{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T06:52:46Z","timestamp":1761807166513,"version":"build-2065373602"},"reference-count":56,"publisher":"Elsevier BV","issue":"6-7","license":[{"start":{"date-parts":[[2005,11,1]],"date-time":"2005-11-01T00:00:00Z","timestamp":1130803200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2005,11,1]],"date-time":"2005-11-01T00:00:00Z","timestamp":1130803200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.fr","em-consulte.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cancer\/Radioth\u00e9rapie"],"published-print":{"date-parts":[[2005,11]]},"DOI":"10.1016\/j.canrad.2005.07.004","type":"journal-article","created":{"date-parts":[[2005,9,16]],"date-time":"2005-09-16T12:40:21Z","timestamp":1126874421000},"page":"351-357","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"title":["Tumeurs \u00e9pith\u00e9liales thymiques"],"prefix":"10.1016","volume":"9","author":[{"given":"C.","family":"Le P\u00e9choux","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Mah\u00e9","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.-J.","family":"Bretel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Roberti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Ruffi\u00e9","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.canrad.2005.07.004_bib1","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1002\/(SICI)1096-9098(199609)63:1<17::AID-JSO4>3.0.CO;2-T","article-title":"Preoperative radiotherapy and surgery for advanced thymoma with invasion to the great vessels","volume":"63","author":"Akaogi","year":"1996","journal-title":"J. Surg. Oncol."},{"key":"10.1016\/j.canrad.2005.07.004_bib2","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/0277-5379(84)90036-1","article-title":"Invasive carcinoma of the thymus. A multicentric retrospective review of 56 cases","volume":"20","author":"Arriagada","year":"1984","journal-title":"Eur. J. Cancer Clin. Oncol."},{"key":"10.1016\/j.canrad.2005.07.004_bib3","series-title":"7th cancer research workshop","article-title":"Staging and preliminary results of the Thymic Tumour Study Group","author":"Bretel","year":"1989"},{"key":"10.1016\/j.canrad.2005.07.004_bib4","doi-asserted-by":"crossref","first-page":"1484","DOI":"10.1200\/JCO.1994.12.7.1484","article-title":"Prognostic factors and outcome of incompletely resected invasive thymoma following radiation therapy","volume":"12","author":"Ciernik","year":"1994","journal-title":"J. Clin. Oncol."},{"key":"10.1016\/j.canrad.2005.07.004_bib5","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/S0022-5223(19)37426-4","article-title":"Management of patients with malignant thymoma","volume":"87","author":"Cohen","year":"1984","journal-title":"J. Thorac. Cardiovasc. Surg."},{"key":"10.1016\/j.canrad.2005.07.004_bib6","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/0167-8140(94)01493-M","article-title":"Thymoma results of a multicentric retrospective series of 149 non-metastatic irradiated patients and review of the literature","volume":"34","author":"Cowen","year":"1995","journal-title":"Radiother. Oncol."},{"key":"10.1016\/j.canrad.2005.07.004_bib7","doi-asserted-by":"crossref","first-page":"1722","DOI":"10.1200\/JCO.1988.6.11.1722","article-title":"Invasive thymoma: the role of mediastinal irradiation following complete or incomplete surgical resection","volume":"6","author":"Curran","year":"1988","journal-title":"J. Clin. Oncol."},{"key":"10.1016\/j.canrad.2005.07.004_bib8","doi-asserted-by":"crossref","first-page":"1860","DOI":"10.1016\/j.athoracsur.2003.10.001","article-title":"Thymic tumors","volume":"77","author":"Detterbeck","year":"2004","journal-title":"Ann. Thorac. Surg."},{"key":"10.1016\/j.canrad.2005.07.004_bib9","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1016\/S1052-3359(25)00581-2","article-title":"The radiotherapeutic management of invasive thymomas","volume":"11","author":"Dziuba","year":"2001","journal-title":"Chest Surg. Clin. N. Am."