{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T04:31:11Z","timestamp":1793421071720,"version":"4.5.0"},"reference-count":21,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["114-2314-B-002-190-MY2"],"award-info":[{"award-number":["114-2314-B-002-190-MY2"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cancer Epidemiology"],"published-print":{"date-parts":[[2026,12]]},"DOI":"10.1016\/j.canep.2026.103229","type":"journal-article","created":{"date-parts":[[2026,9,6]],"date-time":"2026-09-06T03:49:43Z","timestamp":1788666583000},"page":"103229","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Low-dose computed tomography lung cancer screening in asymptomatic young adults"],"prefix":"10.1016","volume":"105","author":[{"given":"Yu-Sen","family":"Huang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hao-Wei","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jenny Ling-Yu","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yeun-Chung","family":"Chang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.canep.2026.103229_bib1","doi-asserted-by":"crossref","DOI":"10.1016\/j.canep.2024.102693","article-title":"Global burden of lung cancer in 2022 and projections to 2050: incidence and mortality estimates from GLOBOCAN","volume":"93","author":"Zhou","year":"2024","journal-title":"Cancer Epidemiol."},{"key":"10.1016\/j.canep.2026.103229_bib2","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1056\/NEJMoa1102873","article-title":"Reduced lung-cancer mortality with low-dose computed tomographic screening","volume":"365","author":"National Lung Screening Trial Research Team","year":"2011","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.canep.2026.103229_bib3","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.lungcan.2007.05.009","article-title":"D\u00e9piscan Group, Baseline results of the Depiscan study: a French randomized pilot trial of lung cancer screening comparing low dose CT scan (LDCT) and chest X-ray (CXR)","volume":"58","author":"Blanchon","year":"2007","journal-title":"Lung Cancer (Amsterdam Netherlands)"},{"key":"10.1016\/j.canep.2026.103229_bib4","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/j.lungcan.2007.08.040","article-title":"DANTE Study Group, Lung cancer screening with spiral CT: baseline results of the randomized Dante trial","volume":"59","author":"Infante","year":"2008","journal-title":"Lung Cancer (Amsterdam Netherlands)"},{"key":"10.1016\/j.canep.2026.103229_bib5","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1111\/resp.14316","article-title":"PM2.5 exposure and risk of lung adenocarcinoma in women of Taiwan: a case-control study with density sampling","volume":"27","author":"Yang","year":"2022","journal-title":"Respirology"},{"key":"10.1016\/j.canep.2026.103229_bib6","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/S2213-2600(23)00338-7","article-title":"TALENT Investigators, Low-dose CT screening among never-smokers with or without a family history of lung cancer in Taiwan: a prospective cohort study","volume":"12","author":"Chang","year":"2024","journal-title":"Lancet Respir. Med."},{"key":"10.1016\/j.canep.2026.103229_bib7","article-title":"Taiwan national lung cancer early detection program for heavy smokers and non-smokers with family history of lung cancer","volume":"42","author":"Yang","year":"2024","journal-title":"J. Clin. Oncol."},{"issue":"10","key":"10.1016\/j.canep.2026.103229_bib8","doi-asserted-by":"crossref","first-page":"S71","DOI":"10.1016\/j.jtho.2025.09.131","article-title":"MA05.02 The preliminary results of Taiwan national LDCT lung cancer screening for smokers and nonsmokers with a family history of lung cancer","volume":"20","author":"Yang","year":"2025","journal-title":"J. Thorac. Oncol."},{"key":"10.1016\/j.canep.2026.103229_bib9","doi-asserted-by":"crossref","DOI":"10.1002\/cam4.6914","article-title":"Opportunistic lung cancer screening with low-dose computed tomography in National Cancer Center of China: the first 14\u2009years\u2019 experience","volume":"13","author":"Tang","year":"2024","journal-title":"Cancer Med."},{"key":"10.1016\/j.canep.2026.103229_bib10","doi-asserted-by":"crossref","first-page":"e82","DOI":"10.1016\/j.jtho.2018.12.008","article-title":"Optimal starting age for lung cancer screening with low-dose computed tomography: a population level analysis","volume":"14","author":"Li","year":"2019","journal-title":"J. Thorac. Oncol."