{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T19:22:00Z","timestamp":1792264920505,"version":"4.4.0"},"reference-count":73,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cancer Letters"],"published-print":{"date-parts":[[2024,8]]},"DOI":"10.1016\/j.canlet.2024.217118","type":"journal-article","created":{"date-parts":[[2024,7,14]],"date-time":"2024-07-14T01:13:12Z","timestamp":1720919592000},"page":"217118","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":42,"special_numbering":"C","title":["ZDHHC9-mediated Bip\/GRP78 S-palmitoylation inhibits unfolded protein response and promotes bladder cancer progression"],"prefix":"10.1016","volume":"598","author":[{"given":"Weiquan","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1047-101X","authenticated-orcid":false,"given":"Jingchong","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tiexi","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-0376-2242","authenticated-orcid":false,"given":"Feiyi","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qi","family":"Miao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiangui","family":"Meng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen","family":"Xiao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongmei","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0218-3288","authenticated-orcid":false,"given":"Xiaoping","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.canlet.2024.217118_bib1","first-page":"209","article-title":"Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 Countries","volume":"71","author":"Sung","year":"2021","journal-title":"CA A Cancer J. Clin."},{"key":"10.1016\/j.canlet.2024.217118_bib2","first-page":"17","article-title":"Cancer statistics, 2023","volume":"73","author":"Siegel","year":"2023","journal-title":"CA A Cancer J. Clin."},{"key":"10.1016\/j.canlet.2024.217118_bib3","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1097\/CM9.0000000000001474","article-title":"Changing profiles of cancer burden worldwide and in China: a secondary analysis of the global cancer statistics 2020","volume":"134","author":"Cao","year":"2021","journal-title":"Chin. Med. J."},{"key":"10.1016\/j.canlet.2024.217118_bib4","doi-asserted-by":"crossref","first-page":"1980","DOI":"10.1001\/jama.2020.17598","article-title":"Bladder cancer: a review","volume":"324","author":"Lenis","year":"2020","journal-title":"JAMA"},{"key":"10.1016\/j.canlet.2024.217118_bib5","doi-asserted-by":"crossref","DOI":"10.1016\/j.mam.2022.101097","article-title":"Pathological implication of protein post-translational modifications in cancer","volume":"86","author":"Pan","year":"2022","journal-title":"Mol. Aspect. Med."},{"key":"10.1016\/j.canlet.2024.217118_bib6","doi-asserted-by":"crossref","DOI":"10.15252\/embr.201846666","article-title":"Protein palmitoylation and cancer","volume":"19","author":"Ko","year":"2018","journal-title":"EMBO Rep."},{"key":"10.1016\/j.canlet.2024.217118_bib7","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1038\/s41589-019-0344-0","article-title":"Toll-like receptor mediated inflammation requires FASN-dependent MYD88 palmitoylation","volume":"15","author":"Kim","year":"2019","journal-title":"Nat. Chem. Biol."},{"key":"10.1016\/j.canlet.2024.217118_bib8","doi-asserted-by":"crossref","DOI":"10.1098\/rsob.210026","article-title":"Substrate recruitment by zDHHC protein acyltransferases","volume":"11","author":"Malgapo","year":"2021","journal-title":"Open Biol."},{"key":"10.1016\/j.canlet.2024.217118_bib9","doi-asserted-by":"crossref","first-page":"5872","DOI":"10.1038\/s41467-021-26180-4","article-title":"DHHC9-mediated GLUT1 S-palmitoylation promotes glioblastoma glycolysis and tumorigenesis","volume":"12","author":"Zhang","year":"2021","journal-title":"Nat. Commun."},{"key":"10.1016\/j.canlet.2024.217118_bib10","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1038\/nature23887","article-title":"Palmitoylation-dependent activation of MC1R prevents melanomagenesis","volume":"549","author":"Chen","year":"2017","journal-title":"Nature"},{"key":"10.1016\/j.canlet.2024.217118_bib11","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1038\/s41422-018-0124-5","article-title":"Palmitoylation stabilizes PD-L1 to promote breast tumor growth","volume":"29","author":"Yang","year":"2019","journal-title":"Cell Res."