{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T09:06:10Z","timestamp":1790413570682,"version":"4.1.0"},"reference-count":99,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100010256","name":"Guangzhou Municipal Science and Technology Project","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010256","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cancer Letters"],"published-print":{"date-parts":[[2024,11]]},"DOI":"10.1016\/j.canlet.2024.217286","type":"journal-article","created":{"date-parts":[[2024,10,15]],"date-time":"2024-10-15T15:18:04Z","timestamp":1729005484000},"page":"217286","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"special_numbering":"C","title":["Evaluation of glucocorticoid-related genes reveals GPD1 as a therapeutic target and regulator of sphingosine 1-phosphate metabolism in CRPC"],"prefix":"10.1016","volume":"605","author":[{"given":"Ren","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhihao","family":"Zou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhengrong","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huichan","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming","family":"Xi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yingke","family":"Liang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianheng","family":"Ye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qishan","family":"Dai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongding","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huijing","family":"Tan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weide","family":"Zhong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4925-7232","authenticated-orcid":false,"given":"Zongren","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1647-1259","authenticated-orcid":false,"given":"Yuxiang","family":"Liang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.canlet.2024.217286_bib1","first-page":"8","article-title":"Nature reviews","volume":"7","year":"2021","journal-title":"Disease primers"},{"issue":"12","key":"10.1016\/j.canlet.2024.217286_bib2","doi-asserted-by":"crossref","first-page":"a030361","DOI":"10.1101\/cshperspect.a030361","article-title":"The epidemiology of prostate cancer","volume":"8","author":"Pernar","year":"2018","journal-title":"Cold Spring Harbor Perspect. Med."},{"key":"10.1016\/j.canlet.2024.217286_bib3","doi-asserted-by":"crossref","DOI":"10.1016\/j.pharmthera.2021.107932","article-title":"Prostate Cancer Biomarkers: from diagnosis to prognosis and precision-guided therapeutics","volume":"228","author":"Adamaki","year":"2021","journal-title":"Pharmacol. Therapeut."},{"issue":"15","key":"10.1016\/j.canlet.2024.217286_bib4","doi-asserted-by":"crossref","first-page":"1405","DOI":"10.1056\/NEJMcp2209151","article-title":"Screening for prostate cancer","volume":"388","author":"Pinsky","year":"2023","journal-title":"N. Engl. J. Med."},{"issue":"3","key":"10.1016\/j.canlet.2024.217286_bib5","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1210\/endrev\/bnab002","article-title":"Hormonal therapy for prostate cancer","volume":"42","author":"Desai","year":"2021","journal-title":"Endocr. Rev."},{"key":"10.1016\/j.canlet.2024.217286_bib6","doi-asserted-by":"crossref","DOI":"10.1016\/j.canlet.2023.216468","article-title":"Androgen receptor inhibition suppresses anti-tumor neutrophil response against bone metastatic prostate cancer via regulation of T\u03b2RI expression","volume":"579","author":"Alsamraae","year":"2023","journal-title":"Cancer Lett."},{"issue":"28","key":"10.1016\/j.canlet.2024.217286_bib7","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2322203121","article-title":"Single-cell analysis of treatment-resistant prostate cancer: implications of cell state changes for cell surface antigen-targeted therapies","volume":"121","author":"Zaidi","year":"2024","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.canlet.2024.217286_bib8","doi-asserted-by":"crossref","DOI":"10.1016\/j.canlet.2022.215992","article-title":"Exploring prostate cancer in the post-genomic era","volume":"553","author":"Chua","year":"2023","journal-title":"Cancer Lett."},{"issue":"1","key":"10.1016\/j.canlet.2024.217286_bib9","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1186\/s12894-024-01483-y","article-title":"The effect of a fermented soy beverage among patients with localized prostate cancer prior to radical prostatectomy","volume":"24","author":"Lokeshwar","year":"2024","journal-title":"BMC Urol."