{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T04:30:45Z","timestamp":1793421045800,"version":"4.5.0"},"reference-count":33,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100010809","name":"Jascha Foundation","doi-asserted-by":"publisher","award":["2023\\u20130408"],"award-info":[{"award-number":["2023\\u20130408"]}],"id":[{"id":"10.13039\/100010809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008363","name":"Danish Cancer Society","doi-asserted-by":"publisher","award":["Rp21772-A17580"],"award-info":[{"award-number":["Rp21772-A17580"]}],"id":[{"id":"10.13039\/100008363","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cancer Epidemiology"],"published-print":{"date-parts":[[2026,12]]},"DOI":"10.1016\/j.canep.2026.103254","type":"journal-article","created":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T13:13:08Z","timestamp":1791810788000},"page":"103254","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Risk of malignant melanoma in hyperthyroid and hypothyroid female populations: Results from a large Danish cohort study"],"prefix":"10.1016","volume":"105","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4457-9822","authenticated-orcid":false,"given":"Meyya","family":"Bouazzi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8347-1398","authenticated-orcid":false,"given":"Susanne K.","family":"Kjaer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-4100-9119","authenticated-orcid":false,"given":"Mathias Gr\u00f8n","family":"B\u00f6ckel-Lundorff","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jane","family":"Christensen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9443-5977","authenticated-orcid":false,"given":"Jens","family":"Pedersen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-9744-4452","authenticated-orcid":false,"given":"Bugge","family":"N\u00f8hr","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8124-4880","authenticated-orcid":false,"given":"Allan","family":"Jensen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.canep.2026.103254_bib1","doi-asserted-by":"crossref","first-page":"1387","DOI":"10.1002\/j.2040-4603.2016.tb00708.x","article-title":"Hypothalamus-pituitary-thyroid axis","volume":"6","author":"Ortiga-Carvalho","year":"2016","journal-title":"Compr. Physiol."},{"key":"10.1016\/j.canep.2026.103254_bib2","doi-asserted-by":"crossref","DOI":"10.1177\/20420188231158163","article-title":"The role of supporting and disruptive mechanisms of FT3 homeostasis in regulating the hypothalamic-pituitary-thyroid axis","volume":"14","author":"Hoermann","year":"2023","journal-title":"Ther. Adv. Endocrinol. Metab."},{"issue":"10460","key":"10.1016\/j.canep.2026.103254_bib3","doi-asserted-by":"crossref","first-page":"1347","DOI":"10.1016\/S0140-6736(24)01614-3","article-title":"Hypothyroidism","volume":"404","author":"Taylor","year":"2024","journal-title":"Lancet"},{"issue":"9","key":"10.1016\/j.canep.2026.103254_bib4","doi-asserted-by":"crossref","first-page":"1818","DOI":"10.1002\/ijc.70007","article-title":"Risk of breast cancer among women with hypo- and hyperthyroidism: Results from a large nationwide cohort study","volume":"157","author":"Jensen","year":"2025","journal-title":"Int. J. Cancer"},{"issue":"1","key":"10.1016\/j.canep.2026.103254_bib5","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1186\/s12902-024-01670-w","article-title":"The risk of thyroid cancer and sex differences in Hashimoto's thyroiditis, a meta-analysis","volume":"24","author":"Le","year":"2024","journal-title":"BMC Endocr. Disord."},{"issue":"3","key":"10.1016\/j.canep.2026.103254_bib6","doi-asserted-by":"crossref","DOI":"10.3390\/jcm11030687","article-title":"The TSH\/Thyroid Hormones Axis and Breast Cancer","volume":"11","author":"Voutsadakis","year":"2022","journal-title":"J. Clin. Med."},{"issue":"1","key":"10.1016\/j.canep.2026.103254_bib7","article-title":"The effect of thyroid dysfunction on breast cancer risk: an updated meta-analysis","volume":"30","author":"Tran","year":"2023","journal-title":"Eng. ) Endocr. Relat. Cancer"},{"issue":"10","key":"10.1016\/j.canep.2026.103254_bib8","doi-asserted-by":"crossref","first-page":"1035","DOI":"10.1007\/s40618-017-0679-x","article-title":"Does thyroid dysfunction increase the risk of breast cancer? A systematic review and meta-analysis","volume":"40","author":"Fang","year":"2017","journal-title":"J. Endocrinol. Invest."