{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T00:15:48Z","timestamp":1761178548193,"version":"build-2065373602"},"reference-count":44,"publisher":"Elsevier BV","issue":"6-7","license":[{"start":{"date-parts":[[2019,10,1]],"date-time":"2019-10-01T00:00:00Z","timestamp":1569888000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,10,1]],"date-time":"2019-10-01T00:00:00Z","timestamp":1569888000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,9,24]],"date-time":"2020-09-24T00:00:00Z","timestamp":1600905600000},"content-version":"am","delay-in-days":359,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.fr","em-consulte.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cancer\/Radioth\u00e9rapie"],"published-print":{"date-parts":[[2019,10]]},"DOI":"10.1016\/j.canrad.2019.07.130","type":"journal-article","created":{"date-parts":[[2019,9,3]],"date-time":"2019-09-03T09:32:59Z","timestamp":1567503179000},"page":"682-687","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Cancer of the oesophagus and lymph nodes management in the neoadjuvant or definitive radiochemotherapy setting"],"prefix":"10.1016","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2631-0029","authenticated-orcid":false,"given":"V.","family":"Bourbonn\u00e9","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"O.","family":"Pradier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"U.","family":"Schick","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Servagi-Vernat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.canrad.2019.07.130_bib0225","first-page":"7","article-title":"Cancer statistics, 2019; Cancer statistics, 2019","volume":"69","author":"Siegel","year":"2019","journal-title":"CA Cancer J Clin"},{"key":"10.1016\/j.canrad.2019.07.130_bib0230","doi-asserted-by":"crossref","first-page":"1160","DOI":"10.1200\/JCO.2005.04.7118","article-title":"Chemoradiation followed by surgery compared with chemoradiation alone in squamous cancer of the esophagus: FFCD 9102","volume":"25","author":"Bedenne","year":"2007","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.canrad.2019.07.130_bib0235","doi-asserted-by":"crossref","first-page":"2310","DOI":"10.1200\/JCO.2005.00.034","article-title":"Chemoradiation With and without surgery in patients with locally advanced squamous cell carcinoma of the esophagus","volume":"23","author":"Stahl","year":"2005","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.canrad.2019.07.130_bib0240","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1186\/s13014-016-0698-3","article-title":"Involved field radiotherapy (IFRT) versus elective nodal irradiation (ENI) for locally advanced non-small cell lung cancer: a meta-analysis of incidence of elective nodal failure (ENF)","volume":"11","author":"Li","year":"2016","journal-title":"Radiat Oncol"},{"key":"10.1016\/j.canrad.2019.07.130_bib0245","doi-asserted-by":"crossref","first-page":"6295","DOI":"10.2147\/CMAR.S182436","article-title":"Anatomy of lymphatic drainage of the esophagus and lymph node metastasis of thoracic esophageal cancer","volume":"10","author":"Wang","year":"2018","journal-title":"Cancer Manag Res"},{"key":"10.1016\/j.canrad.2019.07.130_bib0250","doi-asserted-by":"crossref","first-page":"S713","DOI":"10.21037\/jtd.2017.07.42","article-title":"The extent of lymphadenectomy in esophageal resection for cancer should be standardized","volume":"9","author":"Hagens","year":"2017","journal-title":"J Thorac Dis"},{"key":"10.1016\/j.canrad.2019.07.130_bib0255","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1245\/s10434-015-4819-2","article-title":"The prognostic relevance of subcarinal lymph node dissection in esophageal squamous cell carcinoma","volume":"23","author":"Niwa","year":"2016","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.canrad.2019.07.130_bib0260","doi-asserted-by":"crossref","first-page":"S731","DOI":"10.21037\/jtd.2017.03.171","article-title":"Three-field lymph node dissection in esophageal cancer surgery","volume":"9","author":"Matsuda","year":"2017","journal-title":"J Thorac Dis"},{"key":"10.1016\/j.canrad.2019.07.130_bib0265","doi-asserted-by":"crossref","first-page":"1593","DOI":"10.1056\/NEJM199206113262403","article-title":"Combined chemotherapy and radiotherapy compared with radiotherapy alone in patients with cancer of the esophagus","volume":"326","author":"Herskovic","year":"1992","journal-title":"N Engl J