{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T11:19:24Z","timestamp":1789643964567,"version":"4.0.0"},"reference-count":20,"publisher":"Elsevier BV","issue":"6-7","license":[{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100011676","name":"Elekta","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100011676","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100020986","name":"Fondation de l&apos;H\u00f4pital g\u00e9n\u00e9ral juif","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100020986","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.fr","em-consulte.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cancer\/Radioth\u00e9rapie"],"published-print":{"date-parts":[[2022,10]]},"DOI":"10.1016\/j.canrad.2022.07.001","type":"journal-article","created":{"date-parts":[[2022,8,26]],"date-time":"2022-08-26T00:28:44Z","timestamp":1661473724000},"page":"879-883","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"title":["Clinical applications of high dose rate endorectal brachytherapy for patients with rectal cancer"],"prefix":"10.1016","volume":"26","author":[{"given":"T.","family":"Vuong","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Garant","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V.","family":"Vendrely","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.-G.","family":"Martin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Devic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.canrad.2022.07.001_bib0105","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1056\/NEJMoa010580","article-title":"Preoperative radiotherapy combined with total mesorectal excision for resectable rectal cancer","volume":"345","author":"Kapiteijn","year":"2001","journal-title":"N Engl J Med"},{"key":"10.1016\/j.canrad.2022.07.001_bib0110","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1097\/01.sla.0000257358.56863.ce","article-title":"The TME trial after a median follow-up of 6 years: increased local control but no survival benefit in irradiated patients with resectable rectal carcinoma","volume":"246","author":"Peeters","year":"2007","journal-title":"Ann Surg"},{"key":"10.1016\/j.canrad.2022.07.001_bib0115","doi-asserted-by":"crossref","first-page":"6199","DOI":"10.1200\/JCO.2005.14.779","article-title":"Late side effects of short course preoperative radiotherapy combined with total mesorectal excision for rectal cancer: Increase dowel dysfunction in irradiated patients. A Dutch colorectal cancer group","volume":"23","author":"Peeters","year":"2005","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.canrad.2022.07.001_bib0120","doi-asserted-by":"crossref","first-page":"1847","DOI":"10.1200\/JCO.2005.05.256","article-title":"Impact of short-term preoperative radiotherapy on health-related quality of life and sexual functioning in primary rectal cancer: report of a multicenter randomized trial","volume":"23","author":"Marijnen","year":"2005","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.canrad.2022.07.001_bib0125","doi-asserted-by":"crossref","first-page":"8697","DOI":"10.1200\/JCO.2005.02.9017","article-title":"Glimelius. Adverse effects of preoperative therapy for rectal cancer: long-term follow up of the Swedish Rectal Cancer trial","volume":"23","author":"Birgisson","year":"2005","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.canrad.2022.07.001_bib0130","article-title":"Mechanisms of local recurrence after rectal cancer resection. What can we learn from the Dutch TME trial?","volume":"17","author":"Beets","year":"2006","journal-title":"Ann Oncol"},{"key":"10.1016\/j.canrad.2022.07.001_bib0135","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1002\/bjs.5233","article-title":"Radiological findings do not support lateral residual tumour as a major cause of local recurrence of rectal cancer","volume":"93","author":"Syk","year":"2006","journal-title":"Br J Surg"},{"key":"10.1016\/j.canrad.2022.07.001_bib0140","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1016\/j.brachy.2005.03.006","article-title":"High dose rate endorectal brachytherapy in the treatment of locally advanced rectal carcinoma: technical aspects","volume":"4","author":"Vuong","year":"2005","journal-title":"Brachytherapy"},{"key":"10.1016\/j.canrad.2022.07.001_bib0145","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1016\/j.clon.2007.07.006","article-title":"High dose rate brachytherapy for patients with advanced resectable rectal cancer","volume":"19","author":"Vuong","year":"2007","journal-title":"Clin Oncol"},{"key":"10.1016\/j.canrad.2022.07.001_bib0150","doi-asserted-by":"crossref","first-page":"4620","DOI":"10.1200\/JCO.2006.06.7629","article-title":"Preoperative radiotherapy with or without concurrent fluorouracil and leucovorinin T3-4 rectal cancers: results