{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T01:37:21Z","timestamp":1793756241825,"version":"4.6.1"},"reference-count":75,"publisher":"Elsevier BV","issue":"2","content-domain":{"domain":["cancerletters.info","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cancer Letters"],"published-print":{"date-parts":[[2014,4]]},"DOI":"10.1016\/j.canlet.2013.08.016","type":"journal-article","created":{"date-parts":[[2013,8,24]],"date-time":"2013-08-24T16:16:48Z","timestamp":1377361008000},"page":"196-202","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":725,"title":["Helicobacter pylori-induced gastric inflammation and gastric cancer"],"prefix":"10.1016","volume":"345","author":[{"given":"Fei","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenbo","family":"Meng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bingyuan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liang","family":"Qiao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.canlet.2013.08.016_b0005","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1038\/nature05562","article-title":"An African origin for the intimate association between humans and Helicobacter pylori","volume":"445","author":"Linz","year":"2007","journal-title":"Nature"},{"key":"10.1016\/j.canlet.2013.08.016_b0010","doi-asserted-by":"crossref","first-page":"1311","DOI":"10.1016\/S0140-6736(84)91816-6","article-title":"Unidentified curved bacilli in the stomach of patients with gastritis and peptic ulceration","volume":"1","author":"Marshall","year":"1984","journal-title":"Lancet"},{"key":"10.1016\/j.canlet.2013.08.016_b0015","doi-asserted-by":"crossref","first-page":"74","DOI":"10.3322\/canjclin.55.2.74","article-title":"Global cancer statistics 2002","volume":"55","author":"Parkin","year":"2005","journal-title":"CA Cancer J. Clin."},{"key":"10.1016\/j.canlet.2013.08.016_b0020","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1016\/j.giec.2011.07.011","article-title":"The prevalence and incidence of Helicobacter pylori-associated peptic ulcer disease and upper gastrointestinal bleeding throughout the world","volume":"21","author":"Wang","year":"2011","journal-title":"Gastrointest. Endosc. Clin. N. Am."},{"key":"10.1016\/j.canlet.2013.08.016_b0025","first-page":"662","article-title":"Seroprevalence of Helicobacter pylori infection in adults in the Bahamas","volume":"60","author":"Carter","year":"2011","journal-title":"West Indian Med. J."},{"key":"10.1016\/j.canlet.2013.08.016_b0030","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1016\/S0889-8553(05)70139-4","article-title":"Gastric pathology associated with Helicobacter pylori","volume":"29","author":"Warren","year":"2000","journal-title":"Gastroenterol. Clin. North Am."},{"key":"10.1016\/j.canlet.2013.08.016_b0035","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1007\/978-1-62703-005-2_2","article-title":"Helicobacter pylori: an overview","volume":"921","author":"Noto","year":"2012","journal-title":"Methods Mol. Biol."},{"key":"10.1016\/j.canlet.2013.08.016_b0040","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.ajg.2012.06.002","article-title":"Gastric cancer and Helicobacter pylori infection in the Eastern Libya: a descriptive epidemiological study","volume":"13","author":"Elzouki","year":"2012","journal-title":"Arab J. Gastroenterol."},{"key":"10.1016\/j.canlet.2013.08.016_b0045","doi-asserted-by":"crossref","first-page":"\u2217\u22171445","DOI":"10.1093\/jnci\/djj393","article-title":"Opposing risks of gastric cardia and noncardia gastric adenocarcinomas associated with Helicobacter pylori seropositivity","volume":"98","author":"Kamangar","year":"2006","journal-title":"J. Natl. Cancer Inst."},{"key":"10.1016\/j.canlet.2013.08.016_b0050","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1159\/000336352","article-title":"Relationship between gastroesophageal junction adenocarcinoma and Helicobacter pylori infection in Japan","volume":"85","author":"Kamada","year":"2012","journal-title":"Digestion"},{"key":"10.1016\/j.canlet.2013.08.016_b0055","doi-asserted-by":"crossref","first-page":"398","DOI":"10.4321\/S1130-01082007000700006","article-title":"Prevalence of Helicobacter pylori infection in gastric MALT lymphoma: a systematic review","volume":"99","author":"Asenjo","year":"2007","journal-title":"Rev. Esp. Enferm. Dig."