{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T12:42:06Z","timestamp":1784724126563,"version":"3.55.0"},"reference-count":75,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,6,25]],"date-time":"2023-06-25T00:00:00Z","timestamp":1687651200000},"content-version":"am","delay-in-days":267,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Carbohydrate Polymers"],"published-print":{"date-parts":[[2022,10]]},"DOI":"10.1016\/j.carbpol.2022.119734","type":"journal-article","created":{"date-parts":[[2022,6,18]],"date-time":"2022-06-18T10:58:44Z","timestamp":1655549924000},"page":"119734","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"special_numbering":"C","title":["Binding of heparan sulfate to human cystatin C modulates inhibition of cathepsin L: Putative consequences in mucopolysaccharidosis"],"prefix":"10.1016","volume":"293","author":[{"given":"Sophie","family":"Denamur","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thibault","family":"Chazeirat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martyna","family":"Maszota-Zieleniak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Romain R.","family":"Viv\u00e8s","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahlame","family":"Saidi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fuming","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert J.","family":"Linhardt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fran\u00e7ois","family":"Labarthe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sergey A.","family":"Samsonov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gilles","family":"Lalmanach","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabien","family":"Lecaille","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.carbpol.2022.119734_bb0005","doi-asserted-by":"crossref","first-page":"18167","DOI":"10.1074\/jbc.M801327200","article-title":"Cathepsin L is responsible for processing and activation of proheparanase through multiple cleavages of a linker segment","volume":"283","author":"Abboud-Jarrous","year":"2008","journal-title":"The Journal of Biological Chemistry"},{"key":"10.1016\/j.carbpol.2022.119734_bb0010","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1016\/0076-6879(94)44051-4","article-title":"Cystatins","volume":"244","author":"Abrahamson","year":"1994","journal-title":"Methods in Enzymology"},{"key":"10.1016\/j.carbpol.2022.119734_bb0015","first-page":"179","article-title":"Cystatins","author":"Abrahamson","year":"2003","journal-title":"Biochemical Society"},{"key":"10.1016\/j.carbpol.2022.119734_bb0020","doi-asserted-by":"crossref","first-page":"11282","DOI":"10.1016\/S0021-9258(18)67380-6","article-title":"Isolation of six cysteine proteinase inhibitors from human urine. Their physicochemical and enzyme kinetic properties and concentrations in biological fluids","volume":"261","author":"Abrahamson","year":"1986","journal-title":"The Journal of Biological Chemistry"},{"key":"10.1016\/j.carbpol.2022.119734_bb0025","doi-asserted-by":"crossref","first-page":"9688","DOI":"10.1016\/S0021-9258(18)47989-6","article-title":"Identification of the probable inhibitory reactive sites of the cysteine proteinase inhibitors human cystatin C and chicken cystatin","volume":"262","author":"Abrahamson","year":"1987","journal-title":"The Journal of Biological Chemistry"},{"key":"10.1016\/j.carbpol.2022.119734_bb0030","doi-asserted-by":"crossref","first-page":"E4215","DOI":"10.3390\/molecules25184215","article-title":"Heparan sulfate proteoglycans biosynthesis and post synthesis mechanisms combine few enzymes and few Core proteins to generate extensive structural and functional diversity","volume":"25","author":"Annaval","year":"2020","journal-title":"Molecules"},{"key":"10.1016\/j.carbpol.2022.119734_bb0035","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1042\/bj2010189","article-title":"L-trans-epoxysuccinyl-leucylamido(4-guanidino)butane (E-64) and its analogues as inhibitors of cysteine proteinases including cathepsins BH and L","volume":"201","author":"Barrett","year":"1982","journal-title":"Biochem. J"},{"key":"10.1016\/j.carbpol.2022.119734_bb0040","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1007\/s10545-012-9555-1","article-title":"Respiratory and sleep disorders in mucopolysaccharidosis","volume":"36","author":"Berger","year":"2013","journal-title":"Journal of Inherited Metabolic Disease"},{"issue":"Suppl","key":"10.1016\/j.carbpol.2022.119734_bb0045","first-page":"183","article-title":"Pathophysiological interpretation of kinetic constants of protease inhibitors","volume":"16","author":"Bieth","year":"1980","journal-title":"Bulletin Europ\u00e9en de Physiopathologie Respiratoire"},{"key":"10.1016\/j.carbpol.2022.119734_bb0050","doi-asserted-by":"crossref","DOI":"10.1016\/j.jmgm.2022.108153","article-title":"In silico and in vitro mapping of specificity patterns of glycosaminoglycans towards cysteine cathepsins B, L, K, S and V","volume":"113","author":"Bojarski","year":"2022","journal-title":"Journal of Molecular Graphics & Modelling"},{"key":"10.1016\/j.carbpol.2022.119734_bb0055","first-page":"589","article-title":"Cystatin C, alias post-gamma-globulin: A marker for multiple sclerosis?","volume":"25","author":"Bollengier","year":"1987","journal-title":"Journal of Clinical Chemistry and Clinical Biochemistry"},{"key":"10.1016\/j.carbpol.2022.119734_bb0060","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1183\/09031936.04.00105304","article-title":"Lysosomal cysteine proteases in the lung: Role in protein processing and immunoregulation","volume":"23","author":"B\u00fchling","year":"2004","journal-title":"The European Respiratory Journal"},{"key":"10.1016\/j.carbpol.2022.119734_bb0065","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1046\/j.1471-4159.2001.00256.x","article-title":"Distinct properties of wild-type and the amyloidogenic human cystatin C variant of hereditary cerebral hemorrhage with amyloidosis, icelandic type","volume":"77","author":"Calero","year":"2001","journal-title":"Journal of Neurochemistry"},{"key":"10.1016\/j.carbpol.2022.119734_bb0070","series-title":"AMBER 2017","author":"Case","year":"2017"},{"key":"10.1016\/j.carbpol.2022.119734_bb0075","doi-asserted-by":"crossref","DOI":"10.1016\/j.carbpol.2020.117261","article-title":"The abnormal accumulation of heparan sulfate in patients with mucopolysaccharidosis prevents the elastolytic activity of cathepsin V","volume":"253","author":"Chazeirat","year":"2021","journal-title":"Carbohydrate Polymers"},{"key":"10.1016\/j.carbpol.2022.119734_bb0080","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.cccn.2003.11.011","article-title":"Increased cystatin C serum concentrations in patients with hepatic diseases of various severities","volume":"341","author":"Chu","year":"2004","journal-title":"Clinica Chimica Acta"},{"key":"10.1016\/j.carbpol.2022.119734_bb0085","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/j.ymgme.2006.08.001","article-title":"Effect of neonatal administration of a retroviral vector expressing \u03b1-l-iduronidase upon lysosomal storage in brain and other organs in mucopolysaccharidosis I mice","volume":"90","author":"Chung","year":"2007","journal-title":"Molecular Genetics and Metabolism"},{"key":"10.1016\/j.carbpol.2022.119734_bb0090","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1016\/j.oraloncology.2006.08.009","article-title":"The upregulation of cystatin C in oral submucous fibrosis","volume":"43","author":"Chung-Hung","year":"2007","journal-title":"Oral Oncology"},{"key":"10.1016\/j.carbpol.2022.119734_bb0095","doi-asserted-by":"crossref","first-page":"167","DOI":"10.3109\/14756369909036552","article-title":"Interaction