{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T17:54:32Z","timestamp":1782496472519,"version":"3.54.5"},"reference-count":77,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100004457","name":"The World Academy of Sciences","doi-asserted-by":"publisher","award":["3240299288"],"award-info":[{"award-number":["3240299288"]}],"id":[{"id":"10.13039\/100004457","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["3240299288"],"award-info":[{"award-number":["3240299288"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["3240299288"],"award-info":[{"award-number":["3240299288"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Carbohydrate Polymers"],"published-print":{"date-parts":[[2021,3]]},"DOI":"10.1016\/j.carbpol.2020.117492","type":"journal-article","created":{"date-parts":[[2020,12,19]],"date-time":"2020-12-19T01:59:37Z","timestamp":1608343177000},"page":"117492","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":15,"special_numbering":"C","title":["Biodegradable nanoparticles from prosopisylated cellulose as a platform for enhanced oral bioavailability of poorly water-soluble drugs"],"prefix":"10.1016","volume":"256","author":[{"given":"Franklin Chimaobi","family":"Kenechukwu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcos Lopes","family":"Dias","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eduardo","family":"Ricci-J\u00fanior","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.carbpol.2020.117492_bib0005","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1111\/j.1365-2621.2004.00801.x","article-title":"The chemical composition and some physical properties of a water-soluble gum from Prosopis africana seeds","volume":"39","author":"Achi","year":"2004","journal-title":"International Journal of Food Science & Technology"},{"key":"10.1016\/j.carbpol.2020.117492_bib0010","first-page":"34","article-title":"Evaluation of the physicochemical properties of a new polysaccharide gum from Prosopis africana","volume":"1","author":"Adikwu","year":"2001","journal-title":"Journal of Pharmaceutical and Allied Sciences"},{"issue":"5","key":"10.1016\/j.carbpol.2020.117492_bib0015","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1248\/bpb.26.662","article-title":"Bioadhesive delivery of metformin using prosopis gum with antidiabetic potential","volume":"26","author":"Adikwu","year":"2003","journal-title":"Biological and Pharmaceutical Bulletin"},{"key":"10.1016\/j.carbpol.2020.117492_bib0020","doi-asserted-by":"crossref","first-page":"S34","DOI":"10.1663\/0013-0001(2004)58[S34:PAMSRA]2.0.CO;2","article-title":"Prosopis africana (mimosaceae): Stem, root and seeds in the economy of the savanna areas of Nigeria","volume":"58","author":"Agboola","year":"2004","journal-title":"Economic Botanicals"},{"issue":"1983","key":"10.1016\/j.carbpol.2020.117492_bib0025","first-page":"1","article-title":"Dermatopharmacokinetic and pharmacodynamic evaluation of ethosomes of griseofulvin designed for dermal delivery","volume":"15","author":"Aggarwal","year":"2013","journal-title":"Journal of Nanoparticle Research."},{"key":"10.1016\/j.carbpol.2020.117492_bib0030","first-page":"1","article-title":"The PAS stain for routine diagnosis of onychomycosis","volume":"31","author":"Alkhayat","year":"2009","journal-title":"Bahrain Medical Bulletin"},{"key":"10.1016\/j.carbpol.2020.117492_bib0035","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1023\/A:1016212804288","article-title":"A theoretical basis for a biopharmaceutical drug classification: The correlation of in vitro drug product dissolution and in vivo bioavailability","volume":"12","author":"Amidon","year":"1995","journal-title":"Pharmaceutical Research"},{"issue":"2","key":"10.1016\/j.carbpol.2020.117492_bib0040","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1366\/10-06024","article-title":"Spectroscopic and x-ray diffraction study of structural disorder in cryomilled and amorphous griseofulvin","volume":"65","author":"Anna","year":"2011","journal-title":"Appled Spectroscopy"},{"issue":"4","key":"10.1016\/j.carbpol.2020.117492_bib0045","first-page":"743","article-title":"A new lipid based drug delivery system (LBDDS) for oral delivery of tioconazole","volume":"3","author":"Attama","year":"2011","journal-title":"International Journal of Drug Delivery Technology"},{"issue":"3","key":"10.1016\/j.carbpol.2020.117492_bib0050","doi-asserted-by":"crossref","first-page":"296","DOI":"10.3109\/13880200903121006","article-title":"Analgesic and anti-inflammatory effects of methanol stem bark extract of Prosopis