{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T16:53:41Z","timestamp":1786985621828,"version":"build-2736575974"},"reference-count":45,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2020,4,1]],"date-time":"2020-04-01T00:00:00Z","timestamp":1585699200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,4,1]],"date-time":"2020-04-01T00:00:00Z","timestamp":1585699200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.fr","em-consulte.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cancer\/Radioth\u00e9rapie"],"published-print":{"date-parts":[[2020,4]]},"DOI":"10.1016\/j.canrad.2019.11.003","type":"journal-article","created":{"date-parts":[[2020,3,12]],"date-time":"2020-03-12T03:09:15Z","timestamp":1583982555000},"page":"120-127","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"title":["Radiation-induced lung toxicity predictors: Retrospective analysis of 90 patients treated with stereotactic body radiation therapy for stage I non-small-cell lung carcinoma"],"prefix":"10.1016","volume":"24","author":[{"given":"I.","family":"Menoux","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Antoni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Mazzara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Labani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Charloux","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Quoix","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.-E.","family":"Falcoz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Truntzer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"No\u00ebl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.canrad.2019.11.003_bib0230","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/j.canrad.2014.05.002","article-title":"[Stereotactic ablative irradiation for lung cancer]","volume":"18","author":"Antoni","year":"2014","journal-title":"Cancer Radiother"},{"key":"10.1016\/j.canrad.2019.11.003_bib0235","doi-asserted-by":"crossref","first-page":"1381","DOI":"10.1016\/j.ijrobp.2009.09.030","article-title":"Dose-volume analysis of radiation pneumonitis in non-small-cell lung cancer patients treated with concurrent cisplatinum and etoposide with or without consolidation docetaxel","volume":"78","author":"Barriger","year":"2010","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.canrad.2019.11.003_bib0240","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/j.radonc.2009.02.003","article-title":"Radiation pneumonitis in patients treated for malignant pulmonary lesions with hypofractionated radiation therapy","volume":"91","author":"Borst","year":"2009","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.canrad.2019.11.003_bib0245","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1016\/j.ijrobp.2012.03.041","article-title":"Clinical and dosimetric predictors of radiation pneumonitis in a large series of patients treated with stereotactic body radiation therapy to the lung","volume":"85","author":"Baker","year":"2013","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.canrad.2019.11.003_bib0250","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1016\/j.ijrobp.2015.07.2278","article-title":"Prospective Trial of Stereotactic Body Radiation Therapy for Both Operable and Inoperable T1N0M0 Non-Small Cell Lung Cancer: Japan Clinical Oncology Group Study JCOG0403","volume":"93","author":"Nagata","year":"2015","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.canrad.2019.11.003_bib0255","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1016\/j.radonc.2011.04.002","article-title":"Early pulmonary toxicity following lung stereotactic body radiation therapy delivered in consecutive daily fractions","volume":"99","author":"Stauder","year":"2011","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.canrad.2019.11.003_bib0260","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1080\/02841860802520821","article-title":"Dosimetric predictors of radiation-induced lung injury in stereotactic body radiation therapy","volume":"48","author":"Ricardi","year":"2009","journal-title":"Acta Oncol"},{"key":"10.1016\/j.canrad.2019.11.003_bib0265","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.radonc.2010.04.027","article-title":"Dose\u2013response relationship for radiation-induced pneumonitis after pulmonary stereotactic body radiotherapy","volume":"97","author":"Guckenberger","year":"2010","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.canrad.2019.11.003_bib0270","doi-asserted-by":"crossref","first-page":"e545","DOI":"10.1016\/j.ijrobp.2012.01.018","article-title":"Dose\u2013Volume Metrics Associated With Radiation Pneumonitis