{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T00:16:21Z","timestamp":1761178581703,"version":"build-2065373602"},"reference-count":23,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.fr","em-consulte.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cancer\/Radioth\u00e9rapie"],"published-print":{"date-parts":[[2023,5]]},"DOI":"10.1016\/j.canrad.2022.10.002","type":"journal-article","created":{"date-parts":[[2023,4,22]],"date-time":"2023-04-22T20:22:01Z","timestamp":1682194921000},"page":"235-239","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Leiomyosarcoma of the lower rectum managed by radiotherapy and surgery: A case report and review of literature"],"prefix":"10.1016","volume":"27","author":[{"given":"A.","family":"Bennassi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Souhail","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Lo Cicero","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Durigova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Salati","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.canrad.2022.10.002_bib0120","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1007\/BF02616645","article-title":"Leiomyoma and leiomyosarcoma of the rectum","volume":"5","author":"Quan","year":"1962","journal-title":"Dis Colon Rectum"},{"key":"10.1016\/j.canrad.2022.10.002_bib0125","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1007\/BF02055476","article-title":"Sphincter preservation in rectal sarcoma","volume":"33","author":"Minsky","year":"1990","journal-title":"Dis Colon Rectum"},{"key":"10.1016\/j.canrad.2022.10.002_bib0130","doi-asserted-by":"crossref","first-page":"1618","DOI":"10.21037\/tcr.2019.06.17","article-title":"Multidisciplinary evaluation of locally advanced leiomyosarcoma in the lower rectum: a case report and literature review","volume":"8","author":"Xu","year":"2019","journal-title":"Transl Cancer Res"},{"key":"10.1016\/j.canrad.2022.10.002_bib0135","doi-asserted-by":"crossref","first-page":"1517","DOI":"10.1007\/BF02236730","article-title":"Surgical outcome after curative resection of rectal leiomyosarcoma","volume":"43","author":"Yeh","year":"2000","journal-title":"Dis Colon Rectum"},{"key":"10.1016\/j.canrad.2022.10.002_bib0140","doi-asserted-by":"crossref","first-page":"1296","DOI":"10.1007\/BF02234218","article-title":"Sphincter preservation of leiomyosarcoma of the rectum and anus with local excision and brachytherapy","volume":"42","author":"Grann","year":"1999","journal-title":"Dis Colon Rectum"},{"key":"10.1016\/j.canrad.2022.10.002_bib0145","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1046\/j.1440-1673.1999.00646.x","article-title":"Leiomyosarcoma of the rectum: what role does adjuvant therapy play?","volume":"43","author":"Kiffer","year":"1999","journal-title":"Australas Radiol"},{"key":"10.1016\/j.canrad.2022.10.002_bib0150","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1007\/BF01646866","article-title":"Leiomyosarcoma of the rectum and anus: a series of 22 cases","volume":"4","author":"Randleman","year":"1989","journal-title":"Int J Colorect Dis"},{"key":"10.1016\/j.canrad.2022.10.002_bib0155","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1007\/BF02555068","article-title":"Leiomyosarcoma of the rectum: report of a case and review of the literature","volume":"29","author":"Khalifa","year":"1986","journal-title":"Dis Colon Rectum"},{"key":"10.1016\/j.canrad.2022.10.002_bib0160","doi-asserted-by":"crossref","first-page":"100850","DOI":"10.1016\/j.adro.2021.100850","article-title":"Is 5 the new 25? Long-term oncologic outcomes from a phase II, prospective, 5-fraction preoperative radiation therapy trial in patients with localized soft tissue sarcoma","volume":"7","author":"Bedi","year":"2022","journal-title":"Adv Radiat Oncol"},{"key":"10.1016\/j.canrad.2022.10.002_bib0165","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/j.canrad.2021.11.023","article-title":"Conformal radiotherapy in management of soft tissue sarcoma in adults","volume":"26","author":"Le P\u00e9choux","year":"2022","journal-title":"Cancer Radiother"},{"key":"10.1016\/j.canrad.2022.10.002_bib0170","doi-asserted-by":"crossref","first-page":"459","DOI":"10.2478\/raon-2021-0038","article-title":"Hypofractionated preoperative radiotherapy for high risk soft tissue sarcomas in a geriatric patient population","volume":"55","author":"Potkrajcic","year":"2021","journal-title":"Radiol Oncol"},{"key":"10.1016\/j.canrad.2022.10.002_bib0175","doi-asserted-by":"crossref","first-page":"1274","DOI":"10.1016\/j.adro.2020.06.024","article-title":"Early outcomes of preoperative 5-fraction radiation therapy for soft tissue sarcoma followed by immediate surgical resection","volume":"5","author":"Parsai","year":"2020","journal-title":"Adv Radiat