africana","volume":"48","author":"Ayanwuyi","year":"2010","journal-title":"Pharmaceutical Biological"},{"issue":"5","key":"10.1016\/j.carbpol.2020.117492_bib0055","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1590\/S0103-50532006000500005","article-title":"Characterization of Prosopis juliflora seed gum and the effect of its addition on k-carrageenan systems","volume":"17","author":"Azero","year":"2006","journal-title":"Journal of Brazilian Chemical Society"},{"key":"10.1016\/j.carbpol.2020.117492_bib0060","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1099\/jmm.0.46542-0","article-title":"Evaluation of susceptibility of Trichophyton mentagrophytes and Trichophyton rubrum clinical isolates to antifungal drugs using a modified CLSI microdilution method (M38-A)","volume":"56","author":"Barros","year":"2007","journal-title":"Journal of Medical Microbiology"},{"issue":"3","key":"10.1016\/j.carbpol.2020.117492_bib0065","doi-asserted-by":"crossref","first-page":"91","DOI":"10.4103\/2231-4040.184591","article-title":"Preparation and physicochemical characterization of topical chitosan-based film containing griseofulvin-loaded liposomes","volume":"7","author":"Bavarsad","year":"2016","journal-title":"Journal of Advanced Pharmaceutical Technology and Research"},{"key":"10.1016\/j.carbpol.2020.117492_bib0070","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1038\/nbt.3330","article-title":"Principles of nanoparticle design for overcoming biological barriers to drug delivery","volume":"33","author":"Blanco","year":"2015","journal-title":"Natural Biotechnology"},{"key":"10.1016\/j.carbpol.2020.117492_bib0075","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.ejpb.2008.12.011","article-title":"Preparation and characterization of mucinated cellulose microparticles for therapeutic and drug delivery purposes","volume":"72","author":"Builders","year":"2009","journal-title":"European Journal of Pharmaceutics and Biopharmaceutics"},{"key":"10.1016\/j.carbpol.2020.117492_bib0080","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.ijpharm.2009.12.056","article-title":"Novel multifunctional pharmaceutical excipients derived from microcrystalline cellulose\u2013starch microparticulate composites prepared by compatibilized reactive polymer blending","volume":"388","author":"Builders","year":"2010","journal-title":"International Journal of Pharmaceutics"},{"issue":"3","key":"10.1016\/j.carbpol.2020.117492_bib0085","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1016\/j.ejpb.2008.06.021","article-title":"Preparation and evaluation of mucinated sodium alginate microparticles for oral insulin delivery","volume":"70","author":"Builders","year":"2018","journal-title":"European Journal of Pharmaceutics and Biopharmaceutics"},{"issue":"4","key":"10.1016\/j.carbpol.2020.117492_bib0090","article-title":"The rabbit as an animal model for experimental surgery","volume":"24","author":"Calasans-Maia","year":"2009","journal-title":"Acta Circular Brasiliero"},{"key":"10.1016\/j.carbpol.2020.117492_bib0095","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/j.carbpol.2010.07.036","article-title":"Structural and thermal characterization of galactomannans from non-conventional sources","volume":"83","author":"Cerqueira","year":"2011","journal-title":"Carbohydrate Polymers"},{"key":"10.1016\/j.carbpol.2020.117492_bib0100","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1002\/jcla.21973","article-title":"Causative agents of onychomycosis: A 7 year study","volume":"30","author":"Chadeganipour","year":"2016","journal-title":"Journal of Clinical and Laboratory Analysis"},{"key":"10.1016\/j.carbpol.2020.117492_bib0105","doi-asserted-by":"crossref","first-page":"1669","DOI":"10.1007\/s00217-008-0892-0","article-title":"Physico-chemical and functional characterization of the galactomannan obtained from mesquite seeds (Prosopis pallida)","volume":"227","author":"Chaires-Mart\u00ednez","year":"2008","journal-title":"European Food Research and Technology"},{"key":"10.1016\/j.carbpol.2020.117492_bib0110","doi-asserted-by":"crossref","first-page":"1505","DOI":"10.1002\/jps.2600581218","article-title":"Preparation and dissolution characteristics of several fast-release solid dispersions of griseofulvin","volume":"58","author":"Chiou","year":"1969","journal-title":"Journal of Pharmaceutical Sciences"},{"key":"10.1016\/j.carbpol.2020.117492_bib0115","series-title":"Production and characterization of Prosopis galactomannan","author":"Cruz-Alcedo","year":"1999"},{"key":"10.1016\/j.carbpol.2020.117492_bib0120","first-page":"180","article-title":"Enhancement of solubility and dissolution property of griseofulvin by nanocrystallization","volume":"3","author":"Dandagi","year":"2011","journal-title":"International Journal of Drug Development Research."