{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T00:23:42Z","timestamp":1761092622647,"version":"build-2065373602"},"reference-count":90,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","onlinejcf.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Cardiac Failure"],"published-print":{"date-parts":[[2020,1]]},"DOI":"10.1016\/j.cardfail.2019.08.011","type":"journal-article","created":{"date-parts":[[2019,8,26]],"date-time":"2019-08-26T11:54:18Z","timestamp":1566820458000},"page":"85-92","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["A Compelling Case for Less Aggressive Arrhythmia Management in Patients With Chronic Heart Failure and Long-Standing Atrial Fibrillation"],"prefix":"10.1016","volume":"26","author":[{"given":"Milton","family":"Packer","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.cardfail.2019.08.011_bib0001","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1016\/j.jchf.2017.05.001","article-title":"Atrial fibrillation in heart failure with preserved, mid-range, and reduced ejection fraction","volume":"5","author":"Sartipy","year":"2017","journal-title":"JACC Heart Fail"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0002","doi-asserted-by":"crossref","first-page":"2490","DOI":"10.1016\/j.jacc.2017.09.027","article-title":"Type of atrial fibrillation and outcomes in patients with heart failure and reduced ejection fraction","volume":"70","author":"Mogensen","year":"2017","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0003","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1161\/01.CIR.89.2.724","article-title":"Echocardiographic predictors of nonrheumatic atrial fibrillation: the Framingham Heart Study","volume":"89","author":"Vaziri","year":"1994","journal-title":"Circulation"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0004","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1016\/S0735-1097(99)00563-X","article-title":"Prediction of paroxysmal atrial fibrillation in patients with congestive heart failure: a prospective study","volume":"35","author":"Yamada","year":"2000","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0005","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1002\/jcu.22521","article-title":"Mitral regurgitation severity correlates with symptoms and extent of left atrial dysfunction: effect of mitral valve repair","volume":"46","author":"Lisi","year":"2018","journal-title":"J Clin Ultrasound"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0006","first-page":"45","article-title":"Association between low-grade chronic inflammation and depressed left atrial compliance in heart failure with preserved ejection fraction: a retrospective analysis","volume":"58","author":"Sani","year":"2018","journal-title":"Folia Med Cracov"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0007","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1016\/j.jacep.2017.07.004","article-title":"Assessment of left atrial fibrosis by late gadolinium enhancement magnetic resonance imaging: methodology and clinical implications","volume":"3","author":"Siebermair","year":"2017","journal-title":"JACC Clin Electrophysiol"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0008","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/j.ijcard.2017.07.007","article-title":"Left atrial fibrosis is associated with new-onset heart failure in patients with atrial fibrillation","volume":"248","author":"Azadani","year":"2017","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0009","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCIMAGING.114.002769","article-title":"Association of left atrial function and left atrial enhancement in patients with atrial fibrillation: cardiac magnetic resonance study","volume":"8","author":"Habibi","year":"2015","journal-title":"Circ Cardiovasc Imaging"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0010","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1161\/CIRCIMAGING.109.865683","article-title":"Left atrial strain and strain rate in patients with paroxysmal and persistent atrial fibrillation: relationship to left atrial structural remodeling detected by delayed-enhancement MRI","volume":"3","author":"Kuppahally","year":"2010","journal-title":"Circ Cardiovasc Imaging"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0011","doi-asserted-by":"crossref","DOI":"10.1177\/2050312118799908","article-title":"Opposite relations of epicardial adipose tissue to left atrial size in paroxysmal and permanent atrial fibrillation","volume":"6","author":"Psychari","year":"2018","journal-title":"SAGE Open Med"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0012","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1161\/CIRCHEARTFAILURE.114.001667","article-title":"Left atrial remodeling and function in advanced heart failure with preserved or reduced ejection fraction","volume":"8","author":"Melenovsky","year":"2015","journal-title":"Circ Heart Fail"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0013","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1007\/s10741-017-9644-1","article-title":"Epicardial adipose tissue as a metabolic transducer: role in heart failure and coronary artery disease","volume":"22","author":"Patel","year":"2017","journal-title":"Heart Fail Rev"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0014","doi-asserted-by":"crossref","first-page":"1567","DOI":"10.1002\/ejhf.1294","article-title":"The epicardial adipose inflammatory triad: coronary atherosclerosis, atrial fibrillation, and heart failure with a preserved ejection fraction","volume":"20","author":"Packer","year":"2018","journal-title":"Eur J Heart Fail"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0015","doi-asserted-by":"crossref","first-page":"2360","DOI":"10.1016\/j.jacc.2018.03.509","article-title":"Epicardial adipose tissue may mediate deleterious effects of obesity and inflammation on the myocardium","volume":"71","author":"Packer","year":"2018","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0016","doi-asserted-by":"crossref","first-page":"1529","DOI":"10.1016\/j.jacep.2018.08.014","article-title":"Electroanatomical