{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T22:06:53Z","timestamp":1786658813105,"version":"build-2736575974"},"reference-count":47,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,1,21]],"date-time":"2024-01-21T00:00:00Z","timestamp":1705795200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100013072","name":"Major Science and Technology Project of Hainan Province","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100013072","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002767","name":"Hunan Provincial Science and Technology Department","doi-asserted-by":"publisher","award":["2020SK1010"],"award-info":[{"award-number":["2020SK1010"]}],"id":[{"id":"10.13039\/501100002767","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Burns"],"published-print":{"date-parts":[[2024,5]]},"DOI":"10.1016\/j.burns.2024.01.020","type":"journal-article","created":{"date-parts":[[2024,1,21]],"date-time":"2024-01-21T05:59:14Z","timestamp":1705816754000},"page":"980-990","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":11,"title":["The systemic inflammation indexes after admission predict in-hospital mortality in patients with extensive burns"],"prefix":"10.1016","volume":"50","author":[{"given":"Fuying","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Quanyong","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hao","family":"Peng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianda","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chi","family":"Zhong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geao","family":"Liang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wengjuan","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dan","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.burns.2024.01.020_bib1","first-page":"2361","article-title":"Immunological approaches and therapy in burns (Review)","volume":"20","author":"Boldeanu","year":"2020","journal-title":"Exp Ther Med"},{"key":"10.1016\/j.burns.2024.01.020_bib2","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1016\/j.burns.2019.08.019","article-title":"Impact of oral resuscitation on circulating and splenic leukocytes after burns","volume":"46","author":"Gomez","year":"2020","journal-title":"Burns"},{"key":"10.1016\/j.burns.2024.01.020_bib3","doi-asserted-by":"crossref","first-page":"1188","DOI":"10.1056\/NEJMc1909342","article-title":"Management of burns","volume":"381","author":"Legrand","year":"2019","journal-title":"New Engl J Med"},{"key":"10.1016\/j.burns.2024.01.020_bib4","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1093\/cid\/ciaa248","article-title":"Dysregulation of immune response in patients with coronavirus 2019 (COVID-19) in Wuhan, China","volume":"71","author":"Qin","year":"2020","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.burns.2024.01.020_bib5","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1161\/ATVBAHA.116.308198","article-title":"Monocyte conversion during inflammation and injury","volume":"37","author":"Kratofil","year":"2017","journal-title":"Arterioscl Throm Vas"},{"key":"10.1016\/j.burns.2024.01.020_bib6","doi-asserted-by":"crossref","DOI":"10.1016\/j.cyto.2017.09.013","article-title":"Platelet-derived chemokines in inflammation and atherosclerosis","volume":"122","author":"Bakogiannis","year":"2019","journal-title":"Cytokine"},{"issue":"8","key":"10.1016\/j.burns.2024.01.020_bib7","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1080\/00325481.2020.1764235","article-title":"Clinical significance of neutrophil-lymphocyte ratio and monocyte-lymphocyte ratio in women with hyperglycemia","volume":"132","author":"Wang","year":"2020","journal-title":"Postgrad Med"},{"key":"10.1016\/j.burns.2024.01.020_bib8","doi-asserted-by":"crossref","first-page":"474","DOI":"10.4149\/BLL_2021_078","article-title":"Neutrophil-to-lymphocyte ratio, past, present and future perspectives","volume":"122","author":"Zahorec","year":"2021","journal-title":"Bratisl Med J"},{"key":"10.1016\/j.burns.2024.01.020_bib9","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2020-048324","article-title":"Inflammation and nutrition-based biomarkers in the prognosis of oesophageal cancer: a systematic review and meta-analysis","volume":"11","author":"Jiang","year":"2021","journal-title":"BMJ Open"},{"key":"10.1016\/j.burns.2024.01.020_bib10","doi-asserted-by":"crossref","DOI":"10.1186\/s12916-020-01817-1","article-title":"Neutrophil to lymphocyte ratio and cancer prognosis: an umbrella review of systematic reviews and meta-analyses of observational studies","volume":"18","author":"Cupp","year":"2020","journal-title":"BMC Med"},{"key":"10.1016\/j.burns.2024.01.020_bib11","doi-asserted-by":"crossref","DOI":"10.1186\/s12885-019-5903-y","article-title":"Combined neutrophil-lymphocyte ratio and platelet-lymphocyte ratio predicts chemotherapy response and prognosis in patients with advanced gastric cancer","volume":"19","author":"Hirahara","year":"2019","journal-title":"BMC Cancer"},{"key":"10.1016\/j.burns.2024.01.020_bib12","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1007\/s00408-020-00386-7","article-title":"Blood cell count derived inflammation indexes in patients with idiopathic pulmonary fibrosis","volume":"198","author":"Zinellu","year":"2020","journal-title":"Lung"},{"key":"10.1016\/j.burns.2024.01.020_bib13","doi-asserted-by":"crossref","DOI":"10.1002\/brb3.2141","article-title":"Monocyte-to-lymphocyte ratio as a predictor of stroke-associated pneumonia: A retrospective study-based investigation","volume":"11","author":"Cao","year":"2021","journal-title":"Brain Behav"},{"key":"10.1016\/j.burns.2024.01.020_bib14","article-title":"Prognostic value of platelet count-related ratios on admission in patients with pyogenic liver abscess","volume":"22","author":"Li","year":"2022","journal-title":"BMC\u00a0Infect Dis"},{"key":"10.1016\/j.burns.2024.01.020_bib15","doi-asserted-by":"crossref","DOI":"10.3390\/molecules25235725","article-title":"The systemic inflammation index on admission predicts in-hospital mortality in COVID-19 patients","volume":"25","author":"Fois","year":"2020","journal-title":"Molecules"},{"key":"10.1016\/j.burns.2024.01.020_bib16","first-page":"33","article-title":"Value of neutrophil to lymphocytes and platelets ratio for predicting 28-day mortality in sepsis patients","volume":"33","author":"Liu","year":"2021","journal-title":"Zhonghua Wei Zhong Bing Ji Jiu Yi Xue"},{"issue":"6","key":"10.1016\/j.burns.2024.01.020_bib17","doi-asserted-by":"crossref","first-page":"1260","DOI":"10.1093\/jbcr\/iraa091","article-title":"Complete blood count and derived indices: evolution pattern and prognostic value in adult burned patients","volume":"41","author":"Angulo","year":"2020","journal-title":"J Burn Care Res"},{"key":"10.1016\/j.burns.2024.01.020_bib18","first-page":"57","article-title":"Significance of early lymphocyte-platelets ratio on the prognosis of patients with extensive burns","volume":"38","author":"Xu","year":"2022","journal-title":"Zhonghua Shao Shang Za Zhi"},{"key":"10.1016\/j.burns.2024.01.020_bib19","first-page":"1167","article-title":"Value of blood routine indexes and their ratios in judging the prognosis of adult patients with extensive burns","volume":"36","author":"Zheng","year":"2020","journal-title":"Zhonghua Shao Shang Za Zhi"},{"key":"10.1016\/j.burns.2024.01.020_bib20","first-page":"13","article-title":"Prognostic value of using neutrophil-lymphocyte ratio in patients with burn injury for the diagnosis of sepsis and bacteraemia","volume":"90","author":"Fuss","year":"2018","journal-title":"Pol J Surg"},{"key":"10.1016\/j.burns.2024.01.020_bib21","doi-asserted-by":"crossref","first-page":"tkaa47","DOI":"10.1093\/burnst\/tkaa047","article-title":"The pathogenesis and diagnosis of sepsis post burn injury","volume":"9","author":"Zhang","year":"2021","journal-title":"Burns Trauma"},{"key":"10.1016\/j.burns.2024.01.020_bib22","doi-asserted-by":"crossref","first-page":"1241","DOI":"10.1097\/SLA.0000000000001807","article-title":"Neutrophil dysfunction, immature granulocytes, and cell-free DNA are early biomarkers of sepsis in burn-injured patients: a prospective observational cohort study","volume":"265","author":"Hampson","year":"2017","journal-title":"Ann Surg"},{"key":"10.1016\/j.burns.2024.01.020_bib23","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1016\/j.intimp.2019.02.043","article-title":"Relation of neutrophil-to-lymphocyte ratio to acute kidney injury in patients with sepsis and septic shock: a retrospective study","volume":"70","author":"Bu","year":"2019","journal-title":"Int