of cystatin C variants with papain and human cathepsins B, H and L","volume":"14","author":"Cimerman","year":"1999","journal-title":"Journal of Enzyme Inhibition"},{"key":"10.1016\/j.carbpol.2022.119734_bb0100","doi-asserted-by":"crossref","first-page":"E979","DOI":"10.3390\/cells9040979","article-title":"Cathepsins in the pathophysiology of mucopolysaccharidoses: New perspectives for therapy","volume":"9","author":"De Pasquale","year":"2020","journal-title":"Cells"},{"key":"10.1016\/j.carbpol.2022.119734_bb0105","doi-asserted-by":"crossref","first-page":"00567","DOI":"10.1183\/23120541.00567-2021","article-title":"Recommended respiratory tests are not routinely performed for mucopolysaccharidosis patients","volume":"8","author":"Denamur","year":"2022","journal-title":"ERJ Open Research"},{"key":"10.1016\/j.carbpol.2022.119734_bb0110","first-page":"312","article-title":"The dependence of chemokine-glycosaminoglycan interactions on chemokine oligomerization","volume":"26","author":"Dyer","year":"2016","journal-title":"Glycobiology"},{"key":"10.1016\/j.carbpol.2022.119734_bb0115","series-title":"A density-based algorithm for discovering clusters in large spatial databases with noise","first-page":"226","author":"Ester","year":"1996"},{"key":"10.1016\/j.carbpol.2022.119734_bb0120","doi-asserted-by":"crossref","first-page":"65","DOI":"10.3109\/00365511003642535","article-title":"Non-invasive estimation of glomerular filtration rate (GFR). The Lund model: Simultaneous use of cystatin C- and creatinine-based GFR-prediction equations, clinical data and an internal quality check","volume":"70","author":"Grubb","year":"2010","journal-title":"Scandinavian Journal of Clinical and Laboratory Investigation"},{"key":"10.1016\/j.carbpol.2022.119734_bb0125","first-page":"1","article-title":"Fatal and unanticipated cardiorespiratory disease in a two-year-old child with hurler syndrome following successful stem cell transplant","volume":"10","author":"Gupta","year":"2013","journal-title":"JIMD Reports"},{"key":"10.1016\/j.carbpol.2022.119734_bb0130","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1177\/030098589202900203","article-title":"Hepatic storage of glycosaminoglycans in feline and canine models of mucopolysaccharidoses I, VI, and VII","volume":"29","author":"Haskins","year":"1992","journal-title":"Veterinary Pathology"},{"key":"10.1016\/j.carbpol.2022.119734_bb0135","doi-asserted-by":"crossref","first-page":"3722","DOI":"10.1074\/jbc.M109.037358","article-title":"Heparin enhances serpin inhibition of the cysteine protease cathepsin L","volume":"285","author":"Higgins","year":"2010","journal-title":"The Journal of Biological Chemistry"},{"key":"10.1016\/j.carbpol.2022.119734_bb0140","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1093\/glycob\/7.2.231","article-title":"Preparation and structure of heparin lyase-derived heparan sulfate oligosaccharides","volume":"7","author":"Hileman","year":"1997","journal-title":"Glycobiology"},{"key":"10.1016\/j.carbpol.2022.119734_bb0145","doi-asserted-by":"crossref","first-page":"392","DOI":"10.3109\/00365513.2014.900186","article-title":"Does the type of creatinine assay affect creatinine clearance determination?","volume":"74","author":"Hoste","year":"2014","journal-title":"Scandinavian Journal of Clinical and Laboratory Investigation"},{"issue":"33\u201338","key":"10.1016\/j.carbpol.2022.119734_bb0150","first-page":"27","article-title":"VMD: Visual molecular dynamics","volume":"14","author":"Humphrey","year":"1996","journal-title":"Journal of Molecular Graphics"},{"key":"10.1016\/j.carbpol.2022.119734_bb0160","doi-asserted-by":"crossref","first-page":"4192","DOI":"10.1002\/1873-3468.12463","article-title":"Human cystatin C monomer, dimer, oligomer, and amyloid structures are related to health and