{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T12:15:23Z","timestamp":1767183323789,"version":"build-2065373602"},"reference-count":69,"publisher":"Elsevier BV","issue":"6-7","license":[{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,9,23]],"date-time":"2022-09-23T00:00:00Z","timestamp":1663891200000},"content-version":"am","delay-in-days":357,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.fr","em-consulte.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cancer\/Radioth\u00e9rapie"],"published-print":{"date-parts":[[2021,10]]},"DOI":"10.1016\/j.canrad.2021.07.007","type":"journal-article","created":{"date-parts":[[2021,8,11]],"date-time":"2021-08-11T08:26:21Z","timestamp":1628670381000},"page":"723-728","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["Unrecognized digestive toxicities of radiation therapy"],"prefix":"10.1016","volume":"25","author":[{"given":"G.","family":"Camprodon","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Huguet","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.canrad.2021.07.007_bib0350","unstructured":"Coia LR, Tepper JE, ChaseCancerCenter F, RadiationOncology D, RadiationOncology D. THERAPY ON THE TRACT.: 24."},{"key":"10.1016\/j.canrad.2021.07.007_bib0355","doi-asserted-by":"crossref","first-page":"1705","DOI":"10.1097\/01.RVI.0000179813.93992.9E","article-title":"Fluoroscopically Guided Balloon Dilation for Patients with Esophageal Stricture after Radiation Treatment","volume":"16","author":"Choi","year":"2005","journal-title":"J Vasc Interv Radiol"},{"key":"10.1016\/j.canrad.2021.07.007_bib0360","doi-asserted-by":"crossref","unstructured":"O\u2019Rourke IC, Bull C. Swallowing performance after radiation therapy for carcinoma of the esophagus. 61(10):5.","DOI":"10.1002\/1097-0142(19880515)61:10<2022::AID-CNCR2820611016>3.0.CO;2-0"},{"key":"10.1016\/j.canrad.2021.07.007_bib0365","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1177\/0284185117713351","article-title":"Radiation-induced esophageal strictures treated with fluoroscopic balloon dilation: clinical outcomes and factors influencing recurrence in 62 patients","volume":"59","author":"Park","year":"2018","journal-title":"Acta Radiol"},{"key":"10.1016\/j.canrad.2021.07.007_bib0370","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/S0016-5107(94)70062-1","article-title":"Dilation of esophageal strictures induced by radiation therapy for cancer of the esophagus","volume":"40","author":"Swaroop","year":"1994","journal-title":"Gastrointest Endosc"},{"issue":"1","key":"10.1016\/j.canrad.2021.07.007_bib0375","doi-asserted-by":"crossref","first-page":"940","DOI":"10.1093\/jrr\/rru031","article-title":"Esophageal perforation during or after conformal radiotherapy for esophageal carcinoma","volume":"55","author":"Chen","year":"2014","journal-title":"J Radiat Res (Tokyo)"},{"key":"10.1016\/j.canrad.2021.07.007_bib0380","doi-asserted-by":"crossref","first-page":"1051","DOI":"10.1007\/s00268-013-1951-7","article-title":"Current Treatment and Outcome of Esophageal Perforations in Adults: Systematic Review and Meta-Analysis of 75 Studies","volume":"37","author":"Biancari","year":"2013","journal-title":"World J Surg"},{"key":"10.1016\/j.canrad.2021.07.007_bib0385","doi-asserted-by":"crossref","first-page":"3693","DOI":"10.7150\/jca.39033","article-title":"Risk Factors Associated with Esophageal Fistula after Radiotherapy for Esophageal Squamous Cell Carcinoma","volume":"11","author":"Hu","year":"2020","journal-title":"J Cancer"},{"key":"10.1016\/j.canrad.2021.07.007_bib0390","doi-asserted-by":"crossref","first-page":"2311","DOI":"10.2147\/OTT.S161803","article-title":"Risk factors for esophageal fistula in patients with locally advanced esophageal carcinoma receiving chemoradiotherapy","volume":"11","author":"Zhang","year":"2018","journal-title":"OncoTargets Ther"},{"key":"10.1016\/j.canrad.2021.07.007_bib0395","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1002\/jso.2930480316","article-title":"Chemo-irradiation induced aortoesophageal