},{"key":"10.1016\/j.carbpol.2020.117492_bib0125","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1016\/j.eurpolymj.2014.12.019","article-title":"Reactive compatibilization of polyamide6\/polyethylene non-woven based thermoplastic composites","volume":"63","author":"Dasdemir","year":"2015","journal-title":"European Polymer Journal"},{"key":"10.1016\/j.carbpol.2020.117492_bib0130","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.exer.2015.05.003","article-title":"Rabbit as an animal model for intravitreal pharmacokinetics: Clinical predictability and quality of published data","volume":"137","author":"del Amo","year":"2015","journal-title":"Experimental Eye Research"},{"key":"10.1016\/j.carbpol.2020.117492_bib0135","doi-asserted-by":"crossref","first-page":"583","DOI":"10.3109\/03639049809085663","article-title":"Enhancement of bioavailability of griseofulvin by its complexation with \u03b2-cyclodextrin","volume":"24","author":"Dhanaraju","year":"2008","journal-title":"Drug Development and Industrial Pharmacy."},{"key":"10.1016\/j.carbpol.2020.117492_bib0140","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.jconrel.2014.11.017","article-title":"Development of topical therapeutics for management of onychomycosis and other nail disorders: A pharmaceutical perspective","volume":"199","author":"Elsayed","year":"2015","journal-title":"Journal of Controlled Release"},{"key":"10.1016\/j.carbpol.2020.117492_bib0145","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.ijpharm.2007.10.008","article-title":"Evaluation of in vivo dissolution behavior and GI transit of griseofulvin, a BCS class II drug","volume":"352","author":"Fujioka","year":"2008","journal-title":"International Journal of Pharmaceutics"},{"key":"10.1016\/j.carbpol.2020.117492_bib0150","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/j.ijpharm.2012.08.015","article-title":"Preparation and evaluation of antifungal efficacy of griseofulvin-loaded deformable membrane vesicles in optimized guinea pig model of Microsporum canis \u2013 Dermatophytosis","volume":"437","author":"Goindi","year":"2012","journal-title":"International Journal of Pharmaceutics"},{"key":"10.1016\/j.carbpol.2020.117492_bib0155","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/j.det.2006.03.010","article-title":"Therapies for onychomycosis: A review","volume":"24","author":"Gupta","year":"2006","journal-title":"Dermatology and Clinical"},{"issue":"6","key":"10.1016\/j.carbpol.2020.117492_bib0160","first-page":"646","article-title":"The influence of formulation on the absorption of orally administered griseofulvin preparations in rabbits","volume":"42","author":"Hansford","year":"1980","journal-title":"Drug Development and Industrial Pharmacy."},{"issue":"1","key":"10.1016\/j.carbpol.2020.117492_bib0165","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1021\/bm0495349","article-title":"Structural aspects in semicrystalline samples of the mannan II family","volume":"6","author":"Heux","year":"2005","journal-title":"Biomacromolecules"},{"issue":"4","key":"10.1016\/j.carbpol.2020.117492_bib0170","first-page":"1186","article-title":"Enhanced oral bioavailability of griseofulvin via niosomes","volume":"10","author":"Jadon","year":"2009","journal-title":"Association of American Pharmaceutical Scientists Pharmaceutical Science and Technology."},{"key":"10.1016\/j.carbpol.2020.117492_bib0175","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1007\/s11046-009-9212-x","article-title":"Candidal onychomycosis: A mini-review","volume":"168","author":"Jayatilake","year":"2009","journal-title":"Mycopathologia"},{"key":"10.1016\/j.carbpol.2020.117492_bib0180","first-page":"123","article-title":"Physical properties of griseofulvin-phospholipid mixture, and relationship between surface tension and nanoparticles during freeze-drying","volume":"5","author":"Kamiya","year":"2010","journal-title":"Asian Journal of Pharmaceutical Sciences"},{"key":"10.1016\/j.carbpol.2020.117492_bib0185","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1080\/00021369.1973.10860687","article-title":"Infrared spectroscopy of some mannans","volume":"37","author":"Kato","year":"1973","journal-title":"Agricultural and Biological Chemistry"},{"key":"10.1016\/j.carbpol.2020.117492_bib0190","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1016\/j.ejps.2017.10.002","article-title":"Surface-modified mucoadhesive microgels as a controlled release system for miconazole nitrate to improve localized treatment of vulvovaginal candidiasis","volume":"111","author":"Kenechukwu","year":"2018","journal-title":"European Journal of Pharmaceutical Sciences"},{"key":"10.1016\/j.carbpol.2020.117492_bib0195","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/S0378-5173(96)04827-2","article-title":"Use of bioadhesive polymer to improve the bioavailability of griseofulvin","volume":"148","author":"Khalid","year":"1997","journal-title":"International Journal of Pharmaceutics."