disease","volume":"590","author":"Jurczak","year":"2016","journal-title":"FEBS Letters"},{"key":"10.1016\/j.carbpol.2022.119734_bb0165","doi-asserted-by":"crossref","first-page":"1239","DOI":"10.1002\/jcph.1132","article-title":"Cystatin C is a more reliable biomarker for determining eGFR to support drug development studies","volume":"58","author":"Kar","year":"2018","journal-title":"Journal of Clinical Pharmacology"},{"key":"10.1016\/j.carbpol.2022.119734_bb0170","doi-asserted-by":"crossref","first-page":"16239","DOI":"10.1074\/jbc.M113.542407","article-title":"Regulation of TGF-\u03b21-driven differentiation of human lung fibroblasts: Emerging roles of cathepsin B and cystatin C","volume":"289","author":"Kasabova","year":"2014","journal-title":"The Journal of Biological Chemistry"},{"key":"10.1016\/j.carbpol.2022.119734_bb0175","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1002\/prca.201300047","article-title":"Human cystatin C: A new biomarker of idiopathic pulmonary fibrosis?","volume":"8","author":"Kasabova","year":"2014","journal-title":"Proteomics clinAppl"},{"key":"10.1016\/j.carbpol.2022.119734_bb0180","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1007\/s12018-011-9094-6","article-title":"Cysteine cathepsins: Markers and therapy targets in lung disorders","volume":"9","author":"Kasabova","year":"2011","journal-title":"Clinical Reviews in Bone and Mineral Metabolism"},{"key":"10.1016\/j.carbpol.2022.119734_bb0185","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1186\/s12931-016-0432-6","article-title":"Discordance in cathepsin B and cystatin C expressions in bronchoalveolar fluids between murine bleomycin-induced fibrosis and human idiopathic fibrosis","volume":"17","author":"Kasabova","year":"2016","journal-title":"Respiratory Research"},{"key":"10.1016\/j.carbpol.2022.119734_bb0190","first-page":"622","article-title":"GLYCAM06: A generalizable biomolecular force field","volume":"29","author":"Kirschner","year":"2008","journal-title":"Carbohydrates. Journal of Computational Chemistry"},{"key":"10.1016\/j.carbpol.2022.119734_bb0195","doi-asserted-by":"crossref","first-page":"1726","DOI":"10.1111\/j.1742-4658.2010.07596.x","article-title":"Crystal structure of human cystatin C stabilized against amyloid formation","volume":"277","author":"Kolodziejczyk","year":"2010","journal-title":"The FEBS Journal"},{"key":"10.1016\/j.carbpol.2022.119734_bb0200","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1515\/BC.2006.109","article-title":"Cysteine cathepsins and caspases in silicosis","volume":"387","author":"Lalmanach","year":"2006","journal-title":"Biological Chemistry"},{"key":"10.1016\/j.carbpol.2022.119734_bb0205","doi-asserted-by":"crossref","first-page":"1877","DOI":"10.3390\/cancers13081877","article-title":"Cystatin M\/E (Cystatin 6): A janus-faced cysteine protease inhibitor with both tumor-suppressing and tumor-promoting functions","volume":"13","author":"Lalmanach","year":"2021","journal-title":"Cancers (Basel)"},{"key":"10.1016\/j.carbpol.2022.119734_bb0210","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1515\/hsz-2014-0210","article-title":"Cysteine cathepsins and cystatins: From ancillary tasks to prominent status in lung diseases","volume":"396","author":"Lalmanach","year":"2015","journal-title":"Biological Chemistry"},{"key":"10.1016\/j.carbpol.2022.119734_bb0215","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/j.biochi.2007.08.011","article-title":"Biochemical properties and regulation of cathepsin K activity","volume":"90","author":"Lecaille","year":"2008","journal-title":"Biochimie"},{"key":"10.1016\/j.carbpol.2022.119734_bb0220","doi-asserted-by":"crossref","first-page":"4459","DOI":"10.1021\/cr0101656","article-title":"Human and parasitic papain-like cysteine proteases: Their role in physiology and pathology and recent