{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T18:11:50Z","timestamp":1788545510984,"version":"build-2803163510"},"reference-count":30,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2019,2,1]],"date-time":"2019-02-01T00:00:00Z","timestamp":1548979200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"Intramural Research Program of the National Institutes of Health, National Institute on Aging (NIA)","award":["R01-AG028050"],"award-info":[{"award-number":["R01-AG028050"]}]},{"DOI":"10.13039\/100000056","name":"NINR","doi-asserted-by":"publisher","award":["R01-NR012459"],"award-info":[{"award-number":["R01-NR012459"]}],"id":[{"id":"10.13039\/100000056","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Cardiac Failure"],"published-print":{"date-parts":[[2019,2]]},"DOI":"10.1016\/j.cardfail.2018.10.015","type":"journal-article","created":{"date-parts":[[2018,11,10]],"date-time":"2018-11-10T02:23:49Z","timestamp":1541816629000},"page":"78-86","source":"Crossref","is-referenced-by-count":25,"title":["Heart Failure Epidemiology in Patients With Diabetes Mellitus Without Coronary Heart Disease"],"prefix":"10.1016","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1468-8654","authenticated-orcid":false,"given":"Hassan","family":"Khan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan D.","family":"Anker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr","given":"James L.","family":"Januzzi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Darren K.","family":"McGuire","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naveed","family":"Sattar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hans Juergen","family":"Woerle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Javed","family":"Butler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cardfail.2018.10.015_bib0001","doi-asserted-by":"crossref","first-page":"1830","DOI":"10.1161\/CIRCRESAHA.116.306924","article-title":"Heart failure considerations of antihyperglycemic medications for type 2 diabetes","volume":"118","author":"Standl","year":"2016","journal-title":"Circ Res"},{"key":"10.1016\/j.cardfail.2018.10.015_bib0002","doi-asserted-by":"crossref","first-page":"1186","DOI":"10.1016\/j.ijcard.2012.11.065","article-title":"Worldwide risk factors for heart failure: a systematic review and pooled analysis","volume":"168","author":"Khatibzadeh","year":"2013","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.cardfail.2018.10.015_bib0003","doi-asserted-by":"crossref","first-page":"444","DOI":"10.4239\/wjd.v5.i4.444","article-title":"Type 2 diabetes and cardiovascular disease: Have all risk factors the same strength?","volume":"5","author":"Martin-Timon","year":"2014","journal-title":"World J Diabetes"},{"key":"10.1016\/j.cardfail.2018.10.015_bib0004","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1056\/NEJMoa1501352","article-title":"Effect of sitagliptin on cardiovascular outcomes in type 2 diabetes","volume":"373","author":"Green","year":"2015","journal-title":"N Engl J Med"},{"key":"10.1016\/j.cardfail.2018.10.015_bib0005","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1056\/NEJMoa1203858","article-title":"Basal insulin and cardiovascular and other outcomes in dysglycemia","volume":"367","author":"Gerstein","year":"2012","journal-title":"N Engl J Med"},{"key":"10.1016\/j.cardfail.2018.10.015_bib0006","doi-asserted-by":"crossref","first-page":"1317","DOI":"10.1056\/NEJMoa1307684","article-title":"Saxagliptin and cardiovascular outcomes in patients with type 2 diabetes mellitus","volume":"369","author":"Scirica","year":"2013","journal-title":"N Engl J Med"},{"key":"10.1016\/j.cardfail.2018.10.015_bib0007","doi-asserted-by":"crossref","first-page":"1327","DOI":"10.1056\/NEJMoa1305889","article-title":"Alogliptin after acute coronary syndrome in patients with type 2 diabetes","volume":"369","author":"White","year":"2013","journal-title":"N Engl J Med"},{"key":"10.1016\/j.cardfail.2018.10.015_bib0008","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1007\/s00059-008-3115-3","article-title":"Cardiomyopathy in type 2 diabetes: update on