},{"key":"10.1016\/j.canlet.2024.217118_bib12","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2022.111194","article-title":"S-palmitoylation of PCSK9 induces sorafenib resistance in liver cancer by activating the PI3K\/AKT pathway","volume":"40","author":"Sun","year":"2022","journal-title":"Cell Rep."},{"key":"10.1016\/j.canlet.2024.217118_bib13","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1038\/s41568-020-00312-2","article-title":"Endoplasmic reticulum stress signals in the tumour and its microenvironment","volume":"21","author":"Chen","year":"2021","journal-title":"Nat. Rev. Cancer"},{"key":"10.1016\/j.canlet.2024.217118_bib14","doi-asserted-by":"crossref","first-page":"1841","DOI":"10.1080\/15548627.2020.1788889","article-title":"The unfolded protein response regulates hepatic autophagy by sXBP1-mediated activation of TFEB","volume":"17","author":"Zhang","year":"2021","journal-title":"Autophagy"},{"key":"10.1016\/j.canlet.2024.217118_bib15","doi-asserted-by":"crossref","first-page":"1721","DOI":"10.1038\/s41388-021-01659-y","article-title":"The ER stress response mediator ERO1 triggers cancer metastasis by favoring the angiogenic switch in hypoxic conditions","volume":"40","author":"Varone","year":"2021","journal-title":"Oncogene"},{"key":"10.1016\/j.canlet.2024.217118_bib16","doi-asserted-by":"crossref","first-page":"6318","DOI":"10.1158\/0008-5472.CAN-14-0798","article-title":"SCCA1\/SERPINB3 promotes oncogenesis and epithelial-mesenchymal transition via the unfolded protein response and IL6 signaling","volume":"74","author":"Sheshadri","year":"2014","journal-title":"Cancer Res."},{"key":"10.1016\/j.canlet.2024.217118_bib17","doi-asserted-by":"crossref","first-page":"2018","DOI":"10.1016\/j.cmet.2022.10.010","article-title":"Cancer cell-intrinsic XBP1 drives immunosuppressive reprogramming of intratumoral myeloid cells by promoting cholesterol production","volume":"34","author":"Yang","year":"2022","journal-title":"Cell Metabol."},{"key":"10.1016\/j.canlet.2024.217118_bib18","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1002\/jcp.21340","article-title":"GRP78 and Raf-1 cooperatively confer resistance to endoplasmic reticulum stress-induced apoptosis","volume":"215","author":"Shu","year":"2008","journal-title":"J. Cell. Physiol."},{"key":"10.1016\/j.canlet.2024.217118_bib19","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1038\/s41590-022-01145-x","article-title":"PERK is a critical metabolic hub for immunosuppressive function in macrophages","volume":"23","author":"Raines","year":"2022","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.canlet.2024.217118_bib20","series-title":"Tandem Molecular Self-Assembly Selectively Inhibits Lung Cancer Cells by Inducing Endoplasmic Reticulum Stress","author":"Zheng","year":"2019"},{"key":"10.1016\/j.canlet.2024.217118_bib21","doi-asserted-by":"crossref","first-page":"2833","DOI":"10.7150\/ijbs.70544","article-title":"ZDHHC22-mediated mTOR palmitoylation restrains breast cancer growth and endocrine therapy resistance","volume":"18","author":"Huang","year":"2022","journal-title":"Int. J. Biol. Sci."},{"key":"10.1016\/j.canlet.2024.217118_bib22","doi-asserted-by":"crossref","first-page":"978","DOI":"10.1038\/s41556-019-0361-y","article-title":"5-methylcytosine promotes pathogenesis of bladder cancer through stabilizing mRNAs","volume":"21","author":"Chen","year":"2019","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.canlet.2024.217118_bib23","doi-asserted-by":"crossref","first-page":"2660","DOI":"10.1200\/JCO.2009.25.0977","article-title":"Expression signature of E2F1 and its associated genes predict superficial to invasive progression of bladder tumors","volume":"28","author":"Lee","year":"2010","journal-title":"J. Clin. Oncol."