{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T19:04:29Z","timestamp":1790103869099,"version":"4.0.1"},"reference-count":70,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T00:00:00Z","timestamp":1773187200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006458","name":"Children's Hospital of Philadelphia","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006458","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000770","name":"University of Manchester","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000770","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"NHLBI","doi-asserted-by":"publisher","award":["R00 HL177827"],"award-info":[{"award-number":["R00 HL177827"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"NHLBI","doi-asserted-by":"publisher","award":["P01 HL046925"],"award-info":[{"award-number":["P01 HL046925"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"NHLBI","doi-asserted-by":"publisher","award":["R21 HL153409"],"award-info":[{"award-number":["R21 HL153409"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"NHLBI","doi-asserted-by":"publisher","award":["K99 HL156051"],"award-info":[{"award-number":["K99 HL156051"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"NHLBI","doi-asserted-by":"publisher","award":["K99 HL156052"],"award-info":[{"award-number":["K99 HL156052"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008091","name":"University of Rochester","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008091","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006792","name":"Hartwell Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006792","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006329","name":"Association for the Advancement of Blood & Biotherapies","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006329","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Blood Vessels, Thrombosis & Hemostasis"],"published-print":{"date-parts":[[2026,5]]},"DOI":"10.1016\/j.bvth.2026.100157","type":"journal-article","created":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T23:16:38Z","timestamp":1773357398000},"page":"100157","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Cross-species comparison of platelet proteomes reveals developmentally regulated metabolic and inflammatory changes"],"prefix":"10.1016","volume":"3","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1830-9922","authenticated-orcid":false,"given":"Christopher S.","family":"Thom","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinyue","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1748-0894","authenticated-orcid":false,"given":"Henry A.","family":"Feldman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2372-6109","authenticated-orcid":false,"given":"Kathleen E.","family":"McGrath","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Preeti","family":"Maurya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hossein","family":"Fazelinia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9640-9158","authenticated-orcid":false,"given":"Lynn","family":"Spruce","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"O\u2019Reilly","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-8036-575X","authenticated-orcid":false,"given":"Amalia","family":"El Nems","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-9600-2643","authenticated-orcid":false,"given":"Jesselin Romero","family":"Escobar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7324-1049","authenticated-orcid":false,"given":"James","family":"Palis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Craig N.","family":"Morrell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0013-598X","authenticated-orcid":false,"given":"Martha","family":"Sola-Visner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donald E.","family":"Mager","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1230-504X","authenticated-orcid":false,"given":"Patricia E.","family":"Davenport","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bvth.2026.100157_bib1","doi-asserted-by":"crossref","DOI":"10.3389\/fped.2021.627715","article-title":"Hemostatic challenges in neonates","volume":"9","author":"Davenport","year":"2021","journal-title":"Front Pediatr"},{"issue":"5","key":"10.1016\/j.bvth.2026.100157_bib2","doi-asserted-by":"crossref","first-page":"F348","DOI":"10.1136\/fetalneonatal-2011-300763","article-title":"Thrombocytopaenia and intraventricular haemorrhage in very premature infants: a tale of two cities","volume":"97","author":"von