fistula","volume":"48","author":"Gabrail","year":"1991","journal-title":"J Surg Oncol"},{"key":"10.1016\/j.canrad.2021.07.007_bib0400","first-page":"422","article-title":"Fatal hemorrhage complicating carcinoma of the esophagus. Report of four cases","volume":"65","author":"Alrenga","year":"1976","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.canrad.2021.07.007_bib0405","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/0002-9343(91)90129-L","article-title":"Aortoesophageal Fistula: A comprehensive review of the literature","volume":"91","author":"Hollander","year":"1991","journal-title":"Am J Med"},{"key":"10.1016\/j.canrad.2021.07.007_bib0410","doi-asserted-by":"crossref","first-page":"940","DOI":"10.1093\/jrr\/rru031","article-title":"Esophageal perforation during or after conformal radiotherapy for esophageal carcinoma","volume":"55","author":"Chen","year":"2014","journal-title":"J Radiat Res (Tokyo)"},{"key":"10.1016\/j.canrad.2021.07.007_bib0415","unstructured":"Ryom P, Ravn JB, Penninga L, Schmidt S, Iversen MG, Skov-Olsen P, et al. Aetiology, treatment and mortality after oesophageal perforation in Denmark.:4."},{"key":"10.1016\/j.canrad.2021.07.007_bib0420","doi-asserted-by":"crossref","first-page":"e156","DOI":"10.1002\/bjs.9338","article-title":"Spectrum of oesophageal perforations and their influence on management","volume":"101","author":"Wahed","year":"2013","journal-title":"Br J Surg"},{"key":"10.1016\/j.canrad.2021.07.007_bib0425","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1097\/00000658-199704000-00011","article-title":"Nonoperative Management of Esophageal Perforations: Is It Justified?","volume":"225","author":"Altorjay","year":"1997","journal-title":"Ann Surg"},{"key":"10.1016\/j.canrad.2021.07.007_bib0430","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/j.ijrobp.2004.06.014","article-title":"Dosimetric and clinical predictors for radiation-induced esophageal injury","volume":"61","author":"Ahn","year":"2005","journal-title":"Int J Radiat Oncol"},{"key":"10.1016\/j.canrad.2021.07.007_bib0435","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/j.canrad.2010.02.008","article-title":"Dose de tol\u00e9rance \u00e0 l\u2019irradiation des tissus sains: l\u2019\u0153sophage","volume":"14","author":"Bera","year":"2010","journal-title":"Cancer\/Radioth\u00e9rapie"},{"key":"10.1016\/j.canrad.2021.07.007_bib0440","unstructured":"Bismar MM, Sinicrope FA. Radiation enteritis.:5."},{"key":"10.1016\/j.canrad.2021.07.007_bib0445","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1007\/s11894-013-0355-z","article-title":"Management of Radiation-Induced Rectal Bleeding","volume":"15","author":"Laterza","year":"2013","journal-title":"Curr Gastroenterol Rep"},{"key":"10.1016\/j.canrad.2021.07.007_bib0450","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1136\/gutjnl-2011-300563","article-title":"Practice guidance on the management of acute and chronic gastrointestinal problems arising as a result of treatment for cancer","volume":"61","author":"Andreyev","year":"2012","journal-title":"Gut"},{"key":"10.1016\/j.canrad.2021.07.007_bib0455","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1007\/s00066-010-2211-5","article-title":"Healing of Late Endoscopic Changes in the Rectum between 12 and 65 Months after External Beam Radiotherapy","volume":"187","author":"Goldner","year":"2011","journal-title":"Strahlenther Onkol"},{"key":"10.1016\/j.canrad.2021.07.007_bib0460","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/S0360-3016(03)01395-6","article-title":"Rectal bleeding and its management after irradiation for uterine cervical cancer","volume":"58","author":"Chun","year":"2004","journal-title":"Int J Radiat Oncol"},{"key":"10.1016\/j.canrad.2021.07.007_bib0465","unstructured":"\u00c8av\u00e8i J, Tur\u00e8i J, Martinac P, Jelin\u00e8i \u017d, \u017dupan\u00e8i B, Unu\u0161i J. Metronidazole in the Treatment of Chronic Radiation Proctitis: Clinical Trial. Croat Med J.:5."