},{"key":"10.1016\/j.canlet.2024.217118_bib24","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.canlet.2019.01.046","article-title":"ZBTB7A, a miR-663a target gene, protects osteosarcoma from endoplasmic reticulum stress-induced apoptosis by suppressing LncRNA GAS5 expression","volume":"448","author":"Zhang","year":"2019","journal-title":"Cancer Lett."},{"key":"10.1016\/j.canlet.2024.217118_bib25","doi-asserted-by":"crossref","first-page":"17","DOI":"10.4161\/adip.22117","article-title":"Proteomic analysis of protein palmitoylation in adipocytes","volume":"2","author":"Ren","year":"2013","journal-title":"Adipocyte"},{"key":"10.1016\/j.canlet.2024.217118_bib26","doi-asserted-by":"crossref","first-page":"2299","DOI":"10.1007\/s43032-022-00919-w","article-title":"Proteome-wide identification of palmitoylated proteins in mouse testis","volume":"29","author":"Gao","year":"2022","journal-title":"Reprod. Sci."},{"key":"10.1016\/j.canlet.2024.217118_bib27","doi-asserted-by":"crossref","first-page":"3299","DOI":"10.1038\/s41598-017-03562-7","article-title":"Analysis of the brain palmitoyl-proteome using both acyl-biotin exchange and acyl-resin-assisted capture methods","volume":"7","author":"Edmonds","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.canlet.2024.217118_bib28","doi-asserted-by":"crossref","first-page":"7082","DOI":"10.1021\/ja311416v","article-title":"2-Bromopalmitate analogues as activity-based probes to explore palmitoyl acyltransferases","volume":"135","author":"Zheng","year":"2013","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.canlet.2024.217118_bib29","doi-asserted-by":"crossref","first-page":"261","DOI":"10.12688\/f1000research.6464.1","article-title":"SwissPalm: protein palmitoylation database","volume":"4","author":"Blanc","year":"2015","journal-title":"F1000Res"},{"key":"10.1016\/j.canlet.2024.217118_bib30","first-page":"203","article-title":"SwissPalm 2: protein S-palmitoylation database","author":"Blanc","year":"2009","journal-title":"Methods Mol. Biol."},{"key":"10.1016\/j.canlet.2024.217118_bib31","doi-asserted-by":"crossref","first-page":"1836","DOI":"10.1093\/bib\/bbaa038","article-title":"GPS-Palm: a deep learning-based graphic presentation system for the prediction of S-palmitoylation sites in proteins","volume":"22","author":"Ning","year":"2021","journal-title":"Briefings Bioinf."},{"key":"10.1016\/j.canlet.2024.217118_bib32","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1038\/s41392-024-01759-7","article-title":"Protein lipidation in health and disease: molecular basis, physiological function and pathological implication","volume":"9","author":"Yuan","year":"2024","journal-title":"Signal Transduct. Targeted Ther."},{"key":"10.1016\/j.canlet.2024.217118_bib33","doi-asserted-by":"crossref","first-page":"6370","DOI":"10.1038\/s41467-023-42170-0","article-title":"Palmitoylation-driven PHF2 ubiquitination remodels lipid metabolism through the SREBP1c axis in hepatocellular carcinoma","volume":"14","author":"Jeong","year":"2023","journal-title":"Nat. Commun."},{"key":"10.1016\/j.canlet.2024.217118_bib34","doi-asserted-by":"crossref","first-page":"6682","DOI":"10.1038\/s41467-023-42476-z","article-title":"Palmitoyltransferase DHHC9 and acyl protein thioesterase APT1 modulate renal fibrosis through regulating \u03b2-catenin palmitoylation","volume":"14","author":"Gu","year":"2023","journal-title":"Nat. Commun."},{"key":"10.1016\/j.canlet.2024.217118_bib35","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.pharmthera.2015.05.008","article-title":"Sp1 transcription factor: a long-standing target in cancer chemotherapy","volume":"152","author":"Vizca\u00edno","year":"2015","journal-title":"Pharmacol. Ther."},{"key":"10.1016\/j.canlet.2024.217118_bib36","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1111\/febs.13148","article-title":"Sp1 and the 'hallmarks of cancer'","volume":"282","author":"Beishline","year":"2015","journal-title":"FEBS J."