pathophysiological mechanisms","volume":"33","author":"Saunders","year":"2008","journal-title":"Herz"},{"key":"10.1016\/j.cardfail.2018.10.015_bib0009","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1001\/archinternmed.2009.40","article-title":"Epidemiology of incident heart failure in a contemporary elderly cohort: the health, aging, and body composition study","volume":"169","author":"Kalogeropoulos","year":"2009","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.cardfail.2018.10.015_bib0010","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/1047-2797(91)90005-W","article-title":"The Cardiovascular Health Study: design and rationale","volume":"1","author":"Fried","year":"1991","journal-title":"Ann Epidemiol"},{"key":"10.1016\/j.cardfail.2018.10.015_bib0011","doi-asserted-by":"crossref","first-page":"2460","DOI":"10.1001\/archinte.165.21.2460","article-title":"Subclinical hypothyroidism and the risk of heart failure, other cardiovascular events, and death","volume":"165","author":"Rodondi","year":"2005","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.cardfail.2018.10.015_bib0012","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1002\/ejhf.69","article-title":"Incident heart failure in relation to vascular disease: insights from the Health, Aging, and Body Composition Study","volume":"16","author":"Khan","year":"2014","journal-title":"Eur J Heart Fail"},{"key":"10.1016\/j.cardfail.2018.10.015_bib0013","doi-asserted-by":"crossref","first-page":"e50","DOI":"10.1016\/j.jacc.2010.09.001","article-title":"2010 ACCF\/AHA guideline for assessment of cardiovascular risk in asymptomatic adults: a report of the American College of Cardiology Foundation\/American Heart Association Task Force on Practice Guidelines","volume":"56","author":"Greenland","year":"2010","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.cardfail.2018.10.015_bib0014","doi-asserted-by":"crossref","first-page":"461","DOI":"10.7326\/0003-4819-130-6-199903160-00002","article-title":"A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation. Modification of Diet in Renal Disease Study Group","volume":"130","author":"Levey","year":"1999","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.cardfail.2018.10.015_bib0015","doi-asserted-by":"crossref","first-page":"1628","DOI":"10.1016\/S0735-1097(00)00582-9","article-title":"Predictors of congestive heart failure in the elderly: the Cardiovascular Health Study","volume":"35","author":"Gottdiener","year":"2000","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.cardfail.2018.10.015_bib0016","doi-asserted-by":"crossref","first-page":"1628","DOI":"10.1016\/S0735-1097(00)00582-9","article-title":"Predictors of congestive heart failure in the elderly: the Cardiovascular Health Study","volume":"35","author":"Gottdiener","year":"2000","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.cardfail.2018.10.015_bib0017","doi-asserted-by":"crossref","first-page":"3068","DOI":"10.1161\/01.CIR.0000039105.49749.6F","article-title":"Lifetime risk for developing congestive heart failure: the Framingham Heart Study","volume":"106","author":"Lloyd-Jones","year":"2002","journal-title":"Circulation"},{"key":"10.1016\/j.cardfail.2018.10.015_bib0018","first-page":"1","article-title":"2006 National Hospital Discharge Survey","author":"DeFrances","year":"2008","journal-title":"Natl Health Stat Report"},{"key":"10.1016\/j.cardfail.2018.10.015_bib0019","first-page":"e2","article-title":"Heart disease and stroke statistics\u20142012 update: a report from the American Heart Association","volume":"125","author":"Roger","year":"2012","journal-title":"Circulation"},{"key":"10.1016\/j.cardfail.2018.10.015_bib0020","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/j.arr.2010.11.002","article-title":"Inflammatory markers in population studies of aging","volume":"10","author":"Singh","year":"2011","journal-title":"Ageing Res Rev"},{"key":"10.1016\/j.cardfail.2018.10.015_bib0021","doi-asserted-by":"crossref","first-page":"2129","DOI":"10.1016\/j.jacc.2009.12.045","article-title":"Inflammatory markers and incident heart failure