{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T19:04:42Z","timestamp":1790881482995,"version":"4.1.0"},"reference-count":43,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2010,2,1]],"date-time":"2010-02-01T00:00:00Z","timestamp":1264982400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2010,2,1]],"date-time":"2010-02-01T00:00:00Z","timestamp":1264982400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100008363","name":"Kr\u00c3\u00a6ftens Bek\u00c3\u00a6mpelse","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008363","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cancer Epidemiology"],"published-print":{"date-parts":[[2010,2]]},"DOI":"10.1016\/j.canep.2009.12.012","type":"journal-article","created":{"date-parts":[[2010,1,9]],"date-time":"2010-01-09T04:26:45Z","timestamp":1263011205000},"page":"40-46","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":36,"title":["Micronutrient intake and risk of colon and rectal cancer in a Danish cohort"],"prefix":"10.1016","volume":"34","author":[{"given":"Nina","family":"Roswall","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anja","family":"Olsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jane","family":"Christensen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lars O.","family":"Dragsted","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kim","family":"Overvad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Tj\u00f8nneland","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"22","key":"10.1016\/j.canep.2009.12.012_bib1","doi-asserted-by":"crossref","first-page":"2274","DOI":"10.2174\/138161207781368783","article-title":"Current and future clinical strategies in colon cancer prevention and the emerging role of chemoprevention","volume":"13","author":"Boursi","year":"2007","journal-title":"Curr Pharm Des"},{"issue":"2","key":"10.1016\/j.canep.2009.12.012_bib2","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1081\/LESC-200038263","article-title":"Effect of diet, life style, and other environmental\/chemopreventive factors on colorectal cancer development, and assessment of the risks","volume":"22","author":"Ahmed","year":"2004","journal-title":"J Environ Sci Health C: Environ Carcinog Ecotoxicol Rev"},{"key":"10.1016\/j.canep.2009.12.012_bib3","series-title":"Food, Nutrition, Physical Activity and the prevention of cancer\u2014a global perspective","author":"World Cancer Research Fund","year":"2007"},{"issue":"February (5)","key":"10.1016\/j.canep.2009.12.012_bib4","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1002\/ijc.20648","article-title":"Folate intake and colorectal cancer risk: a meta-analytical approach","volume":"113","author":"Sanjoaquin","year":"2005","journal-title":"Int J Cancer"},{"issue":"1","key":"10.1016\/j.canep.2009.12.012_bib5","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/0009-2797(96)03729-5","article-title":"Oxidative stress associated with exercise, psychological stress and life-style factors","volume":"102","author":"Moller","year":"1996","journal-title":"Chem Biol Interact"},{"issue":"January (1)","key":"10.1016\/j.canep.2009.12.012_bib6","first-page":"53","article-title":"Influence of lifestyle on vitamin bioavailability","volume":"72","author":"van den","year":"2001","journal-title":"Int J Vitam Nutr Res"},{"issue":"March (3)","key":"10.1016\/j.canep.2009.12.012_bib7","doi-asserted-by":"crossref","first-page":"740","DOI":"10.1158\/1055-9965.EPI-04-0581","article-title":"A prospective study of dietary folate intake and risk of colorectal cancer: modification by caffeine intake and cigarette smoking","volume":"14","author":"Larsson","year":"2005","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"issue":"August (7)","key":"10.1016\/j.canep.2009.12.012_bib8","first-page":"617","article-title":"Effects of beta-carotene supplementation on cancer incidence by baseline characteristics in the Physicians\u2019 Health Study (United States)","volume":"11","author":"Cook","year":"2000","journal-title":"Cancer Causes Control"},{"issue":"June (21)","key":"10.1016\/j.canep.2009.12.012_bib9","doi-asserted-by":"crossref","first-page":"2351","DOI":"10.1001\/jama.297.21.2351","article-title":"Folic acid for the prevention of colorectal adenomas: a randomized clinical trial","volume":"297","author":"Cole","year":"2007","journal-title":"JAMA"},{"issue":"October (10)","key":"10.1016\/j.canep.2009.12.012_bib10","doi-asserted-by":"crossref","first-page":"1387","DOI":"10.1136\/gut.2006.095463","article-title":"Folate: a magic bullet or a double edged sword for colorectal cancer prevention?","volume":"55","author":"Kim","year":"2006","journal-title":"Gut"},{"issue":"July (7)","key":"10.1016\/j.canep.2009.12.012_bib11","doi-asserted-by":"crossref","first-page":"1325","DOI":"10.1158\/1055-9965.EPI-07-0329","article-title":"A temporal association between folic acid fortification and an increase in colorectal cancer rates may be illuminating important biological principles: a hypothesis","volume":"16","author":"Mason","year":"2007","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"issue":"April (4)","key":"10.1016\/j.canep.2009.12.012_bib12","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1097\/MEG.0b013e328306ccdb","article-title":"Colon cancer in Chile before and after the start of the flour fortification program with folic acid","volume":"21","author":"Hirsch","year":"2009","journal-title":"Eur J Gastroenterol Hepatol"},{"issue":"June (3)","key":"10.1016\/j.canep.2009.12.012_bib13","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1007\/PL00007387","article-title":"Beneficial role for folate in the prevention of colorectal and breast cancer","volume":"40","author":"Prinz-Langenohl","year":"2001","journal-title":"Eur J Nutr"},{"issue":"March (3)","key":"10.1016\/j.canep.2009.12.012_bib14","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1002\/mnfr.200600191","article-title":"Folate and colorectal cancer: an evidence-based critical review","volume":"51","author":"Kim","year":"2007","journal-title":"Mol Nutr Food Res"},{"key":"10.1016\/j.canep.2009.12.012_bib15","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1080\/14034940601047986","article-title":"Study design, exposure variables, and socioeconomic determinants of participation in diet, cancer and health: a population-based prospective cohort study of 57,053 men and women in Denmark","volume":"35","author":"Tjonneland","year":"2007","journal-title":"Scaninavian J Public Health"},{"issue":"December (4)","key":"10.1016\/j.canep.2009.12.012_bib16","doi-asserted-by":"crossref","first-page":"900","DOI":"10.1093\/ije\/20.4.900","article-title":"Development of a semiquantitative food frequency questionnaire to assess food, energy and nutrient intake in Denmark","volume":"20","author":"Overvad","year":"1991","journal-title":"Int J Epidemiol"},{"issue":"November (5)","key":"10.1016\/j.canep.2009.12.012_bib17","first-page":"535","article-title":"The Danish Cancer Registry\u2014history, content, quality and use","volume":"44","author":"Storm","year":"1997","journal-title":"Dan Med Bull"},{"key":"10.1016\/j.canep.2009.12.012_bib18","unstructured":"World Health Organization. International Statistical Classification of Diseases and Related Health Problems 10th Revision. http:\/\/wwwwhoint\/classifications\/apps\/icd\/icd10online 2009 [cited 2009 March 16]."},{"issue":"July (4)","key":"10.1016\/j.canep.2009.12.012_bib19","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1097\/00001648-199507000-00025","article-title":"Avoiding power loss associated with categorization and ordinal scores in dose-response and trend analysis","volume":"6","author":"Greenland","year":"1995","journal-title":"Epidemiology"},{"issue":"July (4)","key":"10.1016\/j.canep.2009.12.012_bib20","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1097\/00001648-199507000-00005","article-title":"Dose-response and trend analysis in epidemiology: alternatives to categorical analysis","volume":"6","author":"Greenland","year":"1995","journal-title":"Epidemiology"},{"issue":"December (4)","key":"10.1016\/j.canep.2009.12.012_bib21","doi-asserted-by":"crossref","first-page":"906","DOI":"10.1093\/ije\/20.4.906","article-title":"Validation of a semiquantitative food frequency questionnaire developed in Denmark","volume":"20","author":"Tjonneland","year":"1991","journal-title":"Int J Epidemiol"},{"issue":"August (4)","key":"10.1016\/j.canep.2009.12.012_bib22","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1093\/ije\/21.4.770","article-title":"Influence of individually estimated portion size data on the validity of a semiquantitative food frequency questionnaire","volume":"21","author":"Tjonneland","year":"1992","journal-title":"Int J Epidemiol"},{"issue":"August (4)","key":"10.1016\/j.canep.2009.12.012_bib23","first-page":"786","article-title":"Validity of individual portion size estimates in a food frequency questionnaire","volume":"23","author":"Haraldsdottir","year":"1994","journal-title":"Int J Epidemiol"},{"issue":"6","key":"10.1016\/j.canep.2009.12.012_bib24","doi-asserted-by":"crossref","DOI":"10.1079\/PHN2005883","article-title":"Validity of protein, retinol, folic acid and n-3 fatty acid intakes estimated from the food-frequency questionnaire used in the Danish National Birth Cohort","volume":"9","author":"Mikkelsen","year":"2006","journal-title":"Public Health Nutr"},{"issue":"September (3)","key":"10.1016\/j.canep.2009.12.012_bib25","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1079\/BJN2001414","article-title":"Dietary assessment in Whitehall II: comparison of 7 d diet diary and food-frequency questionnaire and validity against biomarkers","volume":"86","author":"Brunner","year":"2001","journal-title":"Br J Nutr"},{"issue":"April (4)","key":"10.1016\/j.canep.2009.12.012_bib26","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1079\/BJN2002518","article-title":"Validation of a short food frequency questionnaire to assess folate intake","volume":"87","author":"Pufulete","year":"2002","journal-title":"Br J Nutr"},{"key":"10.1016\/j.canep.2009.12.012_bib27","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1186\/1475-2891-4-26","article-title":"Validity of a self-administered food frequency questionnaire (FFQ) and its generalizability to the estimation of dietary folate intake in Japan","volume":"4","author":"Ishihara","year":"2005","journal-title":"Nutr J"},{"key":"10.1016\/j.canep.2009.12.012_bib28","series-title":"Nutritional Epidemiolgy","author":"Willet","year":"1998"},{"issue":"December (12)","key":"10.1016\/j.canep.2009.12.012_bib29","doi-asserted-by":"crossref","first-page":"1669","DOI":"10.1038\/sj.ejcn.1602021","article-title":"Sensitivity and specificity of self-reported use of dietary supplements","volume":"58","author":"Messerer","year":"2004","journal-title":"Eur J Clin Nutr"},{"issue":"September (9 Pt 2)","key":"10.1016\/j.canep.2009.12.012_bib30","first-page":"S46","article-title":"Influence of production, handling, and storage on phytonutrient content of foods","volume":"57","author":"Goldman","year":"1999","journal-title":"Nutr Rev"},{"issue":"January (3)","key":"10.1016\/j.canep.2009.12.012_bib31","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1002\/ijc.11540","article-title":"Comparison of risk factors for colon and rectal cancer","volume":"108","author":"Wei","year":"2004","journal-title":"Int J Cancer"},{"issue":"March (2)","key":"10.1016\/j.canep.2009.12.012_bib32","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/S1383-5718(98)00017-5","article-title":"In vitro antimutagenic and in vivo anticlastogenic effects of carotenoids and solvent extracts from fruits and vegetables rich in carotenoids","volume":"413","author":"Rauscher","year":"1998","journal-title":"Mutat Res"},{"issue":"December (6)","key":"10.1016\/j.canep.2009.12.012_bib33","doi-asserted-by":"crossref","first-page":"1074","DOI":"10.1093\/ajcn\/78.6.1074","article-title":"Vitamin C and cancer chemoprevention: reappraisal","volume":"78","author":"Lee","year":"2003","journal-title":"Am J Clin Nutr"},{"issue":"April (2)","key":"10.1016\/j.canep.2009.12.012_bib34","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1016\/j.clnu.2004.10.003","article-title":"Can