{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T21:54:10Z","timestamp":1791410050088,"version":"4.3.3"},"reference-count":55,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2015,2,1]],"date-time":"2015-02-01T00:00:00Z","timestamp":1422748800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100006727","name":"University of Kansas Medical Center","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100006727","id-type":"DOI","asserted-by":"crossref"}]},{"name":"University of Kansas Cancer Center","award":["1-P30-CA168524-02"],"award-info":[{"award-number":["1-P30-CA168524-02"]}]}],"content-domain":{"domain":["cancerletters.info","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cancer Letters"],"published-print":{"date-parts":[[2015,2]]},"DOI":"10.1016\/j.canlet.2014.12.011","type":"journal-article","created":{"date-parts":[[2014,12,12]],"date-time":"2014-12-12T18:07:28Z","timestamp":1418407648000},"page":"448-453","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":91,"title":["Tumor matrix protein collagen XI\u03b11 in cancer"],"prefix":"10.1016","volume":"357","author":[{"given":"Zoe","family":"Raglow","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5370-0842","authenticated-orcid":false,"given":"Sufi M.","family":"Thomas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.canlet.2014.12.011_bib0010","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.1016\/j.ejca.2010.02.027","article-title":"Extracellular matrix: a gatekeeper in the transition from dormancy to metastatic growth","volume":"46","author":"Barkan","year":"2010","journal-title":"Eur. J. Cancer"},{"key":"10.1016\/j.canlet.2014.12.011_bib0015","doi-asserted-by":"crossref","first-page":"1216","DOI":"10.1126\/science.1176009","article-title":"The extracellular matrix: not just pretty fibrils","volume":"326","author":"Hynes","year":"2009","journal-title":"Science"},{"key":"10.1016\/j.canlet.2014.12.011_bib0020","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1016\/j.cell.2009.10.027","article-title":"Matrix crosslinking forces tumor progression by enhancing integrin signaling","volume":"139","author":"Levental","year":"2009","journal-title":"Cell"},{"key":"10.1016\/j.canlet.2014.12.011_bib0025","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1016\/S0006-3495(00)76279-5","article-title":"Cell movement is guided by the rigidity of the substrate","volume":"79","author":"Lo","year":"2000","journal-title":"Biophys. J."},{"key":"10.1016\/j.canlet.2014.12.011_bib0030","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/j.ccr.2005.08.010","article-title":"Tensional homeostasis and the malignant phenotype","volume":"8","author":"Paszek","year":"2005","journal-title":"Cancer Cell"},{"key":"10.1016\/j.canlet.2014.12.011_bib0035","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/j.ccr.2011.01.020","article-title":"Bone marrow-derived myofibroblasts contribute to the mesenchymal stem cell niche and promote tumor growth","volume":"19","author":"Quante","year":"2011","journal-title":"Cancer Cell"},{"key":"10.1016\/j.canlet.2014.12.011_bib0040","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/j.cell.2005.02.034","article-title":"Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1\/CXCL12 secretion","volume":"121","author":"Orimo","year":"2005","journal-title":"Cell"},{"key":"10.1016\/j.canlet.2014.12.011_bib0045","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1097\/MOP.0b013e32832185c5","article-title":"Genetic and orthopedic aspects of collagen disorders","volume":"21","author":"Carter","year":"2009","journal-title":"Curr. Opin. Pediatr"},{"key":"10.1016\/j.canlet.2014.12.011_bib0050","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.matbio.2012.11.001","article-title":"Collagen XVI in health and disease","volume":"32","author":"Grassel","year":"2013","journal-title":"Matrix Biol"},{"key":"10.1016\/j.canlet.2014.12.011_bib0055","doi-asserted-by":"crossref","first-page":"a004978","DOI":"10.1101\/cshperspect.a004978","article-title":"The