risk in older adults: the Health ABC (Health, Aging, and Body Composition) Study","volume":"55","author":"Kalogeropoulos","year":"2010","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.cardfail.2018.10.015_bib0022","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.hfc.2011.08.002","article-title":"From risk factors to structural heart disease: the role of inflammation","volume":"8","author":"Kalogeropoulos","year":"2012","journal-title":"Heart Fail Clin"},{"key":"10.1016\/j.cardfail.2018.10.015_bib0023","doi-asserted-by":"crossref","first-page":"2673","DOI":"10.1113\/jphysiol.2008.154229","article-title":"Reduced vascular tetrahydrobiopterin (BH4) and endothelial function with ageing: is it time for a chronic BH4 supplementation trial in middle-aged and older adults?","volume":"586","author":"Pierce","year":"2008","journal-title":"J Physiol"},{"key":"10.1016\/j.cardfail.2018.10.015_bib0024","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.113.000426","article-title":"Peripheral endothelial function and cardiovascular events in high-risk patients","volume":"2","author":"Matsuzawa","year":"2013","journal-title":"J Am Heart Assoc"},{"key":"10.1016\/j.cardfail.2018.10.015_bib0025","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1161\/CIRCHEARTFAILURE.108.828343","article-title":"Association between elevated fibrosis markers and heart failure in the elderly: the cardiovascular health study","volume":"2","author":"Barasch","year":"2009","journal-title":"Circ Heart Fail"},{"key":"10.1016\/j.cardfail.2018.10.015_bib0026","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.1016\/S0047-6374(01)00238-X","article-title":"Age related changes of the collagen network of the human heart","volume":"122","author":"Gazoti Debessa","year":"2001","journal-title":"Mech Ageing Dev"},{"key":"10.1016\/j.cardfail.2018.10.015_bib0027","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1161\/CIRCULATIONAHA.111.025270","article-title":"Diabetes mellitus worsens diastolic left ventricular dysfunction in aortic stenosis through altered myocardial structure and cardiomyocyte stiffness","volume":"124","author":"Falcao-Pires","year":"2011","journal-title":"Circulation"},{"key":"10.1016\/j.cardfail.2018.10.015_bib0028","doi-asserted-by":"crossref","first-page":"2483","DOI":"10.1097\/HJH.0b013e3283316c4d","article-title":"Relation of circulating markers of fibrosis and progression of left and right ventricular dysfunction in hypertensive patients with heart failure","volume":"27","author":"Plaksej","year":"2009","journal-title":"J Hypertens"},{"key":"10.1016\/j.cardfail.2018.10.015_bib0029","doi-asserted-by":"crossref","first-page":"907","DOI":"10.7326\/0003-4819-138-11-200306030-00012","article-title":"The epidemiology of \u201casymptomatic\u201d left ventricular systolic dysfunction: implications for screening","volume":"138","author":"Wang","year":"2003","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.cardfail.2018.10.015_bib0030","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/j.cardfail.2008.12.002","article-title":"The role of N-terminal pro\u2013brain natriuretic peptide and echocardiography for screening asymptomatic left ventricular dysfunction in a population at high risk for heart failure. The PROBE-HF study","volume":"15","author":"Betti","year":"2009","journal-title":"J Card Fail"}],"container-title":["Journal of Cardiac Failure"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1071916418311205?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1071916418311205?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,9,24]],"date-time":"2019-09-24T00:42:51Z","timestamp":1569285771000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1071916418311205"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,2]]},"references-count":30,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2019,2]]}},"alternative-id":["S1071916418311205"],"URL":"https:\/\/doi.org\/10.1016\/j.cardfail.2018.10.015","relation":{},"ISSN":["1071-9164"],"issn-type":[{"value":"1071-9164","type":"print"}],"subject":[],"published":{"date-parts":[[2019,2]]}}}