{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T06:37:56Z","timestamp":1787726276483,"version":"build-2784847793"},"reference-count":60,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100002383","name":"King Saud University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002383","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Carbohydrate Polymers"],"published-print":{"date-parts":[[2021,3]]},"DOI":"10.1016\/j.carbpol.2020.117484","type":"journal-article","created":{"date-parts":[[2020,12,5]],"date-time":"2020-12-05T01:59:30Z","timestamp":1607133570000},"page":"117484","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":90,"special_numbering":"C","title":["Wound dressing of chitosan-based-crosslinked gelatin\/ polyvinyl pyrrolidone embedded silver nanoparticles, for targeting multidrug resistance microbes"],"prefix":"10.1016","volume":"255","author":[{"given":"M.R.","family":"El-Aassar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Omar M.","family":"Ibrahim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Moustafa M.G.","family":"Fouda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hala","family":"Fakhry","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jamaan","family":"Ajarem","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saleh N.","family":"Maodaa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed A.","family":"Allam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elsayed E.","family":"Hafez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"11","key":"10.1016\/j.carbpol.2020.117484_bib0005","first-page":"1","article-title":"Anti-bacterial activity of different soaps available in local market of rawalpindi (Pakistan) against daily encountered bacteria","volume":"7","author":"Abbas","year":"2016","journal-title":"Pharmaceutica Analytica Acta"},{"key":"10.1016\/j.carbpol.2020.117484_bib0010","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.ijbiomac.2015.06.027","article-title":"Chitin and chitosan from Brazilian Atlantic Coast: Isolation, characterization and antibacterial activity","volume":"80","author":"Abdel-Rahman","year":"2015","journal-title":"International Journal of Biological Macromolecules"},{"key":"10.1016\/j.carbpol.2020.117484_bib0015","doi-asserted-by":"crossref","first-page":"1008","DOI":"10.1016\/j.ijbiomac.2019.04.134","article-title":"Assessment of silver nanoparticles decorated starch and commercial zinc nanoparticles with respect to their genotoxicity on onion","volume":"133","author":"Abdelsalam","year":"2019","journal-title":"International Journal of Biological Macromolecules"},{"issue":"3","key":"10.1016\/j.carbpol.2020.117484_bib0020","doi-asserted-by":"crossref","DOI":"10.1088\/2057-1976\/aaaafe","article-title":"Chitosan-silver nanoparticles as an approach to control bacterial proliferation, spores and antibiotic-resistant bacteria","volume":"4","author":"Alfaro-Gonz\u00e1lez","year":"2018","journal-title":"Biomedical Physics & Engineering Express"},{"issue":"1","key":"10.1016\/j.carbpol.2020.117484_bib0025","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.ijbiomac.2009.03.010","article-title":"Chitosan topical gel formulation in the management of burn wounds","volume":"45","author":"Alsarra","year":"2009","journal-title":"International Journal of Biological Macromolecules"},{"key":"10.1016\/j.carbpol.2020.117484_bib0030","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1016\/j.ijbiomac.2017.06.010","article-title":"Hydrogel beads bio-nanocomposite based on Kappa-Carrageenan and green synthesized silver nanoparticles for biomedical applications","volume":"104","author":"Azizi","year":"2017","journal-title":"International Journal of Biological Macromolecules"},{"key":"10.1016\/j.carbpol.2020.117484_bib0035","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1016\/j.lwt.2006.07.008","volume":"40","author":"Babak","year":"2007","journal-title":"LWT"},{"issue":"4","key":"10.1016\/j.carbpol.2020.117484_bib0040","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1002\/(SICI)1097-0169(1996)35:4<358::AID-CM7>3.0.CO;2-2","article-title":"Perfect wound healing in the keratin 8 deficient mouse embryo","volume":"35","author":"Brock","year":"1996","journal-title":"Cell Motility and the Cytoskeleton"},{"issue":"17","key":"10.1016\/j.carbpol.2020.117484_bib0045","doi-asserted-by":"crossref","first-page":"2871","DOI":"10.1016\/S0142-9612(03)00117-0","article-title":"Study on physical properties and nerve cell affinity of composite films from chitosan and gelatin