{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T00:15:31Z","timestamp":1761178531910,"version":"build-2065373602"},"reference-count":37,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2020,2,1]],"date-time":"2020-02-01T00:00:00Z","timestamp":1580515200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,2,1]],"date-time":"2020-02-01T00:00:00Z","timestamp":1580515200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.fr","em-consulte.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cancer\/Radioth\u00e9rapie"],"published-print":{"date-parts":[[2020,2]]},"DOI":"10.1016\/j.canrad.2019.06.015","type":"journal-article","created":{"date-parts":[[2020,1,25]],"date-time":"2020-01-25T16:47:58Z","timestamp":1579970878000},"page":"38-43","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Quel impact de la RCMI des carcinomes nasopharyng\u00e9s sur les structures glandulaires\u00a0?"],"prefix":"10.1016","volume":"24","author":[{"given":"W.","family":"Mnejja","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Daoud","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.","family":"Fourati","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Sahnoun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W.","family":"Siala","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Farhat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Daoud","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.canrad.2019.06.015_bib0005","doi-asserted-by":"crossref","DOI":"10.1002\/14651858.CD004329.pub2","article-title":"Chemotherapy as an adjunct to radiotherapy in locally advanced nasopharyngeal carcinoma","author":"Baujat","year":"2006","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.canrad.2019.06.015_bib0010","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1016\/S1470-2045(15)70126-9","article-title":"Chemotherapy and radiotherapy in nasopharyngeal carcinoma: an update of the MAC-NPC meta-analysis","volume":"16","author":"Blanchard","year":"2015","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.canrad.2019.06.015_bib0015","doi-asserted-by":"crossref","first-page":"1509","DOI":"10.1016\/S1470-2045(16)30410-7","article-title":"Induction chemotherapy plus concurrent chemoradiotherapy versus concurrent chemoradiotherapy alone in locoregionally advanced nasopharyngeal carcinoma: a phase 3, multicentre, randomised controlled trial","volume":"17","author":"Sun","year":"2016","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.canrad.2019.06.015_bib0020","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.ejca.2016.12.039","article-title":"Neoadjuvant chemotherapy followed by concurrent chemoradiotherapy versus concurrent chemoradiotherapy alone in locoregionally advanced nasopharyngeal carcinoma: a phase III multicentre randomised controlled trial","volume":"75","author":"Cao","year":"2017","journal-title":"Eur J Cancer"},{"key":"10.1016\/j.canrad.2019.06.015_bib0025","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.canrad.2018.03.010","article-title":"Apports et limites de la r\u00e9irradiation conformationnelle avec modulation d\u2019intensit\u00e9 des carcinomes nasopharyng\u00e9s","volume":"23","author":"Farhat","year":"2019","journal-title":"Cancer Radiother"},{"key":"10.1016\/j.canrad.2019.06.015_bib0030","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/j.anl.2008.04.006","article-title":"Late complications of radiotherapy for nasopharyngeal carcinoma","volume":"36","author":"Sumitsawan","year":"2009","journal-title":"Auris Nasus Larynx"},{"key":"10.1016\/j.canrad.2019.06.015_bib0035","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2014\/268340","article-title":"Late toxicities after conventional radiotherapy for nasopharyngeal carcinoma: incidence and risk factors","volume":"2014","author":"Siala","year":"2014","journal-title":"J Radiother"},{"key":"10.1016\/j.canrad.2019.06.015_bib0040","doi-asserted-by":"crossref","first-page":"1121","DOI":"10.1016\/j.ijrobp.2008.05.023","article-title":"Major late toxicities after conformal radiotherapy for nasopharyngeal carcinoma\u00a0\u2013\u00a0patient\u00a0\u2013\u00a0and treatment-related risk factors","volume":"73","author":"Lee","year":"2009","journal-title":"Int J Radiat Oncol"},{"key":"10.1016\/j.canrad.2019.06.015_bib0045","doi-asserted-by":"crossref","first-page":"2587","DOI":"10.1016\/j.ejca.2015.08.006","article-title":"Intensity-modulated radiotherapy prolongs the survival of patients with nasopharyngeal carcinoma compared with conventional two-dimensional radiotherapy: a 10-year experience with a large cohort and long follow-up","volume":"51","author":"Zhang","year":"2015","journal-title":"Eur J Cancer"},{"key":"10.1016\/j.canrad.2019.06.015_bib0050","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1016\/j.radonc.2012.08.013","article-title":"A prospective, randomized study comparing outcomes and toxicities of intensity-modulated radiotherapy vs. conventional two-dimensional radiotherapy for the treatment of nasopharyngeal carcinoma","volume":"104","author":"Peng","year":"2012","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.canrad.2019.06.015_bib0055","doi-asserted-by":"crossref","first-page":"960","DOI":"10.1016\/j.ijrobp.2003.12.024","article-title":"Quantification