},{"key":"10.1016\/j.canrad.2021.07.007_bib0470","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1007\/BF01300096","article-title":"Radiation-induced proctosigmoiditis","volume":"36","author":"Kochhar","year":"1991","journal-title":"Dig Dis Sci"},{"key":"10.1016\/j.canrad.2021.07.007_bib0475","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/j.ijrobp.2007.12.048","article-title":"Hyperbaric Oxygen Treatment of Chronic Refractory Radiation Proctitis: A Randomized and Controlled Double-Blind Crossover Trial With Long-Term Follow-Up","volume":"72","author":"Clarke","year":"2008","journal-title":"Int J Radiat Oncol"},{"key":"10.1016\/j.canrad.2021.07.007_bib0480","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1089\/ars.2013.5652","article-title":"Stem Cell Therapies for the Treatment of Radiation-Induced Normal Tissue Side Effects","volume":"21","author":"Benderitter","year":"2014","journal-title":"Antioxid Redox Signal"},{"key":"10.1016\/j.canrad.2021.07.007_bib0485","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1007\/s11373-008-9256-9","article-title":"Effects of transplanted bone marrow mesenchymal stem cells on the irradiated intestine of mice","volume":"15","author":"Zhang","year":"2008","journal-title":"J Biomed Sci"},{"key":"10.1016\/j.canrad.2021.07.007_bib0490","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/j.canrad.2007.09.004","article-title":"L\u2019accident d\u2019\u00c9pinal: pass\u00e9, pr\u00e9sent, avenir","volume":"11","author":"Peiffert","year":"2007","journal-title":"Cancer\/Radioth\u00e9rapie"},{"key":"10.1016\/j.canrad.2021.07.007_bib0495","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1007\/s12016-012-8347-6","article-title":"Use of Mesenchymal Stem Cells (MSC) in Chronic Inflammatory Fistulizing and Fibrotic Diseases: a Comprehensive Review","volume":"45","author":"Voswinkel","year":"2013","journal-title":"Clin Rev Allergy Immunol"},{"key":"10.1016\/j.canrad.2021.07.007_bib0500","doi-asserted-by":"crossref","first-page":"1427","DOI":"10.1080\/0284186X.2018.1503713","article-title":"Late gastrointestinal toxicity after radiotherapy for anal cancer: a systematic literature review","volume":"57","author":"Pan","year":"2018","journal-title":"Acta Oncol"},{"key":"10.1016\/j.canrad.2021.07.007_bib0505","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1016\/j.ijrobp.2011.07.007","article-title":"Twenty-Five-Year Experience With Radical Chemoradiation for Anal Cancer","volume":"83","author":"Tomaszewski","year":"2012","journal-title":"Int J Radiat Oncol"},{"key":"10.1016\/j.canrad.2021.07.007_bib0510","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.1245\/s10434-007-9794-9","article-title":"Patterns of Failure and Outcome in Patients with Carcinoma of the Anal Margin","volume":"15","author":"Khanfir","year":"2008","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.canrad.2021.07.007_bib0515","doi-asserted-by":"crossref","first-page":"1941","DOI":"10.1200\/JCO.2011.35.4837","article-title":"Induction Chemotherapy and Dose Intensification of the Radiation Boost in Locally Advanced Anal Canal Carcinoma: Final Analysis of the Randomized UNICANCER ACCORD 03 Trial","volume":"30","author":"Peiffert","year":"2012","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.canrad.2021.07.007_bib0520","first-page":"8","volume":"52","author":"Baglan","year":"2002","journal-title":"The dose\u2013volume relationship of acute small bowel toxicity from concurrent 5-fu\u2013based chemotherapy and radiation therapy for rectal cancer"},{"key":"10.1016\/j.canrad.2021.07.007_bib0525","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/j.ijrobp.2007.06.066","article-title":"The Dose\u2013Volume Relationship of Small Bowel Irradiation and Acute Grade 3 Diarrhea During Chemoradiotherapy for Rectal Cancer","volume":"70","author":"Robertson","year":"2008","journal-title":"Int J Radiat Oncol"},{"key":"10.1016\/j.canrad.2021.07.007_bib0530","doi-asserted-by":"crossref","first-page":"732","DOI":"10.1016\/j.ijrobp.2007.03.060","article-title":"The Different Volume Effects of Small-Bowel Toxicity During