solutions","volume":"24","author":"Cheng","year":"2003","journal-title":"Biomaterials"},{"key":"10.1016\/j.carbpol.2020.117484_bib0050","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/j.carbpol.2017.09.055","article-title":"Chitosan as an effective inhibitor of multidrug resistant Acinetobacter baumannii","volume":"178","author":"Costa","year":"2017","journal-title":"Carbohydrate Polymers"},{"key":"10.1016\/j.carbpol.2020.117484_bib0055","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1016\/j.carbpol.2018.08.083","article-title":"Exploring chitosan nanoparticles as effective inhibitors of antibiotic resistant skin microorganisms\u2013From in vitro to ex vitro testing","volume":"201","author":"Costa","year":"2018","journal-title":"Carbohydrate Polymers"},{"key":"10.1016\/j.carbpol.2020.117484_bib0060","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1016\/j.jtice.2018.07.020","article-title":"Eco-friendly method for silver nanoparticles immobilized decorated silica: Synthesis & characterization and preliminary antibacterial activity","volume":"95","author":"Dahlous","year":"2019","journal-title":"Journal of the Taiwan Institute of Chemical Engineers"},{"issue":"7","key":"10.1016\/j.carbpol.2020.117484_bib0065","doi-asserted-by":"crossref","first-page":"358","DOI":"10.12968\/bjon.1993.2.7.358","article-title":"Role of hydrocolloids in wound management","volume":"2","author":"Dealey","year":"1993","journal-title":"British Journal Nursing"},{"issue":"4","key":"10.1016\/j.carbpol.2020.117484_bib0070","doi-asserted-by":"crossref","first-page":"22","DOI":"10.7603\/s40681-015-0022-9","article-title":"Wound dressings - A review","volume":"5","author":"Dhivya","year":"2015","journal-title":"BioMedicine"},{"key":"10.1016\/j.carbpol.2020.117484_bib0075","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1016\/j.ijbiomac.2015.03.055","article-title":"Controlled drug release from cross-linked \u03ba-carrageenan\/hyaluronic acid membranes","volume":"77","author":"El-Aassar","year":"2015","journal-title":"International Journal of Biological Macromolecules"},{"key":"10.1016\/j.carbpol.2020.117484_bib0080","doi-asserted-by":"crossref","DOI":"10.1016\/j.carbpol.2020.116175","article-title":"Wound healing of nanofiber comprising Polygalacturonic\/Hyaluronic acid embedded silver nanoparticles: In-vitro and in-vivo studies","volume":"238","author":"El-Aassar","year":"2020","journal-title":"Carbohydrate Polymers"},{"issue":"643","key":"10.1016\/j.carbpol.2020.117484_bib0085","article-title":"Biogenically synthesized polysaccharides-capped silver nanoparticles: Immunomodulatory and antibacterial potentialities against resistant Pseudomonas aeruginosa","volume":"8","author":"El-Deeb","year":"2020","journal-title":"Frontiers in Bioengineering and Biotechnology"},{"key":"10.1016\/j.carbpol.2020.117484_bib0090","doi-asserted-by":"crossref","first-page":"1466","DOI":"10.1016\/j.ijbiomac.2014.10.051","article-title":"Synthesis and antibacterial of carboxymethyl starch-grafted poly(vinyl imidazole) against some plant pathogens","volume":"72","author":"El-Hamshary","year":"2015","journal-title":"International Journal of Biological Macromolecules"},{"issue":"3","key":"10.1016\/j.carbpol.2020.117484_bib0095","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.1016\/j.jconrel.2013.09.019","article-title":"Gelatin-based nanoparticles as drug and gene delivery systems: Reviewing three decades of research","volume":"172","author":"Elzoghby","year":"2013","journal-title":"Journal of Controlled Release"},{"issue":"8","key":"10.1016\/j.carbpol.2020.117484_bib0100","doi-asserted-by":"crossref","first-page":"1676","DOI":"10.1007\/s12221-015-5197-x","article-title":"Room temperature synthesis of metallic nanosilver using acacia to impart durable biocidal effect on cotton fabrics","volume":"16","author":"Emam","year":"2015","journal-title":"Fibers and Polymers"},{"issue":"11","key":"10.1016\/j.carbpol.2020.117484_bib0105","doi-asserted-by":"crossref","first-page":"7687","DOI":"10.1073\/pnas.122108599","article-title":"The evolutionary history of methicillin-resistant Staphylococcus aureus (MRSA)","volume":"99","author":"Enright","year":"2002","journal-title":"Proceedings of the National Academy of Sciences"},{"key":"10.1016\/j.carbpol.2020.117484_bib0110","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/j.ijbiomac.2014.11.040","article-title":"k-Carrageenan\/poly vinyl pyrollidone\/polyethylene glycol\/silver nanoparticles film for biomedical application","volume":"74","author":"Fouda","year":"2015","journal-title":"International Journal