Lindern","year":"2012","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"key":"10.1016\/j.bvth.2026.100157_bib3","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1182\/asheducation.V2012.1.512.3798533","article-title":"Thrombocytopenia, bleeding, and use of platelet transfusions in sick neonates","volume":"2012","author":"Stanworth","year":"2012","journal-title":"Hematol Am Soc Hematol Educ Program"},{"issue":"3","key":"10.1016\/j.bvth.2026.100157_bib4","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1038\/sj.jp.7211230","article-title":"Patterns of thrombocytosis and thrombocytopenia in hospitalized neonates","volume":"25","author":"McPherson","year":"2005","journal-title":"J Perinatol"},{"issue":"1","key":"10.1016\/j.bvth.2026.100157_bib5","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1542\/peds.2013-0372","article-title":"Intraventricular hemorrhage and neurodevelopmental outcomes in extreme preterm infants","volume":"133","author":"Bolisetty","year":"2014","journal-title":"Pediatrics"},{"issue":"1","key":"10.1016\/j.bvth.2026.100157_bib6","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1203\/PDR.0b013e3181c1b176","article-title":"Intraventricular hemorrhage in premature infants: mechanism of disease","volume":"67","author":"Ballabh","year":"2010","journal-title":"Pediatr Res"},{"issue":"1","key":"10.1016\/j.bvth.2026.100157_bib7","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.clp.2013.09.007","article-title":"Pathogenesis and prevention of intraventricular hemorrhage","volume":"41","author":"Ballabh","year":"2014","journal-title":"Clin Perinatol"},{"issue":"3","key":"10.1016\/j.bvth.2026.100157_bib8","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1056\/NEJMoa1807320","article-title":"Randomized trial of platelet-transfusion thresholds in neonates","volume":"380","author":"Curley","year":"2019","journal-title":"N Engl J Med"},{"issue":"6","key":"10.1016\/j.bvth.2026.100157_bib9","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1161\/ATVBAHA.122.318162","article-title":"Transfusion of adult, but not neonatal, platelets promotes monocyte trafficking in neonatal mice","volume":"43","author":"Maurya","year":"2023","journal-title":"Arterioscler Thromb Vasc Biol"},{"issue":"5","key":"10.1016\/j.bvth.2026.100157_bib10","doi-asserted-by":"crossref","first-page":"1020","DOI":"10.1111\/j.1538-7836.2011.04233.x","article-title":"Effects of in vitro adult platelet transfusions on neonatal hemostasis","volume":"9","author":"Ferrer-Marin","year":"2011","journal-title":"J Thromb Haemost"},{"issue":"11","key":"10.1016\/j.bvth.2026.100157_bib11","doi-asserted-by":"crossref","first-page":"2814","DOI":"10.1111\/trf.12343","article-title":"Distinct differences in platelet production and function between neonates and adults: implications for platelet transfusion practice","volume":"53","author":"Ferrer-Marin","year":"2013","journal-title":"Transfusion"},{"issue":"1","key":"10.1016\/j.bvth.2026.100157_bib12","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1080\/09537104.2021.1962837","article-title":"Neonatal platelet physiology and implications for transfusion","volume":"33","author":"Ferrer-Marin","year":"2021","journal-title":"Platelets"},{"issue":"21","key":"10.1016\/j.bvth.2026.100157_bib13","doi-asserted-by":"crossref","first-page":"1439","DOI":"10.1182\/blood.V124.21.1439.1439","article-title":"P-selectin expression and platelet function are developmentally regulated","volume":"124","author":"Stolla","year":"2014","journal-title":"Blood"},{"issue":"4","key":"10.1016\/j.bvth.2026.100157_bib14","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1203\/00006450-199910000-00014","article-title":"Surface expression of major membrane glycoproteins on resting and TRAP-activated neonatal platelets","volume":"46","author":"Simak","year":"1999","journal-title":"Pediatr Res"},{"issue":"6","key":"10.1016\/j.bvth.2026.100157_bib15","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1055\/s-0038-1648990","article-title":"Neonatal platelets are less reactive than adult platelets to physiological agonists in whole blood","volume":"72","author":"Rajasekhar","year":"1994","journal-title":"Thromb Haemost"},{"issue":"9","key":"10.1016\/j.bvth.2026.100157_bib16","doi-asserted-by":"crossref","first-page":"S87","DOI":"10.1016\/j.exphem.2015.06.222","article-title":"P-selectin expression and platelet function are developmentally regulated","volume":"43","author":"Palis","year":"2015","journal-title":"Exp Hematol"},{"issue":"6","key":"10.1016\/j.bvth.2026.100157_bib17","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1111\/j.1651-2227.2001.tb02431.x","article-title":"Shorter PFA-100 closure