},{"key":"10.1016\/j.canlet.2013.08.016_b0060","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1128\/CMR.00054-05","article-title":"Pathogenesis of Helicobacter pylori infection","volume":"19","author":"Kusters","year":"2006","journal-title":"Clin. Microbiol. Rev."},{"key":"10.1016\/j.canlet.2013.08.016_b0065","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.cgh.2009.07.017","article-title":"Effects of Helicobacter pylori eradication on early stage gastric mucosa-associated lymphoid tissue lymphoma","volume":"8","author":"Zullo","year":"2010","journal-title":"Clin. Gastroenterol. Hepatol."},{"key":"10.1016\/j.canlet.2013.08.016_b0070","doi-asserted-by":"crossref","first-page":"936","DOI":"10.1053\/j.gastro.2012.06.035","article-title":"Second cancers and residual disease in patients treated for gastric mucosa-associated lymphoid tissue lymphoma by Helicobacter pylori eradication and followed for 10years","volume":"143","author":"W\u00fcndisch","year":"2012","journal-title":"Gastroenterology"},{"key":"10.1016\/j.canlet.2013.08.016_b0075","doi-asserted-by":"crossref","first-page":"1192","DOI":"10.1172\/JCI61578","article-title":"Multistep activation of the Helicobacter pylori effector CagA","volume":"122","author":"Muller","year":"2012","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.canlet.2013.08.016_b0080","doi-asserted-by":"crossref","first-page":"e1000684","DOI":"10.1371\/journal.ppat.1000684","article-title":"Helicobacter pylori type iv secretion apparatus exploits \u03b21 integrin in a novel RGD-independent manner","volume":"5","author":"Van Nhieu","year":"2009","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.canlet.2013.08.016_b0085","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1258\/ebm.2011.011199","article-title":"Helicobacter pylori CagA induces ornithine decarboxylase upregulation via Src\/MEK\/ERK\/c-Myc pathway: implication for progression of gastric diseases","volume":"237","author":"Xu","year":"2012","journal-title":"Exp. Biol. Med."},{"key":"10.1016\/j.canlet.2013.08.016_b0090","doi-asserted-by":"crossref","first-page":"1553","DOI":"10.1172\/JCI61143","article-title":"C-Src and c-Abl kinases control hierarchic phosphorylation and function of the CagA effector protein in Western and East Asian Helicobacter pylori strains","volume":"122","author":"Mueller","year":"2012","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.canlet.2013.08.016_b0095","doi-asserted-by":"crossref","first-page":"e30786","DOI":"10.1371\/journal.pone.0030786","article-title":"Helicobacter pylori CagA triggers expression of the bactericidal lectin REG3\u03b3 via gastric STAT3 activation","volume":"7","author":"Hold","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.canlet.2013.08.016_b0100","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1016\/S1097-2765(02)00681-0","article-title":"Grb2 is a key mediator of Helicobacter pylori CagA protein activities","volume":"10","author":"Mimuro","year":"2002","journal-title":"Mol. Cell."},{"key":"10.1016\/j.canlet.2013.08.016_b0105","doi-asserted-by":"crossref","first-page":"4617","DOI":"10.1038\/sj.onc.1210251","article-title":"Helicobacter pylori CagA interacts with E-cadherin and deregulates the \u03b2-catenin signal that promotes intestinal transdifferentiation in gastric epithelial cells","volume":"26","author":"Murata-Kamiya","year":"2007","journal-title":"Oncogene"},{"key":"10.1016\/j.canlet.2013.08.016_b0110","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1128\/CMR.00011-10","article-title":"Helicobacter pylori and gastric cancer: factors that modulate disease risk","volume":"23","author":"Wroblewski","year":"2010","journal-title":"Clin. Microbiol Rev."