Med"},{"key":"10.1016\/j.canrad.2019.07.130_bib0270","doi-asserted-by":"crossref","first-page":"1167","DOI":"10.1200\/JCO.2002.20.5.1167","article-title":"INT 0123 (Radiation Therapy Oncology Group 94-05) Phase III trial of combined-modality therapy for esophageal cancer: high-dose versus standard-dose radiation therapy","volume":"20","author":"Minsky","year":"2002","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.canrad.2019.07.130_bib0275","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/S1470-2045(14)70028-2","article-title":"Definitive chemoradiotherapy with FOLFOX versus fluorouracil and cisplatin in patients with oesophageal cancer (PRODIGE5\/ACCORD17): final results of a randomised, phase 2\/3 trial","volume":"15","author":"Conroy","year":"2014","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.canrad.2019.07.130_bib0280","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1016\/S1470-2045(11)70142-5","article-title":"Survival after neoadjuvant chemotherapy or chemoradiotherapy for resectable oesophageal carcinoma: an updated meta-analysis","volume":"12","author":"Sjoquist","year":"2011","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.canrad.2019.07.130_bib0285","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1016\/j.ejca.2010.09.009","article-title":"Is concurrent radiation therapy required in patients receiving preoperative chemotherapy for adenocarcinoma of the oesophagus? A randomised phase II trial","volume":"47","author":"Burmeister","year":"2011","journal-title":"Eur J Cancer"},{"key":"10.1016\/j.canrad.2019.07.130_bib0290","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1200\/JCO.2008.17.0506","article-title":"Phase III comparison of preoperative chemotherapy compared with chemoradiotherapy in patients with locally advanced adenocarcinoma of the esophagogastric junction","volume":"27","author":"Stahl","year":"2009","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.canrad.2019.07.130_bib0295","doi-asserted-by":"crossref","first-page":"830","DOI":"10.6004\/jnccn.2011.0072","article-title":"Esophageal and esophagogastric junction cancers","volume":"9","author":"Ajani","year":"2011","journal-title":"J Natl Compr Canc Netw"},{"key":"10.1016\/j.canrad.2019.07.130_bib0300","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1186\/s13014-015-0482-9","article-title":"Involved-field radiotherapy (IFRT) versus elective nodal irradiation (ENI) in combination with concurrent chemotherapy for 239 esophageal cancers: a single institutional retrospective study","volume":"10","author":"Yamashita","year":"2015","journal-title":"Radiat Oncol"},{"key":"10.1016\/j.canrad.2019.07.130_bib0305","article-title":"Involved field irradiation (IFI) versus elective nodal irradiation (ENI) in combination with concurrent chemotherapy for esophageal thoracic squamous cell cancer: a prospective, randomized, multicenter, controlled study","author":"Lyu","year":"2017","journal-title":"Chinese J Radiat Oncol"},{"key":"10.1016\/j.canrad.2019.07.130_bib0310","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1093\/jrr\/rry055","article-title":"Comparison of elective nodal irradiation and involved-field irradiation in esophageal squamous cell carcinoma: a meta-analysis","volume":"59","author":"Cheng","year":"2018","journal-title":"J Radiat Res"},{"key":"10.1016\/j.canrad.2019.07.130_bib0315","doi-asserted-by":"crossref","first-page":"1126","DOI":"10.1016\/j.athoracsur.2012.05.106","article-title":"Salvage esophagectomy after failed definitive chemoradiation for esophageal adenocarcinoma","volume":"94","author":"Marks","year":"2012","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.canrad.2019.07.130_bib0320","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1159\/000351999","article-title":"Propensity-based matching between esophagogastric cancer patients who had surgery and who declined surgery after preoperative chemoradiation","volume":"85","author":"Taketa","year":"2013","journal-title":"Oncology"},{"key":"10.1016\/j.canrad.2019.07.130_bib0325","doi-asserted-by":"crossref","first-page":"3400","DOI":"10.1200\/JCO.2014.56.7156","article-title":"Importance of surveillance and success of salvage strategies after definitive chemoradiation in patients with esophageal cancer","volume":"32","author":"Sudo","year":"2014","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.canrad.2019.07.130_bib0330","doi-asserted-by":"crossref","first-page":"81","DOI":"10.21037\/atm.2018.01.31","article-title":"Surveillance