times in neonates than in adults: role of red cells, white cells, platelets and von Willebrand factor","volume":"90","author":"Roschitz","year":"2001","journal-title":"Acta Paediatr"},{"issue":"2","key":"10.1016\/j.bvth.2026.100157_bib18","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1161\/CIRCRESAHA.121.319821","article-title":"Platelet and megakaryocyte roles in innate and adaptive immunity","volume":"130","author":"Koupenova","year":"2022","journal-title":"Circ Res"},{"issue":"4","key":"10.1016\/j.bvth.2026.100157_bib19","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/j.tmrv.2020.09.005","article-title":"The Immune Nature of Platelets Revisited","volume":"34","author":"Maouia","year":"2020","journal-title":"Transfus Med Rev"},{"issue":"1","key":"10.1016\/j.bvth.2026.100157_bib20","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1055\/s-2004-822974","article-title":"Platelets and angiogenesis in malignancy","volume":"30","author":"Sierko","year":"2004","journal-title":"Semin Thromb Hemost"},{"issue":"3","key":"10.1016\/j.bvth.2026.100157_bib21","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1038\/s41569-018-0110-0","article-title":"Platelet biology and functions: new concepts and clinical perspectives","volume":"16","author":"van der Meijden","year":"2019","journal-title":"Nat Rev Cardiol"},{"key":"10.1016\/j.bvth.2026.100157_bib22","doi-asserted-by":"crossref","first-page":"5","DOI":"10.3389\/fped.2020.00005","article-title":"Advantages and limitations of the neonatal immune system","volume":"8","author":"Tsafaras","year":"2020","journal-title":"Front Pediatr"},{"key":"10.1016\/j.bvth.2026.100157_bib23","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.mib.2020.05.011","article-title":"Neonatal gut microbiome and immunity","volume":"56","author":"Sanidad","year":"2020","journal-title":"Curr Opin Microbiol"},{"issue":"3","key":"10.1016\/j.bvth.2026.100157_bib24","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1097\/MPG.0000000000000597","article-title":"Why is initial bacterial colonization of the intestine important to infants' and children's health?","volume":"60","author":"Houghteling","year":"2015","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"10.1016\/j.bvth.2026.100157_bib25","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2020.597433","article-title":"CD71+ erythroid cells in human neonates exhibit immunosuppressive properties and compromise immune response against systemic infection in neonatal mice","volume":"11","author":"Elahi","year":"2020","journal-title":"Front Immunol"},{"issue":"5","key":"10.1016\/j.bvth.2026.100157_bib26","doi-asserted-by":"crossref","first-page":"1447","DOI":"10.1016\/j.jtha.2023.12.022","article-title":"Quantitative label-free mass spectrometry reveals content and signaling differences between neonatal and adult platelets","volume":"22","author":"Thom","year":"2024","journal-title":"J Thromb Haemost"},{"issue":"1","key":"10.1016\/j.bvth.2026.100157_bib27","doi-asserted-by":"crossref","DOI":"10.1080\/09537104.2023.2220415","article-title":"Proteomics-wise, how similar are mouse and human platelets?","volume":"34","author":"Martinez-Botia","year":"2023","journal-title":"Platelets"},{"issue":"10","key":"10.1016\/j.bvth.2026.100157_bib28","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1093\/intbio\/zyab016","article-title":"Translatable pathways classification (TransPath-C) for inferring processes germane to human biology from animal studies data: example application in neurobiology","volume":"13","author":"Carroll","year":"2021","journal-title":"Integr Biol (Camb)"},{"issue":"3","key":"10.1016\/j.bvth.2026.100157_bib29","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1038\/nprot.2017.147","article-title":"Proteome-wide identification of ubiquitin interactions using UbIA-MS","volume":"13","author":"Zhang","year":"2018","journal-title":"Nat Protoc"},{"issue":"D1","key":"10.1016\/j.bvth.2026.100157_bib30","doi-asserted-by":"crossref","first-page":"D419","DOI":"10.1093\/nar\/gky1038","article-title":"PANTHER version 14: more genomes, a new PANTHER GO-slim and improvements in enrichment analysis tools","volume":"47","author":"Mi","year":"2019","journal-title":"Nucleic Acids Res"},{"issue":"43","key":"10.1016\/j.bvth.2026.100157_bib31","doi-asserted-by":"crossref","first-page":"15545","DOI":"10.1073\/pnas.0506580102","article-title":"Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles","volume":"102","author":"Subramanian","year":"2005","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"5","key":"10.1016\/j.bvth.2026.100157_bib32","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1038\/ng0506-500","article-title":"GenePattern 