},{"key":"10.1016\/j.canlet.2013.08.016_b0115","doi-asserted-by":"crossref","first-page":"14640","DOI":"10.1073\/pnas.1206098109","article-title":"Structural insights into Helicobacter pylori oncoprotein CagA interaction with beta1 integrin","volume":"109","author":"Kaplan-Turkoz","year":"2012","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.canlet.2013.08.016_b0120","doi-asserted-by":"crossref","first-page":"9238","DOI":"10.1073\/pnas.1106200108","article-title":"Helicobacter pylori cytotoxin-associated gene A (CagA) subverts the apoptosis-stimulating protein of p53 (ASPP2) tumor suppressor pathway of the host","volume":"108","author":"Buti","year":"2011","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.canlet.2013.08.016_b0125","doi-asserted-by":"crossref","first-page":"5643","DOI":"10.1038\/onc.2010.304","article-title":"Helicobacter pylori CagA targets gastric tumor suppressor RUNX3 for proteasome-mediated degradation","volume":"29","author":"Tsang","year":"2010","journal-title":"Oncogene"},{"key":"10.1016\/j.canlet.2013.08.016_b0130","doi-asserted-by":"crossref","first-page":"1242","DOI":"10.1038\/embor.2009.210","article-title":"Helicobacter pylori CagA activates NF-\u03baB by targeting TAK1 for TRAF6-mediated Lys 63 ubiquitination","volume":"10","author":"Lamb","year":"2009","journal-title":"EMBO Rep."},{"key":"10.1016\/j.canlet.2013.08.016_b0135","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/j.tim.2012.01.008","article-title":"Intoxication strategy of Helicobacter pylori VacA toxin","volume":"20","author":"Boquet","year":"2012","journal-title":"Trends Microbiol."},{"key":"10.1016\/j.canlet.2013.08.016_b0140","doi-asserted-by":"crossref","first-page":"1026","DOI":"10.1016\/j.micinf.2012.07.002","article-title":"Helicobacter pylori VacA: a new perspective on an invasive chloride channel","volume":"14","author":"Rassow","year":"2012","journal-title":"Microbes Infect."},{"key":"10.1016\/j.canlet.2013.08.016_b0145","doi-asserted-by":"crossref","first-page":"16032","DOI":"10.1073\/pnas.1105175108","article-title":"Helicobacter pylori vacuolating cytotoxin A (VacA) engages the mitochondrial fission machinery to induce host cell death","volume":"108","author":"Jain","year":"2011","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.canlet.2013.08.016_b0150","doi-asserted-by":"crossref","first-page":"92","DOI":"10.3389\/fcimb.2012.00092","article-title":"Vacuolating cytotoxin A (VacA), a key toxin for Helicobacter pylori pathogenesis","volume":"2","author":"Palframan","year":"2012","journal-title":"Front. Cell Infect. Microbiol."},{"key":"10.1016\/j.canlet.2013.08.016_b0155","doi-asserted-by":"crossref","first-page":"1160","DOI":"10.1053\/j.gastro.2012.01.043","article-title":"Vacuolating Cytotoxin and Variants in Atg16L1 that disrupt autophagy promote Helicobacter pylori infection in humans","volume":"142","author":"Raju","year":"2012","journal-title":"Gastroenterology"},{"key":"10.1016\/j.canlet.2013.08.016_b0160","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1002\/jcb.24389","article-title":"Role of the Helicobacter pylori-induced inflammatory response in the development of gastric cancer","volume":"114","author":"Lamb","year":"2013","journal-title":"J. Cell Biochem."},{"key":"10.1016\/j.canlet.2013.08.016_b0165","doi-asserted-by":"crossref","first-page":"9300","DOI":"10.1073\/pnas.0409873102","article-title":"NF-B activation and potentiation of proinflammatory responses by the Helicobacter pylori CagA protein","volume":"102","author":"Brandt","year":"2005","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.canlet.2013.08.016_b0170","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.chom.2012.05.010","article-title":"Tertiary structure-function analysis reveals the pathogenic signaling potentiation mechanism of Helicobacter pylori oncogenic effector CagA","volume":"12","author":"Hayashi","year":"2012","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.canlet.2013.08.016_b0175","doi-asserted-by":"crossref","first-page":"109","DOI":"10.4161\/gmic.1.2.11587","article-title":"The many roads traveled by Helicobacter pylori to NFkappaB activation","volume":"1","author":"Lamb","year":"2010","journal-title":"Gut Microbes"},{"key":"10.1016\/j.canlet.2013.08.016_b0180","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1186\/1471-2180-9-36","article-title":"NF-\u03baB activation by Helicobacter pylori requires Akt-mediated phosphorylation of p65","volume":"9","author":"Takeshima","year":"2009","journal-title":"BMC Microbiol."},{"key":"10.1016\/j.canlet.2013.08.016_b0185","doi-asserted-by":"crossref","first-page":"7162","DOI":"10.4049\/jimmunol.175.11.7162","article-title":"Helicobacter pylori activates NF-kappaB via the alternative pathway in B lymphocytes","volume":"175","author":"Ohmae","year":"2005","journal-title":"J. Immunol."