{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T07:14:24Z","timestamp":1789456464493,"version":"build-2803163510"},"reference-count":54,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,9,1]],"date-time":"2016-09-01T00:00:00Z","timestamp":1472688000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,8,5]],"date-time":"2016-08-05T00:00:00Z","timestamp":1470355200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/3.0\/igo\/"}],"content-domain":{"domain":["cancerepidemiology.net","clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cancer Epidemiology"],"published-print":{"date-parts":[[2016,9]]},"DOI":"10.1016\/j.canep.2016.07.021","type":"journal-article","created":{"date-parts":[[2016,9,30]],"date-time":"2016-09-30T21:15:23Z","timestamp":1475270123000},"page":"S82-S89","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":19,"special_numbering":"S1","title":["Burden of gallbladder cancer in Central and South America"],"prefix":"10.1016","volume":"44","author":[{"given":"M.Isabel","family":"Izarzugaza","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leticia","family":"Fern\u00e1ndez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Forman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u00f3nica S.","family":"Sierra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.canep.2016.07.021_bib0005","first-page":"99","article-title":"Gallbladder cancer: epidemiology and outcome","volume":"6","author":"Hundal","year":"2014","journal-title":"Clin. Epidemiol."},{"issue":"6","key":"10.1016\/j.canep.2016.07.021_bib0010","doi-asserted-by":"crossref","first-page":"349","DOI":"10.3322\/canjclin.51.6.349","article-title":"Epidemiology and molecular pathology of gallbladder cancer","volume":"51","author":"Lazcano-Ponce","year":"2001","journal-title":"CA. Cancer J. Clin."},{"key":"10.1016\/j.canep.2016.07.021_bib0015","series-title":"Cancer Epidemiology and Prevention","first-page":"787","article-title":"Biliary tract cancer","author":"Hsing","year":"2006"},{"issue":"2","key":"10.1016\/j.canep.2016.07.021_bib0020","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1007\/s11894-005-0051-8","article-title":"Epidemiology and risk factors for gallstone disease: has the paradigm changed in the 21st century?","volume":"7","author":"Shaffer","year":"2005","journal-title":"Curr. Gastroenterol. Rep."},{"issue":"6","key":"10.1016\/j.canep.2016.07.021_bib0025","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1016\/j.ejso.2010.05.002","article-title":"Cholelithiasis in gallbladder cancer: coincidence, cofactor, or cause!","volume":"36","author":"Shrikhande","year":"2010","journal-title":"Eur. J. Surg. Oncol."},{"issue":"3","key":"10.1016\/j.canep.2016.07.021_bib0030","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1016\/j.ejso.2007.07.206","article-title":"Gallbladder carcinoma","volume":"34","author":"Miller","year":"2008","journal-title":"Eur. J. Surg. Oncol."},{"issue":"7","key":"10.1016\/j.canep.2016.07.021_bib0035","doi-asserted-by":"crossref","first-page":"1591","DOI":"10.1002\/ijc.21683","article-title":"Gallbladder cancer worldwide: geographical distribution and risk factors","volume":"118","author":"Randi","year":"2006","journal-title":"Int. J. Cancer"},{"issue":"11","key":"10.1016\/j.canep.2016.07.021_bib0040","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1111\/hpb.12046","article-title":"Modern perspectives on factors predisposing to the development of gallbladder cancer","volume":"15","author":"Pilgrim","year":"2013","journal-title":"HPB"},{"issue":"20","key":"10.1016\/j.canep.2016.07.021_bib0045","doi-asserted-by":"crossref","first-page":"2075","DOI":"10.1001\/jama.2015.4559","article-title":"Association of aflatoxin with gallbladder cancer in Chile","volume":"313","author":"Nogueira","year":"2015","journal-title":"JAMA"},{"issue":"10","key":"10.1016\/j.canep.2016.07.021_bib0050","doi-asserted-by":"crossref","first-page":"2446","DOI":"10.1002\/ijc.25421","article-title":"Gallbladder cancer: incidence and survival in a high-risk area of Chile","volume":"127","author":"Bertran","year":"2010","journal-title":"Int. J. Cancer"},{"key":"10.1016\/j.canep.2016.07.021_bib0055","series-title":"GLOBOCAN 2012 v1.0, Cancer Incidence and Mortality Worldwide: IARC CancerBase No. 11","author":"Ferlay","year":"2014"},{"key":"10.1016\/j.canep.2016.07.021_bib0060","volume":"Vol. X","year":"2014"},{"key":"10.1016\/j.canep.2016.07.021_bib0065","first-page":"565","article-title":"Gallbladder cancer: trend and risk distribution in Chile","volume":"134","author":"Andia","year":"2006","journal-title":"Rev. Med. Chil."