{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T22:44:25Z","timestamp":1772145865435,"version":"3.50.1"},"reference-count":46,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2018,12,1]],"date-time":"2018-12-01T00:00:00Z","timestamp":1543622400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.fr","clinicalkey.com.au","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Burns"],"published-print":{"date-parts":[[2018,12]]},"DOI":"10.1016\/j.burns.2018.06.010","type":"journal-article","created":{"date-parts":[[2018,7,11]],"date-time":"2018-07-11T03:00:14Z","timestamp":1531278014000},"page":"1962-1972","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"title":["Care in patients with epidermal necrolysis in burn units. A nursing perspective"],"prefix":"10.1016","volume":"44","author":[{"given":"V.","family":"Lerma","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Mac\u00edas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Toro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Moscoso","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y.","family":"Alonso","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"O.","family":"Hern\u00e1ndez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.J.","family":"de Abajo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.burns.2018.06.010_bib0005","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1111\/j.1365-2133.1956.tb12766.x","article-title":"Toxic epidermal necrolysis: an eruption resembling scalding of the skin","volume":"68","author":"Lyell","year":"1956","journal-title":"Br J Dermatol"},{"issue":"December (24)","key":"10.1016\/j.burns.2018.06.010_bib0010","doi-asserted-by":"crossref","first-page":"1600","DOI":"10.1056\/NEJM199512143332404","article-title":"Medication use and the risk of Stevens\u2013Johnson syndrome or toxic epidermal necrolysis","volume":"333","author":"Roujeau","year":"1995","journal-title":"N Engl J Med"},{"key":"10.1016\/j.burns.2018.06.010_bib0015","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1001\/archderm.1993.01680220104023","article-title":"Clinical classification of cases of toxic epidermal necrolysis, Stevens\u2013Johnson syndrome, and erythema multiforme","volume":"129","author":"Bastuji-Garin","year":"1993","journal-title":"Arch Dermatol"},{"issue":"March (1)","key":"10.1016\/j.burns.2018.06.010_bib0020","doi-asserted-by":"crossref","first-page":"10","DOI":"10.12788\/j.sder.0058","article-title":"Stevens\u2013Johnson syndrome and toxic epidermal necrolysis: clinical patterns, diagnostic considerations, etiology, and therapeutic management","volume":"33","author":"Mockenhaupt","year":"2014","journal-title":"Semin Cutan Med Surg"},{"issue":"November (5)","key":"10.1016\/j.burns.2018.06.010_bib0025","doi-asserted-by":"crossref","first-page":"1250","DOI":"10.1111\/bjd.13989","article-title":"Epidermal necrolysis: 60 years of errors and advances","volume":"173","author":"Heng","year":"2015","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.burns.2018.06.010_bib0030","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1001\/archderm.1990.01670250043005","article-title":"Toxic epidermal necrolysis (Lyell syndrome): incidence and drug etiology in France, 1981\u20131985","volume":"126","author":"Roujeau","year":"1990","journal-title":"Arch Dermatol"},{"issue":"July (7)","key":"10.1016\/j.burns.2018.06.010_bib0035","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1016\/0895-4356(96)00035-2","article-title":"Epidemiology of erythema exsudativum multiforme majus, Stevens\u2013Johnson syndrome, and toxic epidermal necrolysis in Germany (1990\u20131992): structure and results of a population-based registry","volume":"49","author":"Rzany","year":"1996","journal-title":"J Clin Epidemiol"},{"issue":"May (5)","key":"10.1016\/j.burns.2018.06.010_bib0040","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1038\/jid.2012.510","article-title":"Comprehensive survival analysis of a cohort of patients with Stevens-Johnson syndrome and toxic epidermal necrolysis","volume":"133","author":"Sekula","year":"2013","journal-title":"J Invest Dermatol"},{"issue":"February (2)","key":"10.1016\/j.burns.2018.06.010_bib0045","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/j.annder.2010.10.029","article-title":"Stevens\u2013Johnson