{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T15:47:40Z","timestamp":1791474460240,"version":"4.3.4"},"reference-count":50,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2018,12,1]],"date-time":"2018-12-01T00:00:00Z","timestamp":1543622400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.fr","clinicalkey.com.au","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Burns"],"published-print":{"date-parts":[[2018,12]]},"DOI":"10.1016\/j.burns.2018.03.003","type":"journal-article","created":{"date-parts":[[2018,10,25]],"date-time":"2018-10-25T12:48:25Z","timestamp":1540471705000},"page":"2018-2025","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"title":["Photographic evaluation of different adrenaline-containing tumescent solutions on skin graft donor site bleeding: A prospective randomised trial"],"prefix":"10.1016","volume":"44","author":[{"given":"Christopher Wei Guang","family":"Ho","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yee Onn","family":"Kok","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Si Jack","family":"Chong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.burns.2018.03.003_bib0005","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1186\/s13054-015-0961-2","article-title":"Burn wound healing and treatment: review and advancements","volume":"19","author":"Rowan","year":"2015","journal-title":"Crit Care"},{"issue":"3","key":"10.1016\/j.burns.2018.03.003_bib0010","first-page":"172","article-title":"Monitoring and treatment of coagulation abnormalities in burn patients. An international survey on current practices","volume":"29","author":"Lavrentieva","year":"2016","journal-title":"Ann Burns Fire Disasters"},{"issue":"4","key":"10.1016\/j.burns.2018.03.003_bib0015","first-page":"207","article-title":"A new algorithm for calculation of blood loss in excisional burn surgery","volume":"54","author":"Moran","year":"1988","journal-title":"Am Surg"},{"issue":"2","key":"10.1016\/j.burns.2018.03.003_bib0020","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/0305-4179(93)90036-8","article-title":"The estimation of blood loss during burns surgery","volume":"19","author":"Budny","year":"1993","journal-title":"Burns"},{"issue":"3","key":"10.1016\/j.burns.2018.03.003_bib0025","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1016\/j.amjsurg.2004.11.030","article-title":"Establishing transfusion needs in burn patients","volume":"189","author":"Criswell","year":"2005","journal-title":"Am J Surg"},{"issue":"8","key":"10.1016\/j.burns.2018.03.003_bib0030","doi-asserted-by":"crossref","first-page":"1721","DOI":"10.1016\/j.burns.2016.06.002","article-title":"Blood transfusions in severe burn patients: epidemiology and predictive factors","volume":"42","author":"Wu","year":"2016","journal-title":"Burns"},{"issue":"6","key":"10.1016\/j.burns.2018.03.003_bib0035","doi-asserted-by":"crossref","first-page":"1602","DOI":"10.1097\/01.CCM.0000217472.97524.0E","article-title":"Effect of blood transfusion on outcome after major burn injury: a multicenter study","volume":"34","author":"Palmieri","year":"2006","journal-title":"Crit Care Med"},{"issue":"6","key":"10.1016\/j.burns.2018.03.003_bib0040","doi-asserted-by":"crossref","first-page":"826","DOI":"10.1097\/01.BCR.0000245494.45125.3E","article-title":"Safe and successful restriction of transfusion in burn patients","volume":"27","author":"Kwan","year":"2006","journal-title":"J Burn Care Res"},{"issue":"9","key":"10.1016\/j.burns.2018.03.003_bib0045","doi-asserted-by":"crossref","first-page":"2302","DOI":"10.1097\/01.CCM.0000234034.51040.7F","article-title":"Red blood cell transfusions and nosocomial infections in critically ill patients","volume":"34","author":"Taylor","year":"2006","journal-title":"Crit Care Med"},{"issue":"6","key":"10.1016\/j.burns.2018.03.003_bib0050","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1056\/NEJM199902113400601","article-title":"A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care","volume":"340","author":"H\u00e9bert","year":"1999","journal-title":"N Engl J Med"},{"issue":"4","key":"10.1016\/j.burns.2018.03.003_bib0055","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1097\/SLA.0000000000002408","article-title":"Transfusion requirement in burn care evaluation (TRIBE): a multicenter randomized prospective trial of blood transfusion in major burn injury","volume":"266","author":"Palmieri","year":"2017","journal-title":"Ann