},{"key":"10.1016\/j.canlet.2013.08.016_b0190","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1038\/cr.2010.177","article-title":"Non-canonical NF-kappaB signaling pathway","volume":"21","author":"Sun","year":"2011","journal-title":"Cell Res."},{"key":"10.1016\/j.canlet.2013.08.016_b0195","doi-asserted-by":"crossref","first-page":"5975","DOI":"10.2174\/092986712804485836","article-title":"Stem cells, self-renewal and cancer of the gastric epithelium","volume":"19","author":"Hoffmann","year":"2012","journal-title":"Curr. Med. Chem."},{"key":"10.1016\/j.canlet.2013.08.016_b0200","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1016\/j.prp.2011.09.006","article-title":"Molecular pathology of gastric cancer: research and practice","volume":"207","author":"Yasui","year":"2011","journal-title":"Pathol. Res. Pract."},{"key":"10.1016\/j.canlet.2013.08.016_b0205","first-page":"781","article-title":"Cancer stem cells: the \u2018heartbeat\u2019 of gastric cancer","volume":"7","author":"Xu","year":"2012","journal-title":"J. Gastroenterol."},{"key":"10.1016\/j.canlet.2013.08.016_b0210","doi-asserted-by":"crossref","first-page":"e29007","DOI":"10.1371\/journal.pone.0029007","article-title":"Helicobacter pylori infection of gastrointestinal epithelial cells in vitro induces mesenchymal stem cell migration through an NF-kappaB-dependent pathway","volume":"6","author":"Ferrand","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.canlet.2013.08.016_b0215","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1053\/j.gastro.2011.10.036","article-title":"Helicobacter pylori infection recruits bone marrow-derived cells that participate in gastric preneoplasia in mice","volume":"142","author":"Varon","year":"2012","journal-title":"Gastroenterology"},{"key":"10.1016\/j.canlet.2013.08.016_b0220","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1179\/174329211X12968219310756","article-title":"Redox biology and gastric carcinogenesis: the role of Helicobacter pylori","volume":"16","author":"Handa","year":"2011","journal-title":"Redox Rep."},{"key":"10.1016\/j.canlet.2013.08.016_b0225","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.1053\/j.gastro.2010.06.018","article-title":"Regulation of p53 tumor suppressor by Helicobacter pylori in gastric epithelial cells","volume":"139","author":"Wei","year":"2010","journal-title":"Gastroenterology"},{"key":"10.1016\/j.canlet.2013.08.016_b0230","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1016\/j.chom.2012.10.014","article-title":"Reactive oxygen species-induced autophagic degradation of Helicobacter pylori CagA is specifically suppressed in cancer stem-like cells","volume":"12","author":"Tsugawa","year":"2012","journal-title":"Cell Host Microbe."},{"key":"10.1016\/j.canlet.2013.08.016_b0235","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1007\/s00726-011-1038-4","article-title":"Arginine and polyamines in Helicobacter pylori-induced immune dysregulation and gastric carcinogenesis","volume":"42","author":"Chaturvedi","year":"2011","journal-title":"Amino Acids"},{"key":"10.1016\/j.canlet.2013.08.016_b0240","doi-asserted-by":"crossref","first-page":"1696","DOI":"10.1053\/j.gastro.2011.07.045","article-title":"Spermine oxidase mediates the gastric cancer risk associated with Helicobacter pylori CagA","volume":"141","author":"Chaturvedi","year":"2011","journal-title":"Gastroenterology"},{"key":"10.1016\/j.canlet.2013.08.016_b0245","doi-asserted-by":"crossref","first-page":"687359","DOI":"10.1155\/2012\/687359","article-title":"P53 family: role of protein isoforms in human cancer","volume":"2012","author":"Wei","year":"2012","journal-title":"J. Nucleic Acids"},{"key":"10.1016\/j.canlet.2013.08.016_b0250","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/j.virol.2008.09.034","article-title":"The common mechanisms of transformation by the small DNA tumor viruses: the inactivation of tumor suppressor gene products: p53","volume":"384","author":"Levine","year":"2009","journal-title":"Virology"},{"key":"10.1016\/j.canlet.2013.08.016_b0255","doi-asserted-by":"crossref","first-page":"8521","DOI":"10.1158\/0008-5472.CAN-04-3511","article-title":"Spermine oxidation induced by Helicobacter pylori results in apoptosis and DNA damage: implications for gastric carcinogenesis","volume":"64","author":"Xu","year":"2004","journal-title":"Cancer Res."