{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T17:18:57Z","timestamp":1747156737951,"version":"3.40.5"},"reference-count":39,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.fr","em-consulte.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cancer\/Radioth\u00e9rapie"],"published-print":{"date-parts":[[2024,12]]},"DOI":"10.1016\/j.canrad.2024.05.008","type":"journal-article","created":{"date-parts":[[2024,11,8]],"date-time":"2024-11-08T06:50:26Z","timestamp":1731048626000},"page":"686-692","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Defining the potential for sexual structures-sparing for prostate cancer external beam radiotherapy: A dosimetric study"],"prefix":"10.1016","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9589-4873","authenticated-orcid":false,"given":"Jennifer","family":"Le Guevelou","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ayad","family":"Houssayni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"St\u00e9phane","family":"Key","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Axel","family":"Largent","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Caroline","family":"Lafond","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oscar","family":"Acosta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antoine","family":"Simon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Renaud","family":"de Crevoisier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana\u00efs","family":"Barateau","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.canrad.2024.05.008_bib0200","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/j.eururo.2020.09.042","article-title":"EAU-EANM-ESTRO-ESUR-SIOG Guidelines on prostate cancer\u20142020 update. Part 1: screening, diagnosis, and local treatment with curative intent","volume":"79","author":"Mottet","year":"2021","journal-title":"Eur Urol"},{"key":"10.1016\/j.canrad.2024.05.008_bib0205","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.ijrobp.2021.07.004","article-title":"Quality of life implications of dose-escalated external beam radiation for localized prostate cancer: results of a prospective randomized phase 3 clinical trial, NRG\/RTOG 0126","volume":"112","author":"Hall","year":"2022","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.canrad.2024.05.008_bib0210","doi-asserted-by":"crossref","first-page":"1056","DOI":"10.1016\/j.ijrobp.2010.03.049","article-title":"70 Gy versus 80 Gy in localized prostate cancer: 5-year results of GETUG 06 randomized trial","volume":"80","author":"Beckendorf","year":"2011","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.canrad.2024.05.008_bib0215","doi-asserted-by":"crossref","first-page":"2108","DOI":"10.1111\/jsm.12215","article-title":"Influence of vascular comorbidities and race on erectile dysfunction after prostate cancer radiotherapy","volume":"10","author":"Wang","year":"2013","journal-title":"J Sex Med"},{"key":"10.1016\/j.canrad.2024.05.008_bib0220","doi-asserted-by":"crossref","first-page":"1358","DOI":"10.1093\/jnci\/djh259","article-title":"Five-year outcomes after prostatectomy or radiotherapy for prostate cancer: the prostate cancer outcomes study","volume":"96","author":"Potosky","year":"2004","journal-title":"J Natl Cancer Inst"},{"key":"10.1016\/j.canrad.2024.05.008_bib0225","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1111\/j.1743-6109.2005.20362.x","article-title":"The hemodynamics of erectile dysfunction following external beam radiation for prostate cancer","volume":"2","author":"Mulhall","year":"2005","journal-title":"J Sex Med"},{"key":"10.1016\/j.canrad.2024.05.008_bib0230","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/S0360-3016(97)00554-3","article-title":"Elucidating the etiology of erectile dysfunction after definitive therapy for prostatic cancer","volume":"40","author":"Zelefsky","year":"1998","journal-title":"Int J Radiat Oncol"},{"key":"10.1016\/j.canrad.2024.05.008_bib0235","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1007\/s00066-016-0964-1","article-title":"Baseline status and dose to the penile bulb predict impotence 1 year after radiotherapy for prostate cancer","volume":"192","author":"Cozzarini","year":"2016","journal-title":"Strahlenther Onkol"},{"key":"10.1016\/j.canrad.2024.05.008_bib0240","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1016\/S0090-4295(01)00940-2","article-title":"Dose of radiation received by the bulb of the penis correlates with risk of impotence after three-dimensional conformal radiotherapy for prostate cancer","volume":"57","author":"Fisch","year":"2001","journal-title":"Urology"},{"key":"10.1016\/j.canrad.2024.05.008_bib0245","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.ijrobp.2020.01.022","article-title":"Erectile dysfunction and absorbed dose to penile base structures in a randomized trial comparing ultrahypofractionated and conventionally fractionated radiation therapy for prostate cancer","volume":"107","author":"Rasmusson","year":"2020","journal-title":"Int J Radiat Oncol"},{"key":"10.1016\/j.canrad.2024.05.008_bib0250","doi-asserted-by":"crossref","first-page":"1351","DOI":"10.1016\/j.ijrobp.2004.05.026","article-title":"Penile bulb dose and impotence after three-dimensional conformal radiotherapy for prostate cancer on RTOG 9406: findings from a prospective, multi-institutional, phase I\/II dose-escalation study","volume":"60","author":"Roach","year":"2004","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.canrad.2024.05.008_bib0255","doi-asserted-by":"crossref","first-page":"1357","DOI":"10.1016\/j.ijrobp.2004.05.030","article-title":"Radiation