},{"key":"10.1016\/j.canrad.2005.07.004_bib10","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1016\/j.ijrobp.2003.11.021","article-title":"Thymic carcinoma: state of the art review","volume":"59","author":"Eng","year":"2004","journal-title":"Int. J. Radiat. Oncol. Phys."},{"key":"10.1016\/j.canrad.2005.07.004_bib11","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1002\/ijc.11099","article-title":"Malignant thymoma in the Unites States: demographic patterns in incidence and associations with subsequent malignancies","volume":"105","author":"Engels","year":"2003","journal-title":"Int. J. Cancer"},{"key":"10.1016\/j.canrad.2005.07.004_bib12","doi-asserted-by":"crossref","first-page":"1871","DOI":"10.1002\/(SICI)1097-0142(19990501)85:9<1871::AID-CNCR1>3.0.CO;2-Y","article-title":"Non-surgical management of malignant thymoma","volume":"85","author":"Hejna","year":"1999","journal-title":"Cancer"},{"key":"10.1016\/j.canrad.2005.07.004_bib13","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/0167-8140(91)90078-U","article-title":"Postoperative radiotherapy in invasive thymoma","volume":"21","author":"Jackson","year":"1991","journal-title":"Radiother. Oncol."},{"key":"10.1016\/j.canrad.2005.07.004_bib14","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1634\/theoncologist.6-3-239","article-title":"Thymoma: update for the new millenium","volume":"6","author":"Johnson","year":"2001","journal-title":"The Oncologist"},{"key":"10.1016\/j.canrad.2005.07.004_bib15","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/j.lungcan.2003.12.010","article-title":"Phase II study of a multidisciplinary approach with induction chemotherapy, followed by surgical resection, radiation therapy and consolidation chemotherapy for unresectable malignant thymomas: final report","volume":"44","author":"Kim","year":"2004","journal-title":"Lung Cancer"},{"key":"10.1016\/j.canrad.2005.07.004_bib16","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1016\/0003-4975(90)90300-U","article-title":"Reoperation for thymoma: report of 23 cases","volume":"49","author":"Kirschner","year":"1990","journal-title":"Ann. Thorac. Surg."},{"key":"10.1016\/j.canrad.2005.07.004_bib17","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1055\/s-2007-1013679","article-title":"Coronary artery disease and aortic valve disease as a long-term sequel of mediastinal and thoracic irradiation","volume":"45","author":"Kleikamp","year":"1997","journal-title":"J. Thorac. Cardiovasc. Surg."},{"key":"10.1016\/j.canrad.2005.07.004_bib18","doi-asserted-by":"crossref","first-page":"878","DOI":"10.1016\/S0003-4975(03)00555-1","article-title":"Therapy for thymic epithelial tumors: a clinical study of 1320 patients from Japan","volume":"76","author":"Kondo","year":"2003","journal-title":"Ann. Thorac. Surg."},{"key":"10.1016\/j.canrad.2005.07.004_bib19","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.1016\/j.athoracsur.2003.07.042","article-title":"WHO histologic classification is a prognostic indicator in thymoma","volume":"77","author":"Kondo","year":"2004","journal-title":"Ann. Thorac. Surg."},{"key":"10.1016\/j.canrad.2005.07.004_bib20","first-page":"634","article-title":"In vivo detection of malignant thymic masses by indium-111-DTPA-D-Phe1-octreotide scintigraphy","volume":"39","author":"Lastoria","year":"1998","journal-title":"J. Nucl. Med."},{"key":"10.1016\/j.canrad.2005.07.004_bib21","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1016\/S0046-8177(78)80131-2","article-title":"Thymic hyperplasia and neoplasia: a review of current concepts","volume":"9","author":"Levine","year":"1978","journal-title":"Hum. Pathol."