Pelvic Irradiation Between Gynecologic Patients With and Without Abdominal Surgery: A Prospective Study With Computed Tomography-Based Dosimetry","volume":"69","author":"Huang","year":"2007","journal-title":"Int J Radiat Oncol"},{"key":"10.1016\/j.canrad.2021.07.007_bib0535","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.ijrobp.2008.10.086","article-title":"Dose\u2013Volume Relationships for Acute Bowel Toxicity in Patients Treated With Pelvic Nodal Irradiation for Prostate Cancer","volume":"75","author":"Fiorino","year":"2009","journal-title":"Int J Radiat Oncol"},{"key":"10.1016\/j.canrad.2021.07.007_bib0540","doi-asserted-by":"crossref","first-page":"e359","DOI":"10.1038\/emm.2017.85","article-title":"Radiation-induced liver disease: current understanding and future perspectives","volume":"49","author":"Kim","year":"2017","journal-title":"Exp Mol Med"},{"key":"10.1016\/j.canrad.2021.07.007_bib0545","unstructured":"Khozouz RF, Huq SZ, Perry MC. Radiation-Induced Liver Disease.:2."},{"key":"10.1016\/j.canrad.2021.07.007_bib0550","doi-asserted-by":"crossref","first-page":"1237","DOI":"10.1016\/0360-3016(94)00418-K","article-title":"Hepatic toxicity resulting from cancer treatment","volume":"31","author":"Lawrence","year":"1995","journal-title":"Int J Radiat Oncol."},{"key":"10.1016\/j.canrad.2021.07.007_bib0555","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1016\/S0360-3016(01)01522-X","article-title":"Selective radioprotection of hepatocytes by systemic and portal vein infusions of amifostine in a rat liver tumor model","volume":"50","author":"Symon","year":"2001","journal-title":"Int J Radiat Oncol."},{"key":"10.1016\/j.canrad.2021.07.007_bib0560","doi-asserted-by":"crossref","first-page":"1441","DOI":"10.1016\/j.ijrobp.2011.10.020","article-title":"A Phase I Clinical and Pharmacology Study Using Amifostine as a Radioprotector in Dose-escalated Whole Liver Radiation Therapy","volume":"83","author":"Feng","year":"2012","journal-title":"Int J Radiat Oncol"},{"key":"10.1016\/j.canrad.2021.07.007_bib0565","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1093\/jrr\/rrv026","article-title":"Mesenchymal stem cell\u2013conditioned medium prevents radiation-induced liver injury by inhibiting inflammation and protecting sinusoidal endothelial cells","volume":"56","author":"Chen","year":"2015","journal-title":"J Radiat Res (Tokyo)"},{"key":"10.1016\/j.canrad.2021.07.007_bib0570","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.gcb.2009.06.013","article-title":"Radiation-induced cholangitis with hepatocellular carcinoma","volume":"34","author":"Gorea","year":"2010","journal-title":"Gastroent\u00e9rologie Clin Biol"},{"key":"10.1016\/j.canrad.2021.07.007_bib0575","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1016\/S0025-6196(12)62000-X","article-title":"Hepatic Duct Stricture After Radical Radiation Therapy for Biliary Cancer: Recurrence or Fibrosis?","volume":"61","author":"Martenson","year":"1986","journal-title":"Mayo Clin Proc"},{"key":"10.1016\/j.canrad.2021.07.007_bib0580","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1016\/S1590-8658(01)80111-0","article-title":"Magnetic resonance cholangiographic assessment of a delayed radiation-induced bile duct stricture","volume":"33","author":"Di Fiore","year":"2001","journal-title":"Dig Liver Dis"},{"key":"10.1016\/j.canrad.2021.07.007_bib0585","first-page":"855","volume":"1219","author":"Helmer","year":"2001","journal-title":"St\u00e9nose radique de la papille et du chol\u00e9doque: succ\u00e8s de la dilatation au ballonnet"},{"key":"10.1016\/j.canrad.2021.07.007_bib0590","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.ijrobp.2005.11.034","article-title":"Prediction of radiation-induced liver disease by Lyman normal-tissue complication probability model in three-dimensional conformal radiation therapy for primary liver carcinoma","volume":"65","author":"Xu","year":"2006","journal-title":"Int J Radiat Oncol"},{"key":"10.1016\/j.canrad.2021.07.007_bib0595","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1016\/j.ijrobp.2005.12.031","article-title":"Radiation-induced