},{"issue":"5","key":"10.1016\/j.canep.2026.103254_bib9","doi-asserted-by":"crossref","first-page":"1545","DOI":"10.1007\/s43032-024-01721-6","article-title":"Effects of thyroid hormones on cellular development in human ovarian granulosa tumor cells (KGN)","volume":"32","author":"Yu","year":"2025","journal-title":"Reprod. Sci."},{"issue":"15","key":"10.1016\/j.canep.2026.103254_bib10","doi-asserted-by":"crossref","first-page":"1977","DOI":"10.1038\/onc.2015.262","article-title":"The thyroid hormone-\u03b1v\u03b23 integrin axis in ovarian cancer: regulation of gene transcription and MAPK-dependent proliferation","volume":"35","author":"Shinderman-Maman","year":"2016","journal-title":"Oncogene"},{"key":"10.1016\/j.canep.2026.103254_bib11","doi-asserted-by":"crossref","DOI":"10.1093\/jnci\/djag055","article-title":"Pre-diagnosis thyroid dysfunction and ovarian cancer risk and survival: a prospective cohort study","author":"Majidi","year":"2026","journal-title":"Eng. J. Natl. Cancer Inst."},{"key":"10.1016\/j.canep.2026.103254_bib12","doi-asserted-by":"crossref","DOI":"10.1158\/1055-9965.EPI-25-1668","article-title":"Risk of epithelial ovarian tumors among women diagnosed with hypo- and hyperthyroidism: Findings from a large nationwide cohort study","author":"Jensen","year":"2026","journal-title":"Cancer Epidemiol. Biomark. Prev."},{"issue":"17","key":"10.1016\/j.canep.2026.103254_bib13","doi-asserted-by":"crossref","DOI":"10.3390\/ijms231710036","article-title":"Is melanoma progression affected by thyroid diseases?","volume":"23","author":"Ulisse","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.canep.2026.103254_bib14","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2023.1239883","article-title":"Thyroid dysfunction and risk of cutaneous malignant melanoma: a bidirectional two-sample Mendelian randomization study","volume":"14","author":"Dong","year":"2023","journal-title":"Front. Endocrinol."},{"issue":"4","key":"10.1016\/j.canep.2026.103254_bib15","doi-asserted-by":"crossref","first-page":"1269","DOI":"10.1677\/erc.1.01239","article-title":"Human melanoma cells express functional receptors for thyroid-stimulating hormone","volume":"13","author":"Ellerhorst","year":"2006","journal-title":"Endocr. Relat. Cancer"},{"issue":"16","key":"10.1016\/j.canep.2026.103254_bib16","doi-asserted-by":"crossref","first-page":"5531","DOI":"10.1158\/1078-0432.CCR-03-0368","article-title":"Expression of thyrotropin-releasing hormone by human melanoma and nevi","volume":"10","author":"Ellerhorst","year":"2004","journal-title":"Clin. Cancer Res."},{"issue":"9","key":"10.1016\/j.canep.2026.103254_bib17","doi-asserted-by":"crossref","first-page":"1397","DOI":"10.1038\/sj.bjc.6605624","article-title":"Cancer risk in patients hospitalised for Graves' disease: a population-based cohort study in Sweden","volume":"102","author":"Shu","year":"2010","journal-title":"Br. J. Cancer"},{"issue":"3","key":"10.1016\/j.canep.2026.103254_bib18","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0122958","article-title":"Association of thyroid diseases with primary extra-thyroidal malignancies in women: results of a cross-sectional study of 6,386 patients","volume":"10","author":"Prinzi","year":"2015","journal-title":"PLoS. One"},{"issue":"3","key":"10.1016\/j.canep.2026.103254_bib19","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1530\/EJE-20-1123","article-title":"Opposing effects of thyroid hormones on cancer risk: a population-based study","volume":"184","author":"Krashin","year":"2021","journal-title":"Eur. J. Endocrinol."},{"issue":"2","key":"10.1016\/j.canep.2026.103254_bib20","doi-asserted-by":"crossref","first-page":"1","DOI":"10.5070\/D33RN7K0D8","article-title":"High prevalence of hypothyroidism in male patients with cutaneous melanoma","volume":"12","author":"Shah","year":"2006","journal-title":"Dermatol. Online J."},{"issue":"5","key":"10.1016\/j.canep.2026.103254_bib21","first-page":"1317","article-title":"High prevalence of hypothyroidism among patients with cutaneous melanoma","volume":"10","author":"Ellerhorst","year":"2003","journal-title":"Oncol. Rep."