and Lyell syndromes: mucocutaneous and ocular sequels in 43 cases","volume":"138","author":"Fellahi","year":"2011","journal-title":"Ann Dermatol Venereol"},{"key":"10.1016\/j.burns.2018.06.010_bib0050","first-page":"S1","article-title":"Mortality and long-lasting sequelae in patients with severe cutaneous adverse reactions","volume":"17","author":"Mockenhaupt","year":"2008","journal-title":"Pharmacoepidemiol Drug Saf"},{"issue":"August (2)","key":"10.1016\/j.burns.2018.06.010_bib0055","article-title":"Toxic epidermal necrolysis: part II. Prognosis, sequelae, diagnosis, differential diagnosis, prevention, and treatment","volume":"69","author":"Schwartz","year":"2013","journal-title":"J Am Acad Dermatol"},{"issue":"December (12)","key":"10.1016\/j.burns.2018.06.010_bib0060","doi-asserted-by":"crossref","first-page":"1343","DOI":"10.1038\/nm.1884","article-title":"Granulysin is a key mediator for disseminated keratinocyte death in Stevens\u2013Johnson syndrome and toxic epidermal necrolysis","volume":"14","author":"Chung","year":"2008","journal-title":"Nat Med"},{"issue":"August (4)","key":"10.1016\/j.burns.2018.06.010_bib0065","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1097\/ACI.0b013e3283630cc2","article-title":"Toxic epidermal necrolysis: the year in review","volume":"13","author":"Lee","year":"2013","journal-title":"Curr Opin Allergy Clin Immunol"},{"key":"10.1016\/j.burns.2018.06.010_bib0070","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1097\/00000658-198611000-00001","article-title":"Improved bum center survival of patients with toxic epidermal necrolysis managed without corticosteroids","volume":"204","author":"Halebian","year":"1986","journal-title":"Ann Surg"},{"issue":"September (4)","key":"10.1016\/j.burns.2018.06.010_bib0075","doi-asserted-by":"crossref","first-page":"1018","DOI":"10.1097\/00006534-199809020-00014","article-title":"Toxic epidermal necrolysis syndrome: mortality rate reduced with early referral to regional burn center","volume":"102","author":"McGee","year":"1998","journal-title":"Plast Reconstr Surg"},{"key":"10.1016\/j.burns.2018.06.010_bib0080","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1097\/00004630-199709000-00008","article-title":"Toxic epidermal necrolysis","volume":"18","author":"Murphy","year":"1997","journal-title":"J Burn Care Rehabil"},{"issue":"6","key":"10.1016\/j.burns.2018.06.010_bib0085","doi-asserted-by":"crossref","first-page":"47","DOI":"10.4037\/ccn1997.17.6.47","article-title":"Toxic epidermal necrolysis: a critical care challenge","volume":"17","author":"Supple","year":"1997","journal-title":"Crit Care Nurse"},{"issue":"October (10)","key":"10.1016\/j.burns.2018.06.010_bib0090","doi-asserted-by":"crossref","first-page":"2092","DOI":"10.1016\/j.jid.2017.05.022","article-title":"Cyclosporine use in epidermal necrolysis is associated with an important mortality reduction: evidence from three different approaches","volume":"137","author":"Gonz\u00e1lez-Herrada","year":"2017","journal-title":"J Invest Dermatol."},{"key":"10.1016\/j.burns.2018.06.010_bib0095","first-page":"273","article-title":"Bum center care for patients with toxic epidermal necrolysis","volume":"180","author":"Kelemen","year":"1995","journal-title":"J Am Coll Surg"},{"key":"10.1016\/j.burns.2018.06.010_bib0100","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1001\/archderm.136.3.323","article-title":"Toxic epidermal necrolysis and Stevens\u2013Johnson syndrome: does early withdrawal of causative drugs decrease the risk of death?","volume":"136","author":"Garcia-Doval","year":"2000","journal-title":"Arch Dermatol"},{"issue":"June (3)","key":"10.1016\/j.burns.2018.06.010_bib0105","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1188\/07.CJON.333-336","article-title":"Toxic epidermal necrolysis","volume":"1","author":"Hartkopf Smith","year":"2007","journal-title":"Clin J Oncol Nurs"},{"issue":"August (4)","key":"10.1016\/j.burns.2018.06.010_bib0110","doi-asserted-by":"crossref","first-page":"26","DOI":"10.4037\/ccn2013555","article-title":"Supportive therapy for a patient with toxic epidermal necrolysis undergoing