2.0","volume":"38","author":"Reich","year":"2006","journal-title":"Nat Genet"},{"issue":"12","key":"10.1016\/j.bvth.2026.100157_bib33","doi-asserted-by":"crossref","first-page":"1739","DOI":"10.1093\/bioinformatics\/btr260","article-title":"Molecular signatures database (MSigDB) 3.0","volume":"27","author":"Liberzon","year":"2011","journal-title":"Bioinformatics"},{"issue":"10","key":"10.1016\/j.bvth.2026.100157_bib34","doi-asserted-by":"crossref","first-page":"1189","DOI":"10.6009\/jjrt.2023-2266","article-title":"[[Fundamentals] 5. Python+scikit-learn for machine learning in medical imaging]","volume":"79","author":"Tanaka","year":"2023","journal-title":"Nihon Hoshasen Gijutsu Gakkai Zasshi"},{"key":"10.1016\/j.bvth.2026.100157_bib35","article-title":"Sparse principal component analysis via variable projection","author":"Erichson","year":"2020","journal-title":"arXiv"},{"issue":"2","key":"10.1016\/j.bvth.2026.100157_bib36","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/j.imbio.2011.07.027","article-title":"Off to a slow start: under-development of the complement system in term newborns is more substantial following premature birth","volume":"217","author":"McGreal","year":"2012","journal-title":"Immunobiology"},{"issue":"5","key":"10.1016\/j.bvth.2026.100157_bib37","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1186\/gb-2006-7-5-216","article-title":"An overview of the serpin superfamily","volume":"7","author":"Law","year":"2006","journal-title":"Genome Biol"},{"issue":"10","key":"10.1016\/j.bvth.2026.100157_bib38","doi-asserted-by":"crossref","first-page":"1310","DOI":"10.1021\/acsptsci.3c00079","article-title":"The many faces of histidine triad nucleotide binding protein 1 (HINT1)","volume":"6","author":"Dillenburg","year":"2023","journal-title":"ACS Pharmacol Transl Sci"},{"issue":"11","key":"10.1016\/j.bvth.2026.100157_bib39","doi-asserted-by":"crossref","first-page":"2632","DOI":"10.1111\/jth.15847","article-title":"Age-restricted functional and developmental differences of neonatal platelets","volume":"20","author":"Liu","year":"2022","journal-title":"J Thromb Haemost"},{"issue":"5","key":"10.1016\/j.bvth.2026.100157_bib40","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.122943","article-title":"Platelet-derived \u03b22M regulates monocyte inflammatory responses","volume":"4","author":"Hilt","year":"2019","journal-title":"JCI Insight"},{"issue":"5","key":"10.1016\/j.bvth.2026.100157_bib41","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1161\/CIRCRESAHA.120.317119","article-title":"\u03b22M signals monocytes through non-canonical TGF\u03b2 receptor signal transduction","volume":"128","author":"Hilt","year":"2021","journal-title":"Circ Res"},{"issue":"11","key":"10.1016\/j.bvth.2026.100157_bib42","doi-asserted-by":"crossref","first-page":"1954","DOI":"10.1111\/jth.12404","article-title":"Platelet-derived CXCL12 (SDF-1\u03b1): basic mechanisms and clinical implications","volume":"11","author":"Chatterjee","year":"2013","journal-title":"J Thromb Haemost"},{"issue":"1","key":"10.1016\/j.bvth.2026.100157_bib43","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1182\/bloodadvances.2018020859","article-title":"Lin28b regulates age-dependent differences in murine platelet function","volume":"3","author":"Stolla","year":"2019","journal-title":"Blood Adv"},{"issue":"6","key":"10.1016\/j.bvth.2026.100157_bib44","doi-asserted-by":"crossref","first-page":"1076","DOI":"10.1161\/ATVBAHA.116.308464","article-title":"Maturation of platelet function during murine fetal development in vivo","volume":"37","author":"Margraf","year":"2017","journal-title":"Arterioscler Thromb Vasc Biol"},{"issue":"2","key":"10.1016\/j.bvth.2026.100157_bib45","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1111\/trf.70042","article-title":"Transfusion of adult platelets triggers inflammatory responses in newborn mice through both P-selectin-dependent and -independent mechanisms","volume":"66","author":"Davenport","year":"2025","journal-title":"Transfusion"},{"issue":"11","key":"10.1016\/j.bvth.2026.100157_bib46","doi-asserted-by":"crossref","first-page":"2079","DOI":"10.1160\/TH17-04-0241","article-title":"Down regulation of the Munc18b-syntaxin-11 Complex and \u03b21-tubulin impairs secretion and spreading in neonatal platelets","volume":"117","author":"Caparros-Perez","year":"2017","journal-title":"Thromb Haemost"},{"issue":"3","key":"10.1016\/j.bvth.2026.100157_bib47","doi-asserted-by":"crossref","first-page":"1224","DOI":"10.1038\/s41390-025-04676-9","article-title":"Effects