collagen family","volume":"3","author":"Ricard-Blum","year":"2011","journal-title":"Cold Spring Harb. Perspect. Biol"},{"key":"10.1016\/j.canlet.2014.12.011_bib0060","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1002\/aja.1002040106","article-title":"Developmental pattern of expression of the mouse alpha 1 (XI) collagen gene (Col11a1)","volume":"204","author":"Yoshioka","year":"1995","journal-title":"Dev. Dyn"},{"key":"10.1016\/j.canlet.2014.12.011_bib0065","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1007\/s11626-013-9692-3","article-title":"Nuclear factor Y (NF-Y) regulates the proximal promoter activity of the mouse collagen alpha1(XI) gene (Col11a1) in chondrocytes","volume":"50","author":"Hida","year":"2014","journal-title":"In Vitro Cell. Dev. Biol. Anim"},{"key":"10.1016\/j.canlet.2014.12.011_bib0070","first-page":"296","article-title":"The general pediatrician and the craniofacial defects team","volume":"65","author":"Domet","year":"1986","journal-title":"Ear Nose Throat J."},{"key":"10.1016\/j.canlet.2014.12.011_bib0075","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1186\/1471-2350-14-48","article-title":"Deletions within COL11A1 in Type 2 stickler syndrome detected by multiplex ligation-dependent probe amplification (MLPA)","volume":"14","author":"Vijzelaar","year":"2013","journal-title":"BMC Med. Genet"},{"key":"10.1016\/j.canlet.2014.12.011_bib0080","doi-asserted-by":"crossref","first-page":"663","DOI":"10.3109\/01443615.2013.817977","article-title":"Fibrochondrogenesis: prenatal diagnosis and outcome","volume":"33","author":"Bekdache","year":"2013","journal-title":"J. Obstet. Gynaecol"},{"key":"10.1016\/j.canlet.2014.12.011_bib0085","doi-asserted-by":"crossref","first-page":"940","DOI":"10.1002\/art.38300","article-title":"Assessment of osteoarthritis candidate genes in a meta-analysis of nine genome-wide association studies","volume":"66","author":"Rodriguez-Fontenla","year":"2014","journal-title":"Arthritis Rheumatol"},{"key":"10.1016\/j.canlet.2014.12.011_bib0090","doi-asserted-by":"crossref","first-page":"1271","DOI":"10.1086\/522377","article-title":"A functional polymorphism in COL11A1, which encodes the alpha 1 chain of type XI collagen, is associated with susceptibility to lumbar disc herniation","volume":"81","author":"Mio","year":"2007","journal-title":"Am. J. Hum. Genet"},{"key":"10.1016\/j.canlet.2014.12.011_bib0095","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1055\/s-0031-1299752","article-title":"COL11A1 gene is associated with limbus vertebra in gymnasts","volume":"33","author":"Koyama","year":"2012","journal-title":"Int. J. Sports Med"},{"key":"10.1016\/j.canlet.2014.12.011_bib0100","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1136\/bjsports-2013-092379","article-title":"Association of type XI collagen genes with chronic Achilles tendinopathy in independent populations from South Africa and Australia","volume":"47","author":"Hay","year":"2013","journal-title":"Br. J. Sports Med"},{"key":"10.1016\/j.canlet.2014.12.011_bib0105","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1093\/carcin\/22.6.875","article-title":"Colorectal carcinogenesis is associated with stromal expression of COL11A1 and COL5A2","volume":"22","author":"Fischer","year":"2001","journal-title":"Carcinogenesis"},{"key":"10.1016\/j.canlet.2014.12.011_bib0110","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1186\/1471-2407-1-17","article-title":"COL11A1 in FAP polyps and in sporadic colorectal tumors","volume":"1","author":"Fischer","year":"2001","journal-title":"BMC Cancer"},{"key":"10.1016\/j.canlet.2014.12.011_bib0115","doi-asserted-by":"crossref","first-page":"8749","DOI":"10.1074\/jbc.275.12.8749","article-title":"The pro-alpha3(V) collagen chain. Complete primary structure, expression domains in adult and developing tissues, and comparison to the structures and expression domains of the other types V and XI