of Biological Macromolecules"},{"issue":"1-2","key":"10.1016\/j.carbpol.2020.117484_bib0115","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.ijpharm.2005.12.028","article-title":"Antimycotic influence of \u03b2-cyclodextrin complexes - In vitro measurements using laser nephelometry in microtiter plates","volume":"311","author":"Fouda","year":"2006","journal-title":"International Journal of Pharmaceutics"},{"issue":"1","key":"10.1016\/j.carbpol.2020.117484_bib0120","doi-asserted-by":"crossref","first-page":"5058","DOI":"10.1038\/s41598-018-23378-3","article-title":"Electrospinning over solvent casting: Tuning of mechanical properties of membranes","volume":"8","author":"Ghosal","year":"2018","journal-title":"Scientific Reports"},{"key":"10.1016\/j.carbpol.2020.117484_bib0125","doi-asserted-by":"crossref","DOI":"10.1016\/j.carbpol.2020.117119","article-title":"Strontium ion cross-linked alginate-g-poly (PEGMA) xerogels for wound healing applications: In vitro studies","volume":"251","author":"Gp","year":"2021","journal-title":"Carbohydrate Polymers"},{"key":"10.1016\/j.carbpol.2020.117484_bib0130","first-page":"1","article-title":"Hydrocolloids: Frequently asked questions","volume":"1","author":"Heenan","year":"1998","journal-title":"World Wide Wounds"},{"issue":"1","key":"10.1016\/j.carbpol.2020.117484_bib0135","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s11671-018-2482-9","article-title":"Antibacterial activity of in situ prepared chitosan\/silver nanoparticles solution against methicillin-resistant strains of Staphylococcus aureus","volume":"13","author":"Holubnycha","year":"2018","journal-title":"Nanoscale Research Letters"},{"key":"10.1016\/j.carbpol.2020.117484_bib0140","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijbiomac.2019.12.266","article-title":"Alginate based tamoxifen\/metal dual core-folate decorated shell: Nanocomposite targeted therapy for breast cancer via ROS-driven NF-\u03baB pathway modulation","author":"Ibrahim","year":"2020","journal-title":"International Journal of Biological Macromolecules"},{"issue":"3","key":"10.1016\/j.carbpol.2020.117484_bib0145","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1016\/j.biotechadv.2011.01.005","article-title":"Biomaterials based on chitin and chitosan in wound dressing applications","volume":"29","author":"Jayakumar","year":"2011","journal-title":"Biotechnology Advances"},{"issue":"6","key":"10.1016\/j.carbpol.2020.117484_bib0150","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1128\/AAC.31.6.883","article-title":"Prevalence of macrolides-lincosamides-streptogramin B resistance and erm gene classes among clinical strains of staphylococci and streptococci","volume":"31","author":"Jenssen","year":"1987","journal-title":"Antimicrobial Agents and Chemotherapy"},{"issue":"3","key":"10.1016\/j.carbpol.2020.117484_bib0155","first-page":"303","article-title":"Mechanical, bioadhesive strength and biological evaluations of chitosan films for wound dressing","volume":"3","author":"Khan","year":"2000","journal-title":"Journal of Pharmacy & Pharmaceutical Sciences"},{"key":"10.1016\/j.carbpol.2020.117484_bib0160","doi-asserted-by":"crossref","first-page":"1121","DOI":"10.3389\/fphar.2019.01121","article-title":"Anti-methicillin resistant Staphylococcus aureus (MRSA) nanoantibiotics","volume":"10","author":"Labreure","year":"2019","journal-title":"Frontiers in Pharmacology"},{"issue":"5","key":"10.1016\/j.carbpol.2020.117484_bib0165","first-page":"269","article-title":"The properties of hydrogel dressings and their impact on wound healing","volume":"19","author":"Lay-Flurrie","year":"2004","journal-title":"Journal of Professional Nursing"},{"issue":"4","key":"10.1016\/j.carbpol.2020.117484_bib0170","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1086\/324626","article-title":"Mechanisms of resistance to macrolides and lincosamides: Nature of the resistance elements and their clinical implications","volume":"34","author":"Leclercq","year":"2002","journal-title":"Clinical Infectious Diseases"},{"issue":"3","key":"10.1016\/j.carbpol.2020.117484_bib0175","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1111\/j.1469-0691.2011.03570.x","article-title":"Multidrug-resistant, extensively drug-resistant and pandrug-resistant bacteria: An international expert proposal for interim standard definitions for acquired resistance","volume":"18","author":"Magiorakos","year":"2012","journal-title":"Clinical Microbiology and Infection"},{"issue":"6","key":"10.1016\/j.carbpol.2020.117484_bib0180","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.1016\/S0142-9612(02)00442-8","article-title":"Structure