{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,3]],"date-time":"2026-04-03T20:30:49Z","timestamp":1775248249630,"version":"3.50.1"},"reference-count":53,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Burns"],"published-print":{"date-parts":[[2022,5]]},"DOI":"10.1016\/j.burns.2021.05.013","type":"journal-article","created":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T23:27:02Z","timestamp":1622590022000},"page":"662-671","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"title":["Effectiveness of artesunate combined with fractional CO2 laser in a hypertrophic scar model with underlying mechanism"],"prefix":"10.1016","volume":"48","author":[{"given":"Jinxia","family":"Zhang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuanglin","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhikuan","family":"Xia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhuoying","family":"Peng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7994-3807","authenticated-orcid":false,"given":"Wanting","family":"Luo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoxian","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rongya","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"January (1)","key":"10.1016\/j.burns.2021.05.013_bib0005","doi-asserted-by":"crossref","first-page":"S3","DOI":"10.1097\/DSS.0000000000000819","article-title":"L keloids and hypertrophic scars: pathophysiology, classification, and treatment","volume":"43","author":"Berman","year":"2017","journal-title":"Dermatol Surg"},{"issue":"10052","key":"10.1016\/j.burns.2021.05.013_bib0010","doi-asserted-by":"crossref","first-page":"1427","DOI":"10.1016\/S0140-6736(16)31406-4","article-title":"Hypertrophic scarring: the greatest unmet challenge after burn injury","volume":"388","author":"Finnerty","year":"2016","journal-title":"Lancet"},{"issue":"2","key":"10.1016\/j.burns.2021.05.013_bib0015","article-title":"The molecular basis of hypertrophic scars","volume":"4","author":"Zhu","year":"2016","journal-title":"Burns Trauma"},{"issue":"4","key":"10.1016\/j.burns.2021.05.013_bib0020","first-page":"324","article-title":"Advances in scar management: prevention and management of hypertrophic scars and keloids","volume":"24","author":"Toro","year":"2016","journal-title":"Curr Opin Otolaryngol Head Neck Surg"},{"issue":"2","key":"10.1016\/j.burns.2021.05.013_bib0025","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1002\/lsm.23201","article-title":"Laser treatment of traumatic scars and contractures: 2020 International Consensus Recommendations","volume":"52","author":"Seago","year":"2020","journal-title":"Lasers Surg Med"},{"issue":"4","key":"10.1016\/j.burns.2021.05.013_bib0030","doi-asserted-by":"crossref","first-page":"185","DOI":"10.12788\/j.sder.2017.030","article-title":"Laser advances in the treatment of burn and traumatic scars","volume":"36","author":"Khetarpal","year":"2017","journal-title":"Semin Cutan Med Surg"},{"issue":"July (14)","key":"10.1016\/j.burns.2021.05.013_bib0035","doi-asserted-by":"crossref","first-page":"4863","DOI":"10.3390\/ijms21144863","article-title":"Temporal TGF-\u03b21 supergene family signalling cues modulating tissue morphogenesis: chondrogenesis within a muscle tissue model?","volume":"21","author":"Xiong","year":"2020","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.burns.2021.05.013_bib0040","doi-asserted-by":"crossref","first-page":"4992","DOI":"10.2741\/3583","article-title":"BMP-7 as antagonist of organ fibrosis","volume":"14","author":"Weiskirchen","year":"2009","journal-title":"Front Biosci"},{"issue":"5\u20136","key":"10.1016\/j.burns.2021.05.013_bib0045","doi-asserted-by":"crossref","first-page":"173","DOI":"10.14712\/fb2018064050173","article-title":"TSG-6 induces apoptosis of human hypertrophic scar fibroblasts via activation of the Fas\/FasL signalling pathway","volume":"64","author":"Li","year":"2018","journal-title":"Folia Biol (Praha)"},{"issue":"May (3)","key":"10.1016\/j.burns.2021.05.013_bib0050","first-page":"213","article-title":"The effect of tunicamycin on Fas protein expression and its function in fibroblasts from hypertrophic scar and keloid","volume":"25","author":"Liu","year":"2009","journal-title":"Zhonghua Zheng Xing Wai Ke Za Zhi"},{"issue":"May (6)","key":"10.1016\/j.burns.2021.05.013_bib0055","doi-asserted-by":"crossref","first-page":"1714","DOI":"10.1097\/01.prs.0000258851.47193.06","article-title":"Fas-mediated apoptotic signal transduction in keloid and hypertrophic scar","volume":"119","author":"Lu","year":"2007","journal-title":"Plast Reconstr Surg"},{"issue":"4","key":"10.1016\/j.burns.2021.05.013_bib0060","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1089\/ten.tec.2017.0464","article-title":"Characterization of in vitro reconstructed human normotrophic, hypertrophic, and keloid scar models","volume":"24","author":"Limandjaja","year":"2018","journal-title":"Tissue Eng C Methods"},{"issue":"4","key":"10.1016\/j.burns.2021.05.013_bib0065","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1139\/cjpp-2016-0248","article-title":"miR-29b promotes skin wound healing and reduces excessive scar formation by inhibition of the TGF-beta1\/Smad\/CTGF signaling pathway","volume":"95","author":"Guo","year":"2017","journal-title":"Can J Physiol Pharmacol"},{"issue":"6","key":"10.1016\/j.burns.2021.05.013_bib0070","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1007\/s11560-010-0487-1","article-title":"Bone Morphogenetic Protein7 (BMP7)","volume":"5","author":"Bramlage","year":"2010","journal-title":"Der Nephrol"},{"issue":"April (4)","key":"10.1016\/j.burns.2021.05.013_bib0075","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1038\/nrendo.2016.12","article-title":"BMP signalling in skeletal development, disease and repair","volume":"12","author":"Salazar","year":"2016","journal-title":"Nat Rev Endocrinol"},{"issue":"December","key":"10.1016\/j.burns.2021.05.013_bib0080","doi-asserted-by":"crossref","first-page":"116957","DOI":"10.1016\/j.lfs.2019.116957","article-title":"BMP-7 inhibits renal fibrosis in diabetic nephropathy via miR-21 downregulation","volume":"238","author":"Liu","year":"2019","journal-title":"Life Sci"},{"issue":"January (1)","key":"10.1016\/j.burns.2021.05.013_bib0085","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1620\/tjem.244.1","article-title":"Exogenous BMP-7 facilitates the recovery of cardiac function after acute myocardial infarction through counteracting TGF-\u03b21 signaling pathway","volume":"244","author":"Jin","year":"2018","journal-title":"Tohoku J Exp Med"},{"issue":"July (7)","key":"10.1016\/j.burns.2021.05.013_bib0090","doi-asserted-by":"crossref","first-page":"964","DOI":"10.1038\/nm888","article-title":"BMP-7 counteracts TGF-beta1-induced epithelial-to-mesenchymal transition and reverses chronic renal injury","volume":"9","author":"Zeisberg","year":"2003","journal-title":"Nat Med"},{"issue":"March\u2013April (2)","key":"10.1016\/j.burns.2021.05.013_bib0095","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1111\/wrr.12015","article-title":"BMP-7 attenuates TGF-\u03b21-induced fibroblast-like differentiation of rat dermal papilla cells","volume":"21","author":"Bin","year":"2013","journal-title":"Wound Repair Regen"},{"issue":"August (2)","key":"10.1016\/j.burns.2021.05.013_bib0100","doi-asserted-by":"crossref","first-page":"1957","DOI":"10.3892\/mmr.2017.6779","article-title":"BMP-7 suppresses excessive scar formation by activating the BMP-7\/Smad1\/5\/8 signaling pathway","volume":"16","author":"Guo","year":"2017","journal-title":"Mol Med Rep"},{"issue":"April (2)","key":"10.1016\/j.burns.2021.05.013_bib0105","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1080\/19396368.2017.1422046","article-title":"The role of the Fas\/FasL signaling pathway in environmental toxicant-induced testicular cell apoptosis: an update","volume":"64","author":"Wang","year":"2018","journal-title":"Syst