of volumetric and geometric changes occurring during fractionated radiotherapy for head-and-neck cancer using an integrated CT\/linear accelerator system","volume":"59","author":"Barker","year":"2004","journal-title":"Int J Radiat Oncol"},{"key":"10.1016\/j.canrad.2019.06.015_bib0060","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.semradonc.2009.11.001","article-title":"Adaptive radiotherapy: merging principle into clinical practice","volume":"20","author":"Yan","year":"2010","journal-title":"Semin Radiat Oncol"},{"key":"10.1016\/j.canrad.2019.06.015_bib0065","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/j.radonc.2011.10.009","article-title":"The seventh edition of the UICC\/AJCC staging system for nasopharyngeal carcinoma is prognostically useful for patients treated with intensity-modulated radiotherapy from an endemic area in China","volume":"104","author":"Chen","year":"2012","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.canrad.2019.06.015_bib0070","doi-asserted-by":"crossref","first-page":"S104","DOI":"10.1016\/j.canrad.2016.07.031","article-title":"Radioth\u00e9rapie des cancers du nasopharynx","volume":"20","author":"Maingon","year":"2016","journal-title":"Cancer Radiother"},{"key":"10.1016\/j.canrad.2019.06.015_bib0075","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.radonc.2017.10.032","article-title":"International guideline for the delineation of the clinical target volumes (CTV) for nasopharyngeal carcinoma","volume":"126","author":"Lee","year":"2018","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.canrad.2019.06.015_bib0080","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1016\/S1278-3218(01)00117-2","article-title":"D\u00e9finition des volumes en radioth\u00e9rapie externe\u00a0: rapports ICRU 50\u00a0et 62","volume":"5","author":"Chavaudra","year":"2001","journal-title":"Cancer Radiother"},{"key":"10.1016\/j.canrad.2019.06.015_bib0085","unstructured":"International Commission on Radiation Units and Measurements (ICRU). Disponible sur\u00a0: https:\/\/icru.org\/testing\/reports\/prescribing-recording-and-reporting-intensity-modulated-photon-beam-therapy-imrt-icru-report-83."},{"key":"10.1016\/j.canrad.2019.06.015_bib0090","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.radonc.2015.07.041","article-title":"CT-based delineation of organs at risk in the head and neck region: DAHANCA, EORTC, GORTEC, HKNPCSG, NCIC CTG, NCRI, NRG Oncology and TROG consensus guidelines","volume":"117","author":"Brouwer","year":"2015","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.canrad.2019.06.015_bib0095","doi-asserted-by":"crossref","first-page":"S36","DOI":"10.1016\/j.canrad.2016.07.032","article-title":"D\u00e9lin\u00e9ation des organes \u00e0 risque et contraintes dosim\u00e9triques","volume":"20","author":"No\u00ebl","year":"2016","journal-title":"Cancer Radiother"},{"key":"10.1016\/j.canrad.2019.06.015_bib0100","doi-asserted-by":"crossref","first-page":"1121","DOI":"10.1016\/j.ijrobp.2007.01.030","article-title":"Spatial and dosimetric variability of organs at risk in head-and-neck intensity-modulated radiotherapy","volume":"68","author":"Robar","year":"2007","journal-title":"Int J Radiat Oncol"},{"key":"10.1016\/j.canrad.2019.06.015_bib0105","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1016\/j.meddos.2013.01.007","article-title":"A quantitative assessment of volumetric and anatomic changes of the parotid gland during intensity-modulated radiotherapy for head and neck cancer using serial computed tomography","volume":"38","author":"Ajani","year":"2013","journal-title":"Med Dosim"},{"key":"10.1016\/j.canrad.2019.06.015_bib0110","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1093\/jrr\/rrt103","article-title":"Developing an adaptive radiation therapy strategy for nasopharyngeal carcinoma","volume":"55","author":"Fung","year":"2014","journal-title":"J Radiat Res (Tokyo)"},{"key":"10.1016\/j.canrad.2019.06.015_bib0115","doi-asserted-by":"crossref","first-page":"46","DOI":"10.2152\/jmi.60.46","article-title":"Changes of tumor and normal structures of the neck during radiation therapy for head and neck cancer requires adaptive strategy","volume":"60","author":"Bando","year":"2013","journal-title":"J Med Invest"},{"key":"10.1016\/j.canrad.2019.06.015_bib0120","article-title":"A prospective study of weekly intensity modulated radiation therapy plan adaptation for head and neck cancer: improved target coverage and organ at risk sparing","author":"Aly","year":"2018","journal-title":"Australas Phys Eng Sci Med"},{"key":"10.1016\/j.canrad.2019.06.015_bib0125","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.ando.2010.06.005","article-title":"Thyroid toxicity after radiotherapy of nasopharyngeal carcinoma","volume":"72","author":"Siala","year":"2011","journal-title":"Ann Endocrinol"},{"key":"10.1016\/j.canrad.2019.06.015_bib0130","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1016\/j.ijrobp.2009.03.011","article-title":"Hypothyroidism after radiotherapy for nasopharyngeal cancer