of platelet transfusions on neonatal bleeding and inflammation","volume":"99","author":"Davenport","year":"2026","journal-title":"Pediatr Res"},{"key":"10.1016\/j.bvth.2026.100157_bib48","doi-asserted-by":"crossref","first-page":"47","DOI":"10.3389\/fphar.2020.00047","article-title":"Role of platelet-derived growth factor (PDGF) in asthma as an immunoregulatory factor mediating airway remodeling and possible pharmacological target","volume":"11","author":"Kardas","year":"2020","journal-title":"Front Pharmacol"},{"issue":"7","key":"10.1016\/j.bvth.2026.100157_bib49","doi-asserted-by":"crossref","first-page":"1461","DOI":"10.1111\/j.1538-7836.2006.01943.x","article-title":"Role of fibronectin assembly in platelet thrombus formation","volume":"4","author":"Cho","year":"2006","journal-title":"J Thromb Haemost"},{"issue":"37","key":"10.1016\/j.bvth.2026.100157_bib50","doi-asserted-by":"crossref","first-page":"32309","DOI":"10.1074\/jbc.M504460200","article-title":"Human acyl-CoA dehydrogenase-9 plays a novel role in the mitochondrial \u03b2-oxidation of unsaturated fatty acids","volume":"280","author":"Ensenauer","year":"2005","journal-title":"J Biol Chem"},{"key":"10.1016\/j.bvth.2026.100157_bib51","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2023.1160440","article-title":"Mitochondrial CPT1A: insights into structure, function, and basis for drug development","volume":"14","author":"Liang","year":"2023","journal-title":"Front Pharmacol"},{"issue":"14","key":"10.1016\/j.bvth.2026.100157_bib52","doi-asserted-by":"crossref","first-page":"9219","DOI":"10.1073\/pnas.142053899","article-title":"Interactions between Eph kinases and ephrins provide a mechanism to support platelet aggregation once cell-to-cell contact has occurred","volume":"99","author":"Prevost","year":"2002","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"28","key":"10.1016\/j.bvth.2026.100157_bib53","doi-asserted-by":"crossref","first-page":"9820","DOI":"10.1073\/pnas.0404065102","article-title":"Eph kinases and ephrins support thrombus growth and stability by regulating integrin outside-in signaling in platelets","volume":"102","author":"Prevost","year":"2005","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"13","key":"10.1016\/j.bvth.2026.100157_bib54","doi-asserted-by":"crossref","first-page":"3103","DOI":"10.1084\/jem.20071800","article-title":"Talin is required for integrin-mediated platelet function in hemostasis and thrombosis","volume":"204","author":"Petrich","year":"2007","journal-title":"J Exp Med"},{"issue":"3","key":"10.1016\/j.bvth.2026.100157_bib55","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1097\/MOH.0b013e3280ef68f8","article-title":"Calpain-mediated regulation of platelet signaling pathways","volume":"14","author":"Kuchay","year":"2007","journal-title":"Curr Opin Hematol"},{"issue":"6","key":"10.1016\/j.bvth.2026.100157_bib56","doi-asserted-by":"crossref","first-page":"2213","DOI":"10.1128\/MCB.21.6.2213-2220.2001","article-title":"Disruption of the mouse mu-calpain gene reveals an essential role in platelet function","volume":"21","author":"Azam","year":"2001","journal-title":"Mol Cell Biol"},{"issue":"6","key":"10.1016\/j.bvth.2026.100157_bib57","doi-asserted-by":"crossref","first-page":"1120","DOI":"10.1111\/j.1538-7836.2012.04715.x","article-title":"Targeted gene inactivation reveals a functional role of calpain-1 in platelet spreading","volume":"10","author":"Kuchay","year":"2012","journal-title":"J Thromb Haemost"},{"issue":"4","key":"10.1016\/j.bvth.2026.100157_bib58","doi-asserted-by":"crossref","first-page":"1241","DOI":"10.1182\/blood.V74.4.1241.1241","article-title":"Interleukin-6 is a potent thrombopoietic factor in vivo in mice","volume":"74","author":"Ishibashi","year":"1989","journal-title":"Blood"},{"issue":"11","key":"10.1016\/j.bvth.2026.100157_bib59","doi-asserted-by":"crossref","first-page":"766","DOI":"10.3390\/cells14110766","article-title":"IL-6 as a mediator of platelet hyper-responsiveness","volume":"14","author":"Webb","year":"2025","journal-title":"cells"},{"issue":"4","key":"10.1016\/j.bvth.2026.100157_bib60","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1161\/CIRCULATIONAHA.112.132126","article-title":"Signal transducer and activator of transcription 3 (STAT3) regulates collagen-induced platelet aggregation independently of its transcription factor activity","volume":"127","author":"Zhou","year":"2013","journal-title":"Circulation"},{"issue":"2","key":"10.1016\/j.bvth.2026.100157_bib61","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1055\/s-0038-1648857","article-title":"Platelet