},{"key":"10.1016\/j.carbpol.2020.117492_bib0200","first-page":"90","article-title":"Phytochemical composition and antimicrobial Prosopis africana against some selected oral pathogens","volume":"5","author":"Kolapo","year":"2009","journal-title":"World Journal of Agricultural Sciences"},{"key":"10.1016\/j.carbpol.2020.117492_bib0205","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.carbpol.2015.02.042","article-title":"Physicochemical characterization of the polysaccharide from Bletilla striata: Effect of drying method","volume":"125","author":"Kong","year":"2015","journal-title":"Carbohydrate Polymers"},{"key":"10.1016\/j.carbpol.2020.117492_bib0210","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1002\/pat.3458","article-title":"Reactive blending of PE-GMA\/PA6: Effect of composition and processing conditions","volume":"26","author":"Kossentini-Kallel","year":"2015","journal-title":"Polymer Advances and Technology"},{"key":"10.1016\/j.carbpol.2020.117492_bib0215","doi-asserted-by":"crossref","DOI":"10.1016\/j.jddst.2019.101221","article-title":"Nanotechnology based approaches to enhance aqueous solubility and bioavailability of griseofulvin: A literature survey","volume":"53","author":"Kumar","year":"2019","journal-title":"Journal of Drug Delivery Science and Technology"},{"key":"10.1016\/j.carbpol.2020.117492_bib0220","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1002\/pat.595","article-title":"Investigation of solubility of MCC in aqueous NaOH","volume":"16","author":"Kuo","year":"2005","journal-title":"Polymer Advances and Technology"},{"key":"10.1016\/j.carbpol.2020.117492_bib0225","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1016\/j.ajps.2014.09.002","article-title":"Effect of formulation variables on in vitro release of a water-soluble drug from chitosan-sodium alginate matrix tablets","volume":"10","author":"Li","year":"2015","journal-title":"Asian Journal of Pharmaceutical Sciences"},{"key":"10.1016\/j.carbpol.2020.117492_bib0230","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.jconrel.2016.04.012","article-title":"Dual chitosan\/albumin-coated alginate\/ dextran sulfate nanoparticles for enhanced oral delivery of insulin","volume":"23","author":"Lopes","year":"2016","journal-title":"Journal of Controlled Release"},{"key":"10.1016\/j.carbpol.2020.117492_bib0235","doi-asserted-by":"crossref","first-page":"1042","DOI":"10.2174\/1389200214666131118234935","article-title":"Enrofloxacin: Pharmacokinetics and metabolism in domestic animal species","volume":"14","author":"Lopez-Cadenas","year":"2013","journal-title":"Current Drug Metabolism"},{"issue":"2","key":"10.1016\/j.carbpol.2020.117492_bib0240","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1016\/j.foodhyd.2012.08.012","article-title":"Physicochemical characterization and functional properties of galactomannans from mesquite seeds (Prosopis spp.)","volume":"30","author":"Lopez-Franco","year":"2013","journal-title":"Food Hydrocolloids"},{"key":"10.1016\/j.carbpol.2020.117492_bib0245","article-title":"Development of ethosomal vesicular carrier for topical application of griseofulvin: Effect of ethanol concentration","author":"Mbah","year":"2017","journal-title":"Journal of Pharmaceutical Investigation"},{"issue":"115506","key":"10.1016\/j.carbpol.2020.117492_bib0250","first-page":"1","article-title":"Insulin-loaded mucoadhesive nanoparticles based on mucin-chitosan complexes for oral delivery and diabetes treatment","volume":"229","author":"Momoh","year":"2020","journal-title":"Carbohydrate Polymers"},{"key":"10.1016\/j.carbpol.2020.117492_bib0255","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/j.msec.2018.12.041","article-title":"A new lipid-based oral delivery system of erythromycin for prolong sustain release activity","volume":"97","author":"Momoh","year":"2019","journal-title":"Material Science & Engineering C"},{"key":"10.1016\/j.carbpol.2020.117492_bib0260","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.foodhyd.2009.07.001","article-title":"Modifications