Immunopharmacol"},{"key":"10.1016\/j.burns.2024.01.020_bib24","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1007\/s10495-016-1325-3","article-title":"Apoptosis-induced lymphopenia in sepsis and other severe injuries","volume":"22","author":"Girardot","year":"2017","journal-title":"Apoptosis"},{"key":"10.1016\/j.burns.2024.01.020_bib25","doi-asserted-by":"crossref","first-page":"11","DOI":"10.5482\/HAMO-14-11-0073","article-title":"Platelet serotonin modulates immune functions","volume":"36","author":"Mauler","year":"2016","journal-title":"Hamostaseologie"},{"key":"10.1016\/j.burns.2024.01.020_bib26","article-title":"Severity of thermal burn injury is associated with systemic neutrophil activation","volume":"12","author":"Laggner","year":"2022","journal-title":"Sci Rep-UK"},{"key":"10.1016\/j.burns.2024.01.020_bib27","doi-asserted-by":"crossref","first-page":"1901","DOI":"10.1016\/j.burns.2019.07.014","article-title":"Natural kinetics of blood cells following major burn: Impact of early decreases in white blood cells and platelets as prognostic markers of mortality","volume":"45","author":"Osuka","year":"2019","journal-title":"Burns"},{"key":"10.1016\/j.burns.2024.01.020_bib28","doi-asserted-by":"crossref","DOI":"10.1155\/2021\/1762584","article-title":"Participation of monocyte subpopulations in progression of experimental endotoxemia (EE) and systemic inflammation","volume":"2021","author":"Radzyukevich","year":"2021","journal-title":"J Immunol Res"},{"key":"10.1016\/j.burns.2024.01.020_bib29","doi-asserted-by":"crossref","first-page":"448","DOI":"10.14740\/jocmr4240","article-title":"Use of neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios in COVID-19","volume":"12","author":"Chan","year":"2020","journal-title":"J Clin Med Res"},{"key":"10.1016\/j.burns.2024.01.020_bib30","doi-asserted-by":"crossref","DOI":"10.1186\/s13054-017-1821-z","article-title":"Prognostic value of platelet-to-lymphocyte ratios among critically ill patients with acute kidney injury","volume":"21","author":"Zheng","year":"2017","journal-title":"Crit Care"},{"key":"10.1016\/j.burns.2024.01.020_bib31","doi-asserted-by":"crossref","DOI":"10.1155\/2017\/3526460","article-title":"Diagnostic value of neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio in Crohn's disease","volume":"2017","author":"Feng","year":"2017","journal-title":"Gastroent Res Pract"},{"key":"10.1016\/j.burns.2024.01.020_bib32","doi-asserted-by":"crossref","DOI":"10.1186\/s12872-017-0618-y","article-title":"Association of Platelet to lymphocyte ratio with non-culprit atherosclerotic plaque vulnerability in patients with acute coronary syndrome: an optical coherence tomography study","volume":"17","author":"Wang","year":"2017","journal-title":"BMC Cardiovasc Disord"},{"key":"10.1016\/j.burns.2024.01.020_bib33","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1097\/CM9.0000000000000650","article-title":"Association of platelet to lymphocyte ratio with in-hospital major adverse cardiovascular events and the severity of coronary artery disease assessed by the Gensini score in patients with acute myocardial infarction","volume":"133","author":"Li","year":"2020","journal-title":"Chin Med J-Peking"},{"key":"10.1016\/j.burns.2024.01.020_bib34","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.intimp.2017.07.007","article-title":"Platelet-to-lymphocyte ratio (PLR) and neutrophil-to-lymphocyte ratio (NLR) are associated with chronic hepatitis B virus (HBV) infection","volume":"51","author":"Zhao","year":"2017","journal-title":"Int Immunopharmacol"},{"key":"10.1016\/j.burns.2024.01.020_bib35","doi-asserted-by":"crossref","first-page":"7061","DOI":"10.2147\/OTT.S176768","article-title":"Platelet-to-lymphocyte ratio and lymphocyte-to-white blood cell ratio predict the efficacy of neoadjuvant chemotherapy and the prognosis of locally advanced gastric cancer patients treated with the oxaliplatin and capecitabine regimen","volume":"11","author":"Tang","year":"2018","journal-title":"Oncotargets Ther"},{"key":"10.1016\/j.burns.2024.01.020_bib36","doi-asserted-by":"crossref","DOI":"10.7754\/Clin.Lab.2019.181226","article-title":"The relationship of neutrophil-to-lymphocyte ratio or platelet-to-lymphocyte ratio and pancreatic cancer in patients with type 2 