},{"key":"10.1016\/j.canlet.2024.217118_bib37","doi-asserted-by":"crossref","first-page":"2034","DOI":"10.1158\/0008-5472.CAN-22-3105","article-title":"ZDHHC2-Mediated AGK palmitoylation activates AKT-mTOR signaling to reduce sunitinib sensitivity in renal cell carcinoma","volume":"83","author":"Sun","year":"2023","journal-title":"Cancer Res."},{"key":"10.1016\/j.canlet.2024.217118_bib38","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1038\/s41420-022-01242-8","article-title":"Stepwise molecular mechanisms responsible for chemoresistance in bladder cancer cells","volume":"8","author":"Mun","year":"2022","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.canlet.2024.217118_bib39","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1038\/s41467-023-36462-8","article-title":"Integrative proteomic characterization of adenocarcinoma of esophagogastric junction","volume":"14","author":"Li","year":"2023","journal-title":"Nat. Commun."},{"key":"10.1016\/j.canlet.2024.217118_bib40","doi-asserted-by":"crossref","first-page":"D1083","DOI":"10.1093\/nar\/gkaa968","article-title":"CellMiner Cross-Database (CellMinerCDB) version 1.2: exploration of patient-derived cancer cell line pharmacogenomics","volume":"49","author":"Luna","year":"2021","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.canlet.2024.217118_bib41","doi-asserted-by":"crossref","first-page":"1044","DOI":"10.1016\/j.ccell.2022.08.010","article-title":"Acquired semi-squamatization during chemotherapy suggests differentiation as a therapeutic strategy for bladder cancer","volume":"40","author":"Wang","year":"2022","journal-title":"Cancer Cell"},{"key":"10.1016\/j.canlet.2024.217118_bib42","first-page":"322","volume":"vol. 7","author":"Shi","year":"2024"},{"key":"10.1016\/j.canlet.2024.217118_bib43","doi-asserted-by":"crossref","first-page":"1225","DOI":"10.1038\/leu.2015.293","article-title":"Palmitoylacyltransferase Zdhhc9 inactivation mitigates leukemogenic potential of oncogenic Nras","volume":"30","author":"Liu","year":"2016","journal-title":"Leukemia"},{"key":"10.1016\/j.canlet.2024.217118_bib44","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1007\/s11626-023-00755-5","article-title":"Involvement of ZDHHC9 in lung adenocarcinoma: regulation of PD-L1 stability via palmitoylation","volume":"59","author":"Li","year":"2023","journal-title":"In Vitro Cell. Dev. Biol. Anim."},{"key":"10.1016\/j.canlet.2024.217118_bib45","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2023.114567","article-title":"Targeting ZDHHC9 potentiates anti-programmed death-ligand 1 immunotherapy of pancreatic cancer by modifying the tumor microenvironment","volume":"161","author":"Lin","year":"2023","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.canlet.2024.217118_bib46","doi-asserted-by":"crossref","first-page":"5","DOI":"10.3892\/ol.2022.13591","article-title":"ZDHHC9 promotes colon tumor growth by inhibiting effector T cells","volume":"25","author":"Chong","year":"2023","journal-title":"Oncol. Lett."},{"key":"10.1016\/j.canlet.2024.217118_bib47","doi-asserted-by":"crossref","first-page":"3520","DOI":"10.1016\/j.molcel.2023.09.007","article-title":"Targeting LYPLAL1-mediated cGAS depalmitoylation enhances the response to anti-tumor immunotherapy","volume":"83","author":"Fan","year":"2023","journal-title":"Mol. Cell."},{"key":"10.1016\/j.canlet.2024.217118_bib48","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2022.102380","article-title":"Protein palmitoylation-mediated palmitic acid sensing causes blood-testis barrier damage via inducing ER stress","volume":"54","author":"Ge","year":"2022","journal-title":"Redox Biol."},{"key":"10.1016\/j.canlet.2024.217118_bib49","doi-asserted-by":"crossref","first-page":"E1390","DOI":"10.1152\/ajpendo.00519.2011","article-title":"A role for aberrant protein palmitoylation in FFA-induced ER stress and \u03b2-cell death","volume":"302","author":"Baldwin","year":"2012","journal-title":"Am. J. Physiol. Endocrinol. Metab."