},{"key":"10.1016\/j.canep.2026.103229_bib11","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1001\/jamaoncol.2015.4482","article-title":"Association between younger age and targetable genomic alterations and prognosis in non-small-cell lung cancer","volume":"2","author":"Sacher","year":"2016","journal-title":"JAMA Oncol."},{"key":"10.1016\/j.canep.2026.103229_bib12","doi-asserted-by":"crossref","first-page":"2801","DOI":"10.1002\/cncr.33573","article-title":"Germline mutations and age at onset of lung adenocarcinoma","volume":"127","author":"Reckamp","year":"2021","journal-title":"Cancer"},{"key":"10.1016\/j.canep.2026.103229_bib13","doi-asserted-by":"crossref","first-page":"6774","DOI":"10.1038\/s41598-020-63656-7","article-title":"Impact of cooking oil fume exposure and fume extractor use on lung cancer risk in non-smoking Han Chinese women","volume":"10","author":"Chen","year":"2020","journal-title":"Sci. Rep."},{"key":"10.1016\/j.canep.2026.103229_bib14","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1016\/j.jfma.2019.01.012","article-title":"Taiwan\u2019s Nationwide Cancer Registry System of 40 years: past, present, and future","volume":"118","author":"Chiang","year":"2019","journal-title":"J. Formos. Med. Assoc."},{"key":"10.1016\/j.canep.2026.103229_bib15","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1667\/RR15015.1","article-title":"Incidence of breast cancer in the life span study of atomic bomb survivors: 1958\u20132009","volume":"190","author":"Brenner","year":"2018","journal-title":"Radiat. Res."},{"key":"10.1016\/j.canep.2026.103229_bib16","doi-asserted-by":"crossref","first-page":"j347","DOI":"10.1136\/bmj.j347","article-title":"Exposure to low dose computed tomography for lung cancer screening and risk of cancer: secondary analysis of trial data and risk-benefit analysis","volume":"356","author":"Rampinelli","year":"2017","journal-title":"Br. Med. J. (Clin. Res. Ed. )."},{"key":"10.1016\/j.canep.2026.103229_bib17","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1016\/j.jtho.2018.11.002","article-title":"Role of low-dose computerized tomography in lung cancer screening among never-smokers","volume":"14","author":"Kang","year":"2019","journal-title":"J. Thorac. Oncol."},{"key":"10.1016\/j.canep.2026.103229_bib18","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2025.46222","article-title":"Age-based screening for lung cancer surveillance in the US","volume":"8","author":"Yang","year":"2025","journal-title":"JAMA Netw. Open."},{"key":"10.1016\/j.canep.2026.103229_bib19","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1186\/s12943-024-02140-6","article-title":"Artificial intelligence alphafold model for molecular biology and drug discovery: a machine-learning-driven informatics investigation","volume":"23","author":"Guo","year":"2024","journal-title":"Mol. Cancer"},{"key":"10.1016\/j.canep.2026.103229_bib20","doi-asserted-by":"crossref","first-page":"2805","DOI":"10.1097\/JS9.0000000000003668","article-title":"Current concerns and future directions of large language model ChatGPT in medicine: a machine-learning-driven global-scale bibliometric analysis","volume":"112","author":"Guo","year":"2026","journal-title":"Int. J. Surg."},{"key":"10.1016\/j.canep.2026.103229_bib21","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1269\/jrr.33.133","article-title":"Radon concentration in two largest cities in semitropical Taiwan","volume":"33","author":"Chen","year":"1992","journal-title":"J. Radiat. Res."}],"container-title":["Cancer Epidemiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1877782126002456?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1877782126002456?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T04:00:37Z","timestamp":1793419237000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1877782126002456"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,12]]},"references-count":21,"alternative-id":["S1877782126002456"],"URL":"https:\/\/doi.org\/10.1016\/j.canep.2026.103229","relation":{},"ISSN":["1877-7821"],"issn-type":[{"value":"1877-7821","type":"print"}],"subject":[],"published":{"date-parts":[[2026,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Low-dose computed tomography lung cancer screening in asymptomatic young adults","name":"articletitle","label":"Article Title"},{"value":"Cancer Epidemiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.canep.2026.103229","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"103229"}}