diabetes","volume":"65","author":"Qin","year":"2019","journal-title":"Clin Lab"},{"key":"10.1016\/j.burns.2024.01.020_bib37","article-title":"Addition of admission lactate levels to Baux score improves mortality prediction in severe burns","volume":"11","author":"Steinvall","year":"2021","journal-title":"Sci Rep-UK"},{"key":"10.1016\/j.burns.2024.01.020_bib38","doi-asserted-by":"crossref","first-page":"1278","DOI":"10.1093\/jbcr\/irad075","article-title":"The revised baux score as a predictor of burn mortality: a systematic review and meta-analysis","volume":"44","author":"Edgar","year":"2023","journal-title":"J Burn Care Res"},{"key":"10.1016\/j.burns.2024.01.020_bib39","doi-asserted-by":"crossref","first-page":"1169","DOI":"10.1016\/j.burns.2015.02.017","article-title":"Validation of the prognostic burn index: a nationwide retrospective study","volume":"41","author":"Tagami","year":"2015","journal-title":"Burns"},{"key":"10.1016\/j.burns.2024.01.020_bib40","doi-asserted-by":"crossref","DOI":"10.1016\/j.heliyon.2022.e11498","article-title":"Predictive value of neutrophil-to-lymphocyte and platelet ratio in in-hospital mortality in septic patients","volume":"8","author":"Shi","year":"2022","journal-title":"Heliyon"},{"key":"10.1016\/j.burns.2024.01.020_bib41","article-title":"The usefulness of peripheral blood cell counts to distinguish COVID-19 from dengue during acute infection","volume":"7","author":"Osuna-Ramos","year":"2022","journal-title":"Trop Med Infect Dis"},{"key":"10.1016\/j.burns.2024.01.020_bib42","article-title":"The role of inflammatory indices in the outcome of COVID-19 cancer patients","volume":"39","author":"Nooh","year":"2021","journal-title":"Med Oncol"},{"key":"10.1016\/j.burns.2024.01.020_bib43","article-title":"The predictive value of hematological inflammatory markers for acute kidney injury and mortality in adults with hemophagocytic Lymphohistiocytosis: a retrospective analysis of 585 patients","volume":"122","author":"Chen","year":"2023","journal-title":"Int\u00a0Immunopharmacol"},{"key":"10.1016\/j.burns.2024.01.020_bib44","article-title":"Prognostic value of platelet count-related ratios on admission in patients with pyogenic liver abscess","volume":"22","author":"Li","year":"2022","journal-title":"BMC\u00a0Infect Dis"},{"key":"10.1016\/j.burns.2024.01.020_bib45","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0283356","article-title":"Admission NLPR predicts long-term mortality in patients with acute ischemic stroke: a retrospective analysis of the MIMIC-III database","volume":"18","author":"Su","year":"2023","journal-title":"PLoS One"},{"key":"10.1016\/j.burns.2024.01.020_bib46","doi-asserted-by":"crossref","DOI":"10.1186\/s13052-022-01400-9","article-title":"Predicting immunoglobulin resistance in Kawasaki disease: an assessment of neutrophil to lymphocyte platelet ratio","volume":"48","author":"Lu","year":"2022","journal-title":"Ital J Pediatr"},{"key":"10.1016\/j.burns.2024.01.020_bib47","doi-asserted-by":"crossref","first-page":"1207","DOI":"10.2217\/bmm-2020-0317","article-title":"Role of hematological parameters in COVID-19 patients in the emergency room","volume":"14","author":"Usul","year":"2020","journal-title":"Biomark Med"}],"container-title":["Burns"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0305417924000172?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0305417924000172?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,10,18]],"date-time":"2024-10-18T00:44:35Z","timestamp":1729212275000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0305417924000172"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5]]},"references-count":47,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2024,5]]}},"alternative-id":["S0305417924000172"],"URL":"https:\/\/doi.org\/10.1016\/j.burns.2024.01.020","relation":{},"ISSN":["0305-4179"],"issn-type":[{"value":"0305-4179","type":"print"}],"subject":[],"published":{"date-parts":[[2024,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The systemic inflammation indexes after admission predict in-hospital mortality in patients with extensive burns","name":"articletitle","label":"Article Title"},{"value":"Burns","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.burns.2024.01.020","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}