},{"key":"10.1016\/j.canlet.2024.217118_bib50","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1126\/science.1209038","article-title":"The unfolded protein response: from stress pathway to homeostatic regulation","volume":"334","author":"Walter","year":"2011","journal-title":"Science"},{"key":"10.1016\/j.canlet.2024.217118_bib51","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/S0169-328X(99)00188-6","article-title":"KDEL proteins are found on the surface of NG108-15 cells","volume":"72","author":"Xiao","year":"1999","journal-title":"Mol. Brain Res."},{"key":"10.1016\/j.canlet.2024.217118_bib52","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1016\/S0198-8859(01)00269-5","article-title":"Major histocompatibility class one molecule associates with glucose regulated protein (GRP) 78 on the cell surface","volume":"62","author":"Triantafilou","year":"2001","journal-title":"Hum. Immunol."},{"key":"10.1016\/j.canlet.2024.217118_bib53","doi-asserted-by":"crossref","first-page":"15065","DOI":"10.1074\/jbc.M109.087445","article-title":"Cell surface relocalization of the endoplasmic reticulum chaperone and unfolded protein response regulator GRP78\/BiP","volume":"285","author":"Zhang","year":"2010","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.canlet.2024.217118_bib54","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/j.ccr.2004.08.018","article-title":"Cell surface expression of the stress response chaperone GRP78 enables tumor targeting by circulating ligands","volume":"6","author":"Arap","year":"2004","journal-title":"Cancer Cell"},{"key":"10.1016\/j.canlet.2024.217118_bib55","doi-asserted-by":"crossref","first-page":"4663","DOI":"10.1158\/0008-5472.CAN-04-3426","article-title":"Kringle 5 of human plasminogen induces apoptosis of endothelial and tumor cells through surface-expressed glucose-regulated protein 78","volume":"65","author":"Davidson","year":"2005","journal-title":"Cancer Res."},{"key":"10.1016\/j.canlet.2024.217118_bib56","doi-asserted-by":"crossref","first-page":"45","DOI":"10.2174\/156652406775574523","article-title":"Stress induction of GRP78\/BiP and its role in cancer","volume":"6","author":"Li","year":"2006","journal-title":"Curr. Mol. Med."},{"key":"10.1016\/j.canlet.2024.217118_bib57","doi-asserted-by":"crossref","first-page":"1417","DOI":"10.1002\/jcp.24578","article-title":"GRP78 mediates cell growth and invasiveness in endometrial cancer","volume":"229","author":"Cal\u00ec","year":"2014","journal-title":"J. Cell. Physiol."},{"key":"10.1016\/j.canlet.2024.217118_bib58","doi-asserted-by":"crossref","first-page":"2914","DOI":"10.1038\/s41467-019-10824-7","article-title":"The deubiquitylase OTUD3 stabilizes GRP78 and promotes lung tumorigenesis","volume":"10","author":"Du","year":"2019","journal-title":"Nat. Commun."},{"key":"10.1016\/j.canlet.2024.217118_bib59","doi-asserted-by":"crossref","first-page":"3177","DOI":"10.1038\/s41418-020-0571-7","article-title":"Ubiquitin ligase CHIP regulates OTUD3 stability and suppresses tumour metastasis in lung cancer","volume":"27","author":"Zhang","year":"2020","journal-title":"Cell Death Differ."},{"key":"10.1016\/j.canlet.2024.217118_bib60","doi-asserted-by":"crossref","first-page":"2064","DOI":"10.1158\/0008-5472.CAN-16-1979","article-title":"HSPA5 regulates ferroptotic cell death in cancer cells","volume":"77","author":"Zhu","year":"2017","journal-title":"Cancer Res."},{"key":"10.1016\/j.canlet.2024.217118_bib61","doi-asserted-by":"crossref","DOI":"10.26508\/lsa.201900377","article-title":"GRP78 regulates CD44v membrane homeostasis and cell spreading in tamoxifen-resistant breast cancer","volume":"2","author":"Tseng","year":"2019","journal-title":"Life Sci. Alliance"},{"key":"10.1016\/j.canlet.2024.217118_bib62","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1038\/s41392-021-00580-w","article-title":"The deubiquitinase USP11 promotes ovarian cancer chemoresistance by stabilizing BIP","volume":"6","author":"Zhu","year":"2021","journal-title":"Signal Transduct. Targeted Ther."