After Stereotactic Body Radiation Therapy for Lung Cancer","volume":"83","author":"Matsuo","year":"2012","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.canrad.2019.11.003_bib0275","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1016\/j.ijrobp.2009.06.001","article-title":"Early Graphical Appearance of Radiation Pneumonitis Correlates With the Severity of Radiation Pneumonitis After Stereotactic Body Radiotherapy (SBRT) in Patients With Lung Tumors","volume":"77","author":"Takeda","year":"2010","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.canrad.2019.11.003_bib0280","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1016\/j.radonc.2010.10.003","article-title":"Treatment of large stage I\u2013II lung tumors using stereotactic body radiotherapy (SBRT): Planning considerations and early toxicity","volume":"97","author":"Ong","year":"2010","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.canrad.2019.11.003_bib0285","first-page":"37","article-title":"Radiation-induced lung injury. Assessment, management, and prevention","volume":"22","author":"Ghafoori","year":"2008","journal-title":"Oncology (Williston Park, NY)"},{"key":"10.1016\/j.canrad.2019.11.003_bib0290","doi-asserted-by":"crossref","first-page":"1357","DOI":"10.1016\/j.ijrobp.2016.03.024","article-title":"Simple Factors Associated With Radiation-Induced Lung Toxicity After Stereotactic Body Radiation Therapy of the Thorax: A Pooled Analysis of 88 Studies","volume":"95","author":"Zhao","year":"2016","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.canrad.2019.11.003_bib0295","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.1016\/j.ijrobp.2013.12.050","article-title":"No Clinically Significant Changes in Pulmonary Function Following Stereotactic Body Radiation Therapy for Early- Stage Peripheral Non-Small Cell Lung Cancer: An Analysis of RTOG 0236","volume":"88","author":"Stanic","year":"2014","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.canrad.2019.11.003_bib0300","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1164\/ajrccm.165.3.2107134","article-title":"Comparative Study of KL-6, Surfactant Protein-A, Surfactant Protein-D, and Monocyte Chemoattractant Protein-1 as Serum Markers for Interstitial Lung Diseases","volume":"165","author":"Ohnishi","year":"2002","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.canrad.2019.11.003_bib0305","doi-asserted-by":"crossref","first-page":"8748","DOI":"10.1200\/JCO.2005.01.7145","article-title":"Early variations of circulating interleukin-6 and interleukin-10 levels during thoracic radiotherapy are predictive for radiation pneumonitis","volume":"23","author":"Arpin","year":"2005","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.canrad.2019.11.003_bib0310","doi-asserted-by":"crossref","first-page":"S36","DOI":"10.1016\/j.canrad.2016.07.032","article-title":"[Delineation of organs at risk and dose constraints]","volume":"20","author":"No\u00ebl","year":"2016","journal-title":"Cancer Radiother"},{"key":"10.1016\/j.canrad.2019.11.003_bib0315","article-title":"Dose calculation algorithm accuracy for small fields in non-homogeneous media: The lung SBRT case","author":"Fogliata","year":"2016","journal-title":"Phys Med"},{"key":"10.1016\/j.canrad.2019.11.003_bib0320","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.cllc.2015.08.007","article-title":"Renin-Angiotensin System Inhibitors Might Help to Reduce the Development of Symptomatic Radiation Pneumonitis After Stereotactic Body Radiotherapy for Lung Cancer","volume":"17","author":"Bracci","year":"2016","journal-title":"Clin Lung Cancer"},{"key":"10.1016\/j.canrad.2019.11.003_bib0325","doi-asserted-by":"crossref","first-page":"977","DOI":"10.2214\/ajr.169.4.9308447","article-title":"Thin-section CT obtained at 10-mm increments versus limited three-level thin-section CT for idiopathic pulmonary fibrosis: correlation with pathologic scoring","volume":"169","author":"Kazerooni","year":"1997","journal-title":"AJR Am J Roentgenol"},{"key":"10.1016\/j.canrad.2019.11.003_bib0330","doi-asserted-by":"crossref","first-page":"128","DOI":"10.4329\/wjr.v4.i4.128","article-title":"The 7th lung cancer TNM classification and staging system: Review of the changes and implications","volume":"4","author":"Mirsadraee","year":"2012","journal-title":"World J Radiol"},{"key":"10.1016\/j.canrad.2019.11.003_bib0335","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/j.ijrobp.2015.10.040","article-title":"Primary Study Endpoint Analysis for NRG Oncology\/RTOG 0813 Trial of Stereotactic Body Radiation Therapy (SBRT) for Centrally Located Non-Small Cell Lung