{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,21]],"date-time":"2025-09-21T18:26:42Z","timestamp":1758479202442,"version":"3.40.5"},"reference-count":38,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2016,3,1]],"date-time":"2016-03-01T00:00:00Z","timestamp":1456790400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","burnsjournal.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Burns"],"published-print":{"date-parts":[[2016,3]]},"DOI":"10.1016\/j.burns.2015.08.008","type":"journal-article","created":{"date-parts":[[2016,1,15]],"date-time":"2016-01-15T15:26:53Z","timestamp":1452871613000},"page":"375-383","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"title":["Prednisolone but not selenium and rtPA reduces edema and improves angiogenesis after burn in mice"],"prefix":"10.1016","volume":"42","author":[{"given":"O.","family":"Goertz","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Over","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"von der Lohe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6603-0443","authenticated-orcid":false,"given":"H.","family":"Lauer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Ring","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Daigeler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Lehnhardt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2822-421X","authenticated-orcid":false,"given":"J.","family":"Kolbenschlag","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.burns.2015.08.008_bib0195","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1007\/s00268-004-1082-2","article-title":"State of the art in burn treatment","volume":"29","author":"Atiyeh","year":"2005","journal-title":"World J Surg"},{"key":"10.1016\/j.burns.2015.08.008_bib0200","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1016\/j.burns.2011.01.004","article-title":"Influence of anti-inflammatory and vasoactive drugs on microcirculation and angiogenesis after burn in mice","volume":"37","author":"Goertz","year":"2011","journal-title":"Burns J Int Soc Burn Inj"},{"key":"10.1016\/j.burns.2015.08.008_bib0205","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1007\/BF00203677","article-title":"Extended infusion of rtPA lysis of pulmonary emboli: influence of time after onset of symptoms on outcome","volume":"18","author":"Aschauer","year":"1995","journal-title":"Cardiovasc Intervent Radiol"},{"key":"10.1016\/j.burns.2015.08.008_bib0210","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1097\/01.sap.0000252065.90759.e6","article-title":"The pathogenesis of burn wound conversion","volume":"59","author":"Singh","year":"2007","journal-title":"Ann Plast Surg"},{"key":"10.1016\/j.burns.2015.08.008_bib0215","doi-asserted-by":"crossref","first-page":"1555","DOI":"10.1097\/CCM.0b013e31828a24c6","article-title":"The effect of selenium therapy on mortality in patients with sepsis syndrome: a systematic review and meta-analysis of randomized controlled trials","volume":"41","author":"Alhazzani","year":"2013","journal-title":"Crit Care Med"},{"key":"10.1016\/j.burns.2015.08.008_bib0220","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1177\/0115426506021005438","article-title":"Antioxidant micronutrients in major trauma and burns: evidence and practice","volume":"21","author":"Berger","year":"2006","journal-title":"Nutr Clin Pract"},{"key":"10.1016\/j.burns.2015.08.008_bib0225","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1097\/TA.0b013e3181e74c54","article-title":"The selenium status of pediatric patients with burn injuries","volume":"69","author":"Dylewski","year":"2010","journal-title":"J Trauma"},{"key":"10.1016\/j.burns.2015.08.008_bib0230","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1016\/j.burns.2004.11.010","article-title":"Alterations of antioxidant trace elements (Zn, Se, Cu) and related metallo-enzymes in plasma and tissues following burn injury in rats","volume":"31","author":"Agay","year":"2005","journal-title":"Burns J Int Soc Burn Inj"},{"key":"10.1016\/j.burns.2015.08.008_bib0235","doi-asserted-by":"crossref","first-page":"882","DOI":"10.1160\/TH02-09-0093","article-title":"Anti-oxidant ebselen delays microvascular thrombus formation in the rat cremaster muscle by inhibiting platelet P-selectin expression","volume":"90","author":"Lindenblatt","year":"2003","journal-title":"Thromb Haemost"},{"key":"10.1016\/j.burns.2015.08.008_bib0240","doi-asserted-by":"crossref","first-page":"1433","DOI":"10.1080\/00207450490509168","article-title":"Effects of sleep deprivation, nicotine, and selenium on wound healing in rats","volume":"114","author":"Gumustekin","year":"2004","journal-title":"Int J Neurosci"},{"key":"10.1016\/j.burns.2015.08.008_bib0245","doi-asserted-by":"crossref","first-page":"1177","DOI":"10.1097\/00006534-199510000-00027","article-title":"Preventing the