},{"issue":"12","key":"10.1016\/j.canep.2026.103254_bib22","doi-asserted-by":"crossref","first-page":"1819","DOI":"10.1111\/1346-8138.17945","article-title":"The association between melanoma and autoimmune diseases: a nationwide population-based study in the Republic of Korea","volume":"52","author":"Kim","year":"2025","journal-title":"J. Dermatol."},{"issue":"7","key":"10.1016\/j.canep.2026.103254_bib23","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1177\/1403494810387965","article-title":"The Danish Civil Registration System","volume":"39","author":"Pedersen","year":"2011","journal-title":"Scand. J. Public. Health"},{"issue":"7","key":"10.1016\/j.canep.2026.103254_bib24","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1177\/1403494811401482","article-title":"The Danish National Patient Register","volume":"39","author":"Lynge","year":"2011","journal-title":"Scand. J. Public. Health"},{"key":"10.1016\/j.canep.2026.103254_bib25","doi-asserted-by":"crossref","first-page":"449","DOI":"10.2147\/CLEP.S91125","article-title":"The Danish National Patient Registry: a review of content, data quality, and research potential","volume":"7","author":"Schmidt","year":"2015","journal-title":"Clin. Epidemiol."},{"issue":"7","key":"10.1016\/j.canep.2026.103254_bib26","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1177\/1403494810394717","article-title":"The Danish National Prescription Registry","volume":"39","author":"Kildemoes","year":"2011","journal-title":"Scand. J. Public. Health"},{"issue":"7","key":"10.1016\/j.canep.2026.103254_bib27","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1177\/1403494810393562","article-title":"The Danish Cancer Registry","volume":"39","author":"Gjerstorff","year":"2011","journal-title":"Scand. J. Public. Health"},{"issue":"7","key":"10.1016\/j.canep.2026.103254_bib28","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1177\/1403494810394715","article-title":"Danish Education Registers","volume":"39","author":"Jensen","year":"2011","journal-title":"Scand. J. Public. Health"},{"key":"10.1016\/j.canep.2026.103254_bib29","doi-asserted-by":"crossref","DOI":"10.1155\/2012\/182176","volume":"2012","author":"Takasu","year":"2012","journal-title":"J. Thyroid. Res."},{"issue":"3","key":"10.1016\/j.canep.2026.103254_bib30","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1080\/08916930290031667","article-title":"Postpartum thyroiditis","volume":"35","author":"Lazarus","year":"2002","journal-title":"Autoimmunity"},{"issue":"1-2","key":"10.1016\/j.canep.2026.103254_bib31","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1016\/j.maturitas.2008.09.005","article-title":"The normal menopause transition","volume":"61","author":"McKinlay","year":"2008","journal-title":"Maturitas"},{"issue":"7","key":"10.1016\/j.canep.2026.103254_bib32","doi-asserted-by":"crossref","first-page":"910","DOI":"10.1089\/thy.2018.0539","article-title":"Changes in Prescription Routines for Treating Hypothyroidism Between 2001 and 2015: An Observational Study of 929,684 Primary Care Patients in Copenhagen","volume":"29","author":"Medici","year":"2019","journal-title":"Thyroid"},{"issue":"9","key":"10.1016\/j.canep.2026.103254_bib33","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1016\/j.puhe.2014.07.002","article-title":"High-risk sun-tanning behaviour: a quantitative study in Denmark, 2008-2011","volume":"128","author":"Hansen","year":"2014","journal-title":"Public. Health"}],"container-title":["Cancer Epidemiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1877782126002705?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1877782126002705?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T03:56:31Z","timestamp":1793418991000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1877782126002705"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,12]]},"references-count":33,"alternative-id":["S1877782126002705"],"URL":"https:\/\/doi.org\/10.1016\/j.canep.2026.103254","relation":{},"ISSN":["1877-7821"],"issn-type":[{"value":"1877-7821","type":"print"}],"subject":[],"published":{"date-parts":[[2026,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Risk of malignant melanoma in hyperthyroid and hypothyroid female populations: Results from a large Danish cohort study","name":"articletitle","label":"Article Title"},{"value":"Cancer Epidemiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.canep.2026.103254","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"103254"}}