Biol Reprod Med"},{"issue":"April","key":"10.1016\/j.burns.2021.05.013_bib0110","doi-asserted-by":"crossref","first-page":"224","DOI":"10.3389\/fendo.2019.00224","article-title":"Molecular mechanisms and signaling pathways involved in sertoli cell proliferation","volume":"10","author":"Meroni","year":"2019","journal-title":"Front Endocrinol (Lausanne)"},{"issue":"July (13)","key":"10.1016\/j.burns.2021.05.013_bib0115","doi-asserted-by":"crossref","first-page":"1394","DOI":"10.1097\/01.BRS.0000129894.34550.48","article-title":"The role of Fas-mediated apoptosis after traumatic spinal cord injury","volume":"29","author":"Yoshino","year":"2004","journal-title":"Spine (Phila Pa 1976)"},{"issue":"February (2)","key":"10.1016\/j.burns.2021.05.013_bib0120","first-page":"154","article-title":"Effects of Huoxue Zhitong decoration on transmembrane protein I and II induced apoptosis of signal transmission of the epidural scar tissue","volume":"24","author":"Fan","year":"2011","journal-title":"Zhongguo Gu Shang"},{"issue":"January (1)","key":"10.1016\/j.burns.2021.05.013_bib0125","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1046\/j.1523-1747.2000.00819.x","article-title":"Somatic mutations of Fas (Apo-1\/CD95) gene in cutaneous squamous cell carcinoma arising from a burn scar","volume":"114","author":"Lee","year":"2000","journal-title":"J Invest Dermatol"},{"issue":"September (9)","key":"10.1016\/j.burns.2021.05.013_bib0130","first-page":"709","article-title":"The distrubution of cell cycle on fibrolasts derived from the pathlogical scars and analysis of Fas gene mutations in keloids using polymerse chain Reaction-based single-strand conformation polymorphism","volume":"80","author":"Lu","year":"2000","journal-title":"Zhonghua Yi Xue Za Zhi"},{"key":"10.1016\/j.burns.2021.05.013_bib0135","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1186\/1475-2875-12-388","article-title":"Further evidence for an anti-inflammatory role of artesunate in experimental cerebral malaria","volume":"12","author":"Miranda","year":"2013","journal-title":"Malar J"},{"issue":"1","key":"10.1016\/j.burns.2021.05.013_bib0140","first-page":"89","article-title":"Artemisinin and its synthetic derivatives as a possible therapy for cancer","volume":"6","author":"Konstat-Korzenny","year":"2018","journal-title":"Med Sci (Basel)"},{"key":"10.1016\/j.burns.2021.05.013_bib0145","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1016\/j.phymed.2015.08.002","article-title":"Artemisinin derivatives induce iron-dependent cell death (ferroptosis) in tumor cells","volume":"22","author":"Ooko","year":"2015","journal-title":"Phytomedicine"},{"key":"10.1016\/j.burns.2021.05.013_bib0150","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.ejphar.2018.10.048","article-title":"Artesunate inhibits fibroblasts proliferation and reduces surgery-induced epidural fibrosis via the autophagy-mediated p53\/p21waf1\/cip1 pathway","volume":"842","author":"Wan","year":"2019","journal-title":"Eur J Pharmacol"},{"issue":"10","key":"10.1016\/j.burns.2021.05.013_bib0155","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1007\/s00403-019-01960-7","article-title":"Effect of artesunate and relation with TGF-\u03b21 and SMAD3 signaling on experimental hypertrophic scar model in rabbit ear","volume":"311","author":"Nong","year":"2019","journal-title":"Arch Dermatol Res"},{"issue":"2","key":"10.1016\/j.burns.2021.05.013_bib0160","first-page":"185","article-title":"Expressions of the related genes in fibroblasts of human keloid and the effect of artesunate","volume":"29","author":"Xiao","year":"2013","journal-title":"Zhonghua Shao Shang Za Zhi"},{"issue":"24","key":"10.1016\/j.burns.2021.05.013_bib0165","first-page":"4601","article-title":"Inhibiting effects of Artemisinin on hypertrophic scar in rabbit ears","volume":"12","author":"Feng","year":"2008","journal-title":"Zhongguo Zuzhi Gongcheng Yanjiu yu Linchuang