procollagen chains","volume":"275","author":"Imamura","year":"2000","journal-title":"J. Biol. Chem"},{"key":"10.1016\/j.canlet.2014.12.011_bib0120","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1186\/1755-8794-3-51","article-title":"Multi-cancer computational analysis reveals invasion-associated variant of desmoplastic reaction involving INHBA, THBS2 and COL11A1","volume":"3","author":"Kim","year":"2010","journal-title":"BMC Med Genomics"},{"key":"10.1016\/j.canlet.2014.12.011_bib0125","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1186\/1471-2407-11-529","article-title":"Human cancer cells express Slug-based epithelial-mesenchymal transition gene expression signature obtained in vivo","volume":"11","author":"Anastassiou","year":"2011","journal-title":"BMC Cancer"},{"key":"10.1016\/j.canlet.2014.12.011_bib0130","doi-asserted-by":"crossref","first-page":"19647","DOI":"10.1074\/jbc.M109.088153","article-title":"Microarray-based transcriptional and epigenetic profiling of matrix metalloproteinases, collagens, and related genes in cancer","volume":"285","author":"Chernov","year":"2010","journal-title":"J. Biol. Chem"},{"key":"10.1016\/j.canlet.2014.12.011_bib0135","doi-asserted-by":"crossref","first-page":"2873","DOI":"10.1021\/pr900020q","article-title":"Identification of gliotropic factors that induce human stem cell migration to malignant tumor","volume":"8","author":"An","year":"2009","journal-title":"J. Proteome Res"},{"key":"10.1016\/j.canlet.2014.12.011_bib0140","first-page":"33","article-title":"Introduction of cytogenetic tests in colorectal cancer screening","volume":"18","author":"Suceveanu","year":"2009","journal-title":"J. Gastrointestin. Liver Dis"},{"key":"10.1016\/j.canlet.2014.12.011_bib0145","doi-asserted-by":"crossref","first-page":"3432","DOI":"10.1038\/onc.2013.307","article-title":"COL11A1 promotes tumor progression and predicts poor clinical outcome in ovarian cancer","volume":"33","author":"Wu","year":"2014","journal-title":"Oncogene"},{"key":"10.1016\/j.canlet.2014.12.011_bib0150","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1038\/bjc.2013.687","article-title":"Identification of candidate circulating cisplatin-resistant biomarkers from epithelial ovarian carcinoma cell secretomes","volume":"110","author":"Teng","year":"2014","journal-title":"Br. J. Cancer"},{"key":"10.1016\/j.canlet.2014.12.011_bib0155","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1158\/1078-0432.CCR-13-1256","article-title":"A collagen-remodeling gene signature regulated by TGF-beta signaling is associated with metastasis and poor survival in serous ovarian cancer","volume":"20","author":"Cheon","year":"2014","journal-title":"Clin. Cancer Res"},{"key":"10.1016\/j.canlet.2014.12.011_bib0160","doi-asserted-by":"crossref","first-page":"5198","DOI":"10.1158\/1078-0432.CCR-08-0196","article-title":"Novel molecular subtypes of serous and endometrioid ovarian cancer linked to clinical outcome","volume":"14","author":"Tothill","year":"2008","journal-title":"Clin. Cancer Res"},{"key":"10.1016\/j.canlet.2014.12.011_bib0165","doi-asserted-by":"crossref","first-page":"852","DOI":"10.1200\/JCO.2006.08.8583","article-title":"Tumor vascular proteins as biomarkers in ovarian cancer","volume":"25","author":"Buckanovich","year":"2007","journal-title":"J. Clin. Oncol"},{"key":"10.1016\/j.canlet.2014.12.011_bib0170","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1007\/s10549-012-2123-4","article-title":"Gene expression profiling of tumour epithelial and stromal compartments during breast cancer progression","volume":"135","author":"Vargas","year":"2012","journal-title":"Breast Cancer Res. Treat"},{"key":"10.1016\/j.canlet.2014.12.011_bib0175","doi-asserted-by":"crossref","first-page":"175","DOI":"10.7150\/jca.4120","article-title":"ASPN and GJB2 are implicated in the mechanisms of invasion of ductal breast carcinomas","volume":"3","author":"Castellana","year":"2012","journal-title":"J