remodeling of the atria in obesity: impact of adjacent epicardial fat","volume":"4","author":"Mahajan","year":"2018","journal-title":"JACC Clin Electrophysiol"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0017","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCIMAGING.114.002769","article-title":"Association of left atrial function and left atrial enhancement in patients with atrial fibrillation: cardiac magnetic resonance study","volume":"8","author":"Habibi","year":"2015","journal-title":"Circ Cardiovasc Imaging"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0018","doi-asserted-by":"crossref","first-page":"3027","DOI":"10.1007\/s00330-018-5793-4","article-title":"Left atrial epicardial adipose tissue radiodensity is associated with electrophysiological properties of atrial myocardium in patients with atrial fibrillation","volume":"29","author":"Klein","year":"2019","journal-title":"Eur Radiol"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0019","doi-asserted-by":"crossref","first-page":"758","DOI":"10.1111\/echo.12733","article-title":"Association of left atrial booster-pump function with heart failure symptoms in patients with severe aortic stenosis and preserved left ventricular ejection fraction","volume":"32","author":"Imanishi","year":"2015","journal-title":"Echocardiography"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0020","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1093\/eurheartj\/ehu405","article-title":"Left atrial function measured by cardiac magnetic resonance imaging in patients with heart failure: clinical associations and prognostic value","volume":"36","author":"Pellicori","year":"2015","journal-title":"Eur Heart J"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0021","article-title":"Influence of left atrial function on exercise capacity and left ventricular function in patients with heart failure and preserved ejection fraction","volume":"10","author":"von Roeder","year":"2017","journal-title":"Circ Cardiovasc Imaging"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0022","doi-asserted-by":"crossref","first-page":"1307","DOI":"10.1002\/ejhf.645","article-title":"Global left atrial failure in heart failure","volume":"18","author":"Triposkiadis","year":"2016","journal-title":"Eur J Heart Fail"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0023","doi-asserted-by":"crossref","first-page":"1138","DOI":"10.1016\/S0002-9149(98)00134-9","article-title":"Left atrial mechanical adaptation to long-standing hemodynamic loads based on pressure-volume relations","volume":"81","author":"Dernellis","year":"1998","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0024","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1007\/s10840-016-0131-8","article-title":"Changes in left ventricular filling parameters following catheter ablation of atrial fibrillation","volume":"47","author":"Krezowski","year":"2016","journal-title":"J Interv Card Electrophysiol"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0025","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1093\/eurheartj\/ehi066","article-title":"Functional impact of rate irregularity in patients with heart failure and atrial fibrillation receiving cardiac resynchronization therapy","volume":"26","author":"Melenovsky","year":"2005","journal-title":"Eur Heart J"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0026","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCEP.119.007222","article-title":"What have we learned from randomized controlled trials of catheter ablation for atrial fibrillation in patients with chronic heart failure?","volume":"12","author":"Packer","year":"2019","journal-title":"Circ Arrhythm Electrophys"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0027","doi-asserted-by":"crossref","first-page":"1949","DOI":"10.1016\/j.jacc.2017.08.041","article-title":"Catheter ablation versus medical rate control in atrial fibrillation and systolic dysfunction: the CAMERA-MRI study","volume":"70","author":"Prabhu","year":"2017","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0028","doi-asserted-by":"crossref","first-page":"740","DOI":"10.1136\/hrt.2010.207340","article-title":"Radiofrequency ablation for persistent atrial fibrillation in patients with advanced heart failure and severe left ventricular systolic dysfunction: a randomised controlled trial","volume":"97","author":"MacDonald","year":"2011","journal-title":"Heart"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0029","doi-asserted-by":"crossref","first-page":"1785","DOI":"10.1016\/j.jacc.2011.12.044","article-title":"Association of heart rate and outcomes in a broad spectrum of patients with chronic heart failure: results from the CHARM (Candesartan in Heart Failure: Assessment of Reduction in Mortality and morbidity) program","volume":"59","author":"Castagno","year":"2012","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0030","doi-asserted-by":"crossref","first-page":"1030","DOI":"10.1001\/jama.2015.10725","article-title":"Assessment of the CHA2DS2-VASc score in predicting ischemic stroke, thromboembolism, and death in patients with heart failure with and without atrial fibrillation","volume":"314","author":"Melgaard","year":"2015","journal-title":"JAMA"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0031","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1007\/s10741-014-9420-4","article-title":"Atrial fibrillation in heart failure: stroke risk stratification and anticoagulation","volume":"19","author":"Abraham","year":"2014","journal-title":"Heart Fail Rev"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0032","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1016\/j.cardfail.2007.02.009","article-title":"The safety of amiodarone in patients with heart failure","volume":"13","author":"Torp-Pedersen","year":"2007","journal-title":"J Card