liver disease in three-dimensional conformal radiation therapy for primary liver carcinoma: The risk factors and hepatic radiation tolerance","volume":"65","author":"Liang","year":"2006","journal-title":"Int J Radiat Oncol"},{"key":"10.1016\/j.canrad.2021.07.007_bib0600","doi-asserted-by":"crossref","first-page":"1502","DOI":"10.1016\/j.ijrobp.2004.05.048","article-title":"Biologic susceptibility of hepatocellular carcinoma patients treated with radiotherapy to radiation-induced liver disease","volume":"60","author":"Cheng","year":"2004","journal-title":"Int J Radiat Oncol"},{"key":"10.1016\/j.canrad.2021.07.007_bib0605","doi-asserted-by":"crossref","first-page":"810","DOI":"10.1016\/S0360-3016(02)02846-8","article-title":"Analysis of radiation-induced liver disease using the Lyman NTCP model","volume":"53","author":"Dawson","year":"2002","journal-title":"Int J Radiat Oncol"},{"key":"10.1016\/j.canrad.2021.07.007_bib0610","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/S0360-3016(02)03929-9","article-title":"Clinical results and prognostic factors in radiotherapy for unresectable hepatocellular carcinoma: a retrospective study of 158 patients","volume":"55","author":"Seong","year":"2003","journal-title":"Int J Radiat Oncol"},{"key":"10.1016\/j.canrad.2021.07.007_bib0615","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/0360-3016(91)90171-Y","article-title":"Tolerance of normal tissue to therapeutic irradiation","volume":"21","author":"Emami","year":"1991","journal-title":"Int J Radiat Oncol"},{"key":"10.1016\/j.canrad.2021.07.007_bib0620","doi-asserted-by":"crossref","first-page":"168","DOI":"10.4103\/0973-1482.19597","article-title":"Analytical approach to estimate normal tissue complication probability using best fit of normal tissue tolerance doses into the NTCP equation of the linear quadratic model","volume":"1","author":"Kehwar","year":"2005","journal-title":"J Cancer Res Ther"},{"key":"10.1016\/j.canrad.2021.07.007_bib0625","doi-asserted-by":"crossref","first-page":"S94","DOI":"10.1016\/j.ijrobp.2009.06.092","article-title":"Radiation-Associated Liver Injury","volume":"76","author":"Pan","year":"2010","journal-title":"Int J Radiat Oncol"},{"key":"10.1016\/j.canrad.2021.07.007_bib0630","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1186\/s13014-015-0489-2","article-title":"Late gastrointestinal tissue effects after hypofractionated radiation therapy of the pancreas","volume":"10","author":"Elhammali","year":"2015","journal-title":"Radiat Oncol"},{"key":"10.1016\/j.canrad.2021.07.007_bib0635","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1007\/s10388-019-00680-1","article-title":"Gastric mucosal injury and hemorrhage after definitive chemoradiotherapy for locally advanced esophageal cancer","volume":"16","author":"Monma","year":"2019","journal-title":"Esophagus"},{"key":"10.1016\/j.canrad.2021.07.007_bib0640","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/j.ijrobp.2011.12.026","article-title":"Analysis of Dosimetric Parameters Associated With Acute Gastrointestinal Toxicity and Upper Gastrointestinal Bleeding in Locally Advanced Pancreatic Cancer Patients Treated With Gemcitabine-Based Concurrent Chemoradiotherapy","volume":"84","author":"Nakamura","year":"2012","journal-title":"Int J Radiat Oncol"},{"key":"10.1016\/j.canrad.2021.07.007_bib0645","doi-asserted-by":"crossref","first-page":"1343","DOI":"10.1016\/j.ijrobp.2010.07.1986","article-title":"Gastroduodenal Complications After Concurrent Chemoradiation Therapy in Patients With Hepatocellular Carcinoma: Endoscopic Findings and Risk Factors","volume":"81","author":"Chon","year":"2011","journal-title":"Int J Radiat Oncol"},{"key":"10.1016\/j.canrad.2021.07.007_bib0650","doi-asserted-by":"crossref","first-page":"1120","DOI":"10.1016\/j.ijrobp.2011.09.022","article-title":"Dose\u2013Volume Analysis of Predictors for Gastrointestinal Toxicity After Concurrent Full-Dose Gemcitabine and Radiotherapy for