},{"key":"10.1016\/j.canlet.2013.08.016_b0260","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1111\/j.1462-5822.2008.01237.x","article-title":"Helicobacter pylori activate epidermal growth factor receptor- and phosphatidylinositol 3-OH kinase-dependent Akt and glycogen synthase kinase 3\u03b2 phosphorylation","volume":"11","author":"Tabassam","year":"2009","journal-title":"Cell Microbiol."},{"key":"10.1016\/j.canlet.2013.08.016_b0265","doi-asserted-by":"crossref","first-page":"196","DOI":"10.3164\/jcbn.08-254","article-title":"The expression of Murine Double Minute 2 (MDM2) on Helicobacter pylori-infected intestinal metaplasia and gastric cancer","volume":"44","author":"Nakajima","year":"2009","journal-title":"J. Clin. Biochem. Nutr."},{"key":"10.1016\/j.canlet.2013.08.016_b0270","doi-asserted-by":"crossref","first-page":"1135","DOI":"10.1038\/ncb1928","article-title":"P53 isoforms \u0394133p53 and p53\u03b2 are endogenous regulators of replicative cellular senescence","volume":"11","author":"Fujita","year":"2009","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.canlet.2013.08.016_b0275","doi-asserted-by":"crossref","first-page":"E2543","DOI":"10.1073\/pnas.1205664109","article-title":"PNAS Plus: pathogenic bacterium Helicobacter pylori alters the expression profile of p53 protein isoforms and p53 response to cellular stresses","volume":"109","author":"Wei","year":"2012","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.canlet.2013.08.016_b0280","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1111\/j.1349-7006.2009.01434.x","article-title":"Aberrant DNA methylation in contrast with mutations","volume":"101","author":"Ushijima","year":"2010","journal-title":"Cancer Sci."},{"key":"10.1016\/j.canlet.2013.08.016_b0285","first-page":"1271","article-title":"Promoter methylation of tumor-related genes in gastric carcinogenesis","volume":"27","author":"Zhao","year":"2012","journal-title":"Histol. Histopathol."},{"key":"10.1016\/j.canlet.2013.08.016_b0290","doi-asserted-by":"crossref","first-page":"1836","DOI":"10.1053\/j.gastro.2009.12.042","article-title":"CpG methylation and reduced expression of O6-methylguanine DNA methyltransferase is associated with Helicobacter pylori infection","volume":"138","author":"Sepulveda","year":"2010","journal-title":"Gastroenterology"},{"key":"10.1016\/j.canlet.2013.08.016_b0295","doi-asserted-by":"crossref","first-page":"5129","DOI":"10.3748\/wjg.v18.i36.5129","article-title":"CpG island methylator phenotype and Helicobacter pylori infection associated with gastric cancer","volume":"18","author":"Liu","year":"2012","journal-title":"World J. Gastroenterol."},{"key":"10.1016\/j.canlet.2013.08.016_b0300","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1053\/j.gastro.2012.10.002","article-title":"Helicobacter pylori causes epigenetic dysregulation of FOXD3 to promote gastric carcinogenesis","volume":"144","author":"Cheng","year":"2013","journal-title":"Gastroenterology"},{"key":"10.1016\/j.canlet.2013.08.016_b0305","doi-asserted-by":"crossref","first-page":"5507","DOI":"10.1002\/cncr.27604","article-title":"Stepwise cumulation of RUNX3 methylation mediated by Helicobacter pylori infection contributes to gastric carcinoma progression","volume":"118","author":"Lu","year":"2012","journal-title":"Cancer"},{"key":"10.1016\/j.canlet.2013.08.016_b0310","doi-asserted-by":"crossref","first-page":"3094","DOI":"10.1128\/IAI.00232-12","article-title":"Analysis of Helicobacter pylori cagA promoter elements required for salt-induced upregulation of CagA expression","volume":"80","author":"Loh","year":"2012","journal-title":"Infect. Immun."},{"key":"10.1016\/j.canlet.2013.08.016_b0315","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1159\/000336919","article-title":"Macro-role of MicroRNA in gastric cancer","volume":"30","author":"Link","year":"2012","journal-title":"Dig. Dis."},{"key":"10.1016\/j.canlet.2013.08.016_b0320","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1007\/s10875-011-9626-3","article-title":"Interweaving MicroRNAs and proinflammatory cytokines in gastric mucosa with reference to H. pylori infection","volume":"32","author":"Isomoto","year":"2012","journal-title":"J. Clin. Immunol."