and properties of bilayer chitosan-gelatin scaffolds","volume":"24","author":"Mao","year":"2003","journal-title":"Biomaterials"},{"issue":"4","key":"10.1016\/j.carbpol.2020.117484_bib0185","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1016\/j.carbpol.2006.07.007","article-title":"Effects of molecular weight and deacetylation degree of chitin\/chitosan on wound healing","volume":"67","author":"Minagawa","year":"2007","journal-title":"Carbohydrate Polymers"},{"key":"10.1016\/j.carbpol.2020.117484_bib0190","first-page":"765","article-title":"Identification of group B streptococci using 16S rRNA, cfb, scpB, and atr genes in pregnant women by PCR","author":"Mousavi","year":"2016","journal-title":"Acta Medica Iranica"},{"issue":"1\u20132","key":"10.1016\/j.carbpol.2020.117484_bib0195","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/S0168-1605(01)00717-6","article-title":"Antibacterial activity of chitosans and chitosan oligomers with different molecular weights","volume":"74","author":"No","year":"2002","journal-title":"International Journal of Food Microbiology"},{"issue":"15","key":"10.1016\/j.carbpol.2020.117484_bib0200","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1016\/0142-9612(94)90272-0","article-title":"Chitosan-mediated stimulation of macrophage function","volume":"15","author":"Peluso","year":"1994","journal-title":"Biomaterials"},{"issue":"12","key":"10.1016\/j.carbpol.2020.117484_bib0205","doi-asserted-by":"crossref","first-page":"5715","DOI":"10.1128\/JCM.42.12.5715-5721.2004","article-title":"Phenotypic and molecular detection of CTX-M-beta-lactamases produced by Escherichia coli and Klebsiella spp","volume":"42","author":"Pitout","year":"2004","journal-title":"Journal of Clinical Microbiology"},{"issue":"3","key":"10.1016\/j.carbpol.2020.117484_bib0210","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1128\/AAC.44.3.622-632.2000","article-title":"Biochemical sequence analyses of GES-1, a novel class A extended-spectrum beta-lactamase, and the class 1 integron In52 from Klebsiella pneumoniae","volume":"44","author":"Poirel","year":"2000","journal-title":"Antimicrobial Agents and Chemotherapy"},{"key":"10.1016\/j.carbpol.2020.117484_bib0215","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/j.ijbiomac.2014.01.050","article-title":"Synthesis, characterization and antibacterial activity of new fluorescent chitosan derivatives","volume":"65","author":"P\u0159ichystalov\u00e1","year":"2014","journal-title":"International Journal of Biological Macromolecules"},{"key":"10.1016\/j.carbpol.2020.117484_bib0220","doi-asserted-by":"crossref","DOI":"10.1016\/j.carbpol.2019.115606","article-title":"Preparation of chitosan-based composites with urethane cross linkage and evaluation of their properties for using as wound healing dressing","volume":"230","author":"Rahmani","year":"2020","journal-title":"Carbohydrate Polymers"},{"key":"10.1016\/j.carbpol.2020.117484_bib0225","series-title":"Encyclopedia of polymer science and engineering","first-page":"488","article-title":"Treatise on collagen. Gelatin","author":"Ramachandran","year":"1967"},{"key":"10.1016\/j.carbpol.2020.117484_bib0230","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1016\/j.mayocp.2011.12.003","article-title":"Mechanisms of resistance and clinical relevance of resistance to \u03b2-lactams, glycopeptides, and fluoroquinolones","volume":"Vol. 87","author":"Rice","year":"2012","journal-title":"Mayo Clinic Proceedings"},{"issue":"4","key":"10.1016\/j.carbpol.2020.117484_bib0235","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1080\/10837450701366903","article-title":"Wound dressings based on chitosans and hyaluronic acid for the release of chlorhexidine diacetate in skin ulcer therapy","volume":"12","author":"Rossi","year":"2007","journal-title":"Pharmaceutical Development and Technology"},{"issue":"11","key":"10.1016\/j.carbpol.2020.117484_bib0240","doi-asserted-by":"crossref","first-page":"1908","DOI":"10.1021\/acs.jchemed.5b00099","article-title":"Fabrication of polyvinylpyrrolidone micro-\/nanostructures utilizing microcontact printing","volume":"92","author":"Sanders","year":"2015","journal-title":"Journal of Chemical Education"},{"issue":"6","key":"10.1016\/j.carbpol.2020.117484_bib0245","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.1080\/21691401.2016.1203795","article-title":"Low-cost and eco-friendly green synthesis of silver nanoparticles using Prunus japonica (Rosaceae) leaf extract