Surg"},{"issue":"5","key":"10.1016\/j.burns.2018.03.003_bib0060","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1016\/j.burns.2011.01.016","article-title":"Red blood cell transfusion following burn","volume":"37","author":"Curinga","year":"2011","journal-title":"Burns"},{"issue":"1","key":"10.1016\/j.burns.2018.03.003_bib0065","doi-asserted-by":"crossref","first-page":"49","DOI":"10.7326\/0003-4819-157-1-201206190-00429","article-title":"Red blood cell transfusion: a clinical practice guideline from the AABB","volume":"157","author":"Carson","year":"2012","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.burns.2018.03.003_bib0070","doi-asserted-by":"crossref","first-page":"h1354","DOI":"10.1136\/bmj.h1354","article-title":"Restrictive versus liberal transfusion strategy for red blood cell transfusion: systematic review of randomised trials with meta-analysis and trial sequential analysis","volume":"350","author":"Holst","year":"2015","journal-title":"BMJ"},{"key":"10.1016\/j.burns.2018.03.003_bib0075","doi-asserted-by":"crossref","first-page":"i1351","DOI":"10.1136\/bmj.i1351","article-title":"Effect of restrictive versus liberal transfusion strategies on outcomes in patients with cardiovascular disease in a non-cardiac surgery setting: systematic review and meta-analysis","volume":"352","author":"Docherty","year":"2016","journal-title":"BMJ"},{"key":"10.1016\/j.burns.2018.03.003_bib0080","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1186\/1471-2482-11-15","article-title":"Topical haemostatic agents for skin wounds: a systematic review","volume":"11","author":"Groenewold","year":"2011","journal-title":"BMC Surg"},{"issue":"2","key":"10.1016\/j.burns.2018.03.003_bib0085","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1097\/00004630-200103000-00005","article-title":"Reduced blood loss during burn surgery","volume":"22","author":"Gomez","year":"2001","journal-title":"J Burn Care Rehabil"},{"issue":"7","key":"10.1016\/j.burns.2018.03.003_bib0090","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1016\/S0305-4179(02)00186-9","article-title":"The use of tourniquets in the excision of unexsanguinated extremity burn wounds","volume":"28","author":"O\u2019Mara","year":"2002","journal-title":"Burns"},{"issue":"4","key":"10.1016\/j.burns.2018.03.003_bib0095","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1016\/j.burns.2010.06.010","article-title":"Hemostasis in burn surgery\u2014a review","volume":"37","author":"Sterling","year":"2011","journal-title":"Burns"},{"issue":"Suppl. 4","key":"10.1016\/j.burns.2018.03.003_bib0100","doi-asserted-by":"crossref","first-page":"S50","DOI":"10.1016\/j.surg.2007.06.026","article-title":"The use of fibrin sealant in burn operations","volume":"142","author":"Foster","year":"2007","journal-title":"Surgery"},{"issue":"4","key":"10.1016\/j.burns.2018.03.003_bib0105","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1097\/01.SAP.0000041484.22953.6D","article-title":"Hemostatic effect of Vivostat patient-derived fibrin sealant on split-thickness skin graft donor sites","volume":"50","author":"Drake","year":"2003","journal-title":"Ann Plast Surg"},{"issue":"5","key":"10.1016\/j.burns.2018.03.003_bib0110","first-page":"416","article-title":"The role of topical thrombin in skin grafting","volume":"83","author":"Ofodile","year":"1991","journal-title":"J Natl Med Assoc"},{"issue":"3","key":"10.1016\/j.burns.2018.03.003_bib0115","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1016\/j.burns.2003.11.004","article-title":"A prospective double blind randomized study comparing the need for blood transfusion with terlipressin or a placebo during early excision and grafting of burns","volume":"30","author":"Mzezewa","year":"2004","journal-title":"Burns"},{"issue":"4","key":"10.1016\/j.burns.2018.03.003_bib0120","doi-asserted-by":"crossref","first-page":"353","DOI":"10.23736\/S0375-9393.16.10992-7","article-title":"Transfusion requirements in burn patients undergoing primary wound excision: effect of tranexamic acid","volume":"83","author":"Dominguez","year":"2017","journal-title":"Minerva Anestesiol"},{"issue":"4","key":"10.1016\/j.burns.2018.03.003_bib0125","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1177\/074880688700400403","article-title":"The tumescent technique for lipo-suction surgery","volume":"4","author":"Klein","year":"1987","journal-title":"Am J Cosmet Surg"},{"issue":"8","key":"10.1016\/j.burns.2018.03.003_bib0130","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1016\/S0305-4179(01)00057-2","article-title":"The