versus esophagectomy in esophageal cancer patients with a clinical complete response after induction chemoradiation","volume":"6","author":"Semenkovich","year":"2018","journal-title":"Ann Transl Med"},{"key":"10.1016\/j.canrad.2019.07.130_bib0335","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1055\/s-0043-109021","article-title":"Indications, results, and clinical impact of endoscopic ultrasound (EUS)-guided sampling in gastroenterology: European Society of Gastrointestinal Endoscopy (ESGE) Clinical Guideline\u2013Updated January 2017","volume":"49","author":"Dumonceau","year":"2017","journal-title":"Endoscopy"},{"key":"10.1016\/j.canrad.2019.07.130_bib0340","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1038\/sj.bjc.6604200","article-title":"Staging investigations for oesophageal cancer: a meta-analysis","volume":"98","author":"van Vliet","year":"2008","journal-title":"Br J Cancer"},{"key":"10.1016\/j.canrad.2019.07.130_bib0345","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1586\/era.10.150","article-title":"Detection of lymph node metastases in esophageal cancer","volume":"11","author":"Sgourakis","year":"2011","journal-title":"Expert Rev Anticancer Ther"},{"key":"10.1016\/j.canrad.2019.07.130_bib0350","doi-asserted-by":"crossref","first-page":"1626","DOI":"10.1053\/j.gastro.2003.08.036","article-title":"Impact of lymph node staging on therapy of esophageal carcinoma","volume":"125","author":"Vazquez-Sequeiros","year":"2003","journal-title":"Gastroenterology"},{"key":"10.1016\/j.canrad.2019.07.130_bib0355","doi-asserted-by":"crossref","first-page":"868","DOI":"10.1007\/s11605-009-0812-z","article-title":"The early use of pet-ct alters the management of patients with esophageal cancer","volume":"13","author":"Williams","year":"2009","journal-title":"J Gastrointest Surg"},{"key":"10.1016\/j.canrad.2019.07.130_bib0360","first-page":"1495","article-title":"PET\/CT imaging in diagnosing lymph node metastasis of esophageal carcinoma and its comparison with pathological findings","author":"Wang","year":"2016","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"10.1016\/j.canrad.2019.07.130_bib0365","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1016\/j.canrad.2013.07.145","article-title":"Clinical target volume delineation for radiotherapy of the esophagus","volume":"17","author":"Lazarescu","year":"2013","journal-title":"Cancer Radiother"},{"key":"10.1016\/j.canrad.2019.07.130_bib0370","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/j.radonc.2005.10.017","article-title":"Feasibility of using intensity-modulated radiotherapy to improve lung sparing in treatment planning for distal esophageal cancer","volume":"77","author":"Chandra","year":"2005","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.canrad.2019.07.130_bib0375","doi-asserted-by":"crossref","first-page":"e7685","DOI":"10.1097\/MD.0000000000007685","article-title":"Comparison of IMRT versus 3D-CRT in the treatment of esophagus cancer: a systematic review and meta-analysis","volume":"96","author":"Xu","year":"2017","journal-title":"Medicine"},{"key":"10.1016\/j.canrad.2019.07.130_bib0380","first-page":"5266","article-title":"Volumetric-modulated arc therapy vs c-IMRT in esophageal cancer: a treatment planning comparison","volume":"18","author":"Yin","year":"2012","journal-title":"World J Gastroenterol"},{"key":"10.1016\/j.canrad.2019.07.130_bib0385","first-page":"43","article-title":"VMAT radiation-induced nausea and vomiting in adjuvant breast cancer radiotherapy: the incidental effect of low-dose bath exposure","volume":"7","author":"Lazzari","year":"2017","journal-title":"Clin Transl Radiat Oncol"},{"key":"10.1016\/j.canrad.2019.07.130_bib0390","doi-asserted-by":"crossref","first-page":"53","DOI":"10.21037\/cco.2016.07.04","article-title":"Proton beam therapy for the treatment of esophageal cancer","volume":"5","author":"Lin","year":"2016","journal-title":"Chin Clin Oncol"},{"key":"10.1016\/j.canrad.2019.07.130_bib0395","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1093\/jrr\/rrv001","article-title":"Comparison of adverse effects of proton and X-ray chemoradiotherapy for esophageal cancer using an adaptive dose\u2013volume histogram analysis","volume":"56","author":"Makishima","year":"2015","journal-title":"J Radiat Res (Tokyo)"},{"key":"10.1016\/j.canrad.2019.07.130_bib0400","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1016\/S0360-3016(98)00047-9","article-title":"Comparative