},{"key":"10.1016\/j.canlet.2024.217286_bib10","doi-asserted-by":"crossref","DOI":"10.1016\/j.canlet.2023.216247","article-title":"Non-coding RNAs in enzalutamide resistance of castration-resistant prostate cancer","volume":"566","author":"Gao","year":"2023","journal-title":"Cancer Lett."},{"issue":"11","key":"10.1016\/j.canlet.2024.217286_bib11","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1038\/s41585-019-0237-8","article-title":"Towards precision oncology in advanced prostate cancer","volume":"16","author":"Ku","year":"2019","journal-title":"Nat. Rev. Urol."},{"issue":"5","key":"10.1016\/j.canlet.2024.217286_bib12","first-page":"1207","article-title":"Nuclear receptors: recent drug discovery for cancer therapies","volume":"40","author":"Zhao","year":"2019","journal-title":"Endocr. Rev."},{"key":"10.1016\/j.canlet.2024.217286_bib13","doi-asserted-by":"crossref","DOI":"10.1016\/j.canlet.2023.216188","article-title":"Monoamine oxidase A (MAOA): a promising target for prostate cancer therapy","volume":"563","author":"Han","year":"2023","journal-title":"Cancer Lett."},{"issue":"5","key":"10.1016\/j.canlet.2024.217286_bib14","doi-asserted-by":"crossref","first-page":"1701","DOI":"10.1002\/med.21961","article-title":"Current and emerging approaches to noncompetitive AR inhibition","volume":"43","author":"Riley","year":"2023","journal-title":"Med. Res. Rev."},{"issue":"8","key":"10.1016\/j.canlet.2024.217286_bib15","doi-asserted-by":"crossref","first-page":"1775","DOI":"10.1002\/ijc.31818","article-title":"Interference with the androgen receptor protein stability in therapy-resistant prostate cancer","volume":"144","author":"Lakshmana","year":"2019","journal-title":"Int. J. Cancer"},{"issue":"12","key":"10.1016\/j.canlet.2024.217286_bib16","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1038\/nrc4016","article-title":"Emerging mechanisms of resistance to androgen receptor inhibitors in prostate cancer","volume":"15","author":"Watson","year":"2015","journal-title":"Nat. Rev. Cancer"},{"issue":"6","key":"10.1016\/j.canlet.2024.217286_bib17","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1016\/j.cell.2013.11.012","article-title":"Glucocorticoid receptor confers resistance to antiandrogens by bypassing androgen receptor blockade","volume":"155","author":"Arora","year":"2013","journal-title":"Cell"},{"issue":"1","key":"10.1016\/j.canlet.2024.217286_bib18","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1038\/nrurol.2015.254","article-title":"Androgen-glucocorticoid interactions in the era of novel prostate cancer therapy","volume":"13","author":"Narayanan","year":"2016","journal-title":"Nat. Rev. Urol."},{"issue":"12","key":"10.1016\/j.canlet.2024.217286_bib19","doi-asserted-by":"crossref","first-page":"2217","DOI":"10.1007\/s00018-017-2467-3","article-title":"Comparing the rules of engagement of androgen and glucocorticoid receptors","volume":"74","author":"Claessens","year":"2017","journal-title":"Cell. Mol. Life Sci. : CMLS"},{"issue":"19","key":"10.1016\/j.canlet.2024.217286_bib20","doi-asserted-by":"crossref","DOI":"10.1002\/adhm.202304618","article-title":"Prostate-specific membrane antigen targeted StarPEG nanocarrier for imaging and therapy of prostate cancer","volume":"13","author":"Meher","year":"2024","journal-title":"Adv. Healthcare Mater."},{"issue":"5","key":"10.1016\/j.canlet.2024.217286_bib21","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1016\/S1470-2045(06)70694-5","article-title":"Glucocorticoid use in prostate cancer and other solid tumours: implications for effectiveness of cytotoxic treatment and metastases","volume":"7","author":"Herr","year":"2006","journal-title":"Lancet Oncol."},{"issue":"10336","key":"10.1016\/j.canlet.2024.217286_bib22","doi-asserted-by":"crossref","first-page":"1695","DOI":"10.1016\/S0140-6736(22)00367-1","article-title":"Abiraterone plus prednisone added to androgen deprivation therapy and docetaxel in de novo metastatic castration-sensitive prostate cancer (PEACE-1): a multicentre, open-label, randomised, phase 3 study with a 2 \u00d7 2 factorial design","volume":"399","author":"Fizazi","year":"2022","journal-title":"Lancet (London, England)"},{"key":"10.1016\/j.canlet.2024.217286_bib23","doi-asserted-by":"crossref","DOI":"10.1016\/j.canlet.2023.216209","article-title":"SOX2 expression in prostate cancer drives resistance to nuclear hormone receptor signaling inhibition through the WEE1\/CDK1 signaling axis","volume":"565","author":"Williams","year":"2023","journal-title":"Cancer Lett."