{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T06:47:32Z","timestamp":1792478852841,"version":"4.5.0"},"reference-count":40,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,12,10]],"date-time":"2026-12-10T00:00:00Z","timestamp":1796860800000},"content-version":"am","delay-in-days":312,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100000005","name":"US Department of Defense","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000005","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Burns"],"published-print":{"date-parts":[[2026,2]]},"DOI":"10.1016\/j.burns.2025.107825","type":"journal-article","created":{"date-parts":[[2025,12,8]],"date-time":"2025-12-08T16:03:57Z","timestamp":1765209837000},"page":"107825","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Human platelet lysate\u2013loaded collagen\u2013poloxamer foam dressing for the management of deep partial-thickness burns"],"prefix":"10.1016","volume":"52","author":[{"given":"Marc A.","family":"Thompson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-2322-4361","authenticated-orcid":false,"given":"David","family":"Larson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kim","family":"Brown","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donald","family":"Brown","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5009-9948","authenticated-orcid":false,"given":"Kristo","family":"Nuutila","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.burns.2025.107825_bib1","unstructured":"World Health Organization (WHO) fact sheet: \u3008https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/burns\u3009, visited 4\/22\/2025."},{"issue":"19","key":"10.1016\/j.burns.2025.107825_bib2","doi-asserted-by":"crossref","first-page":"3073","DOI":"10.3390\/cells11193073","article-title":"The Immune and Regenerative Response to Burn Injury","volume":"11","author":"Burgess","year":"2022","journal-title":"Cells"},{"key":"10.1016\/j.burns.2025.107825_bib3","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1038\/s41572-020-0145-5","article-title":"Burn injury","volume":"6","author":"Jeschke","year":"2020","journal-title":"Nat Rev Dis Prim"},{"issue":"2","key":"10.1016\/j.burns.2025.107825_bib4","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1097\/XCS.0000000000000707","article-title":"MAMSE. Putting medical boots on the ground: lessons from the war in ukraine and applications for future conflict with near-peer adversaries","volume":"237","author":"Epstein","year":"2023","journal-title":"J Am Coll Surg"},{"key":"10.1016\/j.burns.2025.107825_bib5","doi-asserted-by":"crossref","DOI":"10.1016\/j.surg.2025.109310","article-title":"Unique aspects of trauma due to thermobaric artillery weapon systems (specifically the Russian TOS-1A) during the war in Ukraine","volume":"182","author":"Epstein","year":"2025","journal-title":"Surgery"},{"issue":"9-10","key":"10.1016\/j.burns.2025.107825_bib6","doi-asserted-by":"crossref","first-page":"3034","DOI":"10.1093\/milmed\/usac114","article-title":"Evaluation of topical off-the-shelf therapies to improve prolonged field care of burn-injured service members","volume":"188","author":"Varon","year":"2023","journal-title":"Mil Med"},{"issue":"7-8","key":"10.1016\/j.burns.2025.107825_bib7","doi-asserted-by":"crossref","first-page":"1505","DOI":"10.1093\/milmed\/usad390","article-title":"Evaluation of topical off-the-shelf therapies to reduce the need to evacuate battlefield-injured warfighters","volume":"189","author":"Larson","year":"2024","journal-title":"Mil Med"},{"key":"10.1016\/j.burns.2025.107825_bib8","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/j.addr.2018.04.008","article-title":"Drug delivery systems and materials for wound healing applications","volume":"127","author":"Saghazadeh","year":"2018","journal-title":"Adv Drug Deliv Rev"},{"issue":"9","key":"10.1016\/j.burns.2025.107825_bib9","doi-asserted-by":"crossref","first-page":"2488","DOI":"10.3390\/jcm13092488","article-title":"Bioactive dressing: a new algorithm in wound healing","volume":"13","author":"Polverino","year":"2024","journal-title":"J Clin Med"},{"issue":"1","key":"10.1016\/j.burns.2025.107825_bib10","doi-asserted-by":"crossref","first-page":"71","DOI":"10.2217\/rme-2020-0065","article-title":"Platelet lysate: a promising candidate in regenerative medicine","volume":"16","author":"Meftahpour","year":"2021","journal-title":"Regen Med"},{"issue":"3","key":"10.1016\/j.burns.2025.107825_bib11","first-page":"161","article-title":"Human platelet lysate as a xeno free alternative of fetal bovine serum for the in vitro expansion of human mesenchymal stromal cells","volume":"10","author":"Mohammadi","year":"2016","journal-title":"Int J Hematol Oncol Stem Cell Res"},{"issue":"8","key":"10.1016\/j.burns.2025.107825_bib12","doi-asserted-by":"crossref","first-page":"4100","DOI":"10.3390\/ijms23084100","article-title":"Characterization of a human platelet lysate-loaded keratin hydrogel for wound healing applications in