developments in inhibitor design","volume":"102","author":"Lecaille","year":"2002","journal-title":"Chemical Reviews"},{"key":"10.1016\/j.carbpol.2022.119734_bb0225","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1021\/bi992251u","article-title":"Collagenolytic activity of cathepsin K is specifically modulated by cartilage-resident chondroitin sulfates","volume":"39","author":"Li","year":"2000","journal-title":"Biochemistry"},{"key":"10.1016\/j.carbpol.2022.119734_bb0230","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/0014-5793(89)80135-8","article-title":"Mechanism of inhibition of papain by chicken egg white cystatin. Inhibition constants of N-terminally truncated forms and cyanogen bromide fragments of the inhibitor","volume":"243","author":"Machleidt","year":"1989","journal-title":"FEBS Letters"},{"key":"10.1016\/j.carbpol.2022.119734_bb0235","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1042\/bj3300833","article-title":"Amino acid substitutions in the N-terminal segment of cystatin C create selective protein inhibitors of lysosomal cysteine proteinases","volume":"330","author":"Mason","year":"1998","journal-title":"Biochemical Journal"},{"key":"10.1016\/j.carbpol.2022.119734_bb0240","doi-asserted-by":"crossref","DOI":"10.1016\/j.mbplus.2021.100080","article-title":"The potential role of glycosaminoglycans in serum amyloid a fibril formation by in silico approaches","volume":"12","author":"Maszota-Zieleniak","year":"2021","journal-title":"Matrix Biol Plus"},{"key":"10.1016\/j.carbpol.2022.119734_bb0245","doi-asserted-by":"crossref","first-page":"1639","DOI":"10.1002\/(SICI)1096-987X(19981115)19:14<1639::AID-JCC10>3.0.CO;2-B","article-title":"Automated docking using a Lamarckian genetic algorithm and an empirical binding free energy function","volume":"19","author":"Morris","year":"1998","journal-title":"Journal of Computational Chemistry"},{"issue":"Suppl. 5","key":"10.1016\/j.carbpol.2022.119734_bb0250","doi-asserted-by":"crossref","first-page":"v4","DOI":"10.1093\/rheumatology\/ker394","article-title":"Overview of the mucopolysaccharidoses","volume":"50","author":"Muenzer","year":"2011","journal-title":"Rheumatology (Oxford)"},{"key":"10.1016\/j.carbpol.2022.119734_bb0255","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1006\/cyto.1997.0246","article-title":"Characterization of human recombinant interleukin 2 binding to heparin and heparan sulfate using an ELISA approach","volume":"9","author":"Najjam","year":"1997","journal-title":"Cytokine"},{"key":"10.1016\/j.carbpol.2022.119734_bb0260","doi-asserted-by":"crossref","first-page":"1022","DOI":"10.1016\/j.jmb.2010.06.006","article-title":"The occluding loop of cathepsin B prevents its effective inhibition by human kininogens","volume":"400","author":"Naudin","year":"2010","journal-title":"Journal of Molecular Biology"},{"key":"10.1016\/j.carbpol.2022.119734_bb0265","doi-asserted-by":"crossref","first-page":"13959","DOI":"10.1021\/ja5032776","article-title":"Folding simulations for proteins with diverse topologies are accessible in days with a physics-based force field and implicit solvent","volume":"136","author":"Nguyen","year":"2014","journal-title":"Journal of the American Chemical Society"},{"key":"10.1016\/j.carbpol.2022.119734_bb0270","doi-asserted-by":"crossref","DOI":"10.1155\/2014\/309718","article-title":"Cysteine cathepsin activity regulation by glycosaminoglycans","volume":"2014","author":"Novinec","year":"2014","journal-title":"BioMed Research International"},{"key":"10.1016\/j.carbpol.2022.119734_bb0275","doi-asserted-by":"crossref","first-page":"1297","DOI":"10.1002\/jcc.10126","article-title":"Effective born radii in the generalized born approximation: The importance of being perfect","volume":"23","author":"Onufriev","year":"2002","journal-title":"Journal of Computational