Cancer (NSCLC)","volume":"94","author":"Bezjak","year":"2016","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.canrad.2019.11.003_bib0340","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1016\/S0360-3016(00)00750-1","article-title":"Evaluation of microscopic tumor extension in non-small-cell lung cancer for three-dimensional conformal radiotherapy planning","volume":"48","author":"Giraud","year":"2000","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.canrad.2019.11.003_bib0345","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1016\/j.ijrobp.2010.02.032","article-title":"Radiological and Clinical Pneumonitis After Stereotactic Lung Radiotherapy: A Matched Analysis of Three-Dimensional Conformal and Volumetric-modulated Arc Therapy Techniques","volume":"80","author":"Palma","year":"2011","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.canrad.2019.11.003_bib0350","doi-asserted-by":"crossref","first-page":"1383","DOI":"10.2214\/ajr.178.6.1781383","article-title":"Radiation injury of the lung after three-dimensional conformal radiation therapy","volume":"178","author":"Koenig","year":"2002","journal-title":"AJR Am J Roentgenol"},{"key":"10.1016\/j.canrad.2019.11.003_bib0355","first-page":"71","article-title":"The role of biologically effective dose (BED) in clinical oncology","volume":"13","author":"Jones","year":"2001","journal-title":"Clin Oncol (R Coll Radiol)"},{"key":"10.1016\/j.canrad.2019.11.003_bib0360","first-page":"1100","article-title":"A Generalized Concept of Equivalent Uniform Dose (EUD)","volume":"26","author":"Niemierko","year":"1999","journal-title":"Med Phys"},{"key":"10.1016\/j.canrad.2019.11.003_bib0365","doi-asserted-by":"crossref","first-page":"S13","DOI":"10.2307\/3583506","article-title":"Complication probability as assessed from dose-volume histograms","volume":"8","author":"Lyman","year":"1985","journal-title":"Radiat Res Suppl"},{"key":"10.1016\/j.canrad.2019.11.003_bib0370","doi-asserted-by":"crossref","first-page":"1623","DOI":"10.1016\/0360-3016(89)90972-3","article-title":"Calculation of complication probability factors for non-uniform normal tissue irradiation: The effective volume method gerald","volume":"16","author":"Kutcher","year":"1989","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.canrad.2019.11.003_bib0375","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1016\/j.ijrobp.2010.08.056","article-title":"A Dose\u2013Volume Analysis of Radiation Pneumonitis in Non\u2013Small Cell Lung Cancer Patients Treated With Stereotactic Body Radiation Therapy","volume":"82","author":"Barriger","year":"2012","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.canrad.2019.11.003_bib0380","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1183\/09031936.93.06081173","article-title":"Tobacco smoke exposure suppresses radiation-induced inflammation in the lung: a study of bronchoalveolar lavage and ultrastructural morphology in the rat","volume":"6","author":"Bjermer","year":"1993","journal-title":"Eur Respir J"},{"key":"10.1016\/j.canrad.2019.11.003_bib0385","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1378\/chest.82.5.526","article-title":"Reversible alterations in immunoregulatory T cells in smoking. Analysis by monoclonal antibodies and flow cytometry","volume":"82","author":"Miller","year":"1982","journal-title":"Chest"},{"key":"10.1016\/j.canrad.2019.11.003_bib0390","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1159\/000342371","article-title":"Impact of 3D conformal radiotherapy on lung function of patients with lung cancer: a prospective study","volume":"86","author":"Enache","year":"2013","journal-title":"Respiration"},{"key":"10.1016\/j.canrad.2019.11.003_bib0395","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1097\/JTO.0000000000000187","article-title":"Combined analysis of V20, VS5, pulmonary fibrosis score on baseline computed tomography, and patient age improves prediction of severe radiation pneumonitis after concurrent chemoradiotherapy for locally advanced non-small-cell lung cancer","volume":"9","author":"Tsujino","year":"2014","journal-title":"J Thorac Oncol"},{"key":"10.1016\/j.canrad.2019.11.003_bib0400","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/j.ijrobp.2017.01.186","article-title":"Treatment-Related Toxicity in Patients with Early Stage Non-Small Cell Lung Cancer and Co-Existing Interstitial Lung Disease: A Systematic Review","volume":"98","author":"Chen","year":"2017","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.canrad.2019.11.003_bib0405","article-title":"Dosimetric factors and Lyman normal-tissue complication