Kangfu"},{"key":"10.1016\/j.burns.2021.05.013_bib0170","doi-asserted-by":"crossref","first-page":"561","DOI":"10.3892\/etm.2017.4573","article-title":"Artesunate ameliorates lung fibrosis via inhibiting the Notch signaling pathway","volume":"14","author":"Liu","year":"2017","journal-title":"Exp Ther Med"},{"issue":"April (4)","key":"10.1016\/j.burns.2021.05.013_bib0175","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1007\/s11255-016-1232-0","article-title":"Artesunate attenuates unilateral ureteral obstruction-induced renal fibrosis by regulating the expressions of bone morphogenetic protein-7 and uterine sensitization-associated gene-1 in rats","volume":"48","author":"Cao","year":"2016","journal-title":"Int Urol Nephrol"},{"issue":"July","key":"10.1016\/j.burns.2021.05.013_bib0180","doi-asserted-by":"crossref","first-page":"104829","DOI":"10.1016\/j.phrs.2020.104829","article-title":"Novel use for old drugs: the emerging role of artemisinin and its derivatives in fibrosis","volume":"157","author":"Wang","year":"2020","journal-title":"Pharmacol Res"},{"issue":"April (2)","key":"10.1016\/j.burns.2021.05.013_bib0185","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1080\/08923973.2017.1386212","article-title":"Artesunate enhances \u03b3\u03b4 T-cell-mediated antitumor activity through augmenting \u03b3\u03b4 T-cell function and reversing immune escape of HepG2 cells","volume":"40","author":"Qian","year":"2018","journal-title":"Immunopharmacol Immunotoxicol"},{"issue":"January (1)","key":"10.1016\/j.burns.2021.05.013_bib0190","first-page":"93","article-title":"Effects of artesunate on eosinophil apoptosis and expressions of Fas and Bcl-2 proteins in asthmatic mice","volume":"40","author":"Wang","year":"2020","journal-title":"Nan Fang Yi Ke Da Xue Xue Bao"},{"issue":"May (1)","key":"10.1016\/j.burns.2021.05.013_bib0195","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1016\/j.bbrc.2016.04.109","article-title":"Artesunate inhibits adipogeneis in 3T3-L1 preadipocytes by reducing the expression and\/or phosphorylation levels of C\/EBP-a, PPAR-g, FAS, perilipin A, and STAT-3","volume":"474","author":"Jang","year":"2016","journal-title":"Biochem Biophys Res Commun"},{"issue":"May (5)","key":"10.1016\/j.burns.2021.05.013_bib0200","doi-asserted-by":"crossref","first-page":"3400","DOI":"10.1167\/iovs.12-11068","article-title":"The artemisinin derivative artesunate inhibits corneal neovascularization by inducing ROS-dependent apoptosis in vascular endothelial cells","volume":"54","author":"Cheng","year":"2013","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"June (12)","key":"10.1016\/j.burns.2021.05.013_bib0205","doi-asserted-by":"crossref","first-page":"767","DOI":"10.21037\/atm-20-4558","article-title":"Artesunate induces apoptosis and inhibits the proliferation, stemness, and tumorigenesis of leukemia","volume":"8","author":"Chen","year":"2020","journal-title":"Ann Transl Med"},{"issue":"12","key":"10.1016\/j.burns.2021.05.013_bib0210","doi-asserted-by":"crossref","first-page":"4974","DOI":"10.1364\/BOE.7.004974","article-title":"Fractional laser photothermolysis using Bessel beams","volume":"7","author":"Mignon","year":"2016","journal-title":"Biomed Opt Express"},{"issue":"1","key":"10.1016\/j.burns.2021.05.013_bib0215","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1007\/s10103-015-1824-4","article-title":"Treatment of hypertrophic scars and keloids by fractional carbon dioxide laser: a clinical, histological, and immunohistochemical study","volume":"31","author":"Azzam","year":"2016","journal-title":"Lasers Med Sci"},{"issue":"12","key":"10.1016\/j.burns.2021.05.013_bib0220","first-page":"36","article-title":"Efficacy of fractional carbon dioxide laser in the treatment of mature burn scars: a clinical, histopathological, and histochemical study","volume":"10","author":"El-Hoshy","year":"2017","journal-title":"J Clin Aesthet Dermatol"},{"issue":"4","key":"10.1016\/j.burns.2021.05.013_bib0225","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1080\/14764172.2017.1400173","article-title":"The