treatment planning between proton and X-ray therapy in esophageal cancer","volume":"41","author":"Isacsson","year":"1998","journal-title":"Int J Radiat Oncol"},{"key":"10.1016\/j.canrad.2019.07.130_bib0405","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1016\/j.ijrobp.2008.05.014","article-title":"Four-dimensional computed tomography\u2013based treatment planning for intensity-modulated radiation therapy and proton therapy for distal esophageal cancer","volume":"72","author":"Zhang","year":"2008","journal-title":"Int J Radiat Oncol"},{"key":"10.1016\/j.canrad.2019.07.130_bib0410","doi-asserted-by":"crossref","first-page":"2356","DOI":"10.3390\/cancers6042356","article-title":"Analysis of intensity-modulated radiation therapy (IMRT), proton and 3d conformal radiotherapy (3D-CRT) for reducing perioperative cardiopulmonary complications in esophageal cancer patients","volume":"6","author":"Ling","year":"2014","journal-title":"Cancer"},{"key":"10.1016\/j.canrad.2019.07.130_bib0415","doi-asserted-by":"crossref","first-page":"4565","DOI":"10.1200\/jco.2007.25.18_suppl.4565","article-title":"A randomized clinical study of chemoradiotherapy versus radiotherapy in locoregional advanced unresectable esophageal cancer","volume":"25","author":"Zupanc","year":"2007","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.canrad.2019.07.130_bib0420","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1056\/NEJM199707173370304","article-title":"Chemoradiotherapy followed by surgery compared with surgery alone in squamous-cell cancer of the esophagus","volume":"337","author":"Bosset","year":"1997","journal-title":"N Engl J Med"},{"key":"10.1016\/j.canrad.2019.07.130_bib0425","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1200\/JCO.2001.19.2.305","article-title":"Randomized trial of preoperative chemoradiation versus surgery alone in patients with locoregional esophageal carcinoma","volume":"19","author":"Urba","year":"2001","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.canrad.2019.07.130_bib0430","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1093\/annonc\/mdh219","article-title":"A single institutional phase III trial of preoperative chemotherapy with hyperfractionation radiotherapy plus surgery versus surgery alone for resectable esophageal squamous cell carcinoma","volume":"15","author":"Lee","year":"2004","journal-title":"Ann Oncol"},{"key":"10.1016\/j.canrad.2019.07.130_bib0435","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1016\/S1470-2045(05)70288-6","article-title":"Surgery alone versus chemoradiotherapy followed by surgery for resectable cancer of the oesophagus: a randomised controlled phase III trial","volume":"6","author":"Burmeister","year":"2005","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.canrad.2019.07.130_bib0440","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.semradonc.2014.07.005","article-title":"Radiotherapy and immunogenic cell death","volume":"25","author":"Golden","year":"2015","journal-title":"Semin Radiat Oncol"}],"container-title":["Cancer\/Radioth\u00e9rapie"],"original-title":[],"language":"fr","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S127832181930304X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S127832181930304X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T12:31:51Z","timestamp":1761136311000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S127832181930304X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,10]]},"references-count":44,"journal-issue":{"issue":"6-7","published-print":{"date-parts":[[2019,10]]}},"alternative-id":["S127832181930304X"],"URL":"https:\/\/doi.org\/10.1016\/j.canrad.2019.07.130","relation":{},"ISSN":["1278-3218"],"issn-type":[{"type":"print","value":"1278-3218"}],"subject":[],"published":{"date-parts":[[2019,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cancer of the oesophagus and lymph nodes management in the neoadjuvant or definitive radiochemotherapy setting","name":"articletitle","label":"Article Title"},{"value":"Cancer\/Radioth\u00e9rapie","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.canrad.2019.07.130","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Soci\u00e9t\u00e9 fran\u00e7aise de radioth\u00e9rapie oncologique (SFRO). Published by Elsevier Masson SAS. All rights reserved.","name":"copyright","label":"Copyright"}]}}