{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T19:32:45Z","timestamp":1787599965123,"version":"build-2736575974"},"reference-count":25,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2016,3,1]],"date-time":"2016-03-01T00:00:00Z","timestamp":1456790400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,12,21]],"date-time":"2015-12-21T00:00:00Z","timestamp":1450656000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"name":"National Cancer Center Grant, Korea","award":["NCC-1510170-1"],"award-info":[{"award-number":["NCC-1510170-1"]}]}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","cancerletters.info","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cancer Letters"],"published-print":{"date-parts":[[2016,3]]},"DOI":"10.1016\/j.canlet.2015.12.018","type":"journal-article","created":{"date-parts":[[2015,12,23]],"date-time":"2015-12-23T09:32:00Z","timestamp":1450863120000},"page":"57-64","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"title":["Ad5\/35E1aPSESE4: A novel approach to marking circulating prostate tumor cells with a replication competent adenovirus controlled by PSA\/PSMA transcription regulatory elements"],"prefix":"10.1016","volume":"372","author":[{"given":"Ji-Eun","family":"Hwang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jae Young","family":"Joung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seung-Phil","family":"Shin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Moon-Kyung","family":"Choi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeong Eun","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yon Hui","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weon Seo","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sang-Jin","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kang Hyun","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.canlet.2015.12.018_bib0010","unstructured":"I.A.f.R.o. Cancer, W.H. Organization, GLOBOCAN: Estimated Cancer Incidence, Mortality, and Prevalence Worldwide in 2012, IARC2014."},{"issue":"8","key":"10.1016\/j.canlet.2015.12.018_bib0015","doi-asserted-by":"crossref","first-page":"e104917","DOI":"10.1371\/journal.pone.0104917","article-title":"Ethnicity is an independent determinant of age-specific PSA level: findings from a multiethnic Asian setting","volume":"9","author":"Lim","year":"2014","journal-title":"PLoS ONE"},{"key":"10.1016\/j.canlet.2015.12.018_bib0020","doi-asserted-by":"crossref","first-page":"1373","DOI":"10.1056\/NEJM200105033441806","article-title":"Prostate-specific\u2013antigen testing for early diagnosis of prostate cancer","volume":"344","author":"Barry","year":"2001","journal-title":"NEJM"},{"key":"10.1016\/j.canlet.2015.12.018_bib0025","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1016\/j.cell.2006.11.001","article-title":"Cancer metastasis: building a framework","volume":"127","author":"Gupta","year":"2006","journal-title":"Cell"},{"key":"10.1016\/j.canlet.2015.12.018_bib0030","doi-asserted-by":"crossref","first-page":"5701","DOI":"10.1158\/1078-0432.CCR-12-1587","article-title":"Meta-analysis of the prognostic value of circulating tumor cells in breast cancer","volume":"18","author":"Zhang","year":"2012","journal-title":"Clin. Cancer Res"},{"key":"10.1016\/j.canlet.2015.12.018_bib0035","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1038\/nrc3820","article-title":"Challenges in circulating tumour cell research","volume":"14","author":"Alix-Panabieres","year":"2014","journal-title":"Nat. Rev. Cancer"},{"key":"10.1016\/j.canlet.2015.12.018_bib0040","doi-asserted-by":"crossref","first-page":"2059","DOI":"10.1158\/0008-5472.CAN-12-0326","article-title":"Plastin3 is a novel marker for circulating tumor cells undergoing the epithelial\u2013mesenchymal transition and is associated with colorectal cancer prognosis","volume":"73","author":"Yokobori","year":"2013","journal-title":"Cancer Res"},{"key":"10.1016\/j.canlet.2015.12.018_bib0045","doi-asserted-by":"crossref","first-page":"7053","DOI":"10.1158\/1078-0432.CCR-07-1506","article-title":"Circulating tumor cell number and prognosis in progressive castration-resistant prostate cancer","volume":"13","author":"Danila","year":"2007","journal-title":"Clin. Cancer Res"},{"key":"10.1016\/j.canlet.2015.12.018_bib0050","doi-asserted-by":"crossref","first-page":"1026","DOI":"10.1126\/science.1194922","article-title":"Looking inside adenovirus","volume":"329","author":"Harrison","year":"2010","journal-title":"Science"},{"key":"10.1016\/j.canlet.2015.12.018_bib0055","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1016\/j.urolonc.2005.11.028","article-title":"Conditionally replicating adenovirus-mediated gene therapy in bladder cancer: an orthotopic in vivo model","volume":"24","author":"Melquist","year":"2006","journal-title":"Urol. Oncol"},{"key":"10.1016\/j.canlet.2015.12.018_bib0060","doi-asserted-by":"crossref","first-page":"4342","DOI":"10.1158\/1078-0432.CCR-03-0267","article-title":"A cox-2 promoter-based replication-selective adenoviral vector to target the cox-2-expressing human bladder cancer cells","volume":"10","author":"Shirakawa","year":"2004","journal-title":"Clin. Cancer Res"},{"key":"10.1016\/j.canlet.2015.12.018_bib0065","doi-asserted-by":"crossref","first-page":"3172","DOI":"10.1172\/JCI38609","article-title":"A simple biological imaging system for detecting viable human circulating tumor cells","volume":"119","author":"Kojima","year":"2009","journal-title":"J. Clin. Invest"},{"key":"10.1016\/j.canlet.2015.12.018_bib0070","doi-asserted-by":"crossref","first-page":"1286","DOI":"10.1002\/pros.22845","article-title":"A