},{"issue":"5","key":"10.1016\/j.canep.2016.07.021_bib0070","doi-asserted-by":"crossref","first-page":"283","DOI":"10.3322\/caac.21153","article-title":"Cancer statistics for Hispanics\/Latinos, 2012","volume":"62","author":"Siegel","year":"2012","journal-title":"CA. Cancer J. Clin."},{"issue":"10","key":"10.1016\/j.canep.2016.07.021_bib0075","first-page":"3156","article-title":"K-ras mutation, p53 overexpression, and microsatellite instability in biliary tract cancers: a population-based study in China","volume":"8","author":"Rashid","year":"2002","journal-title":"Clin. Cancer Res."},{"issue":"2","key":"10.1016\/j.canep.2016.07.021_bib0080","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1016\/j.jhep.2010.06.039","article-title":"Trends in the incidence and management of biliary tract cancer: a French population-based study","volume":"54","author":"Lepage","year":"2011","journal-title":"J. Hepatol."},{"issue":"3","key":"10.1016\/j.canep.2016.07.021_bib0085","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1002\/(SICI)1097-0215(19980130)75:3<368::AID-IJC7>3.0.CO;2-0","article-title":"Rising incidence of biliary tract cancers in Shanghai, China","volume":"75","author":"Hsing","year":"1998","journal-title":"Int. J. Cancer"},{"issue":"5","key":"10.1016\/j.canep.2016.07.021_bib0090","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1080\/13651820802007464","article-title":"Analysis of mortality rates for gallbladder cancer across the world","volume":"10","author":"Hariharan","year":"2008","journal-title":"HPB"},{"issue":"5","key":"10.1016\/j.canep.2016.07.021_bib0095","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1097\/CEJ.0b013e32834653c9","article-title":"Trends in cancer mortality in Mexico, 1981\u20132007","volume":"20","author":"Bosetti","year":"2011","journal-title":"Eur. J. Cancer Prev."},{"issue":"3","key":"10.1016\/j.canep.2016.07.021_bib0100","doi-asserted-by":"crossref","first-page":"231","DOI":"10.12998\/wjcc.v3.i3.231","article-title":"Gall bladder carcinoma: aggressive malignancy with protean loco-regional and distant spread","volume":"3","author":"Dwivedi","year":"2015","journal-title":"World J. Clin. Cases"},{"issue":"6","key":"10.1016\/j.canep.2016.07.021_bib0105","doi-asserted-by":"crossref","first-page":"1131","DOI":"10.1002\/ijc.2910460630","article-title":"Increasing gall\u2212bladder cancer mortality rate during the last decade in Chile, a high\u2212risk area","volume":"46","author":"Chianale","year":"1990","journal-title":"Int. J. Cancer"},{"key":"10.1016\/j.canep.2016.07.021_bib0110","series-title":"Check and Conversion Programs for Cancer Registries (IARC\/IACR Tools for Cancer Registries)","author":"Ferlay","year":"2005"},{"key":"10.1016\/j.canep.2016.07.021_bib0115","series-title":"International Classification of Diseases for Oncology","year":"2013"},{"key":"10.1016\/j.canep.2016.07.021_bib0120","series-title":"International Statistical Classification of Diseases and Health Related Problems (ICD-10)","year":"2004"},{"key":"10.1016\/j.canep.2016.07.021_bib0125","series-title":"Mortality Database","year":"2014"},{"key":"10.1016\/j.canep.2016.07.021_bib0130","series-title":"Trends in Cancer Mortality for Selected Sites in 24 Countries 1950\u20131959","author":"Segi","year":"1963"},{"key":"10.1016\/j.canep.2016.07.021_bib0135","volume":"Vol I","author":"Doll","year":"1966"},{"key":"10.1016\/j.canep.2016.07.021_bib0140","first-page":"1","volume":"Vol. 128","author":"Esteve","year":"1994"},{"key":"10.1016\/j.canep.2016.07.021_bib0145","series-title":"Stata Data Analysis and Statistical Software. Version 12.1","year":"2011"},{"issue":"1","key":"10.1016\/j.canep.2016.07.021_bib0150","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1093\/annonc\/mdn533","article-title":"Epidemiology of biliary tract cancers: an update","volume":"20","author":"Randi","year":"2009","journal-title":"Ann. Oncol."