oxidative damage be treated nutritionally?","volume":"24","author":"Berger","year":"2005","journal-title":"Clin Nutr"},{"issue":"July (28)","key":"10.1016\/j.canep.2009.12.012_bib35","doi-asserted-by":"crossref","first-page":"4492","DOI":"10.3748\/wjg.14.4492","article-title":"Folic acid supplementation inhibits recurrence of colorectal adenomas: a randomized chemoprevention trial","volume":"14","author":"Jaszewski","year":"2008","journal-title":"World J Gastroenterol"},{"issue":"May (5)","key":"10.1016\/j.canep.2009.12.012_bib36","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1136\/gut.2004.054718","article-title":"Effect of folic acid supplementation on genomic DNA methylation in patients with colorectal adenoma","volume":"54","author":"Pufulete","year":"2005","journal-title":"Gut"},{"issue":"January (1)","key":"10.1016\/j.canep.2009.12.012_bib37","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1111\/j.1572-0241.2001.03474.x","article-title":"Effects of folate supplementation on two provisional molecular markers of colon cancer: a prospective, randomized trial","volume":"96","author":"Kim","year":"2001","journal-title":"Am J Gastroenterol"},{"issue":"October (7)","key":"10.1016\/j.canep.2009.12.012_bib38","doi-asserted-by":"crossref","first-page":"517","DOI":"10.7326\/0003-4819-129-7-199810010-00002","article-title":"Multivitamin use, folate, and colon cancer in women in the Nurses\u2019 Health Study","volume":"129","author":"Giovannucci","year":"1998","journal-title":"Ann Intern Med"},{"issue":"March (3)","key":"10.1016\/j.canep.2009.12.012_bib39","first-page":"227","article-title":"The influence of folate and multivitamin use on the familial risk of colon cancer in women","volume":"11","author":"Fuchs","year":"2002","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"issue":"September","key":"10.1016\/j.canep.2009.12.012_bib40","doi-asserted-by":"crossref","first-page":"2725","DOI":"10.2741\/1431","article-title":"Chemopreventive role of folic acid in colorectal cancer","volume":"9","author":"Majumdar","year":"2004","journal-title":"Front Biosci"},{"issue":"April (3)","key":"10.1016\/j.canep.2009.12.012_bib41","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/j.alcohol.2005.03.012","article-title":"Effects of alcohol on folate metabolism: implications for carcinogenesis","volume":"35","author":"Mason","year":"2005","journal-title":"Alcohol"},{"issue":"February (2)","key":"10.1016\/j.canep.2009.12.012_bib42","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1158\/1055-9965.EPI-06-0054","article-title":"Folate supplementation: too much of a good thing?","volume":"15","author":"Ulrich","year":"2006","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"issue":"August (8)","key":"10.1016\/j.canep.2009.12.012_bib43","first-page":"946","article-title":"Screening for colon malignancy with colonoscopy","volume":"86","author":"Lieberman","year":"1991","journal-title":"Am J Gastroenterol"}],"container-title":["Cancer Epidemiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S187778210900191X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S187778210900191X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T05:23:02Z","timestamp":1761801782000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S187778210900191X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,2]]},"references-count":43,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2010,2]]}},"alternative-id":["S187778210900191X"],"URL":"https:\/\/doi.org\/10.1016\/j.canep.2009.12.012","relation":{},"ISSN":["1877-7821"],"issn-type":[{"value":"1877-7821","type":"print"}],"subject":[],"published":{"date-parts":[[2010,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Micronutrient intake and risk of colon and rectal cancer in a Danish cohort","name":"articletitle","label":"Article Title"},{"value":"Cancer Epidemiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.canep.2009.12.012","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2009 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}