infiltration of leukocytes by monoclonal antibody blocks the development of progressive ischemia in rat burns","volume":"96","author":"Choi","year":"1995","journal-title":"Plast Reconstr Surg"},{"key":"10.1016\/j.burns.2015.08.008_bib0250","doi-asserted-by":"crossref","first-page":"950","DOI":"10.1097\/01.TA.0000030626.84680.11","article-title":"Clinical effects of inhibiting leukocyte adhesion with monoclonal antibody to intercellular adhesion molecule-1 (enlimomab) in the treatment of partial-thickness burn injury","volume":"54","author":"Mileski","year":"2003","journal-title":"J Trauma"},{"key":"10.1016\/j.burns.2015.08.008_bib0255","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.mvr.2014.04.003","article-title":"Peptide XIB13 reduces capillary leak in a rodent burn model","volume":"93","author":"Goertz","year":"2014","journal-title":"Microvasc Res"},{"key":"10.1016\/j.burns.2015.08.008_bib0260","first-page":"e13","article-title":"Burn model for in vivo investigations of microcirculatory changes","volume":"9","author":"Goertz","year":"2009","journal-title":"Eplasty"},{"key":"10.1016\/j.burns.2015.08.008_bib0265","doi-asserted-by":"crossref","first-page":"1010","DOI":"10.1016\/j.burns.2012.02.018","article-title":"Extracorporeal shock waves improve angiogenesis after full thickness burn","volume":"38","author":"Goertz","year":"2012","journal-title":"Burns J Int Soc Burn Inj"},{"key":"10.1016\/j.burns.2015.08.008_bib0270","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/j.burns.2004.09.014","article-title":"New model for in vivo investigation after microvascular breakdown in burns: use of intravital fluorescent microscopy","volume":"31","author":"Langer","year":"2005","journal-title":"Burns J Int Soc Burn Inj"},{"key":"10.1016\/j.burns.2015.08.008_bib0275","doi-asserted-by":"crossref","first-page":"e395","DOI":"10.1016\/j.jss.2011.01.034","article-title":"Intravital pathophysiologic comparison of frostbite and burn injury in a murine model","volume":"167","author":"Goertz","year":"2011","journal-title":"J Surg Res"},{"key":"10.1016\/j.burns.2015.08.008_bib0280","doi-asserted-by":"crossref","first-page":"1365","DOI":"10.1016\/j.burns.2014.01.019","article-title":"Repetitive extracorporeal shock wave applications are superior in inducing angiogenesis after full thickness burn compared to single application","volume":"40","author":"Goertz","year":"2014","journal-title":"Burns J Int Soc Burn Inj"},{"key":"10.1016\/j.burns.2015.08.008_bib0285","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1016\/j.burns.2006.10.404","article-title":"Assessment of burn depth: a prospective, blinded comparison of laser Doppler imaging and videomicroscopy","volume":"33","author":"McGill","year":"2007","journal-title":"Burns J Int Soc Burn Inj"},{"key":"10.1016\/j.burns.2015.08.008_bib0290","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1097\/SAP.0b013e3181a1473b","article-title":"Orthogonal polarization spectral imaging: a tool for assessing burn depths?","volume":"64","author":"Goertz","year":"2010","journal-title":"Ann Plast Surg"},{"key":"10.1016\/j.burns.2015.08.008_bib0295","doi-asserted-by":"crossref","DOI":"10.1016\/j.burns.2014.01.019","article-title":"Repetitive extracorporeal shock wave applications are superior in inducing angiogenesis after full thickness burn compared to single application","author":"Goertz","year":"2014","journal-title":"Burns J Int Soc Burn Inj"},{"key":"10.1016\/j.burns.2015.08.008_bib0300","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1055\/s-0033-1363773","article-title":"Changes of oxygenation and hemoglobin-concentration in lower extremity free flaps during dangling","volume":"30","author":"Kolbenschlag","year":"2014","journal-title":"J Reconstr Microsurg"},{"key":"10.1016\/j.burns.2015.08.008_bib0305","doi-asserted-by":"crossref","first-page":"e311","DOI":"10.1097\/PRS.0b013e318172ae1f","article-title":"Acute burns","volume":"121","author":"Grunwald","year":"2008","journal-title":"Plast Reconstr Surg"},{"key":"10.1016\/j.burns.2015.08.008_bib0310","article-title":"Influence of ISDN, l-NAME and selenium on microcirculation, leukocyte endothelium interaction and angiogenesis after frostbite","author":"Goertz","year":"2014","journal-title":"Burns J Int Soc Burn Inj"},{"key":"10.1016\/j.burns.2015.08.008_bib0315","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1159\/000072750","article-title":"Key vitamins and trace elements in the critically ill","volume":"8","author":"Berger","year":"2003","journal-title":"Nestle Nutr Workshop Ser Clin Perform Programme"},{"key":"10.1016\/j.burns.2015.08.008_bib0320","doi-asserted-by":"crossref","first-page":"R153","DOI":"10.1186\/cc5084","article-title":"Reduction of nosocomial pneumonia after major burns by trace element supplementation: aggregation of two randomised