of FFD 9203","volume":"24","author":"G\u00e9rard","year":"2006","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.canrad.2022.07.001_bib0155","doi-asserted-by":"crossref","first-page":"1731","DOI":"10.1056\/NEJMoa040694","article-title":"Preoperative versus postoperative chemoradiotherapy for rectal cancer","volume":"331","author":"Sauer","year":"2004","journal-title":"N Engl J Med"},{"key":"10.1016\/j.canrad.2022.07.001_bib0160","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/j.radonc.2020.11.008","article-title":"Optimizing treatment sequencing of chemotherapy for patients with rectal cancer: the KIR randomized phase II trial","volume":"155","author":"Garant","year":"2021","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.canrad.2022.07.001_bib0165","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/j.radonc.2005.09.001","article-title":"Primary radical external beam radiotherapy of rectal adenocarcinoma: long term outcome of 271 patients","volume":"77","author":"Wang","year":"2005","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.canrad.2022.07.001_bib0170","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1016\/j.ijrobp.2019.08.042","article-title":"Image guided adaptive endorectal brachytherapy in the non-operative management of patients with rectal cancer","volume":"105","author":"Garant","year":"2019","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.canrad.2022.07.001_bib0175","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1016\/j.radonc.2017.12.023","article-title":"Evaluation of clinical and endoscopic toxicity after external beam radiotherapy and endorectal brachytherapy in elderly patients with rectal cancer treated in the HERBERT study","volume":"126","author":"Rijkmans","year":"2018","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.canrad.2022.07.001_bib0180","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1016\/S1470-2045(15)00120-5","article-title":"High-dose chemoradiotherapy and watchful waiting for distal rectal cancer: a prospective observational study","volume":"16","author":"Appelt","year":"2015","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.canrad.2022.07.001_bib0185","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.ijrobp.2012.05.017","article-title":"Radiation dose-response model for locally advanced rectal cancer after preoperative chemoradiation therapy","volume":"85","author":"Appelt","year":"2013","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.canrad.2022.07.001_bib0190","doi-asserted-by":"crossref","first-page":"S76","DOI":"10.1016\/S0167-8140(21)00186-9","article-title":"PH-0162: Is there a radiation dose-response relationship for non-operative management of rectal cancer?","volume":"152","author":"Appelt","year":"2020","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.canrad.2022.07.001_bib0195","doi-asserted-by":"crossref","first-page":"3512","DOI":"10.1200\/JCO.2022.40.16_suppl.3512","article-title":"Contact x-ray brachytherapy (Papillon) in addition to chemoradiotherapy to improve organ preservation in early cT2-T3 rectal adenocarcinoma: the 3-year results of OPERA randomized trial (NCT02505750)","volume":"40","author":"G\u00e9rard","year":"2022","journal-title":"J Clin Oncol"},{"issue":"15","key":"10.1016\/j.canrad.2022.07.001_bib0200","article-title":"OC-0621 Interim safety analysis and preliminary results of the Morpheus phase III Study","volume":"14","author":"Garant","year":"2022","journal-title":"Cancers"}],"container-title":["Cancer\/Radioth\u00e9rapie"],"original-title":[],"language":"fr","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1278321822001536?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1278321822001536?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T12:35:08Z","timestamp":1761136508000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1278321822001536"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,10]]},"references-count":20,"journal-issue":{"issue":"6-7","published-print":{"date-parts":[[2022,10]]}},"alternative-id":["S1278321822001536"],"URL":"https:\/\/doi.org\/10.1016\/j.canrad.2022.07.001","relation":{},"ISSN":["1278-3218"],"issn-type":[{"value":"1278-3218","type":"print"}],"subject":[],"published":{"date-parts":[[2022,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Clinical applications of high dose rate endorectal brachytherapy for patients with rectal cancer","name":"articletitle","label":"Article Title"},{"value":"Cancer\/Radioth\u00e9rapie","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.canrad.2022.07.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Soci\u00e9t\u00e9 fran\u00e7aise de radioth\u00e9rapie oncologique (SFRO). Published by Elsevier Masson SAS. All rights reserved.","name":"copyright","label":"Copyright"}]}}