tumescent technique to significantly reduce blood loss during burn surgery","volume":"27","author":"Robertson","year":"2001","journal-title":"Burns"},{"issue":"6","key":"10.1016\/j.burns.2018.03.003_bib0135","doi-asserted-by":"crossref","first-page":"1034","DOI":"10.1097\/00005373-200012000-00010","article-title":"Minimizing blood loss in burn surgery","volume":"49","author":"Cartotto","year":"2000","journal-title":"J Trauma"},{"issue":"1","key":"10.1016\/j.burns.2018.03.003_bib0140","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1097\/BCR.0b013e318204b39b","article-title":"Phenylephrine tumescence in split-thickness skin graft donor sites in surgery for burn injury\u2014a concentration finding study","volume":"32","author":"Mitchell","year":"2011","journal-title":"J Burn Care Res"},{"issue":"6","key":"10.1016\/j.burns.2018.03.003_bib0145","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1016\/0305-4179(92)90182-T","article-title":"A quantitative assessment of blood loss in burn wound excision and grafting","volume":"18","author":"Steadman","year":"1992","journal-title":"Burns"},{"issue":"3","key":"10.1016\/j.burns.2018.03.003_bib0150","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/j.burns.2008.06.019","article-title":"Haemostatic effects of adrenaline-lidocaine subcutaneous infiltration at donor sites","volume":"35","author":"Gacto","year":"2009","journal-title":"Burns"},{"issue":"3","key":"10.1016\/j.burns.2018.03.003_bib0155","first-page":"144","article-title":"Tumescent infiltration of lidocaine and adrenaline for burn surgery","volume":"24","author":"Gumus","year":"2011","journal-title":"Ann Burns Fire Disasters"},{"issue":"2","key":"10.1016\/j.burns.2018.03.003_bib0160","doi-asserted-by":"crossref","first-page":"e34131","DOI":"10.5812\/traumamon.34131","article-title":"Blood loss estimation using gauze visual analogue","volume":"21","author":"Ali Algadiem","year":"2016","journal-title":"Trauma Mon"},{"issue":"3","key":"10.1016\/j.burns.2018.03.003_bib0165","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1097\/00000542-198303000-00016","article-title":"Estimating allowable blood loss: corrected for dilution","volume":"58","author":"Gross","year":"1983","journal-title":"Anesthesiology"},{"issue":"6","key":"10.1016\/j.burns.2018.03.003_bib0170","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1097\/BCR.0b013e31818b9e7a","article-title":"The practical procedure of tumescent technique in burn surgery for excision of burn eschar","volume":"29","author":"Fujita","year":"2008","journal-title":"J Burn Care Res"},{"issue":"6","key":"10.1016\/j.burns.2018.03.003_bib0175","doi-asserted-by":"crossref","first-page":"1140","DOI":"10.1016\/j.burns.2015.03.010","article-title":"Vasoconstrictor clysis in burn surgery and its impact on outcomes: systematic review and meta-analysis","volume":"41","author":"Allorto","year":"2015","journal-title":"Burns"},{"issue":"2","key":"10.1016\/j.burns.2018.03.003_bib0180","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1097\/01.sap.0000143798.55846.8d","article-title":"Transfusion-free pediatric burn surgery: techniques and strategies","volume":"54","author":"Losee","year":"2005","journal-title":"Ann Plast Surg"},{"issue":"3","key":"10.1016\/j.burns.2018.03.003_bib0185","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1097\/01.PRS.0000131021.17800.BE","article-title":"Pharmacokinetics and safety of epinephrine use in liposuction","volume":"114","author":"Brown","year":"2004","journal-title":"Plast Reconstr Surg"},{"issue":"10","key":"10.1016\/j.burns.2018.03.003_bib0190","doi-asserted-by":"crossref","first-page":"1226","DOI":"10.1016\/j.bjps.2007.09.011","article-title":"Effects of lidocaine and epinephrine on cutaneous blood flow","volume":"61","author":"Ghali","year":"2008","journal-title":"J Plast Reconstr Aesthet Surg"},{"issue":"5","key":"10.1016\/j.burns.2018.03.003_bib0195","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1136\/rapm-00115550-199520050-00003","article-title":"Epinephrine prolongs duration of subcutaneous infiltration of local anesthesia in a dose-related manner. Correlation with magnitude of vasoconstriction","volume":"20","author":"Liu","year":"1995","journal-title":"Reg Anesth"},{"issue":"10","key":"10.1016\/j.burns.2018.03.003_bib0200","doi-asserted-by":"crossref","first-page":"1687","DOI":"10.1097\/00005537-200110000-00003","article-title":"Optimal concentration of epinephrine for vasoconstriction in ear