plasmapheresis","volume":"33","author":"Seczynska","year":"2013","journal-title":"Crit Care Nurse"},{"issue":"4","key":"10.1016\/j.burns.2018.06.010_bib0115","first-page":"174","article-title":"Cuidados de enfermer\u00eda en el paciente con necr\u00f3lisis epid\u00e9rmica t\u00f3xica","volume":"10","author":"Velasco","year":"1999","journal-title":"Enferm Intensiva"},{"issue":"January\/February","key":"10.1016\/j.burns.2018.06.010_bib0120","article-title":"Diagn\u00f3sticos de enfermagem para o paciente com necr\u00f3lise epid\u00e9rmica t\u00f3xica: estudo de caso","volume":"65","author":"Muritiba Carneiro","year":"2012","journal-title":"Rev Bras Enferm"},{"issue":"September\u2013October (5)","key":"10.1016\/j.burns.2018.06.010_bib0125","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1097\/WON.0b013e3181b414ed","article-title":"Topical treatment protocol for Stevens\u2013Johnson syndrome and toxic epidermal necrolysis: a brief report","volume":"36","author":"Evans","year":"2009","journal-title":"J Wound Ostomy Continence Nurs"},{"key":"10.1016\/j.burns.2018.06.010_bib0130","first-page":"10","article-title":"How far would you go to save someone\u2019s skin?","volume":"8","author":"Brown","year":"2009","journal-title":"Dermatol Nurs"},{"issue":"August (4)","key":"10.1016\/j.burns.2018.06.010_bib0135","doi-asserted-by":"crossref","first-page":"52","DOI":"10.4037\/ccn2012340","article-title":"Drug reaction, skin care, skin loss","volume":"32","author":"Cooper","year":"2012","journal-title":"Crit Care Nurse"},{"key":"10.1016\/j.burns.2018.06.010_bib0140","first-page":"34","article-title":"Les soins aux patients atteints de toxidermie s\u00e9v\u00e8re: questions sur","volume":"317","author":"Colin","year":"2013","journal-title":"L\u2019Infirmi\u00e8re Mag"},{"issue":"5","key":"10.1016\/j.burns.2018.06.010_bib0145","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1016\/S1130-8621(06)71229-3","article-title":"El s\u00edndrome de Lyell. Cuidados de enfermer\u00eda especializados","volume":"16","author":"Garc\u00eda-Romanillos","year":"2006","journal-title":"Enferm Clin"},{"key":"10.1016\/j.burns.2018.06.010_bib0150","unstructured":"PIELenRed consortium; 2016. http:\/\/pielenred.hol.es\/PIELenRed\/. [Accessed 13 May 2016]."},{"key":"10.1016\/j.burns.2018.06.010_bib0155","unstructured":"RegiSCAR. The RegiSCAR Project; 2016. http:\/\/www.regiscar.org\/. [Accessed 13 May 2016]."},{"key":"10.1016\/j.burns.2018.06.010_bib0160","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1111\/j.1365-4632.2012.05743.x","article-title":"Stevens\u2013Johnson syndrome and toxic epidermal necrolysis in sub-Saharan Africa: a multicentric study in four countries","volume":"52","author":"Saka","year":"2013","journal-title":"Int J Dermatol"},{"issue":"7","key":"10.1016\/j.burns.2018.06.010_bib0165","article-title":"Antiseptics for burns","author":"Norman","year":"2017","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.burns.2018.06.010_bib0170","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1097\/PRS.0b013e3181773d5d","article-title":"Antishear therapy for toxic epidermal necrolysis: an alternative treatment approach","volume":"122","author":"Dorafshar","year":"2008","journal-title":"Plast Reconstr Surg"},{"issue":"4","key":"10.1016\/j.burns.2018.06.010_bib0175","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.dsi.2013.09.008","article-title":"French referral center management of Stevens\u2013Johnson syndrome\/toxic epidermal necrolysis","volume":"31","author":"Valeyrie-Allanore","year":"2013","journal-title":"Dermatol Sin"},{"key":"10.1016\/j.burns.2018.06.010_bib0180","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1097\/SAP.0b013e31806bf446","article-title":"A critical evaluation of the use of biobrane as a biologic skin substitute: a versatile tool for the plastic and reconstructive surgeon","volume":"60","author":"Whitaker","year":"2008","journal-title":"Ann Plast Surg"},{"key":"10.1016\/j.burns.2018.06.010_bib0185","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1016\/j.burns.2007.06.008","article-title":"Toxic epidermal necrolysis: use of Biobrane\u00ae for skin coverage reduces pain, improves mobilisation and decreases infection in elderly