novel approach for detecting viable and tissue-specific circulating tumor cells through an adenovirus-based reporter vector","volume":"74","author":"Wu","year":"2014","journal-title":"Prostate"},{"key":"10.1016\/j.canlet.2015.12.018_bib0075","doi-asserted-by":"crossref","first-page":"1941","DOI":"10.1158\/0008-5472.CAN-04-3666","article-title":"Gene therapy for prostate cancer by controlling adenovirus E1a and E4 gene expression with PSES enhancer","volume":"65","author":"Li","year":"2005","journal-title":"Cancer Res"},{"key":"10.1016\/j.canlet.2015.12.018_bib0080","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1158\/1078-0432.CCR-07-0867","article-title":"Prostate-restricted replicative adenovirus expressing human endostatin-angiostatin fusion gene exhibiting dramatic antitumor efficacy","volume":"14","author":"Li","year":"2008","journal-title":"Clin. Cancer Res"},{"key":"10.1016\/j.canlet.2015.12.018_bib0085","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1016\/S0022-5347(05)63946-8","article-title":"Biochemical (prostate specific antigen) recurrence probability following radical prostatectomy for clinically localized prostate cancer","volume":"169","author":"Han","year":"2003","journal-title":"J. Urol"},{"key":"10.1016\/j.canlet.2015.12.018_bib0090","doi-asserted-by":"crossref","first-page":"1291","DOI":"10.3346\/jkms.2010.25.9.1291","article-title":"Prostate specific membrane antigen mRNA in blood as a potential predictor of biochemical recurrence after radical prostatectomy","volume":"25","author":"Joung","year":"2010","journal-title":"J. Korean Med. Sci"},{"key":"10.1016\/j.canlet.2015.12.018_bib0095","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1002\/jso.21445","article-title":"Prostate stem cell antigen mRNA in peripheral blood as a potential predictor of biochemical recurrence in high-risk prostate cancer","volume":"101","author":"Joung","year":"2010","journal-title":"J. Surg. Oncol"},{"key":"10.1016\/j.canlet.2015.12.018_bib0100","doi-asserted-by":"crossref","first-page":"6384","DOI":"10.1158\/0008-5472.CAN-13-2030","article-title":"Real-time liquid biopsy in cancer patients: fact or fiction?","volume":"73","author":"Pantel","year":"2013","journal-title":"Cancer Res"},{"key":"10.1016\/j.canlet.2015.12.018_bib0105","first-page":"1085","article-title":"Detection of circulating cytokeratin-positive cells in the blood of breast cancer patients using immunomagnetic enrichment and digital microscopy","volume":"8","author":"Witzig","year":"2002","journal-title":"Clin. Cancer Res"},{"key":"10.1016\/j.canlet.2015.12.018_bib0110","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1002\/1097-0215(20000720)89:4<337::AID-IJC4>3.0.CO;2-R","article-title":"Detection of tumor cells in blood using CD45 magnetic cell separation followed by nested mutant allele-specific amplification of p53 and K-ras genes in patients with colorectal cancer","volume":"89","author":"Iinuma","year":"2000","journal-title":"Int. J. Cancer"},{"key":"10.1016\/j.canlet.2015.12.018_bib0115","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1007\/s00432-009-0549-9","article-title":"Alpha-fetoprotein and human telomerase reverse transcriptase mRNA levels in peripheral blood of patients with hepatocellular carcinoma","volume":"135","author":"Kong","year":"2009","journal-title":"J. Cancer Res. Clin. Oncol"},{"issue":"5","key":"10.1016\/j.canlet.2015.12.018_bib0120","doi-asserted-by":"crossref","first-page":"878","DOI":"10.1007\/s10147-015-0798-3","article-title":"Detection of circulating tumor cell-specific markers in breast cancer patients using the quantitative RT-PCR assay","volume":"20","author":"Wang","year":"2015","journal-title":"Int. J. Clin. Oncol"},{"key":"10.1016\/j.canlet.2015.12.018_bib0125","first-page":"77","article-title":"Practical guide to the use of chemotherapy in castration resistant prostate cancer","volume":"21","author":"Petrylak","year":"2014","journal-title":"Can. J. Urol"},{"key":"10.1016\/j.canlet.2015.12.018_bib0130","doi-asserted-by":"crossref","first-page":"1513","DOI":"10.1056\/NEJMoa041318","article-title":"Docetaxel and estramustine compared with mitoxantrone and prednisone for advanced refractory prostate cancer","volume":"351","author":"Petrylak","year":"2004","journal-title":"NEJM"}],"container-title":["Cancer Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304383515007697?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304383515007697?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,9,13]],"date-time":"2020-09-13T04:54:17Z","timestamp":1599972857000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0304383515007697"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,3]]},"references-count":25,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2016,3]]}},"alternative-id":["S0304383515007697"],"URL":"https:\/\/doi.org\/10.1016\/j.canlet.2015.12.018","relation":{},"ISSN":["0304-3835"],"issn-type":[{"value":"0304-3835","type":"print"}],"subject":[],"published":{"date-parts":[[2016,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Ad5\/35E1aPSESE4: A novel approach to marking circulating prostate tumor cells with a replication competent adenovirus controlled by PSA\/PSMA transcription regulatory elements","name":"articletitle","label":"Article Title"},{"value":"Cancer Letters","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.canlet.2015.12.018","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 The Authors. Published by Elsevier Ireland Ltd.","name":"copyright","label":"Copyright"}]}}