surgery","volume":"111","author":"Gessler","year":"2001","journal-title":"Laryngoscope"},{"key":"10.1016\/j.burns.2018.03.003_bib0205","series-title":"Surgical management of the burn wound","author":"Heimbach","year":"1984"},{"issue":"6","key":"10.1016\/j.burns.2018.03.003_bib0210","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1016\/S0305-4179(99)00038-8","article-title":"Effect of topical and subcutaneous epinephrine in combination with topical thrombin in blood loss during immediate near-total burn wound excision in pediatric burned patients","volume":"25","author":"Barret","year":"1999","journal-title":"Burns"},{"issue":"2","key":"10.1016\/j.burns.2018.03.003_bib0215","doi-asserted-by":"crossref","first-page":"e80","DOI":"10.1097\/BCR.0b013e31825d5414","article-title":"Effect of subcutaneous epinephrine\/saline\/local anesthetic versus saline-only injection on split-thickness skin graft donor site perfusion, healing, and pain","volume":"34","author":"Blome-Eberwein","year":"2013","journal-title":"J Burn Care Res"},{"issue":"5","key":"10.1016\/j.burns.2018.03.003_bib0220","doi-asserted-by":"crossref","first-page":"1350","DOI":"10.1213\/ANE.0000000000001119","article-title":"Estimated maximal safe dosages of tumescent lidocaine","volume":"122","author":"Klein","year":"2016","journal-title":"Anesth Analg"},{"issue":"1","key":"10.1016\/j.burns.2018.03.003_bib0225","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1007\/s00540-011-1246-9","article-title":"Severe post-burn neck contracture release and skin graft harvest using tumescent local anaesthesia as the sole anesthetic technique","volume":"26","author":"Prasad","year":"2012","journal-title":"J Anesth"},{"issue":"5","key":"10.1016\/j.burns.2018.03.003_bib0230","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1097\/01.BCR.0000085847.47967.75","article-title":"What are the acute cardiovascular effects of subcutaneous and topical epinephrine for hemostasis during burn surgery?","volume":"24","author":"Cartotto","year":"2003","journal-title":"J Burn Care Rehabil"},{"issue":"6","key":"10.1016\/j.burns.2018.03.003_bib0235","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1054\/bjps.1999.3161","article-title":"Subcutaneous adrenaline infiltration in paediatric burn surgery","volume":"52","author":"Beausang","year":"1999","journal-title":"Br J Plast Surg"},{"issue":"8","key":"10.1016\/j.burns.2018.03.003_bib0240","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1016\/S0305-4179(99)00088-1","article-title":"Staged high-dose epinephrine clysis is safe and effective in extensive tangential burn excisions in children","volume":"25","author":"Sheridan","year":"1999","journal-title":"Burns"},{"issue":"6","key":"10.1016\/j.burns.2018.03.003_bib0245","doi-asserted-by":"crossref","first-page":"832","DOI":"10.1016\/j.burns.2008.10.001","article-title":"The effects of topical epinephrine on haemodynamics and markers of tissue perfusion in burned and non-burned patients requiring skin grafting","volume":"35","author":"Papp","year":"2009","journal-title":"Burns"},{"key":"10.1016\/j.burns.2018.03.003_bib0250","article-title":"Healing time correlates with the quality of scaring: results from a prospective randomized control donor site trial","author":"Werdin","year":"2017","journal-title":"Dermatol Surg"}],"container-title":["Burns"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0305417918301645?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0305417918301645?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,3]],"date-time":"2026-04-03T21:45:56Z","timestamp":1775252756000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0305417918301645"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,12]]},"references-count":50,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2018,12]]}},"alternative-id":["S0305417918301645"],"URL":"https:\/\/doi.org\/10.1016\/j.burns.2018.03.003","relation":{},"ISSN":["0305-4179"],"issn-type":[{"value":"0305-4179","type":"print"}],"subject":[],"published":{"date-parts":[[2018,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Photographic evaluation of different adrenaline-containing tumescent solutions on skin graft donor site bleeding: A prospective randomised trial","name":"articletitle","label":"Article Title"},{"value":"Burns","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.burns.2018.03.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Ltd and ISBI. All rights reserved.","name":"copyright","label":"Copyright"}]}}