patients","volume":"34","author":"Boorboor","year":"2008","journal-title":"Burns"},{"key":"10.1016\/j.burns.2018.06.010_bib0190","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/S0196-0644(05)81793-7","article-title":"Outpatient management of partial-thickness burns: Biobrane versus 1% silver sulfadiazine","volume":"19","author":"Gerding","year":"1990","journal-title":"Ann Emerg Med"},{"key":"10.1016\/j.burns.2018.06.010_bib0195","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1016\/j.survophthal.2009.03.004","article-title":"Amniotic membrane transplantation as a new therapy for the acute ocular manifestations of Stevens\u2013Johnson syndrome and toxic epidermal necrolysis","volume":"54","author":"Shay","year":"2009","journal-title":"Surv Ophthalmol"},{"key":"10.1016\/j.burns.2018.06.010_bib0200","doi-asserted-by":"crossref","first-page":"1394","DOI":"10.1097\/ICO.0b013e31823d02a8","article-title":"Indications and outcomes of amniotic membrane transplantation in the management of acute Stevens\u2013Johnson syndrome and toxic epidermal necrolysis: a case\u2013control study","volume":"31","author":"Hsu","year":"2012","journal-title":"Cornea"},{"key":"10.1016\/j.burns.2018.06.010_bib0205","doi-asserted-by":"crossref","first-page":"775","DOI":"10.3109\/02713683.2011.587935","article-title":"Stability of epitheliotrophic factors in autologous serum eye drops from chronic Stevens-Johnson syndrome dry eye compared to non-autoimmune dry eye","volume":"36","author":"Phasukkijwatana","year":"2011","journal-title":"Curr Eye Res"},{"key":"10.1016\/j.burns.2018.06.010_bib0210","first-page":"81","article-title":"Prevention of vulvovaginal sequelae in Stevens\u2013Johnson syndrome and toxic epidermal necrolysis","volume":"4","author":"Kaser","year":"2011","journal-title":"Rev Obstet Gynecol"},{"issue":"4","key":"10.1016\/j.burns.2018.06.010_bib0215","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1016\/j.burns.2015.12.001","article-title":"Burn unit care of Stevens\u2013Johnson syndrome\/toxic epidermal necrolysis: a survey","volume":"42","author":"Le","year":"2016","journal-title":"Burns"},{"issue":"July\u2013August (4)","key":"10.1016\/j.burns.2018.06.010_bib0220","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1097\/BCR.0b013e31829a4374","article-title":"The first reported case of ureteral perforation in a patient with severe toxic epidermal necrolysis syndrome","volume":"35","author":"Baccaro","year":"2014","journal-title":"J Burn Care Res"},{"key":"10.1016\/j.burns.2018.06.010_bib0225","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1016\/j.annder.2011.05.029","article-title":"Pain management in Stevens\u2013Johnson syndrome, toxic epidermal necrolysis and other blistering diseases","volume":"138","author":"Valeyrie-Allanore","year":"2011","journal-title":"Ann Dermatol Venereol"},{"issue":"6","key":"10.1016\/j.burns.2018.06.010_bib0230","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1007\/s40257-015-0158-0","article-title":"Stevens\u2013Johnson syndrome and toxic epidermal necrolysis: an update","volume":"16","author":"Dodiuk-Gad","year":"2015","journal-title":"Am J Clin Dermatol"}],"container-title":["Burns"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0305417918305205?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0305417918305205?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,11,5]],"date-time":"2020-11-05T13:44:54Z","timestamp":1604583894000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0305417918305205"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,12]]},"references-count":46,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2018,12]]}},"alternative-id":["S0305417918305205"],"URL":"https:\/\/doi.org\/10.1016\/j.burns.2018.06.010","relation":{},"ISSN":["0305-4179"],"issn-type":[{"value":"0305-4179","type":"print"}],"subject":[],"published":{"date-parts":[[2018,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Care in patients with epidermal necrolysis in burn units. A nursing perspective","name":"articletitle","label":"Article Title"},{"value":"Burns","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.burns.2018.06.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Ltd and ISBI. All rights reserved.","name":"copyright","label":"Copyright"}]}}