Cancer"},{"key":"10.1016\/j.canlet.2014.12.011_bib0180","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1007\/s10549-011-1894-3","article-title":"Progression of ductal carcinoma in situ to invasive breast cancer is associated with gene expression programs of EMT and myoepithelia","volume":"133","author":"Knudsen","year":"2012","journal-title":"Breast Cancer Res. Treat"},{"key":"10.1016\/j.canlet.2014.12.011_bib0185","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1007\/s10549-006-9385-7","article-title":"Differentially expressed genes between primary cancer and paired lymph node metastases predict clinical outcome of node-positive breast cancer patients","volume":"103","author":"Feng","year":"2007","journal-title":"Breast Cancer Res. Treat"},{"key":"10.1016\/j.canlet.2014.12.011_bib0190","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1007\/s10585-008-9232-9","article-title":"A gene expression signature that defines breast cancer metastases","volume":"26","author":"Ellsworth","year":"2009","journal-title":"Clin. Exp. Metastasis"},{"key":"10.1016\/j.canlet.2014.12.011_bib0195","doi-asserted-by":"crossref","first-page":"1246","DOI":"10.1038\/modpathol.2008.129","article-title":"Collagen alpha1(XI) in normal and malignant breast tissue","volume":"21","author":"Halsted","year":"2008","journal-title":"Mod. Pathol"},{"key":"10.1016\/j.canlet.2014.12.011_bib0200","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1001\/archotol.129.7.760","article-title":"Tissue-specific gene expression of head and neck squamous cell carcinoma in vivo by complementary DNA microarray analysis","volume":"129","author":"Sok","year":"2003","journal-title":"Arch. Otolaryngol. Head Neck Surg"},{"key":"10.1016\/j.canlet.2014.12.011_bib0205","doi-asserted-by":"crossref","first-page":"3049","DOI":"10.1038\/bjc.2013.624","article-title":"Collagen type XI alpha1 facilitates head and neck squamous cell cancer growth and invasion","volume":"109","author":"Sok","year":"2013","journal-title":"Br. J. Cancer"},{"key":"10.1016\/j.canlet.2014.12.011_bib0210","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1001\/archotol.130.3.295","article-title":"Molecular profiling and the identification of genes associated with metastatic oral cavity\/pharynx squamous cell carcinoma","volume":"130","author":"Schmalbach","year":"2004","journal-title":"Arch. Otolaryngol. Head Neck Surg"},{"key":"10.1016\/j.canlet.2014.12.011_bib0215","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/j.mrgentox.2010.01.001","article-title":"Genome-wide analysis of chromosomal alterations in patients with esophageal squamous cell carcinoma exposed to tobacco and betel quid from high-risk area in India","volume":"696","author":"Chattopadhyay","year":"2010","journal-title":"Mutat. Res"},{"key":"10.1016\/j.canlet.2014.12.011_bib0220","doi-asserted-by":"crossref","first-page":"1111","DOI":"10.3892\/etm.2011.318","article-title":"Association between collagen type XI alpha1 gene polymorphisms and papillary thyroid cancer in a Korean population","volume":"2","author":"Park","year":"2011","journal-title":"Exp. Ther. Med"},{"key":"10.1016\/j.canlet.2014.12.011_bib0225","first-page":"981","article-title":"Great potential of a panel of multiple hMTH1, SPD, ITGA11 and COL11A1 markers for diagnosis of patients with non-small cell lung cancer","volume":"16","author":"Chong","year":"2006","journal-title":"Oncol. Rep"},{"key":"10.1016\/j.canlet.2014.12.011_bib0230","doi-asserted-by":"crossref","first-page":"e55414","DOI":"10.1371\/journal.pone.0055414","article-title":"Expression microarray meta-analysis identifies genes associated with Ras\/MAPK and related pathways in progression of muscle-invasive bladder transition cell carcinoma","volume":"8","author":"Ewald","year":"2013","journal-title":"PLoS ONE"},{"key":"10.1016\/j.canlet.2014.12.011_bib0235","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1002\/ar.20874","article-title":"A potential role of collagens expression in distinguishing