in stability and structure of whey protein-coated o\/w emulsions by interacting chitosan and gum arabic mixed dispersions","volume":"224","author":"Moschakis","year":"2010","journal-title":"Food Hydrocolloids"},{"key":"10.1016\/j.carbpol.2020.117492_bib0265","first-page":"2191","article-title":"Parameters and characteristics governing cellular internalization and trans-barrier trafficking of nanostructures","volume":"10","author":"Murugan","year":"2015","journal-title":"International Journal of Nanomedicine"},{"issue":"3","key":"10.1016\/j.carbpol.2020.117492_bib0270","first-page":"716","article-title":"Evaluation of Prospis africana seed gum as an extended release polymer for tablet formulation","volume":"16","author":"Nadaf","year":"2015","journal-title":"American Association of Pharmaceutical Scientists Pharmaceutical Science and Technology"},{"key":"10.1016\/j.carbpol.2020.117492_bib0275","doi-asserted-by":"crossref","first-page":"012007","DOI":"10.1088\/1757-899X\/180\/1\/012007","article-title":"Preparation and characterization of cellulose microcrystalline (MCC) from fiber of empty fruit bunch palm oil. 1st annual applied science and engineering Conference","volume":"180","author":"Nasution","year":"2017","journal-title":"IOP Conference Series: Materials Science and Engineering"},{"issue":"3","key":"10.1016\/j.carbpol.2020.117492_bib0280","first-page":"167","article-title":"Sustained release mebendazole microcapsules prepared with Prosopis africana peel powder (PAPP) hydrogel","volume":"9","author":"Nnamani","year":"2017","journal-title":"Indian Journal of Novel Drug Delivery"},{"key":"10.1016\/j.carbpol.2020.117492_bib0285","unstructured":"Nnamani, P.O., Lokhande, C.D., Shinde, A.J., Jadhav, N.R., Sanandam, M.R. (2014). Solid oral pharmaceutical composition, Nigerian patent 565, September 30."},{"key":"10.1016\/j.carbpol.2020.117492_bib0290","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.foodhyd.2015.11.034","article-title":"Solution characteristics and thermo-rheology of Prosopis africana seed polysaccharide","volume":"56","author":"Nwokocha","year":"2016","journal-title":"Food Hydrocolloids"},{"key":"10.1016\/j.carbpol.2020.117492_bib0295","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1080\/03639040802244292","article-title":"The use of liquid self-microemulsifying drug delivery systems based on peanut oil\/tween 80 in the delivery of griseofulvin","volume":"35","author":"Ofokansi","year":"2009","journal-title":"Drug Development and Industrial Pharmacy"},{"issue":"25","key":"10.1016\/j.carbpol.2020.117492_bib0300","first-page":"1","article-title":"Influence of the encapsulation efficiency and size of liposomes on the oral bioavailability of griseofulvin-loaded liposomes","volume":"8","author":"Ong","year":"2016","journal-title":"Pharmaceutics."},{"key":"10.1016\/j.carbpol.2020.117492_bib0305","first-page":"3867","article-title":"Comparative crystal structure determination of griseofulvin: Powder x-ray diffraction versus single-crystal x-ray diffraction","volume":"57","author":"Pan","year":"2012","journal-title":"Chinese Scientific Bulletin"},{"key":"10.1016\/j.carbpol.2020.117492_bib0310","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1002\/masy.200551108","article-title":"Morphology and structure of crystalline polysaccharides: Some recent studies","volume":"229","author":"Putaux","year":"2005","journal-title":"Macromolecles Symposium"},{"issue":"3","key":"10.1016\/j.carbpol.2020.117492_bib0315","first-page":"176","article-title":"Do blood sampling sites affect pharmacokinetics?","volume":"4","author":"Rangaraj","year":"2014","journal-title":"Chemistry & Biology Interface"},{"key":"10.1016\/j.carbpol.2020.117492_bib0320","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/j.ejpb.2012.09.012","article-title":"Solid crystal suspensions containing griseofulvin\u2013preparation and bioavailability testing","volume":"83","author":"Reitz","year":"2013","journal-title":"European Journal of Pharmaceutics and Biopharmaceutics"},{"key":"10.1016\/j.carbpol.2020.117492_bib0325","series-title":"Hand book of pharmaceutical excipients","first-page":"120","author":"Rowe","year":"2003"},{"issue":"2","key":"10.1016\/j.carbpol.2020.117492_bib0330","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1080\/00222340500523842","article-title":"Thermal behavior of poly(ethylene terephthalate) crystalline and amorphous phases by wide angle x\u2010ray scattering","volume":"45","author":"Sirelli","year":"2006","journal-title":"Journal