury","volume":"33","author":"Mlcak","year":"2007","journal-title":"Burns"},{"issue":"4","key":"10.1016\/j.burns.2011.07.006_bib0030","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1016\/S0305-4179(00)00130-3","article-title":"Heparin in the treatment of burns: a review","volume":"27","author":"Saliba","year":"2001","journal-title":"Burns"},{"issue":"2","key":"10.1016\/j.burns.2011.07.006_bib0035","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1097\/BCR.0b013e318198a268","article-title":"Influence of nebulized unfractionated heparin and N-acetylcysteine in acute lung injury after smoke inhalation injury","volume":"30","author":"Miller","year":"2009","journal-title":"J Burn Care Res"},{"issue":"1","key":"10.1016\/j.burns.2011.07.006_bib0040","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1191\/1460408605ta327oa","article-title":"Current concepts in the pathophysiology and treatment of inhalation injury","volume":"7","author":"Cancio","year":"2005","journal-title":"Trauma"},{"key":"10.1016\/j.burns.2011.07.006_bib0045","first-page":"125","article-title":"Pathophysiological basis of smoke inhalation injury","volume":"18","author":"Murakami","year":"2003","journal-title":"News Physiol Sci"},{"issue":"3","key":"10.1016\/j.burns.2011.07.006_bib0050","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1097\/00004630-199805000-00004","article-title":"Reduction in mortality in pediatric patients with inhalation injury with aerosolized heparin\/N-acetylcystine [correction of acetylcystine] therapy","volume":"19","author":"Desai","year":"1998","journal-title":"J Burn Care Rehabil"},{"issue":"3","key":"10.1016\/j.burns.2011.07.006_bib0055","doi-asserted-by":"crossref","first-page":"R64","DOI":"10.1186\/cc6894","article-title":"A phase 1 trial of nebulised heparin in acute lung injury","volume":"12","author":"Dixon","year":"2008","journal-title":"Crit Care"},{"issue":"4","key":"10.1016\/j.burns.2011.07.006_bib0060","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1183\/09031936.02.00105202","article-title":"Effect of inhaled heparin on lung function and coagulation in healthy volunteers","volume":"19","author":"Bendstrup","year":"2002","journal-title":"Eur Respir J"},{"issue":"10","key":"10.1016\/j.burns.2011.07.006_bib0065","doi-asserted-by":"crossref","first-page":"818","DOI":"10.1097\/00003246-198510000-00009","article-title":"APACHE II: a severity of disease classification system","volume":"13","author":"Knaus","year":"1985","journal-title":"Crit Care Med"},{"issue":"1","key":"10.1016\/j.burns.2011.07.006_bib0070","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1097\/BCR.0b013e3181923bd3","article-title":"Use of nebulized heparin in the treatment of smoke inhalation injury","volume":"30","author":"Enkhbaatar","year":"2009","journal-title":"J Burn Care Res"},{"issue":"2","key":"10.1016\/j.burns.2011.07.006_bib0075","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1097\/01.CCM.0000050444.52531.08","article-title":"Recombinant antithrombin attenuates pulmonary inflammation following smoke inhalation and pneumonia in sheep","volume":"31","author":"Murakami","year":"2003","journal-title":"Crit Care Med"},{"issue":"5","key":"10.1016\/j.burns.2011.07.006_bib0080","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1016\/0305-4179(81)90013-9","article-title":"Coagulation and platelet changes after thermal injury in man","volume":"7","author":"Bartlett","year":"1981","journal-title":"Burns"},{"issue":"7","key":"10.1016\/j.burns.2011.07.006_bib0085","doi-asserted-by":"crossref","first-page":"864","DOI":"10.4065\/82.7.864","article-title":"How to interpret and pursue an abnormal prothrombin time: activated partial thromboplastin time, and bleeding time in adults","volume":"82","author":"Kamal","year":"2007","journal-title":"Mayo Clin Proc"},{"issue":"2","key":"10.1016\/j.burns.2011.07.006_bib0090","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1183\/09031936.06.00069005","article-title":"Inhaled heparin in cystic fibrosis","volume":"27","author":"Serisier","year":"2006","journal-title":"Eur Respir J"},{"issue":"1","key":"10.1016\/j.burns.2011.07.006_bib0095","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1183\/09031936.01.17100360","article-title":"Nebulized heparin in Burkholderia cepacia colonized adult cystic fibrosis patients","volume":"17","author":"Ledson","year":"2001","journal-title":"Eur Respir J"},{"issue":"1 Suppl.","key":"10.1016\/j.burns.2011.07.006_bib0100","doi-asserted-by":"crossref","first-page":"176S","DOI":"10.1378\/chest.119.1_suppl.176S","article-title":"Antithrombotic therapy for venous thromboembolic disease","volume":"119","author":"Hyers","year":"2001","journal-title":"Chest"},{"issue":"4","key":"10.1016\/j.burns.2011.07.006_bib0105","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1007\/s00134-007-0976-5","article-title":"Early coagulation disorders after severe burn injury: impact on mortality","volume":"34","author":"Lavrentieva","year":"2008","journal-title":"Intens Care Med"},{"issue":"7\u20138","key":"10.1016\/j.burns.2011.07.006_bib0110","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1016\/S0305-4179(97)00031-4","article-title":"Blood platelets in severely injured burned patients","volume":"23","author":"Takashima","year":"1997","journal-title":"Burns"},{"issue":"6","key":"10.1016\/j.burns.2011.07.006_bib0115","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1016\/0022-4804(77)90101-9","article-title":"Hematologic changes following burns","volume":"22","author":"Caprini","year":"1977","journal-title":"J Surg Res"},{"issue":"1","key":"10.1016\/j.burns.2011.07.006_bib0120","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/j.burns.2003.09.010","article-title":"Don\u2019t miss HIT (heparin induced thrombocytopenia)","volume":"30","author":"Horner","year":"2004","journal-title":"Burns"},{"issue":"Suppl. 1","key":"10.1016\/j.burns.2011.07.006_bib0125","doi-asserted-by":"crossref","first-page":"S18","DOI":"10.1016\/j.burns.2004.10.005","article-title":"Epidemiology of burn injuries in Singapore from 1997 to 2003","volume":"31","author":"Song","year":"2005","journal-title":"Burns"}],"container-title":["Burns"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0305417911002051?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0305417911002051?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,11,30]],"date-time":"2018-11-30T22:50:32Z","timestamp":1543618232000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0305417911002051"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,11]]},"references-count":25,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2011,11]]}},"alternative-id":["S0305417911002051"],"URL":"https:\/\/doi.org\/10.1016\/j.burns.2011.07.006","relation":{},"ISSN":["0305-4179"],"issn-type":[{"value":"0305-4179","type":"print"}],"subject":[],"published":{"date-parts":[[2011,11]]}}}