modelling analysis for predicting radiation-induced lung injury in postoperative breast cancer radiotherapy: a prospective study","volume":"8","author":"Zhou","year":"2017","journal-title":"Oncotarget"},{"key":"10.1016\/j.canrad.2019.11.003_bib0410","doi-asserted-by":"crossref","DOI":"10.3389\/fonc.2019.00130","article-title":"PACE: A Probabilistic Atlas for Normal Tissue Complication Estimation in Radiation Oncology","volume":"9","author":"Palma","year":"2019","journal-title":"Front Oncol"},{"key":"10.1016\/j.canrad.2019.11.003_bib0415","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1172\/JCI40283","article-title":"Inhibition of vasculogenesis, but not angiogenesis, prevents the recurrence of glioblastoma after irradiation in mice","volume":"120","author":"Kioi","year":"2010","journal-title":"J Clin Invest"},{"key":"10.1016\/j.canrad.2019.11.003_bib0420","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.ccr.2005.07.014","article-title":"Engaging the vascular component of the tumor response","volume":"8","author":"Fuks","year":"2005","journal-title":"Cancer Cell"},{"key":"10.1016\/j.canrad.2019.11.003_bib0425","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/S0092-8674(00)80091-4","article-title":"Acid sphingomyelinase-deficient human lymphoblasts and mice are defective in radiation-induced apoptosis","volume":"86","author":"Santana","year":"1996","journal-title":"Cell"},{"key":"10.1016\/j.canrad.2019.11.003_bib0430","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1016\/j.ijrobp.2009.12.069","article-title":"Red shell: defining a high-risk zone of normal tissue damage in stereotactic body radiation therapy","volume":"77","author":"Yang","year":"2010","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.canrad.2019.11.003_bib0435","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1016\/j.ijrobp.2015.08.024","article-title":"Combined Ventilation and Perfusion Imaging Correlates With the Dosimetric Parameters of Radiation Pneumonitis in Radiation Therapy Planning for Lung Cancer","volume":"93","author":"Kimura","year":"2015","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.canrad.2019.11.003_bib0440","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.radonc.2015.08.005","article-title":"Inclusion of functional information from perfusion SPECT improves predictive value of dose-volume parameters in lung toxicity outcome after radiotherapy for non-small cell lung cancer: A Prospective Study","volume":"117","author":"Farr","year":"2015","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.canrad.2019.11.003_bib0445","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/j.radonc.2018.12.015","article-title":"Modeling radiation pneumonitis of pulmonary stereotactic body radiotherapy: The impact of a local dose\u2013effect relationship for lung perfusion loss","volume":"132","author":"Selvaraj","year":"2019","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.canrad.2019.11.003_bib0450","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1269\/jrr.11035","article-title":"Angiotensin converting enzyme inhibitors mitigate collagen synthesis induced by a single dose of radiation to the whole thorax","volume":"53","author":"Kma","year":"2012","journal-title":"J Radiat Res"}],"container-title":["Cancer\/Radioth\u00e9rapie"],"original-title":[],"language":"fr","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1278321820300597?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1278321820300597?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T12:31:48Z","timestamp":1761136308000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1278321820300597"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,4]]},"references-count":45,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2020,4]]}},"alternative-id":["S1278321820300597"],"URL":"https:\/\/doi.org\/10.1016\/j.canrad.2019.11.003","relation":{},"ISSN":["1278-3218"],"issn-type":[{"value":"1278-3218","type":"print"}],"subject":[],"published":{"date-parts":[[2020,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Radiation-induced lung toxicity predictors: Retrospective analysis of 90 patients treated with stereotactic body radiation therapy for stage I non-small-cell lung carcinoma","name":"articletitle","label":"Article Title"},{"value":"Cancer\/Radioth\u00e9rapie","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.canrad.2019.11.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Soci\u00e9t\u00e9 fran\u00e7aise de radioth\u00e9rapie oncologique (SFRO). Published by Elsevier Masson SAS. All rights reserved.","name":"copyright","label":"Copyright"}]}}