},{"issue":"2","key":"10.1016\/j.canlet.2024.217286_bib24","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1007\/s12672-014-0173-2","article-title":"Glucocorticoid receptor activity contributes to resistance to androgen-targeted therapy in prostate cancer","volume":"5","author":"Isikbay","year":"2014","journal-title":"Hormones Cancer"},{"issue":"5","key":"10.1016\/j.canlet.2024.217286_bib25","doi-asserted-by":"crossref","first-page":"1570","DOI":"10.1158\/0008-5472.CAN-12-2350","article-title":"FoxA1 specifies unique androgen and glucocorticoid receptor binding events in prostate cancer cells","volume":"73","author":"Sahu","year":"2013","journal-title":"Cancer Res."},{"issue":"15","key":"10.1016\/j.canlet.2024.217286_bib26","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2322563121","article-title":"Development of an orally bioavailable mSWI\/SNF ATPase degrader and acquired mechanisms of resistance in prostate cancer","volume":"121","author":"He","year":"2024","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"issue":"2","key":"10.1016\/j.canlet.2024.217286_bib27","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1111\/bph.15300","article-title":"Mechanisms of enzalutamide resistance in castration-resistant prostate cancer and therapeutic strategies to overcome it","volume":"178","author":"Wang","year":"2021","journal-title":"Br. J. Pharmacol."},{"issue":"3","key":"10.1016\/j.canlet.2024.217286_bib28","doi-asserted-by":"crossref","first-page":"354","DOI":"10.4103\/1008-682X.125392","article-title":"Glucocorticoids and prostate cancer treatment: friend or foe?","volume":"16","author":"Montgomery","year":"2014","journal-title":"Asian J. Androl."},{"issue":"21","key":"10.1016\/j.canlet.2024.217286_bib29","doi-asserted-by":"crossref","first-page":"5417","DOI":"10.3390\/cancers13215417","article-title":"Androgen receptor signaling in prostate cancer and therapeutic strategies","volume":"13","author":"Jacob","year":"2021","journal-title":"Cancers"},{"issue":"1","key":"10.1016\/j.canlet.2024.217286_bib30","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.ajhg.2011.11.028","article-title":"Transient infantile hypertriglyceridemia, fatty liver, and hepatic fibrosis caused by mutated GPD1, encoding glycerol-3-phosphate dehydrogenase 1","volume":"90","author":"Basel-Vanagaite","year":"2012","journal-title":"Am. J. Hum. Genet."},{"issue":"9","key":"10.1016\/j.canlet.2024.217286_bib31","doi-asserted-by":"crossref","first-page":"3280","DOI":"10.1073\/pnas.0712331105","article-title":"Structure of glycerol-3-phosphate dehydrogenase, an essential monotopic membrane enzyme involved in respiration and metabolism","volume":"105","author":"Yeh","year":"2008","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"issue":"8","key":"10.1016\/j.canlet.2024.217286_bib32","doi-asserted-by":"crossref","first-page":"1764","DOI":"10.3390\/cells9081764","article-title":"Role of mitochondrial glycerol-3-phosphate dehydrogenase in metabolic adaptations of prostate cancer","volume":"9","author":"Pecinov\u00e1","year":"2020","journal-title":"Cells"},{"issue":"1","key":"10.1016\/j.canlet.2024.217286_bib33","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1186\/s13045-022-01312-5","article-title":"Allosteric activation of the metabolic enzyme GPD1 inhibits bladder cancer growth via the lysoPC-PAFR-TRPV2 axis","volume":"15","author":"Zhang","year":"2022","journal-title":"J. Hematol. Oncol."},{"issue":"2","key":"10.1016\/j.canlet.2024.217286_bib34","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/j.stem.2019.06.004","article-title":"GPD1 specifically marks dormant glioma stem cells with a distinct metabolic profile","volume":"25","author":"Rusu","year":"2019","journal-title":"Cell Stem Cell"},{"issue":"7","key":"10.1016\/j.canlet.2024.217286_bib35","doi-asserted-by":"crossref","first-page":"e337","DOI":"10.1016\/S2666-7568(23)00085-5","article-title":"Effects of putative metformin targets on phenotypic age and leukocyte telomere length: a mendelian randomisation study using data from the UK Biobank","volume":"4","author":"Luo","year":"2023","journal-title":"Lancet. Health. Longevity"},{"issue":"11","key":"10.1016\/j.canlet.2024.217286_bib36","doi-asserted-by":"crossref","first-page":"2150","DOI":"10.1158\/0008-5472.CAN-19-2852","article-title":"GPD1 enhances the anticancer effects of metformin by synergistically increasing total cellular glycerol-3-phosphate","volume":"80","author":"Xie","year":"2020","journal-title":"Cancer Res."