},{"key":"10.1016\/j.canlet.2024.217118_bib63","doi-asserted-by":"crossref","first-page":"3960","DOI":"10.1182\/blood-2009-03-209668","article-title":"GRP-78 secreted by tumor cells blocks the antiangiogenic activity of bortezomib","volume":"114","author":"Kern","year":"2009","journal-title":"Blood"},{"key":"10.1016\/j.canlet.2024.217118_bib64","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1002\/iub.2502","article-title":"Glucose-regulated protein (GRP78) is an important cell surface receptor for viral invasion, cancers, and neurological disorders","volume":"73","author":"Gonzalez-Gronow","year":"2021","journal-title":"IUBMB Life"},{"key":"10.1016\/j.canlet.2024.217118_bib65","doi-asserted-by":"crossref","DOI":"10.1038\/srep34922","article-title":"Cell surface GRP78 as a biomarker and target for suppressing glioma cells","volume":"6","author":"Kang","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.canlet.2024.217118_bib66","doi-asserted-by":"crossref","first-page":"1367","DOI":"10.1002\/ijc.32012","article-title":"CLPTM1L\/CRR9 ectodomain interaction with GRP78 at the cell surface signals for survival and chemoresistance upon ER stress in pancreatic adenocarcinoma cells","volume":"144","author":"Clarke","year":"2019","journal-title":"Int. J. Cancer"},{"key":"10.1016\/j.canlet.2024.217118_bib67","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1042\/BJ20100286","article-title":"Temporal regulation of Cat-1 (cationic amino acid transporter-1) gene transcription during endoplasmic reticulum stress","volume":"429","author":"Huang","year":"2010","journal-title":"Biochem. J."},{"key":"10.1016\/j.canlet.2024.217118_bib68","doi-asserted-by":"crossref","first-page":"1564","DOI":"10.1038\/s41598-017-01696-2","article-title":"Inhibition of Sp1 prevents ER homeostasis and causes cell death by lysosomal membrane permeabilization in pancreatic cancer","volume":"7","author":"Dauer","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.canlet.2024.217118_bib69","doi-asserted-by":"crossref","first-page":"1557","DOI":"10.1002\/jcp.24599","article-title":"Glucosamine-induced Sp1 O-GlcNAcylation ameliorates hypoxia-induced SGLT dysfunction in primary cultured renal proximal tubule cells","volume":"229","author":"Suh","year":"2014","journal-title":"J. Cell. Physiol."},{"key":"10.1016\/j.canlet.2024.217118_bib70","article-title":"SLC17A9-PTHLH-EMT axis promotes proliferation and invasion of clear renal cell carcinoma","volume":"26","author":"Li","year":"2023","journal-title":"iScience"},{"key":"10.1016\/j.canlet.2024.217118_bib71","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/j.biopsych.2018.09.024","article-title":"Gephyrin palmitoylation in basolateral amygdala mediates the anxiolytic action of benzodiazepine","volume":"85","author":"Shen","year":"2019","journal-title":"Biol. Psychiatr."},{"key":"10.1016\/j.canlet.2024.217118_bib72","article-title":"DHHC2 regulates fear memory formation, LTP, and AKAP150 signaling in the hippocampus","volume":"26","author":"Li","year":"2023","journal-title":"iScience"},{"key":"10.1016\/j.canlet.2024.217118_bib73","doi-asserted-by":"crossref","first-page":"D956","DOI":"10.1093\/nar\/gkx1090","article-title":"LinkedOmics: analyzing multi-omics data within and across 32 cancer types","volume":"46","author":"Vasaikar","year":"2018","journal-title":"Nucleic Acids Res."}],"container-title":["Cancer Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304383524005135?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304383524005135?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T19:42:51Z","timestamp":1760816571000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0304383524005135"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8]]},"references-count":73,"alternative-id":["S0304383524005135"],"URL":"https:\/\/doi.org\/10.1016\/j.canlet.2024.217118","relation":{},"ISSN":["0304-3835"],"issn-type":[{"value":"0304-3835","type":"print"}],"subject":[],"published":{"date-parts":[[2024,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"ZDHHC9-mediated Bip\/GRP78 S-palmitoylation inhibits unfolded protein response and promotes bladder cancer progression","name":"articletitle","label":"Article Title"},{"value":"Cancer Letters","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.canlet.2024.217118","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"217118"}}