vitro","volume":"23","author":"Zuniga","year":"2022","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.burns.2025.107825_bib13","doi-asserted-by":"crossref","DOI":"10.1016\/j.exer.2021.108493","article-title":"Human platelet lysate delivered via an ocular wound chamber for the treatment of corneal epithelial injuries","volume":"206","author":"Griffith","year":"2021","journal-title":"Exp Eye Res"},{"issue":"3","key":"10.1016\/j.burns.2025.107825_bib14","doi-asserted-by":"crossref","DOI":"10.1016\/j.xops.2022.100176","article-title":"Cambium Dry Eye Study Group. A randomized trial of topical fibrinogen-depleted human platelet lysate treatment of dry eye secondary to chronic graft-versus-host disease","volume":"2","author":"Sugar","year":"2022","journal-title":"Ophthalmol Sci"},{"key":"10.1016\/j.burns.2025.107825_bib15","doi-asserted-by":"crossref","DOI":"10.1016\/j.jcot.2021.101534","article-title":"Human platelet lysate - a potent (and overlooked) orthobiologic","volume":"21","author":"da Fonseca","year":"2021","journal-title":"J Clin Orthop Trauma"},{"issue":"5","key":"10.1016\/j.burns.2025.107825_bib16","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0215667","article-title":"hPL promotes osteogenic differentiation of stem cells in 3D scaffolds","volume":"14","author":"Jafar","year":"2019","journal-title":"PLOS One"},{"issue":"6","key":"10.1016\/j.burns.2025.107825_bib17","doi-asserted-by":"crossref","first-page":"360","DOI":"10.3390\/gels8060360","article-title":"Poloxamer-based scaffolds for tissue engineering applications: a review","volume":"8","author":"Cui","year":"2022","journal-title":"Gels"},{"issue":"10","key":"10.1016\/j.burns.2025.107825_bib18","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1089\/wound.2018.0854","article-title":"Efficacy of poloxamer-based wound dressings on Acinetobacter baumanni Biofilms","volume":"8","author":"Salisbury","year":"2019","journal-title":"Adv Wound Care"},{"issue":"9","key":"10.1016\/j.burns.2025.107825_bib19","doi-asserted-by":"crossref","first-page":"4557","DOI":"10.1021\/acsbiomaterials.1c00600","article-title":"Development of poloxamer hydrogels containing antibacterial guanidine-based polymers for healing of full-thickness skin wound","volume":"7","author":"Feng","year":"2021","journal-title":"ACS Biomater Sci Eng"},{"issue":"12","key":"10.1016\/j.burns.2025.107825_bib20","doi-asserted-by":"crossref","first-page":"671","DOI":"10.3390\/pharmaceutics11120671","article-title":"Poloxamer hydrogels for biomedical applications","volume":"11","author":"Russo","year":"2019","journal-title":"Pharmaceutics"},{"issue":"1","key":"10.1016\/j.burns.2025.107825_bib21","doi-asserted-by":"crossref","DOI":"10.1016\/j.burns.2024.107303","article-title":"Development of an experimental heterogeneous burn wound model","volume":"51","author":"Neelon","year":"2025","journal-title":"Burns"},{"issue":"7-8","key":"10.1016\/j.burns.2025.107825_bib22","doi-asserted-by":"crossref","first-page":"1423","DOI":"10.1093\/milmed\/usad476","article-title":"Subcutaneous anti-inflammatory therapies to prevent burn progression in a swine model of contact burn injury","volume":"189","author":"Thompson","year":"2024","journal-title":"Mil Med"},{"issue":"3","key":"10.1016\/j.burns.2025.107825_bib23","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1093\/ilar\/ilu045","article-title":"Randomized block experimental designs can increase the power and reproducibility of laboratory animal experiments","volume":"55","author":"Festing","year":"2014","journal-title":"ILAR J"},{"key":"10.1016\/j.burns.2025.107825_bib24","doi-asserted-by":"crossref","unstructured":"van Baar M.E.Epidemiology of Scars and Their Consequences: Burn Scars. 2020 Dec 8. In: T\u00e9ot L., Mustoe T.A., Middelkoop E., Gauglitz G.G., editors. Textbook on Scar Management: State of the Art Management and Emerging Technologies [Internet]. Cham (CH): Springer; 2020. Chapter 5.","DOI":"10.1007\/978-3-030-44766-3_5"},{"issue":"1","key":"10.1016\/j.burns.2025.107825_bib25","doi-asserted-by":"crossref","DOI":"10.1088\/1758-5090\/acfc29","article-title":"Biomimetic human skin model patterned with rete ridges","volume":"16","author":"Nagarajan","year":"2023","journal-title":"Biofabrication"},{"issue":"7193","key":"10.1016\/j.burns.2025.107825_bib26","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1038\/nature07039","article-title":"Wound repair and regeneration","volume":"453","author":"Gurtner","year":"2008","journal-title":"Nature"},{"key":"10.1016\/j.burns.2025.107825_bib27","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.jss.2023.05.009","article-title":"Topical synthetic platelets loaded with gentamicin decrease bacteria in deep partial-thickness burns","volume":"291","author":"Valdera","year":"2023","journal-title":"J Surg Res"},{"key":"10.1016\/j.burns.2025.107825_bib28","doi-asserted-by":"crossref","DOI":"10.1093\/burnst\/tkaa028","article-title":"Platelet-rich plasma accelerates skin wound healing by promoting re-epithelialization","volume":"8","author":"Xu","year":"2020","journal-title":"Burns Trauma"},{"issue":"1","key":"10.1016\/j.burns.2025.107825_bib29","article-title":"Efficacy