trials","volume":"10","author":"Berger","year":"2006","journal-title":"Crit Care"},{"key":"10.1016\/j.burns.2015.08.008_bib0325","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1097\/00004630-200111000-00011","article-title":"Microvascular assessment of burn depth conversion during varying resuscitation conditions","volume":"22","author":"Kim","year":"2001","journal-title":"J Burn Care Rehabil"},{"key":"10.1016\/j.burns.2015.08.008_bib0330","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1097\/00006534-198008000-00002","article-title":"In vivo microcirculation of a scald burn and the progression of postburn dermal ischemia","volume":"66","author":"Boykin","year":"1980","journal-title":"Plast Reconstr Surg"},{"key":"10.1016\/j.burns.2015.08.008_bib0335","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1016\/0022-4804(92)90112-D","article-title":"Inhibition of leukocyte-endothelial adherence following thermal injury","volume":"52","author":"Mileski","year":"1992","journal-title":"J Surg Res"},{"key":"10.1016\/j.burns.2015.08.008_bib0340","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1016\/0305-4179(95)00130-1","article-title":"Effect of a bradykinin antagonist on the local inflammatory response following thermal injury","volume":"22","author":"Nwariaku","year":"1996","journal-title":"Burns J Int Soc Burn Inj"},{"issue":"Pt 3","key":"10.1016\/j.burns.2015.08.008_bib0345","first-page":"428","article-title":"The bradykinin antagonist Hoe 140 inhibits carrageenan- and thermically induced paw oedema in rats","volume":"38","author":"Wirth","year":"1992","journal-title":"Agents Actions Suppl"},{"key":"10.1016\/j.burns.2015.08.008_bib0350","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1016\/j.burns.2012.09.018","article-title":"Assessing paediatric scald injuries using laser speckle contrast imaging","volume":"39","author":"Lindahl","year":"2013","journal-title":"Burns J Int Soc Burn Inj"},{"key":"10.1016\/j.burns.2015.08.008_bib0355","first-page":"H157","article-title":"Leukocyte rolling: a prominent feature of venules in intact skin of anesthetized hairless mice","volume":"262","author":"Mayrovitz","year":"1992","journal-title":"Am J Physiol"},{"key":"10.1016\/j.burns.2015.08.008_bib0360","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/S0300-483X(03)00154-9","article-title":"Free radicals and lipid peroxidation mediated injury in burn trauma: the role of antioxidant therapy","volume":"189","author":"Horton","year":"2003","journal-title":"Toxicology"},{"key":"10.1016\/j.burns.2015.08.008_bib0365","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1002\/biof.5520140125","article-title":"The effect of a selenium supplementation on the outcome of patients with severe systemic inflammation, burn and trauma","volume":"14","author":"Gartner","year":"2001","journal-title":"Biofactors"},{"key":"10.1016\/j.burns.2015.08.008_bib0370","doi-asserted-by":"crossref","first-page":"1388","DOI":"10.1189\/jlb.0707497","article-title":"Selenium supplementation induces metalloproteinase-dependent l-selectin shedding from monocytes","volume":"83","author":"Ahrens","year":"2008","journal-title":"J Leukoc Biol"},{"key":"10.1016\/j.burns.2015.08.008_bib0375","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1089\/ars.2011.4145","article-title":"The role of selenium in inflammation and immunity: from molecular mechanisms to therapeutic opportunities","volume":"16","author":"Huang","year":"2012","journal-title":"Antioxid Redox Signal"},{"key":"10.1016\/j.burns.2015.08.008_bib0380","first-page":"1005","article-title":"The effect of selenium on immune functions of J774.1 cells","volume":"41","author":"Safir","year":"2003","journal-title":"Clin Chem Lab Med CCLM\/FESCC"}],"container-title":["Burns"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0305417915002326?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0305417915002326?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,9,3]],"date-time":"2019-09-03T14:58:15Z","timestamp":1567522695000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0305417915002326"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,3]]},"references-count":38,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2016,3]]}},"alternative-id":["S0305417915002326"],"URL":"https:\/\/doi.org\/10.1016\/j.burns.2015.08.008","relation":{},"ISSN":["0305-4179"],"issn-type":[{"type":"print","value":"0305-4179"}],"subject":[],"published":{"date-parts":[[2016,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Prednisolone but not selenium and rtPA reduces edema and improves angiogenesis after burn in mice","name":"articletitle","label":"Article Title"},{"value":"Burns","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.burns.2015.08.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2016 Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}