},{"issue":"1","key":"10.1016\/j.canlet.2024.217286_bib37","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1186\/s13046-021-01996-6","article-title":"A HIF1\u03b1-GPD1 feedforward loop inhibits the progression of renal clear cell carcinoma via mitochondrial function and lipid metabolism","volume":"40","author":"Liu","year":"2021","journal-title":"J. Exp. Clin. Cancer Res. : CR"},{"issue":"1","key":"10.1016\/j.canlet.2024.217286_bib38","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1038\/s42003-020-01476-1","article-title":"Single-cell analysis supports a luminal-neuroendocrine transdifferentiation in human prostate cancer","volume":"3","author":"Dong","year":"2020","journal-title":"Commun. Biol."},{"issue":"2","key":"10.1016\/j.canlet.2024.217286_bib39","doi-asserted-by":"crossref","DOI":"10.1093\/bib\/bbac029","article-title":"Multi-variable AUC for sifting complementary features and its biomedical application","volume":"23","author":"Su","year":"2022","journal-title":"Briefings Bioinf."},{"key":"10.1016\/j.canlet.2024.217286_bib40","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.1016\/j.csbj.2021.01.028","article-title":"Machine learning applications in microbial ecology, human microbiome studies, and environmental monitoring","volume":"19","author":"Ghannam","year":"2021","journal-title":"Comput. Struct. Biotechnol. J."},{"key":"10.1016\/j.canlet.2024.217286_bib41","doi-asserted-by":"crossref","first-page":"4003","DOI":"10.1016\/j.csbj.2021.07.003","article-title":"Machine learning in the prediction of cancer therapy","volume":"19","author":"Rafique","year":"2021","journal-title":"Comput. Struct. Biotechnol. J."},{"issue":"5","key":"10.1016\/j.canlet.2024.217286_bib42","doi-asserted-by":"crossref","first-page":"540","DOI":"10.4103\/aja2021104","article-title":"Mannose inhibits the growth of prostate cancer through a mitochondrial mechanism","volume":"24","author":"Deng","year":"2022","journal-title":"Asian J. Androl."},{"issue":"1","key":"10.1016\/j.canlet.2024.217286_bib43","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1038\/s41419-024-06450-x","article-title":"FKBP10 promotes clear cell renal cell carcinoma progression and regulates sensitivity to the HIF2\u03b1 blockade by facilitating LDHA phosphorylation","volume":"15","author":"Liu","year":"2024","journal-title":"Cell Death Dis."},{"issue":"14","key":"10.1016\/j.canlet.2024.217286_bib44","doi-asserted-by":"crossref","first-page":"1547","DOI":"10.1002\/pros.22704","article-title":"Metabolomic signatures of aggressive prostate cancer","volume":"73","author":"McDunn","year":"2013","journal-title":"Prostate"},{"issue":"11","key":"10.1016\/j.canlet.2024.217286_bib45","doi-asserted-by":"crossref","first-page":"5117","DOI":"10.1158\/0008-5472.CAN-06-4040","article-title":"Molecular features of hormone-refractory prostate cancer cells by genome-wide gene expression profiles","volume":"67","author":"Tamura","year":"2007","journal-title":"Cancer Res."},{"issue":"1","key":"10.1016\/j.canlet.2024.217286_bib46","doi-asserted-by":"crossref","first-page":"4279","DOI":"10.1038\/s41467-020-17645-z","article-title":"Caveolin-1-mediated sphingolipid oncometabolism underlies a metabolic vulnerability of prostate cancer","volume":"11","author":"Vykoukal","year":"2020","journal-title":"Nat. Commun."},{"key":"10.1016\/j.canlet.2024.217286_bib47","doi-asserted-by":"crossref","DOI":"10.1016\/j.fsigen.2021.102599","article-title":"Evaluating the effects of whole genome amplification strategies for amplifying trace DNA using capillary electrophoresis and massive parallel sequencing","volume":"56","author":"Xu","year":"2022","journal-title":"Forensic Sci. Int. Genetics"},{"issue":"6463","key":"10.1016\/j.canlet.2024.217286_bib48","doi-asserted-by":"crossref","DOI":"10.1126\/science.aar5551","article-title":"Sphingosine 1-phosphate: lipid signaling in pathology and therapy","volume":"366","author":"Cartier","year":"2019","journal-title":"Science (New York, N.Y.)"