clinical effectiveness and cost-effectiveness of fractional CO2 laser in acne scars and skin rejuvenation: a meta-analysis and economic evaluation","volume":"20","author":"Ansari","year":"2018","journal-title":"J Cosmet Laser Ther"},{"key":"10.1016\/j.burns.2021.05.013_bib0230","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1007\/s00266-016-0686-x","article-title":"Dermal remodeling of burn scar by fractional CO2 laser","volume":"40","author":"Lee","year":"2016","journal-title":"Aesthet Plast Surg"},{"issue":"5","key":"10.1016\/j.burns.2021.05.013_bib0235","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.1007\/s10103-017-2204-z","article-title":"Ultrapulsed fractional ablative carbon dioxide laser treatment of hypertrophic burn scars: evaluation of an in-patient controlled, standardized treatment approach","volume":"32","author":"Poetschke","year":"2017","journal-title":"Lasers Med Sci"},{"issue":"3","key":"10.1016\/j.burns.2021.05.013_bib0240","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1111\/jocd.12099","article-title":"Evaluation of the effect of fractional CO2 laser on histopathological picture and TGF-\u03b21 expression in hypertrophic scar","volume":"13","author":"Makboul","year":"2014","journal-title":"J Cosmet Dermatol"},{"issue":"4","key":"10.1016\/j.burns.2021.05.013_bib0245","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1139\/cjpp-2016-0248","article-title":"miR-29b promotes skin wound healing and reduces excessive scar formation by inhibition of the TGF-beta1\/Smad\/CTGF signaling pathway","volume":"95","author":"Guo","year":"2017","journal-title":"Can J Physiol Pharmacol"},{"issue":"2","key":"10.1016\/j.burns.2021.05.013_bib0250","first-page":"73","article-title":"The study of expression and distribution of PCNA in hypertrophic scar tissue","volume":"16","author":"Su","year":"2000","journal-title":"Zhonghua Zheng Xing Wai Ke Za Zhi"},{"issue":"August (6)","key":"10.1016\/j.burns.2021.05.013_bib0255","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1111\/ced.12327","article-title":"Treatment of nodular facial angiofibromas in tuberous sclerosis, using ultrapulse carbon dioxide laser","volume":"39","author":"Biondo","year":"2014","journal-title":"Clin Exp Dermatol"},{"issue":"2","key":"10.1016\/j.burns.2021.05.013_bib0260","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1089\/wound.2018.0828","article-title":"Animal models for studies of keloid scarring","volume":"8","author":"Supp","year":"2019","journal-title":"Adv Wound Care (New Rochelle)"},{"issue":"24","key":"10.1016\/j.burns.2021.05.013_bib0265","first-page":"4601","article-title":"Inhibiting effects of Artemisinin on hypertrophic scar in rabbit ears","volume":"12","author":"Feng","year":"2008","journal-title":"Zhongguo Zuzhi Gongcheng Yanjiu yu Linchuang Kangfu"}],"container-title":["Burns"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0305417921001352?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0305417921001352?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,5]],"date-time":"2025-10-05T08:18:19Z","timestamp":1759652299000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0305417921001352"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5]]},"references-count":53,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2022,5]]}},"alternative-id":["S0305417921001352"],"URL":"https:\/\/doi.org\/10.1016\/j.burns.2021.05.013","relation":{},"ISSN":["0305-4179"],"issn-type":[{"value":"0305-4179","type":"print"}],"subject":[],"published":{"date-parts":[[2022,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effectiveness of artesunate combined with fractional CO2 laser in a hypertrophic scar model with underlying mechanism","name":"articletitle","label":"Article Title"},{"value":"Burns","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.burns.2021.05.013","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}