Oncol"},{"key":"10.1016\/j.canrad.2022.10.002_bib0180","doi-asserted-by":"crossref","first-page":"1621","DOI":"10.21873\/invivo.11646","article-title":"Hypofractionated accelerated chemo-radiotherapy (Chemo-HypoAR) with cisplatin and liposomal doxorubicin for the treatment of patients with uterine sarcomas","volume":"33","author":"Domoxoudis","year":"2019","journal-title":"In Vivo"},{"key":"10.1016\/j.canrad.2022.10.002_bib0185","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1002\/cncr.23592","article-title":"A systematic meta-analysis of randomized controlled trials of adjuvant chemotherapy for localized resectable soft-tissue sarcoma","volume":"113","author":"Pervaiz","year":"2008","journal-title":"Cancer"},{"key":"10.1016\/j.canrad.2022.10.002_bib0190","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1016\/S1470-2045(14)70063-4","article-title":"Doxorubicin alone versus intensified doxorubicin plus ifosfamide for first-line treatment of advanced or metastatic soft-tissue sarcoma: a randomised controlled phase 3 trial","volume":"15","author":"Judson","year":"2014","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.canrad.2022.10.002_bib0195","doi-asserted-by":"crossref","first-page":"2637","DOI":"10.1002\/cncr.32795","volume":"126","author":"D\u2019Ambrosio","year":"2020","journal-title":"Cancer"},{"key":"10.1016\/j.canrad.2022.10.002_bib0200","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1200\/JCO.2015.62.4734","article-title":"Efficacy and safety of trabectedin or dacarbazine for metastatic liposarcoma or leiomyosarcoma after failure of conventional chemotherapy: results of a phase III randomized multicenter clinical trial","volume":"34","author":"Demetri","year":"2016","journal-title":"JCO"},{"key":"10.1016\/j.canrad.2022.10.002_bib0205","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1002\/gcc.22318","article-title":"Targeted exome sequencing profiles genetic alterations in leiomyosarcoma","volume":"55","author":"Agaram","year":"2016","journal-title":"Genes Chromosom Cancer"},{"key":"10.1016\/j.canrad.2022.10.002_bib0210","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1038\/nm1560","article-title":"The AKT-mTOR pathway plays a critical role in the development of leiomyosarcomas","volume":"13","author":"Hernando","year":"2007","journal-title":"Nat Med"},{"key":"10.1016\/j.canrad.2022.10.002_bib0215","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1038\/bjc.1989.251","article-title":"Structural alterations of the RB1 gene in human soft tissue tumours","volume":"60","author":"Stratton","year":"1989","journal-title":"Br J Cancer"},{"key":"10.1016\/j.canrad.2022.10.002_bib0220","doi-asserted-by":"crossref","first-page":"1879","DOI":"10.1016\/S0140-6736(12)60651-5","article-title":"Pazopanib for metastatic soft-tissue sarcoma (PALETTE): a randomised, double-blind, placebo-controlled phase 3 trial","volume":"379","author":"van der Graaf","year":"2012","journal-title":"Lancet"},{"key":"10.1016\/j.canrad.2022.10.002_bib0225","doi-asserted-by":"crossref","first-page":"11005","DOI":"10.1200\/JCO.2016.34.15_suppl.11005","article-title":"Phase II study of anlotinib for treatment of advanced soft tissues sarcomas","volume":"34","author":"Chi","year":"2016","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.canrad.2022.10.002_bib0230","doi-asserted-by":"crossref","first-page":"339","DOI":"10.21037\/atm-21-49","article-title":"Real-world experience with pembrolizumab in patients with advanced soft tissue sarcoma","volume":"9","author":"Liu","year":"2021","journal-title":"Ann Transl Med"}],"container-title":["Cancer\/Radioth\u00e9rapie"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1278321823000537?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1278321823000537?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T12:35:53Z","timestamp":1761136553000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1278321823000537"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5]]},"references-count":23,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2023,5]]}},"alternative-id":["S1278321823000537"],"URL":"https:\/\/doi.org\/10.1016\/j.canrad.2022.10.002","relation":{},"ISSN":["1278-3218"],"issn-type":[{"type":"print","value":"1278-3218"}],"subject":[],"published":{"date-parts":[[2023,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Leiomyosarcoma of the lower rectum managed by radiotherapy and surgery: A case report and review of literature","name":"articletitle","label":"Article Title"},{"value":"Cancer\/Radioth\u00e9rapie","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.canrad.2022.10.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Soci\u00e9t\u00e9 fran\u00e7aise de radioth\u00e9rapie oncologique (SFRO). Published by Elsevier Masson SAS. All rights reserved.","name":"copyright","label":"Copyright"}]}}