Locally Advanced Pancreatic Adenocarcinoma","volume":"83","author":"Huang","year":"2012","journal-title":"Int J Radiat Oncol"},{"key":"10.1016\/j.canrad.2021.07.007_bib0655","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1016\/j.canrad.2017.07.036","article-title":"Contraintes de doses aux organes \u00e0 risque en radioth\u00e9rapie conformationnelle et st\u00e9r\u00e9otaxique: intestin gr\u00eale et duod\u00e9num","volume":"21","author":"Goupy","year":"2017","journal-title":"Cancer\/Radioth\u00e9rapie"},{"key":"10.1016\/j.canrad.2021.07.007_bib0660","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/j.semradonc.2015.12.002","article-title":"Dose-Volume Histogram Analysis of Stereotactic Body Radiotherapy Treatment of Pancreatic Cancer: A Focus on Duodenal Dose Constraints","volume":"26","author":"Goldsmith","year":"2016","journal-title":"Semin Radiat Oncol"},{"key":"10.1016\/j.canrad.2021.07.007_bib0665","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1093\/jnci\/djz152","article-title":"Radiation Dose and Volume to the Pancreas and Subsequent Risk of Diabetes Mellitus: A Report from the Childhood Cancer Survivor Study","volume":"112","author":"Friedman","year":"2020","journal-title":"JNCI J Natl Cancer Inst"},{"key":"10.1016\/j.canrad.2021.07.007_bib0670","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1016\/0016-5085(93)90911-U","article-title":"Abdominal radiotherapy is a cause for chronic pancreatitis","volume":"105","author":"L\u00e9vy","year":"1993","journal-title":"Gastroenterology"},{"key":"10.1016\/j.canrad.2021.07.007_bib0675","series-title":"ALERT Adverse Late Effects of Cancer Treatment [Internet]","first-page":"427","article-title":"Adverse Late Effects of Radiation Treatment in the Pancreas","author":"Russo","year":"2014"},{"key":"10.1016\/j.canrad.2021.07.007_bib0680","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1016\/j.radonc.2015.11.033","article-title":"Radiation-induced injury of the exocrine pancreas after chemoradiotherapy for gastric cancer","volume":"118","author":"Wydmanski","year":"2016","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.canrad.2021.07.007_bib0685","doi-asserted-by":"crossref","first-page":"1002","DOI":"10.1016\/S1470-2045(12)70323-6","article-title":"Radiation dose to the pancreas and risk of diabetes mellitus in childhood cancer survivors: a retrospective cohort study","volume":"13","author":"de\u00a0Vathaire","year":"2012","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.canrad.2021.07.007_bib0690","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/S0360-3016(99)00163-7","article-title":"Clinical and dosimetric predictors of radiation-induced esophageal toxicity","volume":"45","author":"Maguire","year":"1999","journal-title":"Int J Radiat Oncol"}],"container-title":["Cancer\/Radioth\u00e9rapie"],"original-title":[],"language":"fr","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1278321821001608?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1278321821001608?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T12:33:51Z","timestamp":1761136431000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1278321821001608"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,10]]},"references-count":69,"journal-issue":{"issue":"6-7","published-print":{"date-parts":[[2021,10]]}},"alternative-id":["S1278321821001608"],"URL":"https:\/\/doi.org\/10.1016\/j.canrad.2021.07.007","relation":{},"ISSN":["1278-3218"],"issn-type":[{"type":"print","value":"1278-3218"}],"subject":[],"published":{"date-parts":[[2021,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Unrecognized digestive toxicities of radiation therapy","name":"articletitle","label":"Article Title"},{"value":"Cancer\/Radioth\u00e9rapie","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.canrad.2021.07.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Soci\u00e9t\u00e9 fran\u00e7aise de radioth\u00e9rapie oncologique (SFRO). Published by Elsevier Masson SAS. All rights reserved.","name":"copyright","label":"Copyright"}]}}