},{"key":"10.1016\/j.canrad.2005.07.004_bib22","doi-asserted-by":"crossref","first-page":"2010","DOI":"10.1002\/1097-0142(20010601)91:11<2010::AID-CNCR1226>3.0.CO;2-2","article-title":"Combined etoposide, ifosfamide, and cisplatin in the treatment of patients with advanced thymoma and thymic carcinoma","volume":"91","author":"Loehrer","year":"2001","journal-title":"Cancer"},{"key":"10.1016\/j.canrad.2005.07.004_bib23","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1200\/JCO.2004.02.047","article-title":"Octreotide alone or with prednisone in patients with advanced thymoma and thymic carcinoma: an eastern cooperative oncology group phase II trial","volume":"22","author":"Loehrer","year":"2004","journal-title":"J. Clin. Oncol."},{"key":"10.1016\/j.canrad.2005.07.004_bib24","doi-asserted-by":"crossref","first-page":"706","DOI":"10.1002\/1097-0142(19910815)68:4<706::AID-CNCR2820680407>3.0.CO;2-H","article-title":"Neoadjuvant chemotherapy, surgery and postoperative radiation therapy for invasive thymoma","volume":"68","author":"Macchiarini","year":"1991","journal-title":"Cancer"},{"key":"10.1016\/j.canrad.2005.07.004_bib25","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1016\/0003-4975(91)90478-9","article-title":"Thymoma: results of 241 operated cases","volume":"51","author":"Maggi","year":"1991","journal-title":"Ann. Thorac. Surg."},{"key":"10.1016\/j.canrad.2005.07.004_bib26","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1016\/S0003-4975(02)03828-6","article-title":"Adjuvant radiation therapy for stage II thymoma","volume":"74","author":"Mangi","year":"2002","journal-title":"Ann. Thorac. Surg."},{"key":"10.1016\/j.canrad.2005.07.004_bib27","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1007\/BF00737071","article-title":"Thymoma and thymic carcinoma. Relation of thymoma epithelial cells to the cortical and medullary differentiation of thymus","volume":"407","author":"Marino","year":"1985","journal-title":"Virchows Arch. A Pathol. Anat. Histopathol."},{"key":"10.1016\/j.canrad.2005.07.004_bib28","doi-asserted-by":"crossref","first-page":"2485","DOI":"10.1002\/1097-0142(19811201)48:11<2485::AID-CNCR2820481123>3.0.CO;2-R","article-title":"Follow-up study of thymomas with special reference to their clinical stages","volume":"48","author":"Masaoka","year":"1981","journal-title":"Cancer"},{"key":"10.1016\/j.canrad.2005.07.004_bib29","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/S0003-4975(10)62558-1","article-title":"Recurrence of thymoma: clinicopathological features, therapy and prognosis","volume":"39","author":"Monden","year":"1985","journal-title":"Ann. Thor. Surg."},{"key":"10.1016\/j.canrad.2005.07.004_bib30","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S0167-8140(03)00003-3","article-title":"Dose-volume analysis of lung complications in the radiation treatment of malignant thymoma: a retrospective review","volume":"67","author":"Moiseenko","year":"2003","journal-title":"Radiother. Oncol."},{"key":"10.1016\/j.canrad.2005.07.004_bib31","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1016\/0360-3016(95)00079-E","article-title":"Radiotherapy and chemotherapy for invasive thymomas: a multicentric retrospective review of 90 cases. The FNCLCC trialists. F\u00e9d\u00e9ration nationale des centres de lutte contre le cancer","volume":"32","author":"Mornex","year":"1995","journal-title":"Int. J. Radiat. Oncol. Biol. Phys."},{"key":"10.1016\/j.canrad.2005.07.004_bib32","doi-asserted-by":"crossref","first-page":"1134","DOI":"10.1016\/S0022-5223(03)00798-0","article-title":"Thymoma: a clinicopathologic study based on the new World Health Organization classification","volume":"126","author":"Nakagawa","year":"2003","journal-title":"J. Thorac. Cardiovasc. Surg."},{"key":"10.1016\/j.canrad.2005.07.004_bib33","doi-asserted-by":"crossref","first-page":"1041","DOI":"10.1016\/S0022-5223(19)35673-9","article-title":"Thymoma: results with complete resection and adjuvant postoperative irradiation in 141 consecutive patients","volume":"95","author":"Nakahara","year":"1988","journal-title":"J. Thorac. Cardiovasc. Surg."