},{"issue":"7301","key":"10.1016\/j.canlet.2024.217286_bib49","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1038\/nature09128","article-title":"Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2","volume":"465","author":"Alvarez","year":"2010","journal-title":"Nature"},{"issue":"10","key":"10.1016\/j.canlet.2024.217286_bib50","doi-asserted-by":"crossref","first-page":"2732","DOI":"10.3390\/cancers15102732","article-title":"Targeting sphingosine 1-phosphate metabolism as a therapeutic avenue for prostate cancer","volume":"15","author":"Mebarek","year":"2023","journal-title":"Cancers"},{"issue":"5945","key":"10.1016\/j.canlet.2024.217286_bib51","doi-asserted-by":"crossref","first-page":"1254","DOI":"10.1126\/science.1176709","article-title":"Regulation of histone acetylation in the nucleus by sphingosine-1-phosphate","volume":"325","author":"Hait","year":"2009","journal-title":"Science (New York, N.Y.)"},{"issue":"2","key":"10.1016\/j.canlet.2024.217286_bib52","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.eururo.2023.04.021","article-title":"2022 update on prostate cancer epidemiology and risk factors-A systematic review","volume":"84","author":"Bergengren","year":"2023","journal-title":"Eur. Urol."},{"issue":"1\u20132","key":"10.1016\/j.canlet.2024.217286_bib53","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.ddstr.2011.02.004","article-title":"Novel androgen deprivation therapy (ADT) in the treatment of advanced prostate cancer","volume":"7","author":"Aragon-Ching","year":"2010","journal-title":"Drug Discov. Today Ther. Strat."},{"issue":"S1","key":"10.1016\/j.canlet.2024.217286_bib54","doi-asserted-by":"crossref","first-page":"S110","DOI":"10.1038\/modpathol.2017.158","article-title":"Treatment effects in prostate cancer","volume":"31","author":"Evans","year":"2018","journal-title":"Mod. Pathol. : Offic. J. United States and Canadian Acad. Pathol., Inc"},{"issue":"10","key":"10.1016\/j.canlet.2024.217286_bib55","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.6004\/jnccn.2023.0050","article-title":"Prostate cancer, version 4.2023, NCCN clinical Practice guidelines in oncology","volume":"21","author":"Schaeffer","year":"2023","journal-title":"J. Natl. Compr. Cancer Netw. : J. Natl. Compr. Cancer Netw."},{"key":"10.1016\/j.canlet.2024.217286_bib56","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1146\/annurev-med-051517-011947","article-title":"Treatment of advanced prostate cancer","volume":"70","author":"Teo","year":"2019","journal-title":"Annu. Rev. Med."},{"issue":"8","key":"10.1016\/j.canlet.2024.217286_bib57","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1016\/j.trecan.2020.04.010","article-title":"Advanced prostate cancer: treatment advances and future directions","volume":"6","author":"Swami","year":"2020","journal-title":"Trends in cancer"},{"issue":"8","key":"10.1016\/j.canlet.2024.217286_bib58","doi-asserted-by":"crossref","first-page":"1549","DOI":"10.1158\/1078-0432.CCR-21-4049","article-title":"Phase I\/II trial of enzalutamide and mifepristone, a glucocorticoid receptor antagonist, for metastatic castration-resistant prostate cancer","volume":"28","author":"Serritella","year":"2022","journal-title":"Clin. Cancer Res. : Offic. J. Am. Assoc. Cancer Res."},{"issue":"9","key":"10.1016\/j.canlet.2024.217286_bib59","doi-asserted-by":"crossref","DOI":"10.1210\/endocr\/bqab132","article-title":"Targeting glucocorticoid metabolism in prostate cancer","volume":"162","author":"Valle","year":"2021","journal-title":"Endocrinology"},{"issue":"3","key":"10.1016\/j.canlet.2024.217286_bib60","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.tem.2020.12.004","article-title":"Effects of medical treatment of prostate cancer on bone health","volume":"32","author":"Formenti","year":"2021","journal-title":"Trends Endocrinol. Metabol.: TEM"},{"issue":"5","key":"10.1016\/j.canlet.2024.217286_bib61","doi-asserted-by":"crossref","first-page":"866","DOI":"10.1016\/j.eururo.2014.06.042","article-title":"Impact of baseline corticosteroids on survival and steroid androgens in metastatic castration-resistant prostate cancer: exploratory analysis from COU-AA-301","volume":"67","author":"Montgomery","year":"2015","journal-title":"Eur. Urol."