patients","volume":"76","author":"Wu","year":"2010","journal-title":"Int J Radiat Oncol"},{"key":"10.1016\/j.canrad.2019.06.015_bib0135","doi-asserted-by":"crossref","first-page":"e0200310","DOI":"10.1371\/journal.pone.0200310","article-title":"Pattern of radiation-induced thyroid gland changes in nasopharyngeal carcinoma patients in 48\u00a0months after radiotherapy. Zhang Q, \u00e9diteur","volume":"13","author":"Lin","year":"2018","journal-title":"Plos One"},{"key":"10.1016\/j.canrad.2019.06.015_bib0140","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1016\/j.canrad.2010.03.007","article-title":"Dose de tol\u00e9rance \u00e0 l\u2019irradiation des tissus sains\u00a0: les glandes salivaires","volume":"14","author":"Ortholan","year":"2010","journal-title":"Cancer Radiother"},{"key":"10.1016\/j.canrad.2019.06.015_bib0145","doi-asserted-by":"crossref","first-page":"20160686","DOI":"10.1259\/bjr.20160686","article-title":"Nomogram for radiation-induced hypothyroidism prediction in nasopharyngeal carcinoma after treatment","volume":"90","author":"Luo","year":"2017","journal-title":"Br J Radiol"},{"key":"10.1016\/j.canrad.2019.06.015_bib0150","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/j.canrad.2010.03.005","article-title":"Dose de tol\u00e9rance des tissus sains\u00a0: la thyro\u00efde","volume":"14","author":"Berges","year":"2010","journal-title":"Cancer Radiother"},{"key":"10.1016\/j.canrad.2019.06.015_bib0155","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1016\/0360-3016(94)00427-M","article-title":"Chronic neuroendocrinological sequelae of radiation therapy","volume":"31","author":"Sklar","year":"1995","journal-title":"Int J Radiat Oncol"},{"key":"10.1016\/j.canrad.2019.06.015_bib0160","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1016\/j.ijrobp.2009.04.047","article-title":"Adaptive replanning strategies accounting for shrinkage in head and neck IMRT","volume":"75","author":"Wu","year":"2009","journal-title":"Int J Radiat Oncol"},{"key":"10.1016\/j.canrad.2019.06.015_bib0165","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/j.radonc.2012.03.013","article-title":"A prospective study on volumetric and dosimetric changes during intensity-modulated radiotherapy for nasopharyngeal carcinoma patients","volume":"104","author":"Cheng","year":"2012","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.canrad.2019.06.015_bib0170","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1016\/j.ijrobp.2009.08.036","article-title":"Clinical study of the necessity of replanning before the 25th fraction during the course of intensity-modulated radiotherapy for patients with nasopharyngeal carcinoma","volume":"77","author":"Wang","year":"2010","journal-title":"Int J Radiat Oncol"},{"key":"10.1016\/j.canrad.2019.06.015_bib0175","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1097\/01.coc.0000239093.95769.b3","article-title":"Effect of regression of enlarged neck lymph nodes on radiation doses received by parotid glands during intensity-modulated radiotherapy for head and neck cancer","volume":"29","author":"Kuo","year":"2006","journal-title":"Am J Clin Oncol"},{"key":"10.1016\/j.canrad.2019.06.015_bib0180","doi-asserted-by":"crossref","first-page":"e47","DOI":"10.1016\/j.ijrobp.2012.09.033","article-title":"Replanning during intensity modulated radiation therapy improved quality of life in patients with nasopharyngeal carcinoma","volume":"85","author":"Yang","year":"2013","journal-title":"Int J Radiat Oncol"},{"key":"10.1016\/j.canrad.2019.06.015_bib0185","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/j.radonc.2015.05.018","article-title":"Identifying patients who may benefit from adaptive radiotherapy: does the literature on anatomic and dosimetric changes in head and neck organs at risk during radiotherapy provide information to help?","volume":"115","author":"Brouwer","year":"2015","journal-title":"Radiother Oncol"}],"container-title":["Cancer\/Radioth\u00e9rapie"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S127832182030007X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S127832182030007X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T12:31:36Z","timestamp":1761136296000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S127832182030007X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,2]]},"references-count":37,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2020,2]]}},"alternative-id":["S127832182030007X"],"URL":"https:\/\/doi.org\/10.1016\/j.canrad.2019.06.015","relation":{},"ISSN":["1278-3218"],"issn-type":[{"type":"print","value":"1278-3218"}],"subject":[],"published":{"date-parts":[[2020,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Quel impact de la RCMI des carcinomes nasopharyng\u00e9s sur les structures glandulaires\u00a0?","name":"articletitle","label":"Article Title"},{"value":"Cancer\/Radioth\u00e9rapie","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.canrad.2019.06.015","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Soci\u00e9t\u00e9 fran\u00e7aise de radioth\u00e9rapie oncologique (SFRO). Published by Elsevier Masson SAS. All rights reserved.","name":"copyright","label":"Copyright"}]}}