Chemistry"},{"key":"10.1016\/j.carbpol.2022.119734_bb0280","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/S0022-1759(02)00295-8","article-title":"A simple method for the determination of dissociation constants by displacement ELISA","volume":"270","author":"Orosz","year":"2002","journal-title":"Journal of Immunological Methods"},{"key":"10.1016\/j.carbpol.2022.119734_bb0285","doi-asserted-by":"crossref","first-page":"11485","DOI":"10.1074\/jbc.M117.786558","article-title":"Insights into the mechanism of cystatin C oligomer and amyloid formation and its interaction with \u03b2-amyloid","volume":"292","author":"Perlenfein","year":"2017","journal-title":"The Journal of Biological Chemistry"},{"key":"10.1016\/j.carbpol.2022.119734_bb0290","doi-asserted-by":"crossref","first-page":"142","DOI":"10.4161\/biom.21316","article-title":"Functional aspects of the interaction between interleukin-8 and sulfated glycosaminoglycans","volume":"2","author":"Pichert","year":"2012","journal-title":"Biomatter"},{"key":"10.1016\/j.carbpol.2022.119734_bb0295","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1515\/bchm3.1990.371.2.575","article-title":"Different forms of human cystatin C","volume":"371","author":"Popovi\u0107","year":"1990","journal-title":"Biological Chemistry Hoppe-Seyler"},{"key":"10.1016\/j.carbpol.2022.119734_bb0300","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/S0014-5793(99)00824-8","article-title":"Cathepsin L is capable of truncating cystatin C of 11 N-terminal amino acids","volume":"455","author":"Popovic","year":"1999","journal-title":"FEBS Letters"},{"key":"10.1016\/j.carbpol.2022.119734_bb0305","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/B978-0-12-385950-1.00007-9","article-title":"Serpin-glycosaminoglycan interactions","volume":"501","author":"Rein","year":"2011","journal-title":"Methods in Enzymology"},{"key":"10.1016\/j.carbpol.2022.119734_bb0310","doi-asserted-by":"crossref","first-page":"E713","DOI":"10.3390\/molecules22050713","article-title":"Heparin, heparan sulphate and the TGF-\u03b2 cytokine superfamily","volume":"22","author":"Rider","year":"2017","journal-title":"Molecules"},{"key":"10.1016\/j.carbpol.2022.119734_bb0315","doi-asserted-by":"crossref","first-page":"4905","DOI":"10.1038\/s41598-019-41355-2","article-title":"Glycosaminoglycans influence enzyme activity of MMP2 and MMP2\/TIMP3 complex formation - insights at cellular and molecular level","volume":"9","author":"Ruiz-G\u00f3mez","year":"2019","journal-title":"Scientific Reports"},{"key":"10.1016\/j.carbpol.2022.119734_bb0320","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1021\/ci500669w","article-title":"Coarse-grained model of glycosaminoglycans","volume":"55","author":"Samsonov","year":"2015","journal-title":"Journal of Chemical Information and Modeling"},{"key":"10.1016\/j.carbpol.2022.119734_bb0325","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1007\/BF03262209","article-title":"Update on biomarkers of acute kidney injury: Moving closer to clinical impact?","volume":"16","author":"Schiffl","year":"2012","journal-title":"Molecular Diagnosis & Therapy"},{"key":"10.1016\/j.carbpol.2022.119734_bb0330","doi-asserted-by":"crossref","first-page":"1832","DOI":"10.2215\/CJN.01640309","article-title":"Measurement and estimation of GFR in children and adolescents","volume":"4","author":"Schwartz","year":"2009","journal-title":"Clinical Journal of the American Society of Nephrology"},{"key":"10.1016\/j.carbpol.2022.119734_bb0335","doi-asserted-by":"crossref","DOI":"10.3389\/fmolb.2021.639666","article-title":"Glycosaminoglycan-protein interactions and their roles in human disease","volume":"8","author":"Shi","year":"2021","journal-title":"Frontiers in Molecular Biosciences"},{"key":"10.1016\/j.carbpol.2022.119734_bb0340","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1016\/0006-291X(90)90767-H","article-title":"Transforming