},{"issue":"7","key":"10.1016\/j.canlet.2024.217286_bib62","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1002\/pros.24324","article-title":"\u03b2Arrestin1 regulates glucocorticoid receptor mitogenic signaling in castration-resistant prostate cancer","volume":"82","author":"Purayil","year":"2022","journal-title":"Prostate"},{"issue":"10","key":"10.1016\/j.canlet.2024.217286_bib63","doi-asserted-by":"crossref","first-page":"970","DOI":"10.1056\/NEJMcibr1315706","article-title":"Steroid receptors aplenty in prostate cancer","volume":"370","author":"Sharifi","year":"2014","journal-title":"N. Engl. J. Med."},{"issue":"9","key":"10.1016\/j.canlet.2024.217286_bib64","doi-asserted-by":"crossref","first-page":"1461","DOI":"10.1038\/bjc.2015.133","article-title":"Stress hormones reduce the efficacy of paclitaxel in triple negative breast cancer through induction of DNA damage","volume":"112","author":"Reeder","year":"2015","journal-title":"Br. J. Cancer"},{"issue":"22","key":"10.1016\/j.canlet.2024.217286_bib65","doi-asserted-by":"crossref","first-page":"6163","DOI":"10.1158\/1078-0432.CCR-12-3826","article-title":"Glucocorticoid receptor antagonism as a novel therapy for triple-negative breast cancer","volume":"19","author":"Skor","year":"2013","journal-title":"Clin. Cancer Res. : Offic. J. Am. Assoc. Cancer Res."},{"issue":"8","key":"10.1016\/j.canlet.2024.217286_bib66","doi-asserted-by":"crossref","first-page":"1680","DOI":"10.1158\/1535-7163.MCT-16-0923","article-title":"Selective glucocorticoid receptor modulators (SGRMs) delay castrate-resistant prostate cancer growth","volume":"16","author":"Kach","year":"2017","journal-title":"Mol. Cancer Therapeut."},{"issue":"305","key":"10.1016\/j.canlet.2024.217286_bib67","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.aac7531","article-title":"Targeting the glucocorticoid receptor in breast and prostate cancers","volume":"7","author":"Kach","year":"2015","journal-title":"Sci. Transl. Med."},{"issue":"3","key":"10.1016\/j.canlet.2024.217286_bib68","doi-asserted-by":"crossref","first-page":"696","DOI":"10.7150\/jca.32497","article-title":"Emerging role of glucocorticoid receptor in castration resistant prostate cancer: a potential therapeutic target","volume":"11","author":"Kumar","year":"2020","journal-title":"J. Cancer"},{"issue":"595","key":"10.1016\/j.canlet.2024.217286_bib69","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.abe8226","article-title":"Hexose-6-phosphate dehydrogenase blockade reverses prostate cancer drug resistance in xenograft models by glucocorticoid inactivation","volume":"13","author":"Li","year":"2021","journal-title":"Sci. Transl. Med."},{"key":"10.1016\/j.canlet.2024.217286_bib70","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1016\/j.ejmech.2019.01.036","article-title":"Rational drug design for androgen receptor and glucocorticoids receptor dual antagonist","volume":"166","author":"Wu","year":"2019","journal-title":"Eur. J. Med. Chem."},{"issue":"4","key":"10.1016\/j.canlet.2024.217286_bib71","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1158\/1078-0432.CCR-17-0989","article-title":"The glucocorticoid receptor is a key player for prostate cancer cell survival and a target for improved antiandrogen therapy","volume":"24","author":"Puhr","year":"2018","journal-title":"Clin. Cancer Res. : Offic. J. Am. Assoc. Cancer Res."},{"issue":"10","key":"10.1016\/j.canlet.2024.217286_bib72","doi-asserted-by":"crossref","first-page":"2040","DOI":"10.1038\/s41388-019-1124-8","article-title":"Midkine (MDK) growth factor: a key player in cancer progression and a promising therapeutic target","volume":"39","author":"Filippou","year":"2020","journal-title":"Oncogene"},{"issue":"3","key":"10.1016\/j.canlet.2024.217286_bib73","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1038\/s41419-023-05760-w","article-title":"Matrix Gla Protein drives stemness and tumor initiation in ovarian cancer","volume":"14","author":"Nieddu","year":"2023","journal-title":"Cell Death Dis."},{"issue":"8","key":"10.1016\/j.canlet.2024.217286_bib74","doi-asserted-by":"crossref","first-page":"4702","DOI":"10.1093\/nar\/gkae229","article-title":"Protein G-quadruplex interactions and their effects on phase transitions and protein aggregation","volume":"52","author":"Sahoo","year":"2024","journal-title":"Nucleic Acids Res."},{"issue":"8","key":"10.1016\/j.canlet.2024.217286_bib75","doi-asserted-by":"crossref","first-page":"940","DOI":"10.1038\/s41590-021-00986-2","article-title":"Tpt1 the balance toward immunosuppression upon cell death","volume":"22","author":"Ma","year":"2021","journal-title":"Nat. Immunol."