},{"issue":"5","key":"10.1016\/j.canep.2016.07.021_bib0155","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1002\/ijc.2910410503","article-title":"Frequency of gallbladder cancer in chile, a high-risk area","volume":"41","author":"Nervi","year":"1988","journal-title":"Int. J. Cancer"},{"issue":"4","key":"10.1016\/j.canep.2016.07.021_bib0160","first-page":"486","article-title":"Cancer de la vesicula biliar: estudios necesarios para el diseno de estrategias de prevencion y diagnostico precoz","volume":"22","author":"Roa","year":"2011","journal-title":"Rev. Med. Clin. Condes"},{"issue":"9","key":"10.1016\/j.canep.2016.07.021_bib0165","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1038\/nrc1429","article-title":"Gallbladder cancer: lessons from a rare tumour","volume":"4","author":"Wistuba","year":"2004","journal-title":"Nat. Rev. Cancer"},{"issue":"2","key":"10.1016\/j.canep.2016.07.021_bib0170","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1093\/ije\/12.2.156","article-title":"The epidemiology of cancer of the extra-hepatic biliary tract in Bolivia","volume":"12","author":"Rios-Dalenz","year":"1983","journal-title":"Int. J. Epidemiol."},{"issue":"8","key":"10.1016\/j.canep.2016.07.021_bib0175","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1111\/apt.12655","article-title":"Systematic review with meta-analysis: the relationship between chronic Salmonella typhi carrier status and gall-bladder cancer","volume":"39","author":"Nagaraja","year":"2014","journal-title":"Aliment. Pharmacol. Ther."},{"key":"10.1016\/j.canep.2016.07.021_bib0180","series-title":"Salmonella Typhi and Gallbladder Cancer. Bacteria and Cancer","first-page":"117","author":"Ferreccio","year":"2012"},{"issue":"6","key":"10.1016\/j.canep.2016.07.021_bib0185","doi-asserted-by":"crossref","first-page":"1411","DOI":"10.1002\/ijc.23662","article-title":"Geographic variation of gallbladder cancer mortality and risk factors in Chile: a population-based ecologic study","volume":"123","author":"Andia","year":"2008","journal-title":"Int. J. Cancer"},{"issue":"1\u20132","key":"10.1016\/j.canep.2016.07.021_bib0190","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.mrrev.2011.06.002","article-title":"Candidate gene studies in gallbladder cancer: a systematic review and meta-analysis","volume":"728","author":"Srivastava","year":"2011","journal-title":"Mutat. Res."},{"issue":"2","key":"10.1016\/j.canep.2016.07.021_bib0195","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1002\/ijc.2910570203","article-title":"Reproductive history and cancer of the biliary tract in women","volume":"57","author":"Moerman","year":"1994","journal-title":"Int. J. Cancer"},{"issue":"9","key":"10.1016\/j.canep.2016.07.021_bib0200","doi-asserted-by":"crossref","first-page":"1457","DOI":"10.1038\/sj.bjc.6603703","article-title":"Obesity and the risk of gallbladder cancer: a meta-analysis","volume":"96","author":"Larsson","year":"2007","journal-title":"Br. J. Cancer"},{"key":"10.1016\/j.canep.2016.07.021_bib0205","series-title":"Food, Nutrition, Physical Activity, and the Prevention of Cancer: a Global Perspective","year":"2007"},{"issue":"0","key":"10.1016\/j.canep.2016.07.021_bib0210","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.ypmed.2014.03.027","article-title":"Body mass index and biliary tract disease: a systematic review and meta-analysis of prospective studies","volume":"65","author":"Park","year":"2014","journal-title":"Prev. Med."},{"issue":"8","key":"10.1016\/j.canep.2016.07.021_bib0215","doi-asserted-by":"crossref","first-page":"987","DOI":"10.4067\/S0034-98872013000800004","article-title":"Obesidad y cancer en Chile: estimacion de las fracciones atribuibles poblacionales","volume":"141","author":"Garmendia","year":"2013","journal-title":"Rev. Med. Chil."