growth factor beta regulates cystatin C in serum-free mouse embryo (SFME) cells","volume":"172","author":"Solem","year":"1990","journal-title":"Biochemical and Biophysical Research Communications"},{"key":"10.1016\/j.carbpol.2022.119734_bb0345","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1097\/00042737-200108000-00013","article-title":"Elevation of serum cystatin C concentrations in patients with chronic liver disease","volume":"13","author":"Takeuchi","year":"2001","journal-title":"European Journal of Gastroenterology & Hepatology"},{"key":"10.1016\/j.carbpol.2022.119734_bb0350","doi-asserted-by":"crossref","first-page":"2332","DOI":"10.1111\/febs.12198","article-title":"Functional interactions between matrix metalloproteinases and glycosaminoglycans","volume":"280","author":"Tocchi","year":"2013","journal-title":"The FEBS Journal"},{"key":"10.1016\/j.carbpol.2022.119734_bb0355","doi-asserted-by":"crossref","first-page":"5406","DOI":"10.2741\/3089","article-title":"Cystatins: Biochemical and structural properties, and medical relevance","volume":"13","author":"Turk","year":"2008","journal-title":"Frontiers in Bioscience"},{"key":"10.1016\/j.carbpol.2022.119734_bb0360","doi-asserted-by":"crossref","DOI":"10.1152\/ajpcell.00095.2022","article-title":"The glycosaminoglycan interactome 2.0","author":"Vallet","year":"2022","journal-title":"American Journal of Physiology. Cell Physiology"},{"key":"10.1016\/j.carbpol.2022.119734_bb0365","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/j.jmgm.2005.12.005","article-title":"Automatic atom type and bond type perception in molecular mechanical calculations","volume":"25","author":"Wang","year":"2006","journal-title":"Journal of Molecular Graphics & Modelling"},{"key":"10.1016\/j.carbpol.2022.119734_bb0370","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1007\/8904_2012_141","article-title":"The transforming growth factor-Beta signaling pathway involvement in cardiovascular lesions in mucopolysaccharidosis-I","volume":"7","author":"Yano","year":"2013","journal-title":"JIMD Reports"},{"key":"10.1016\/j.carbpol.2022.119734_bb0375","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1038\/s42003-021-01737-7","article-title":"pH-dependent and dynamic interactions of cystatin C with heparan sulfate","volume":"4","author":"Zhang","year":"2021","journal-title":"Communications Biology"},{"key":"10.1016\/j.carbpol.2022.119734_bb0380","doi-asserted-by":"crossref","first-page":"1","DOI":"10.5582\/irdr.2020.01011","article-title":"A basic understanding of mucopolysaccharidosis: Incidence, clinical features, diagnosis, and management","volume":"9","author":"Zhou","year":"2020","journal-title":"Intractable Rare Dis Res"}],"container-title":["Carbohydrate Polymers"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0144861722006397?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0144861722006397?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T00:33:15Z","timestamp":1758933195000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0144861722006397"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,10]]},"references-count":75,"alternative-id":["S0144861722006397"],"URL":"https:\/\/doi.org\/10.1016\/j.carbpol.2022.119734","relation":{},"ISSN":["0144-8617"],"issn-type":[{"value":"0144-8617","type":"print"}],"subject":[],"published":{"date-parts":[[2022,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Binding of heparan sulfate to human cystatin C modulates inhibition of cathepsin L: Putative consequences in mucopolysaccharidosis","name":"articletitle","label":"Article Title"},{"value":"Carbohydrate Polymers","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.carbpol.2022.119734","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"119734"}}