},{"key":"10.1016\/j.canrad.2005.07.004_bib34","doi-asserted-by":"crossref","first-page":"1405","DOI":"10.1002\/cncr.10373","article-title":"Postoperative radiotherapy for patients with completely resected thymoma. A multi-institutional retrospective review of 103 patients","volume":"94","author":"Ogawa","year":"2002","journal-title":"Cancer"},{"key":"10.1016\/j.canrad.2005.07.004_bib35","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1056\/NEJM199701233360405","article-title":"Successful treatment of a patient with a thymoma and pure red cell aplasia with octreotide and prednisone","volume":"336","author":"Palmieri","year":"1997","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.canrad.2005.07.004_bib36","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1016\/0003-4975(90)90185-9","article-title":"Analysis of prognostic factors and clinicopathological staging of thymoma","volume":"50","author":"Pescarmona","year":"1990","journal-title":"Ann. Thorac. Surg."},{"key":"10.1016\/j.canrad.2005.07.004_bib37","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1016\/0360-3016(92)90911-Z","article-title":"Thymoma: treatment and prognosis","volume":"23","author":"Pollack","year":"1992","journal-title":"Int. J. Radiat. Oncol. Biol. Phys."},{"key":"10.1016\/j.canrad.2005.07.004_bib38","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1016\/S0022-5223(96)70265-9","article-title":"Prognostic factors and long-term results after thymoma resection: a series of 307 patients","volume":"112","author":"Regnard","year":"1996","journal-title":"J. Thorac. Cardiovasc. Surg."},{"key":"10.1016\/j.canrad.2005.07.004_bib39","doi-asserted-by":"crossref","first-page":"1593","DOI":"10.1016\/S0003-4975(97)01175-2","article-title":"Results of re-resection for recurrent thymomas","author":"Regnard","year":"1997","journal-title":"Ann. Thorac. Surg."},{"key":"10.1016\/j.canrad.2005.07.004_bib40","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1016\/0924-4212(96)81491-5","article-title":"Radioth\u00e9rapie des thymomes. \u00c9tude de la litt\u00e9rature \u00e0 propos d\u2019une s\u00e9rie r\u00e9trospective et multicentrique de 149 cas","volume":"82","author":"Resbeut","year":"1995","journal-title":"Bull. Cancer Radiother."},{"key":"10.1016\/j.canrad.2005.07.004_bib41","series-title":"WHO international classification of tumours","first-page":"65","article-title":"Histological typing of tumours of the thymus","author":"Rosai","year":"1999"},{"key":"10.1016\/j.canrad.2005.07.004_bib42","first-page":"365","article-title":"Standards, options et recommandations pour la prise en charge des patients atteints de tumeurs \u00e9pith\u00e9liales du thymus","volume":"86","author":"Ruffi\u00e9","year":"1999","journal-title":"Bull. Cancer"},{"key":"10.1016\/j.canrad.2005.07.004_bib43","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/S0022-5223(97)70399-4","article-title":"Recurrence of thymoma: analysis of clinicopathologic features, treatment and outcome","volume":"113","author":"Ruffini","year":"1997","journal-title":"J. Thorac. Cardiovasc. Surg."},{"key":"10.1016\/j.canrad.2005.07.004_bib44","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1159\/000029361","article-title":"Invasive thymoma with long-term survival by extensive re-operation","volume":"66","author":"Sakada","year":"1999","journal-title":"Respiration"},{"key":"10.1016\/j.canrad.2005.07.004_bib45","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1034\/j.1600-0455.2002.430306.x","article-title":"Differential diagnosis between thymoma and non-thymoma by dynamic MR imaging","volume":"43","author":"Sakai","year":"2002","journal-title":"Acta Radiol."},{"key":"10.1016\/j.canrad.2005.07.004_bib46","first-page":"1595","article-title":"Differential diagnosis of thymic tumors using a combination of 11C-methionine PET and FDG PET","volume":"40","author":"Sasaki","year":"1999","journal-title":"J. Nucl. Med."},{"key":"10.1016\/j.canrad.2005.07.004_bib47","doi-asserted-by":"crossref","first-page":"1635","DOI":"10.1016\/S0003-4975(03)00819-1","article-title":"Comparison of stages I-II thymoma treated by complete resection with or without adjuvant radiation","volume":"76","author":"Singhal","year":"2003","journal-title":"Ann. Thorac. Surg."