between premalignant and malignant lesions in stomach","volume":"292","author":"Zhao","year":"2009","journal-title":"Anat. Rec. (Hoboken)"},{"key":"10.1016\/j.canlet.2014.12.011_bib0240","first-page":"11","article-title":"Anti-proCOL11A1, a new marker of infiltrating breast cancer","volume":"S5","author":"Garc\u00eda Pravia","year":"2009","journal-title":"Br. J. Surg"},{"key":"10.1016\/j.canlet.2014.12.011_bib0245","doi-asserted-by":"crossref","first-page":"5836","DOI":"10.1021\/pr300612x","article-title":"Are gastric cancer resection margin proteomic profiles more similar to those from controls or tumors?","volume":"11","author":"Aquino","year":"2012","journal-title":"J. Proteome Res"},{"key":"10.1016\/j.canlet.2014.12.011_bib0250","doi-asserted-by":"crossref","first-page":"e78327","DOI":"10.1371\/journal.pone.0078327","article-title":"Overexpression of COL11A1 by cancer-associated fibroblasts: clinical relevance of a stromal marker in pancreatic cancer","volume":"8","author":"Garcia-Pravia","year":"2013","journal-title":"PLoS ONE"},{"key":"10.1016\/j.canlet.2014.12.011_bib0255","article-title":"Overexpression of proCOL11A1 as a stromal marker of breast cancer","author":"Fuentes-Martinez","year":"2014","journal-title":"Histol. Histopathol"},{"key":"10.1016\/j.canlet.2014.12.011_bib0260","doi-asserted-by":"crossref","first-page":"1420","DOI":"10.1136\/gut.2007.148189","article-title":"Hedgehog inhibition prolongs survival in a genetically engineered mouse model of pancreatic cancer","volume":"57","author":"Feldmann","year":"2008","journal-title":"Gut"},{"key":"10.1016\/j.canlet.2014.12.011_bib0265","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1124\/mol.106.029025","article-title":"Inhibition of transforming growth factor beta signaling reduces pancreatic adenocarcinoma growth and invasiveness","volume":"72","author":"Gaspar","year":"2007","journal-title":"Mol. Pharmacol"},{"key":"10.1016\/j.canlet.2014.12.011_bib0270","doi-asserted-by":"crossref","first-page":"732","DOI":"10.1111\/j.1432-1033.1996.00732.x","article-title":"The A-domain of integrin alpha 2 binds specifically to a range of collagens but is not a general receptor for the collagenous motif","volume":"241","author":"Tuckwell","year":"1996","journal-title":"Eur. J. Biochem"},{"key":"10.1016\/j.canlet.2014.12.011_bib0275","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/S1097-2765(00)80004-0","article-title":"An orphan receptor tyrosine kinase family whose members serve as nonintegrin collagen receptors","volume":"1","author":"Shrivastava","year":"1997","journal-title":"Mol. Cell"},{"key":"10.1016\/j.canlet.2014.12.011_bib0280","doi-asserted-by":"crossref","first-page":"4660","DOI":"10.1002\/pmic.201100058","article-title":"Proteomic analysis of Col11a1-associated protein complexes","volume":"11","author":"Brown","year":"2011","journal-title":"Proteomics"}],"container-title":["Cancer Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S030438351400754X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S030438351400754X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,8,18]],"date-time":"2019-08-18T08:01:54Z","timestamp":1566115314000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S030438351400754X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,2]]},"references-count":55,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2015,2]]}},"alternative-id":["S030438351400754X"],"URL":"https:\/\/doi.org\/10.1016\/j.canlet.2014.12.011","relation":{},"ISSN":["0304-3835"],"issn-type":[{"value":"0304-3835","type":"print"}],"subject":[],"published":{"date-parts":[[2015,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Tumor matrix protein collagen XI\u03b11 in cancer","name":"articletitle","label":"Article Title"},{"value":"Cancer Letters","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.canlet.2014.12.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Elsevier Ireland Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}