},{"issue":"1","key":"10.1016\/j.canlet.2024.217286_bib76","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.tcb.2012.10.002","article-title":"TPT1\/TCTP-regulated pathways in phenotypic reprogramming","volume":"23","author":"Amson","year":"2013","journal-title":"Trends Cell Biol."},{"issue":"11","key":"10.1016\/j.canlet.2024.217286_bib77","doi-asserted-by":"crossref","first-page":"1961","DOI":"10.1016\/j.cmet.2023.09.009","article-title":"High dietary fructose promotes hepatocellular carcinoma progression by enhancing O-GlcNAcylation via microbiota-derived acetate","volume":"35","author":"Zhou","year":"2023","journal-title":"Cell Metabol."},{"issue":"1","key":"10.1016\/j.canlet.2024.217286_bib78","doi-asserted-by":"crossref","first-page":"3420","DOI":"10.1038\/s41467-020-17243-z","article-title":"EEF1A1 deacetylation enables transcriptional activation of remyelination","volume":"11","author":"Duman","year":"2020","journal-title":"Nat. Commun."},{"issue":"24","key":"10.1016\/j.canlet.2024.217286_bib79","doi-asserted-by":"crossref","first-page":"16484","DOI":"10.1021\/acs.jmedchem.3c00963","article-title":"Development of MPS1 inhibitors: recent advances and perspectives","volume":"66","author":"Zeng","year":"2023","journal-title":"J. Med. Chem."},{"issue":"10","key":"10.1016\/j.canlet.2024.217286_bib80","doi-asserted-by":"crossref","first-page":"1128","DOI":"10.1016\/j.ccell.2022.08.015","article-title":"MPS1 inhibition primes immunogenicity of KRAS-LKB1 mutant lung cancer","volume":"40","author":"Kitajima","year":"2022","journal-title":"Cancer Cell"},{"issue":"1","key":"10.1016\/j.canlet.2024.217286_bib81","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.cmet.2020.10.012","article-title":"Metabolic-pathway-based subtyping of triple-negative breast cancer reveals potential therapeutic targets","volume":"33","author":"Gong","year":"2021","journal-title":"Cell Metabol."},{"issue":"5","key":"10.1016\/j.canlet.2024.217286_bib82","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1038\/sj.cdd.4401196","article-title":"Caspase-mediated cleavage of the U snRNP-associated Sm-F protein during apoptosis","volume":"10","author":"Malmegrim de Farias","year":"2003","journal-title":"Cell Death Differ."},{"issue":"7","key":"10.1016\/j.canlet.2024.217286_bib83","doi-asserted-by":"crossref","first-page":"2247","DOI":"10.1158\/0008-5472.CAN-12-2501","article-title":"Targeting the deregulated spliceosome core machinery in cancer cells triggers mTOR blockade and autophagy","volume":"73","author":"Quidville","year":"2013","journal-title":"Cancer Res."},{"issue":"34","key":"10.1016\/j.canlet.2024.217286_bib84","doi-asserted-by":"crossref","first-page":"5342","DOI":"10.1038\/s41388-021-01932-0","article-title":"CRIP1 cooperates with BRCA2 to drive the nuclear enrichment of RAD51 and to facilitate homologous repair upon DNA damage induced by chemotherapy","volume":"40","author":"Sun","year":"2021","journal-title":"Oncogene"},{"key":"10.1016\/j.canlet.2024.217286_bib85","doi-asserted-by":"crossref","DOI":"10.1016\/j.ebiom.2023.104961","article-title":"CRIP1 involves the pathogenesis of multiple myeloma via dual-regulation of proteasome and autophagy","volume":"100","author":"Tang","year":"2024","journal-title":"EBioMedicine"},{"issue":"26","key":"10.1016\/j.canlet.2024.217286_bib86","doi-asserted-by":"crossref","DOI":"10.1002\/advs.202303246","article-title":"CRIP1 reshapes the gastric cancer microenvironment to facilitate development of lymphatic metastasis","volume":"10","author":"Wu","year":"2023","journal-title":"Adv. Sci."},{"issue":"12","key":"10.1016\/j.canlet.2024.217286_bib87","doi-asserted-by":"crossref","first-page":"2329","DOI":"10.1136\/gutjnl-2022-329349","article-title":"CRIP1 fosters MDSC trafficking and resets tumour microenvironment via facilitating NF-\u03baB\/p65 nuclear translocation in pancreatic ductal adenocarcinoma","volume":"72","author":"Liu","year":"2023","journal-title":"Gut"},{"issue":"5","key":"10.1016\/j.canlet.2024.217286_bib88","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1016\/j.cell.2011.02.013","article-title":"Hallmarks of cancer: the next generation","volume":"144","author":"Hanahan","year":"2011","journal-title":"Cell"},{"key":"10.1016\/j.canlet.2024.217286_bib89","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.canlet.2021.10.034","article-title":"Wnt signaling pathway in cancer immunotherapy","volume":"525","author":"Zhou","year":"2022","journal-title":"Cancer Lett."