of Macromolecular Science, Part B: Physics"},{"key":"10.1016\/j.carbpol.2020.117492_bib0335","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1016\/j.carbpol.2013.06.072","article-title":"Rapid synthesis of graft copolymers from natural cellulose fibers","volume":"98","author":"Thakur","year":"2013","journal-title":"Carbohydrate Polymers"},{"key":"10.1016\/j.carbpol.2020.117492_bib0340","first-page":"423","article-title":"Griseofulvin nanosuspensions from triacetin-in-water emulsions","volume":"13","author":"Trona","year":"2003","journal-title":"STP Pharmaceutical Science"},{"key":"10.1016\/j.carbpol.2020.117492_bib0345","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/S0378-5173(03)00029-2","article-title":"Preparation of griseofulvin nanoparticles from water-dilutable microemulsions","volume":"254","author":"Trotta","year":"2003","journal-title":"International Journal of Pharmaceutics"},{"key":"10.1016\/j.carbpol.2020.117492_bib0350","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.carbpol.2016.01.020","article-title":"Microcrystalline-cellulose and polypropylene based composite: A simple, selective and effective material for microwavable packaging","volume":"142","author":"Ummartyotin","year":"2016","journal-title":"Carbohydrate Polymers"},{"key":"10.1016\/j.carbpol.2020.117492_bib0355","series-title":"United States pharmacopoeial convention","author":"United States Pharmacopoeia XXIII","year":"1995"},{"key":"10.1016\/j.carbpol.2020.117492_bib0360","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.carbpol.2008.09.028","article-title":"Physicochemical and mechanical characterization of galactomannan from Mimosa scabrella: Effect of drying method","volume":"76","author":"Vendruscolo","year":"2009","journal-title":"Carbohydrate Polymers"},{"key":"10.1016\/j.carbpol.2020.117492_bib0365","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.fitote.2013.10.008","article-title":"A new gluco-mannan from Bletilla striata: Structural and anti-fibrosis effects","volume":"92","author":"Wang","year":"2014","journal-title":"Fitoterapia"},{"key":"10.1016\/j.carbpol.2020.117492_bib0370","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1016\/S0927-7757(99)00290-3","article-title":"Electro-kinetic surface characterization of biomedical polymers\u2014A survey","volume":"159","author":"Werner","year":"1999","journal-title":"Colloids and Surfaces A.: Physicochemical Aspects"},{"key":"10.1016\/j.carbpol.2020.117492_bib0375","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/0378-5173(96)04669-8","article-title":"An investigation into the critical surfactant concentration for solid solubility of hydrophobic drug in different polyethylene glycols","volume":"142","author":"Wulff","year":"1996","journal-title":"International Journal of Pharmaceutics"},{"key":"10.1016\/j.carbpol.2020.117492_bib0380","doi-asserted-by":"crossref","first-page":"14221","DOI":"10.1074\/jbc.M113.465609","article-title":"Role of replication protein A in double holliday junction dissolution mediated by the BLM-Topo III\u03b1-RMI1-RMI2 protein complex","volume":"288","author":"Xue","year":"2013","journal-title":"Journal of Biology and Chemistry"},{"key":"10.1016\/j.carbpol.2020.117492_bib0385","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/j.ijpharm.2005.01.020","article-title":"Preparation and characterization of poly-e-caprolactone nanoparticles containing griseofulvin","volume":"29","author":"Zili","year":"2005","journal-title":"International Journal of Pharmaceutics"}],"container-title":["Carbohydrate Polymers"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0144861720316659?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0144861720316659?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T00:06:37Z","timestamp":1758931597000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0144861720316659"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3]]},"references-count":77,"alternative-id":["S0144861720316659"],"URL":"https:\/\/doi.org\/10.1016\/j.carbpol.2020.117492","relation":{},"ISSN":["0144-8617"],"issn-type":[{"value":"0144-8617","type":"print"}],"subject":[],"published":{"date-parts":[[2021,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Biodegradable nanoparticles from prosopisylated cellulose as a platform for enhanced oral bioavailability of poorly water-soluble drugs","name":"articletitle","label":"Article Title"},{"value":"Carbohydrate Polymers","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.carbpol.2020.117492","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"117492"}}