},{"key":"10.1016\/j.canlet.2013.08.016_b0325","article-title":"CagA mediates epigenetic regulation to attenuate let-7 expression in Helicobacter pylori-related carcinogenesis","author":"Hayashi","year":"2012","journal-title":"Gut"},{"key":"10.1016\/j.canlet.2013.08.016_b0330","doi-asserted-by":"crossref","first-page":"1430","DOI":"10.1158\/0008-5472.CAN-09-2755","article-title":"Inflammatory processes triggered by Helicobacter pylori infection cause aberrant DNA methylation in gastric epithelial cells","volume":"70","author":"Niwa","year":"2010","journal-title":"Cancer Res."},{"key":"10.1016\/j.canlet.2013.08.016_b0335","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1093\/carcin\/bgq219","article-title":"Insufficient role of cell proliferation in aberrant DNA methylation induction and involvement of specific types of inflammation","volume":"32","author":"Hur","year":"2011","journal-title":"Carcinogenesis"},{"key":"10.1016\/j.canlet.2013.08.016_b0340","doi-asserted-by":"crossref","first-page":"2550","DOI":"10.2741\/4070","article-title":"Association between obesity and gallbladder cancer","volume":"17","author":"Wang","year":"2012","journal-title":"Front Biosci."},{"key":"10.1016\/j.canlet.2013.08.016_b0345","doi-asserted-by":"crossref","first-page":"2356","DOI":"10.2741\/4057","article-title":"Obesity-related hepatocellular carcinoma: roles of risk factors altered in obesity","volume":"17","author":"Shen","year":"2012","journal-title":"Front. Biosci."},{"key":"10.1016\/j.canlet.2013.08.016_b0350","doi-asserted-by":"crossref","first-page":"2383","DOI":"10.2741\/4059","article-title":"Obesity and gastric cancer","volume":"17","author":"Li","year":"2012","journal-title":"Front. Biosci."},{"key":"10.1016\/j.canlet.2013.08.016_b0355","doi-asserted-by":"crossref","first-page":"165","DOI":"10.4103\/1319-3767.80377","article-title":"Helicobacter pylori infection and its relationship to metabolic syndrome: is it a myth or fact?","volume":"17","author":"Albaker","year":"2011","journal-title":"Saudi J. Gastroenterol."},{"key":"10.1016\/j.canlet.2013.08.016_b0360","first-page":"226","article-title":"Seroprevalence of Helicobacter pylori infection in large series of patients in an urban area of Saudi Arabia","volume":"52","author":"Marie","year":"2008","journal-title":"Korean J. Gastroenterol."},{"key":"10.1016\/j.canlet.2013.08.016_b0365","doi-asserted-by":"crossref","first-page":"2646","DOI":"10.1007\/s10620-007-0185-7","article-title":"Helicobacter pylori prevalence in diabetes mellitus patients with dyspeptic symptoms and its relationship to glycemic control and late complications","volume":"53","author":"Demir","year":"2008","journal-title":"Dig. Dis. Sci."},{"key":"10.1016\/j.canlet.2013.08.016_b0370","doi-asserted-by":"crossref","first-page":"1234","DOI":"10.1053\/j.gastro.2008.12.045","article-title":"Hyperglycemia increases risk of gastric cancer posed by Helicobacter pylori infection: a population-based cohort study","volume":"136","author":"Ikeda","year":"2009","journal-title":"Gastroenterology"},{"key":"10.1016\/j.canlet.2013.08.016_b0375","doi-asserted-by":"crossref","first-page":"2258","DOI":"10.1128\/IAI.01271-12","article-title":"High dietary salt intake exacerbates Helicobacter pylori-induced gastric carcinogenesis","volume":"81","author":"Gaddy","year":"2013","journal-title":"Infect. Immun."}],"container-title":["Cancer Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304383513005910?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304383513005910?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,10,13]],"date-time":"2018-10-13T14:52:38Z","timestamp":1539442358000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0304383513005910"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,4]]},"references-count":75,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2014,4]]}},"alternative-id":["S0304383513005910"],"URL":"https:\/\/doi.org\/10.1016\/j.canlet.2013.08.016","relation":{},"ISSN":["0304-3835"],"issn-type":[{"value":"0304-3835","type":"print"}],"subject":[],"published":{"date-parts":[[2014,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Helicobacter pylori-induced gastric inflammation and gastric cancer","name":"articletitle","label":"Article Title"},{"value":"Cancer Letters","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.canlet.2013.08.016","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Elsevier Ireland Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}