and their antibacterial, antioxidant properties","volume":"45","author":"Saravanakumar","year":"2017","journal-title":"Artificial Cells, Nanomedicine, and Biotechnology"},{"issue":"1","key":"10.1016\/j.carbpol.2020.117484_bib0250","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1186\/s13287-019-1203-3","article-title":"Skin tissue regeneration for burn injury","volume":"10","author":"Shpichka","year":"2019","journal-title":"Stem Cell Research & Therapy"},{"key":"10.1016\/j.carbpol.2020.117484_bib0255","series-title":"Solvent cast technology\u2013a versatile tool for thin film production. In scattering methods and the properties of polymer materials","first-page":"1","author":"Siemann","year":"2005"},{"key":"10.1016\/j.carbpol.2020.117484_bib0260","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/j.carbpol.2018.02.079","article-title":"Chitosan\/pvp-based mucoadhesive membranes as a promising delivery system of betamethasone-17-valerate for aphthous stomatitis","volume":"190","author":"Siz\u00edlio","year":"2018","journal-title":"Carbohydrate Polymers"},{"issue":"3","key":"10.1016\/j.carbpol.2020.117484_bib0265","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1097\/00006454-200103000-00006","article-title":"Antibiotic-resistant bacteria in pediatric chronic sinusitis","volume":"20","author":"Slack","year":"2001","journal-title":"The Pediatric Infectious Disease Journal"},{"key":"10.1016\/j.carbpol.2020.117484_bib0270","series-title":"Medicinal plants and traditional medicine in Africa","author":"Sofowora","year":"1982"},{"issue":"1","key":"10.1016\/j.carbpol.2020.117484_bib0275","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1038\/s41429-018-0111-6","article-title":"Augmented antibacterial activity of ampicillin with silver nanoparticles against methicillin-resistant Staphylococcus aureus (MRSA)","volume":"72","author":"Surwade","year":"2019","journal-title":"The Journal of Antibiotics"},{"issue":"7","key":"10.1016\/j.carbpol.2020.117484_bib0280","doi-asserted-by":"crossref","first-page":"2562","DOI":"10.1016\/j.actbio.2010.01.002","article-title":"Antibacterial action of a novel functionalized chitosan-arginine against gram-negative bacteria","volume":"6","author":"Tang","year":"2010","journal-title":"Acta Biomaterialia"},{"key":"10.1016\/j.carbpol.2020.117484_bib0285","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/j.reactfunctpolym.2016.04.008","article-title":"Preparation and characterization of porous scaffolds from chitosan-collagen-gelatin composite","volume":"103","author":"Tylingo","year":"2016","journal-title":"Reactive & Functional Polymers"},{"issue":"2","key":"10.1016\/j.carbpol.2020.117484_bib0290","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/S0169-409X(01)00189-2","article-title":"Topical formulations and wound healing applications of chitosan","volume":"52","author":"Ueno","year":"2001","journal-title":"Advanced Drug Delivery Reviews"},{"issue":"3","key":"10.1016\/j.carbpol.2020.117484_bib0295","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1159\/000276996","article-title":"Molecular-weight-dependent toxic effects of chitosans on the human keratinocyte cell line HaCaT","volume":"23","author":"Wiegand","year":"2010","journal-title":"Skin Pharmacology and Physiology"},{"issue":"6","key":"10.1016\/j.carbpol.2020.117484_bib0300","article-title":"A review on antibiotic resistance: Alarm bells are ringing","volume":"9","author":"Zaman","year":"2017","journal-title":"Cureus"}],"container-title":["Carbohydrate Polymers"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S014486172031657X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S014486172031657X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T18:35:41Z","timestamp":1777487741000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S014486172031657X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3]]},"references-count":60,"alternative-id":["S014486172031657X"],"URL":"https:\/\/doi.org\/10.1016\/j.carbpol.2020.117484","relation":{},"ISSN":["0144-8617"],"issn-type":[{"value":"0144-8617","type":"print"}],"subject":[],"published":{"date-parts":[[2021,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Wound dressing of chitosan-based-crosslinked gelatin\/ polyvinyl pyrrolidone embedded silver nanoparticles, for targeting multidrug resistance microbes","name":"articletitle","label":"Article Title"},{"value":"Carbohydrate Polymers","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.carbpol.2020.117484","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"117484"}}