},{"issue":"9945","key":"10.1016\/j.canep.2016.07.021_bib0220","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1016\/S0140-6736(14)60460-8","article-title":"Global, regional, and national prevalence of overweight and obesity in children and adults during 1980\u20132013: a systematic analysis for the Global Burden of Disease Study 2013","volume":"384","author":"Ng","year":"2014","journal-title":"Lancet"},{"issue":"2","key":"10.1016\/j.canep.2016.07.021_bib0225","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1046\/j.1467-789x.2001.00029.x","article-title":"Obesity prevalence and trends in Latin-American countries","volume":"2","author":"Filozof","year":"2001","journal-title":"Obes. Rev."},{"issue":"4","key":"10.1016\/j.canep.2016.07.021_bib0230","doi-asserted-by":"crossref","first-page":"e18776","DOI":"10.1371\/journal.pone.0018776","article-title":"Association between alcohol consumption and cancers in the Chinese population- A systematic review and meta-analysis","volume":"6","author":"Li","year":"2011","journal-title":"PLoS One"},{"issue":"2","key":"10.1016\/j.canep.2016.07.021_bib0235","first-page":"471","article-title":"Mutagenicity and mutagens of the red chili pepper as gallbladder cancer risk factor in Chilean women","volume":"12","author":"Tsuchiya","year":"2011","journal-title":"Asian Pac. J. Cancer Prev."},{"key":"10.1016\/j.canep.2016.07.021_bib0240","series-title":"WHO Classification of Tumours of the Digestive System","author":"Bosman","year":"2010"},{"key":"10.1016\/j.canep.2016.07.021_bib0245","series-title":"Problema De Salud AUGE N\u00b0 26. Colecistectom\u00eda Preventiva Del c\u00e1ncer De Ves\u00edcula En Personas De 35 a 49 a\u00f1os. Gobierno De Chile","year":"2015"},{"issue":"2","key":"10.1016\/j.canep.2016.07.021_bib0250","doi-asserted-by":"crossref","first-page":"158","DOI":"10.4067\/S0034-98872015000200002","article-title":"[Cobertura de la estrategia preventiva de cancer de vesicula biliar en Chile: resultados de la Encuesta Nacional de Salud 2009\u20132010]","volume":"143","author":"Latorre","year":"2015","journal-title":"Rev. Med. Chil."},{"issue":"5","key":"10.1016\/j.canep.2016.07.021_bib0255","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1016\/j.ejca.2008.11.033","article-title":"Evaluation of data quality in the cancer registry: principles and methods Part II. Completeness","volume":"45","author":"Parkin","year":"2009","journal-title":"Eur. J. Cancer"},{"issue":"3","key":"10.1016\/j.canep.2016.07.021_bib0260","doi-asserted-by":"crossref","first-page":"242","DOI":"10.2105\/AJPH.71.3.242","article-title":"Accuracy of cancer death certificates and its effect on cancer mortality statistics","volume":"71","author":"Percy","year":"1981","journal-title":"Am. J. Public Health"},{"issue":"5","key":"10.1016\/j.canep.2016.07.021_bib0265","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1016\/j.ejca.2008.11.032","article-title":"Evaluation of data quality in the cancer registry: principles and methods Part I: Comparability, validity and timeliness","volume":"45","author":"Bray","year":"2009","journal-title":"Eur. J. Cancer"},{"issue":"3","key":"10.1016\/j.canep.2016.07.021_bib0270","article-title":"Counting the dead and what they died from: an assessment of the global status of cause of death data","volume":"83","author":"Mathers","year":"2005","journal-title":"Bull. World Health Organ."}],"container-title":["Cancer Epidemiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1877782116301163?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1877782116301163?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,9,14]],"date-time":"2019-09-14T01:20:51Z","timestamp":1568424051000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1877782116301163"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,9]]},"references-count":54,"alternative-id":["S1877782116301163"],"URL":"https:\/\/doi.org\/10.1016\/j.canep.2016.07.021","relation":{},"ISSN":["1877-7821"],"issn-type":[{"value":"1877-7821","type":"print"}],"subject":[],"published":{"date-parts":[[2016,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Burden of gallbladder cancer in Central and South America","name":"articletitle","label":"Article Title"},{"value":"Cancer Epidemiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.canep.2016.07.021","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}