dose delivered to the proximal penis as a predictor of the risk of erectile dysfunction after three-dimensional conformal radiotherapy for localized prostate cancer","volume":"60","author":"Wernicke","year":"2004","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.canrad.2024.05.008_bib0260","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/j.radonc.2006.07.037","article-title":"Evaluating the relationship between erectile dysfunction and dose received by the penile bulb: using data from a randomised controlled trial of conformal radiotherapy in prostate cancer (MRC RT01, ISRCTN47772397)","volume":"80","author":"Mangar","year":"2006","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.canrad.2024.05.008_bib0265","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1016\/j.ijrobp.2005.02.036","article-title":"Functional anatomy of the prostate: implications for treatment planning","volume":"63","author":"McLaughlin","year":"2005","journal-title":"Int J Radiat Oncol"},{"key":"10.1016\/j.canrad.2024.05.008_bib0270","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.ejmp.2019.04.008","article-title":"Dose optimization and endorectal balloon for internal pudendal arteries sparing in prostate SBRT","volume":"61","author":"Jaccard","year":"2019","journal-title":"Phys Med"},{"key":"10.1016\/j.canrad.2024.05.008_bib0275","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1016\/j.eururo.2017.02.007","article-title":"Vessel-sparing radiotherapy for localized prostate cancer to preserve erectile function: a single-arm phase 2 trial","volume":"72","author":"Spratt","year":"2017","journal-title":"Eur Urol"},{"key":"10.1016\/j.canrad.2024.05.008_bib0280","doi-asserted-by":"crossref","first-page":"S130","DOI":"10.1016\/j.ijrobp.2009.04.094","article-title":"Radiation dose-volume effects and the penile bulb","volume":"76","author":"Roach","year":"2010","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.canrad.2024.05.008_bib0285","doi-asserted-by":"crossref","first-page":"1371","DOI":"10.1016\/S0022-5347(05)65303-7","article-title":"Erectile dysfunction after radical prostatectomy: hemodynamic profiles and their correlation with the recovery of erectile function","volume":"167","author":"Mulhall","year":"2002","journal-title":"J Urol"},{"key":"10.1016\/j.canrad.2024.05.008_bib0290","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.ijrobp.2004.04.070","article-title":"Vessel-sparing prostate radiotherapy: dose limitation to critical erectile vascular structures (internal pudendal artery and corpus cavernosum) defined by MRI","volume":"61","author":"McLaughlin","year":"2005","journal-title":"Int J Radiat Oncol"},{"key":"10.1016\/j.canrad.2024.05.008_bib0295","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/j.phro.2021.09.002","article-title":"Adaptive magnetic resonance-guided neurovascular-sparing radiotherapy for preservation of erectile function in prostate cancer patients","volume":"20","author":"Teunissen","year":"2021","journal-title":"Phys Imaging Radiat Oncol"},{"key":"10.1016\/j.canrad.2024.05.008_bib0300","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.radonc.2018.01.014","article-title":"ESTRO ACROP consensus guideline on CT- and MRI-based target volume delineation for primary radiation therapy of localized prostate cancer","volume":"127","author":"Salembier","year":"2018","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.canrad.2024.05.008_bib0305","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/j.ejmp.2021.07.027","article-title":"Deep learning methods to generate synthetic CT from MRI in radiotherapy: a literature review","volume":"89","author":"Boulanger","year":"2021","journal-title":"Phys Med"},{"key":"10.1016\/j.canrad.2024.05.008_bib0310","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1016\/j.ijrobp.2018.10.002","article-title":"Pseudo-CT generation for MRI-only radiation therapy treatment planning: comparison among patch-based, atlas-based, and bulk density methods","volume":"103","author":"Largent","year":"2019","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.canrad.2024.05.008_bib0315","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1016\/j.ijrobp.2019.08.049","article-title":"Comparison of deep learning-based and patch-based methods for pseudo-CT generation in MRI-based prostate dose planning","volume":"105","author":"Largent","year":"2019","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.canrad.2024.05.008_bib0320","doi-asserted-by":"crossref","first-page":"e353","DOI":"10.1016\/j.ijrobp.2012.01.023","article-title":"Pelvic normal tissue contouring guidelines for radiation therapy: a Radiation Therapy Oncology Group consensus panel atlas","volume":"83","author":"Gay","year":"2012","journal-title":"Int J Radiat Oncol"},{"key":"10.1016\/j.canrad.2024.05.008_bib0325","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/j.canrad.2021.11.017","article-title":"External radiotherapy for prostatic cancers","volume":"26","author":"de Crevoisier","year":"2022","journal-title":"Cancer Radiother"},{"key":"10.1016\/j.canrad.2024.05.008_bib0330","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1016\/j.euo.2023.08.003","article-title":"Sexual structure sparing for prostate cancer radiotherapy: a systematic review","volume":"7","author":"Le Guevelou","year":"2023","journal-title":"Eur Urol Oncol"},{"key":"10.1016\/j.canrad.2024.05.008_bib0335","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1007\/s00066-012-0227-8","article-title":"Erectile