},{"key":"10.1016\/j.canrad.2005.07.004_bib48","first-page":"37","article-title":"Thymoma: a review of the clinical and pathological findings in 65 cases","volume":"46","author":"Sperling","year":"2003","journal-title":"Can. J. Surg."},{"key":"10.1016\/j.canrad.2005.07.004_bib49","doi-asserted-by":"crossref","first-page":"1501","DOI":"10.1200\/JCO.2004.10.113","article-title":"Tumor recurrence and survival in patients treated for thymomas and thymic squamous-cell carcinomas: a retrospective analysis","volume":"22","author":"Strobel","year":"2004","journal-title":"J. Clin. Oncol."},{"key":"10.1016\/j.canrad.2005.07.004_bib50","doi-asserted-by":"crossref","first-page":"2280","DOI":"10.1200\/JCO.1999.17.7.2280","article-title":"Thymoma: state of the art","volume":"17","author":"Thomas","year":"1999","journal-title":"J. Clin. Oncol."},{"key":"10.1016\/j.canrad.2005.07.004_bib51","doi-asserted-by":"crossref","first-page":"881","DOI":"10.2214\/ajr.179.4.1790881","article-title":"Using the WHO classification of thymic epithelial neoplasms to describe CT findings","volume":"179","author":"Tomiyama","year":"2002","journal-title":"Am. J. Roentgenol."},{"key":"10.1016\/j.canrad.2005.07.004_bib52","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/0360-3016(96)00086-7","article-title":"Entire hemithorax irradiation following complete resection in patients with stages II\u2013III invasive thymoma","volume":"35","author":"Uematsu","year":"1996","journal-title":"Int. J. Radiat. Oncol. Biol. Phys."},{"key":"10.1016\/j.canrad.2005.07.004_bib53","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/0167-8140(90)90154-O","article-title":"Role of radiation therapy in locally advanced thymoma","volume":"19","author":"Urgesi","year":"1990","journal-title":"Radiother. Oncol."},{"key":"10.1016\/j.canrad.2005.07.004_bib54","doi-asserted-by":"crossref","first-page":"1014","DOI":"10.1016\/S0003-4975(98)00082-4","article-title":"Surgical management of radiation induced heart disease","volume":"65","author":"Veeragandam","year":"1998","journal-title":"Ann. Thorac. Surg."},{"key":"10.1016\/j.canrad.2005.07.004_bib55","doi-asserted-by":"crossref","first-page":"1866","DOI":"10.1016\/S0003-4975(03)01020-8","article-title":"Long-term outcome after multimodality treatment for stage III thymic tumors","volume":"76","author":"Venuta","year":"2003","journal-title":"Ann. Thorac. Surg."},{"key":"10.1016\/j.canrad.2005.07.004_bib56","doi-asserted-by":"crossref","first-page":"1074","DOI":"10.1002\/1097-0142(19850301)55:5<1074::AID-CNCR2820550524>3.0.CO;2-T","article-title":"Thymoma, a comparative study of clinical features, histologic features and survival in 200 cases","volume":"55","author":"Verley","year":"1985","journal-title":"Cancer"}],"container-title":["Cancer\/Radioth\u00e9rapie"],"original-title":[],"language":"fr","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1278321805001071?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1278321805001071?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T12:11:59Z","timestamp":1761135119000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1278321805001071"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,11]]},"references-count":56,"journal-issue":{"issue":"6-7","published-print":{"date-parts":[[2005,11]]}},"alternative-id":["S1278321805001071"],"URL":"https:\/\/doi.org\/10.1016\/j.canrad.2005.07.004","relation":{},"ISSN":["1278-3218"],"issn-type":[{"type":"print","value":"1278-3218"}],"subject":[],"published":{"date-parts":[[2005,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Tumeurs \u00e9pith\u00e9liales thymiques","name":"articletitle","label":"Article Title"},{"value":"Cancer\/Radioth\u00e9rapie","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.canrad.2005.07.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2005 Elsevier SAS. All rights reserved.","name":"copyright","label":"Copyright"}]}}