and safety of allogeneic platelet-rich plasma in chronic wound treatment: a meta-analysis of randomized controlled trials","volume":"14","author":"Li","year":"2024","journal-title":"Sci Rep"},{"issue":"6","key":"10.1016\/j.burns.2025.107825_bib30","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/j.bj.2019.05.002","article-title":"A randomized controlled trial of effectiveness of platelet-rich plasma gel and regular dressing on wound healing time in pilonidal sinus surgery: Role of different affecting factors","volume":"42","author":"Mohamadi","year":"2019","journal-title":"Biomed J"},{"issue":"17","key":"10.1016\/j.burns.2025.107825_bib31","doi-asserted-by":"crossref","first-page":"6284","DOI":"10.3390\/ijms21176284","article-title":"Human platelet lysate supports efficient expansion and stability of Wharton's Jelly mesenchymal stromal cells via active uptake and release of soluble regenerative factors","volume":"21","author":"Ca\u00f1as-Arboleda","year":"2020","journal-title":"Int J Mol Sci"},{"issue":"2","key":"10.1016\/j.burns.2025.107825_bib32","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1016\/j.jss.2008.07.040","article-title":"Efficacy of three topical hemostatic agents applied by medics in a lethal groin injury model","volume":"154","author":"Sohn","year":"2009","journal-title":"J Surg Res"},{"issue":"8","key":"10.1016\/j.burns.2025.107825_bib33","doi-asserted-by":"crossref","first-page":"4100","DOI":"10.3390\/ijms23084100","article-title":"Characterization of a human platelet lysate-loaded keratin hydrogel for wound healing applications in vitro","volume":"23","author":"Zuniga","year":"2022","journal-title":"Int J Mol Sci"},{"issue":"9","key":"10.1016\/j.burns.2025.107825_bib34","doi-asserted-by":"crossref","first-page":"1519","DOI":"10.1359\/jbmr.080409","article-title":"PDGF receptor beta is a potent regulator of mesenchymal stromal cell function","volume":"23","author":"Tokunaga","year":"2008","journal-title":"J Bone Min Res"},{"issue":"7-8","key":"10.1016\/j.burns.2025.107825_bib35","doi-asserted-by":"crossref","first-page":"1505","DOI":"10.1093\/milmed\/usad390","article-title":"Evaluation of topical off-the-shelf therapies to reduce the need to evacuate battlefield-injured warfighters","volume":"189","author":"Larson","year":"2024","journal-title":"Mil Med"},{"issue":"19","key":"10.1016\/j.burns.2025.107825_bib36","doi-asserted-by":"crossref","first-page":"3073","DOI":"10.3390\/cells11193073","article-title":"The immune and regenerative response to burn injury","volume":"11","author":"Burgess","year":"2022","journal-title":"Cells"},{"issue":"5","key":"10.1016\/j.burns.2025.107825_bib37","doi-asserted-by":"crossref","first-page":"654","DOI":"10.3892\/etm.2022.11591","article-title":"Human placental mesenchymal stem cells regulate inflammation via the NF-\u03baB signaling pathway","volume":"24","author":"Liu","year":"2022","journal-title":"Exp Ther Med"},{"issue":"8","key":"10.1016\/j.burns.2025.107825_bib38","doi-asserted-by":"crossref","first-page":"3116","DOI":"10.1111\/iwj.14186","article-title":"Perilesional injections of human platelet lysate versus platelet poor plasma for the treatment of diabetic foot ulcers: a double-blinded prospective clinical trial","volume":"20","author":"Alhawari","year":"2023","journal-title":"Int Wound J"},{"issue":"1","key":"10.1016\/j.burns.2025.107825_bib39","article-title":"GelMA loaded with platelet lysate promotes skin regeneration and angiogenesis in pressure ulcers by activating STAT3","volume":"14","author":"Jin","year":"2024","journal-title":"Sci Rep"},{"key":"10.1016\/j.burns.2025.107825_bib40","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1016\/j.jss.2018.09.037","article-title":"Efficacy of gelatin hydrogel impregnated with concentrated platelet lysate in murine wound healing","volume":"234","author":"Notodihardjo","year":"2019","journal-title":"J Surg Res"}],"container-title":["Burns"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0305417925004541?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0305417925004541?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T23:04:25Z","timestamp":1773875065000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0305417925004541"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2]]},"references-count":40,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,2]]}},"alternative-id":["S0305417925004541"],"URL":"https:\/\/doi.org\/10.1016\/j.burns.2025.107825","relation":{},"ISSN":["0305-4179"],"issn-type":[{"value":"0305-4179","type":"print"}],"subject":[],"published":{"date-parts":[[2026,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Human platelet lysate\u2013loaded collagen\u2013poloxamer foam dressing for the management of deep partial-thickness burns","name":"articletitle","label":"Article Title"},{"value":"Burns","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.burns.2025.107825","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Ltd and ISBI. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"107825"}}