activation induced by interleukin-6: evidence for a mechanism involving arachidonic acid metabolism","volume":"72","author":"Oleksowicz","year":"1994","journal-title":"Thromb Haemost"},{"issue":"4","key":"10.1016\/j.bvth.2026.100157_bib62","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1136\/svn-2024-003574","article-title":"IRIS, a randomised, double-blind, placebo-controlled trial of interleukin-6 receptor inhibition undergoing endovascular treatment in acute anterior circulation ischaemic stroke: study rationale and design","volume":"10","author":"Chu","year":"2024","journal-title":"Stroke Vasc Neurol"},{"issue":"1","key":"10.1016\/j.bvth.2026.100157_bib63","doi-asserted-by":"crossref","first-page":"3037","DOI":"10.1038\/s41598-024-53087-z","article-title":"The association between tocilizumab therapy and the development of thrombosis in critically ill patients with COVID-19: a multicenter, cohort study","volume":"14","author":"Aljuhani","year":"2024","journal-title":"Sci Rep"},{"issue":"6","key":"10.1016\/j.bvth.2026.100157_bib64","doi-asserted-by":"crossref","first-page":"1248","DOI":"10.1016\/j.cell.2019.01.021","article-title":"VEGF in signaling and disease: beyond discovery and development","volume":"176","author":"Apte","year":"2019","journal-title":"Cell"},{"issue":"1","key":"10.1016\/j.bvth.2026.100157_bib65","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.jss.2011.04.043","article-title":"Mesenchymal-specific inhibition of vascular endothelial growth factor (VEGF) attenuates growth in neonatal mice","volume":"172","author":"Matthews","year":"2012","journal-title":"J Surg Res"},{"key":"10.1016\/j.bvth.2026.100157_bib66","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1007\/978-1-60761-500-2_21","article-title":"Impaired vascular endothelial growth factor signaling in the pathogenesis of neonatal pulmonary vascular disease","volume":"661","author":"Abman","year":"2010","journal-title":"Adv Exp Med Biol"},{"issue":"2","key":"10.1016\/j.bvth.2026.100157_bib67","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.jaapos.2017.11.009","article-title":"Longitudinal study of the association between thrombocytopenia and retinopathy of prematurity","volume":"22","author":"Jensen","year":"2018","journal-title":"J AAPOS"},{"issue":"1","key":"10.1016\/j.bvth.2026.100157_bib68","doi-asserted-by":"crossref","first-page":"e3","DOI":"10.1016\/j.jaapos.2011.01.015","article-title":"Thrombocytopenia and retinopathy of prematurity","volume":"15","author":"Jensen","year":"2011","journal-title":"J AAPOS"},{"issue":"1","key":"10.1016\/j.bvth.2026.100157_bib69","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1159\/000512282","article-title":"Decreased platelet counts and serum levels of VEGF-A, PDGF-BB, and BDNF in extremely preterm infants developing severe ROP","volume":"118","author":"Hellgren","year":"2021","journal-title":"Neonatology"},{"issue":"11","key":"10.1016\/j.bvth.2026.100157_bib70","doi-asserted-by":"crossref","first-page":"2300","DOI":"10.1111\/jth.14274","article-title":"Glucose metabolism and metabolic flexibility in blood platelets","volume":"16","author":"Aibibula","year":"2018","journal-title":"J Thromb Haemost"}],"container-title":["Blood Vessels, Thrombosis & Hemostasis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2950327226000227?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2950327226000227?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T15:20:02Z","timestamp":1779895202000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2950327226000227"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5]]},"references-count":70,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,5]]}},"alternative-id":["S2950327226000227"],"URL":"https:\/\/doi.org\/10.1016\/j.bvth.2026.100157","relation":{},"ISSN":["2950-3272"],"issn-type":[{"value":"2950-3272","type":"print"}],"subject":[],"published":{"date-parts":[[2026,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cross-species comparison of platelet proteomes reveals developmentally regulated metabolic and inflammatory changes","name":"articletitle","label":"Article Title"},{"value":"Blood Vessels, Thrombosis & Hemostasis","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bvth.2026.100157","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 American Society of Hematology. Published by Elsevier Inc. Licensed under Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0), permitting only noncommercial, nonderivative use with attribution. All other rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"100157"}}