dysfunction after prostate three-dimensional conformal radiation therapy: correlation with the dose to the penile bulb","volume":"188","author":"Magli","year":"2012","journal-title":"Strahlenther Onkol"},{"key":"10.1016\/j.canrad.2024.05.008_bib0340","doi-asserted-by":"crossref","first-page":"1074","DOI":"10.1016\/j.ijrobp.2022.12.008","article-title":"Long-term results of a phase 3 randomized prospective trial of erectile tissue\u2013sparing intensity modulated radiation therapy for men with clinically localized prostate cancer","volume":"115","author":"Zhang","year":"2023","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.canrad.2024.05.008_bib0345","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1016\/j.ijrobp.2003.12.028","article-title":"Erectile dysfunction and radiation dose to penile base structures: a lack of correlation","volume":"59","author":"Selek","year":"2004","journal-title":"Int J Radiat Oncol"},{"key":"10.1016\/j.canrad.2024.05.008_bib0350","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1016\/j.ijrobp.2007.10.052","article-title":"Dose\u2013volume parameters of the corpora cavernosa do not correlate with erectile dysfunction after external beam radiotherapy for prostate cancer: results from a dose\u2013escalation trial","volume":"71","author":"van der Wielen","year":"2008","journal-title":"Int J Radiat Oncol"},{"key":"10.1016\/j.canrad.2024.05.008_bib0355","doi-asserted-by":"crossref","first-page":"2388","DOI":"10.1111\/jsm.13031","article-title":"Radiation dose to the penile structures and patient-reported sexual dysfunction in long-term prostate cancer survivors","volume":"12","author":"Thor","year":"2015","journal-title":"J Sex Med"},{"key":"10.1016\/j.canrad.2024.05.008_bib0360","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1016\/j.ijrobp.2023.12.037","article-title":"Urethra-sparing prostate cancer stereotactic body radiation therapy: sexual function and radiation dose to the penile bulb, the crura, and the internal pudendal arteries from a randomized phase 2 trial","volume":"119","author":"Achard","year":"2024","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.canrad.2024.05.008_bib0365","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1016\/j.eururo.2017.02.007","article-title":"Vessel-sparing radiotherapy for localized prostate cancer to preserve erectile function: a single-arm phase 2 trial","volume":"72","author":"Spratt","year":"2017","journal-title":"Eur Urol"},{"key":"10.1016\/j.canrad.2024.05.008_bib0370","doi-asserted-by":"crossref","first-page":"20160877","DOI":"10.1259\/bjr.20160877","article-title":"Prospective evaluation of a specific technique of sexual function preservation in external beam radiotherapy for prostate cancer","volume":"90","author":"Samlali","year":"2017","journal-title":"Br J Radiol"},{"key":"10.1016\/j.canrad.2024.05.008_bib0375","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1111\/1754-9485.12844","article-title":"Multiobserver contouring of male pelvic anatomy: highly variable agreement across conventional and emerging structures of interest","volume":"63","author":"Roach","year":"2019","journal-title":"J Med Imaging Radiat Oncol"},{"key":"10.1016\/j.canrad.2024.05.008_bib0380","doi-asserted-by":"crossref","first-page":"e14179","DOI":"10.1002\/acm2.14179","article-title":"The impact of margin reduction on radiation dose distribution of ultra-hypofractionated prostate radiotherapy utilizing a 1.5-T MR-linac","volume":"25","author":"Onal","year":"2024","journal-title":"J Appl Clin Med Phys"},{"key":"10.1016\/j.canrad.2024.05.008_bib0385","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1001\/jamaoncol.2022.6558","article-title":"Magnetic resonance imaging-guided vs. computed tomography-guided stereotactic body radiotherapy for prostate cancer: the MIRAGE randomized clinical trial","volume":"9","author":"Kishan","year":"2023","journal-title":"JAMA Oncol"},{"key":"10.1016\/j.canrad.2024.05.008_bib0390","doi-asserted-by":"crossref","first-page":"6537","DOI":"10.1002\/mp.15150","article-title":"Deep learning based synthetic-CT generation in radiotherapy and PET: a review","volume":"48","author":"Spadea","year":"2021","journal-title":"Med Phys"}],"container-title":["Cancer\/Radioth\u00e9rapie"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1278321824001999?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1278321824001999?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T12:16:56Z","timestamp":1733055416000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1278321824001999"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12]]},"references-count":39,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2024,12]]}},"alternative-id":["S1278321824001999"],"URL":"https:\/\/doi.org\/10.1016\/j.canrad.2024.05.008","relation":{},"ISSN":["1278-3218"],"issn-type":[{"type":"print","value":"1278-3218"}],"subject":[],"published":{"date-parts":[[2024,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Defining the potential for sexual structures-sparing for prostate cancer external beam radiotherapy: A dosimetric study","name":"articletitle","label":"Article Title"},{"value":"Cancer\/Radioth\u00e9rapie","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.canrad.2024.05.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Soci\u00e9t\u00e9 fran\u00e7aise de radioth\u00e9rapie oncologique (SFRO). Published by Elsevier Masson SAS. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}