},{"key":"10.1016\/j.canlet.2024.217286_bib90","doi-asserted-by":"crossref","DOI":"10.1016\/j.canlet.2023.216143","article-title":"EZH2 and NF-\u03baB: a context-dependent crosstalk and transcriptional regulation in cancer","volume":"560","author":"Kaur","year":"2023","journal-title":"Cancer Lett."},{"key":"10.1016\/j.canlet.2024.217286_bib91","doi-asserted-by":"crossref","DOI":"10.1016\/j.canlet.2023.216094","article-title":"Lymphocyte antigen 6K signaling to aurora kinase promotes advancement of the cell cycle and the growth of cancer cells, which is inhibited by LY6K-NSC243928 interaction","volume":"558","author":"Selvanesan","year":"2023","journal-title":"Cancer Lett."},{"issue":"5","key":"10.1016\/j.canlet.2024.217286_bib92","article-title":"Role of cell division cycle-associated proteins in regulating cell cycle and promoting tumor progression","volume":"1879","author":"Wang","year":"2024","journal-title":"Biochim. Biophys. Acta Rev. Canc"},{"issue":"6","key":"10.1016\/j.canlet.2024.217286_bib93","doi-asserted-by":"crossref","first-page":"R141","DOI":"10.1530\/ERC-20-0517","article-title":"Novel insights in cell cycle dysregulation during prostate cancer progression","volume":"28","author":"Ben-Salem","year":"2021","journal-title":"Endocr. Relat. Cancer"},{"key":"10.1016\/j.canlet.2024.217286_bib94","doi-asserted-by":"crossref","DOI":"10.1016\/j.canlet.2023.216243","article-title":"Exosomal delivery of cannabinoids against cancer","volume":"566","author":"Kaur","year":"2023","journal-title":"Cancer Lett."},{"issue":"48","key":"10.1016\/j.canlet.2024.217286_bib95","doi-asserted-by":"crossref","first-page":"5481","DOI":"10.1038\/onc.2013.83","article-title":"Targeting cell cycle and hormone receptor pathways in cancer","volume":"32","author":"Comstock","year":"2013","journal-title":"Oncogene"},{"key":"10.1016\/j.canlet.2024.217286_bib96","doi-asserted-by":"crossref","DOI":"10.1016\/j.canlet.2023.216464","article-title":"SETD4 inhibits prostate cancer development by promoting H3K27me3-mediated NUPR1 transcriptional repression and cell cycle arrest","volume":"579","author":"Wang","year":"2023","journal-title":"Cancer Lett."},{"key":"10.1016\/j.canlet.2024.217286_bib97","doi-asserted-by":"crossref","DOI":"10.1016\/j.canlet.2022.216046","article-title":"SB226, an inhibitor of tubulin polymerization, inhibits paclitaxel-resistant melanoma growth and spontaneous metastasis","volume":"555","author":"Deng","year":"2023","journal-title":"Cancer Lett."},{"issue":"1","key":"10.1016\/j.canlet.2024.217286_bib98","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1038\/nrc.2017.96","article-title":"Sphingolipid metabolism in cancer signalling and therapy","volume":"18","author":"Ogretmen","year":"2018","journal-title":"Nat. Rev. Cancer"},{"issue":"9","key":"10.1016\/j.canlet.2024.217286_bib99","doi-asserted-by":"crossref","DOI":"10.1002\/ctm2.1056","article-title":"Sphingosine 1-phosphate lyase facilitates cancer progression through converting sphingolipids to glycerophospholipids","volume":"12","author":"Uranbileg","year":"2022","journal-title":"Clin. Transl. Med."}],"container-title":["Cancer Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304383524006815?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304383524006815?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,11,10]],"date-time":"2024-11-10T20:44:36Z","timestamp":1731271476000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0304383524006815"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11]]},"references-count":99,"alternative-id":["S0304383524006815"],"URL":"https:\/\/doi.org\/10.1016\/j.canlet.2024.217286","relation":{},"ISSN":["0304-3835"],"issn-type":[{"value":"0304-3835","type":"print"}],"subject":[],"published":{"date-parts":[[2024,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Evaluation of glucocorticoid-related genes reveals GPD1 as a therapeutic target and regulator of sphingosine 1-phosphate metabolism in CRPC","name":"articletitle","label":"Article Title"},{"value":"Cancer Letters","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.canlet.2024.217286","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"217286"}}