Fail"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0033","doi-asserted-by":"crossref","first-page":"2268","DOI":"10.1056\/NEJMoa1109867","article-title":"Dronedarone in high-risk permanent atrial fibrillation","volume":"365","author":"Connolly","year":"2011","journal-title":"N Engl J Med"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0034","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/S0140-6736(96)02149-6","article-title":"Effect of d-sotalol on mortality in patients with left ventricular dysfunction after recent and remote myocardial infarction","volume":"348","author":"Waldo","year":"1996","journal-title":"Lancet"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0035","doi-asserted-by":"crossref","first-page":"2667","DOI":"10.1056\/NEJMoa0708789","article-title":"Rhythm control versus rate control for atrial fibrillation and heart failure","volume":"358","author":"Roy","year":"2008","journal-title":"N Engl J Med"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0036","doi-asserted-by":"crossref","first-page":"1825","DOI":"10.1056\/NEJMoa021328","article-title":"A comparison of rate control and rhythm control in patients with atrial fibrillation","volume":"347","author":"Wyse","year":"2002","journal-title":"N Engl J Med"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0037","doi-asserted-by":"crossref","first-page":"1834","DOI":"10.1056\/NEJMoa021375","article-title":"A comparison of rate control and rhythm control in patients with recurrent persistent atrial fibrillation","volume":"347","author":"Van Gelder","year":"2002","journal-title":"N Engl J Med"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0038","doi-asserted-by":"crossref","first-page":"960","DOI":"10.1007\/s00392-017-1146-6","article-title":"Adherence to optimal heart rate control in heart failure with reduced ejection fraction: insight from a survey of heart rate in heart failure in Sweden (HR-HF study)","volume":"106","author":"Fu","year":"2017","journal-title":"Clin Res Cardiol"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0039","doi-asserted-by":"crossref","first-page":"2885","DOI":"10.1016\/j.jacc.2017.04.001","article-title":"Heart rate and rhythm and the benefit of beta-blockers in patients with heart failure","volume":"69","author":"Kotecha","year":"2017","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0040","doi-asserted-by":"crossref","first-page":"2215","DOI":"10.1016\/j.clinthera.2015.08.017","article-title":"Should \u03b2-blockers be used in patients with heart failure and atrial fibrillation?","volume":"37","author":"Mareev","year":"2015","journal-title":"Clin Ther"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0041","doi-asserted-by":"crossref","first-page":"2667","DOI":"10.1056\/NEJMoa0708789","article-title":"Rhythm control versus rate control for atrial fibrillation and heart failure","volume":"358","author":"Roy","year":"2008","journal-title":"N Engl J Med"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0042","doi-asserted-by":"crossref","first-page":"1311","DOI":"10.1093\/eurjhf\/hft093","article-title":"Lenient vs. strict rate control in patients with atrial fibrillation and heart failure: a post-hoc analysis of the RACE II study","volume":"15","author":"Mulder","year":"2013","journal-title":"Eur J Heart Fail"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0043","doi-asserted-by":"crossref","first-page":"2235","DOI":"10.1016\/S0140-6736(14)61373-8","article-title":"Efficacy of \u03b2 blockers in patients with heart failure plus atrial fibrillation: an individual-patient data meta-analysis","volume":"384","author":"Kotecha","year":"2014","journal-title":"Lancet"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0044","doi-asserted-by":"crossref","first-page":"1481","DOI":"10.1093\/eurheartj\/ehs348","article-title":"Increased mortality among patients taking digoxin: analysis from the AFFIRM study","volume":"34","author":"Whitbeck","year":"2013","journal-title":"Eur Heart J"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0045","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1161\/CIRCEP.114.002046","article-title":"Interaction between digoxin and dronedarone in the PALLAS trial","volume":"7","author":"Hohnloser","year":"2014","journal-title":"Circ Arrhythm Electrophysiol"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0046","doi-asserted-by":"crossref","first-page":"1336","DOI":"10.1016\/j.hrthm.2014.04.015","article-title":"Troponin elevation after radiofrequency catheter ablation of atrial fibrillation: relevance to AF substrate, procedural outcomes, and reverse structural remodeling","volume":"11","author":"Yoshida","year":"2014","journal-title":"Heart Rhythm"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0047","doi-asserted-by":"crossref","first-page":"1436","DOI":"10.1016\/j.jacc.2006.10.076","article-title":"Prevalence and severity of left atrial edema detected by electron beam tomography early after pulmonary vein ablation","volume":"49","author":"Okada","year":"2007","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0048","doi-asserted-by":"crossref","first-page":"1873","DOI":"10.1093\/eurheartj\/ehz284","article-title":"Effect of catheter ablation on pre-existing abnormalities of left atrial systolic, diastolic, and neurohormonal functions in patients with chronic heart failure and atrial fibrillation","volume":"40","author":"Packer","year":"2019","journal-title":"Eur Heart J"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0049","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1016\/j.hrthm.2008.02.008","article-title":"Left atrial function and scar after catheter ablation of atrial fibrillation","volume":"5","author":"Wylie","year":"2008","journal-title":"Heart Rhythm"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0050","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1111\/jce.12449","article-title":"Atrial structure and function 5 years after successful ablation for persistent atrial fibrillation: an MRI study","volume":"25","author":"Cochet","year":"2014","journal-title":"J Cardiovasc Electrophysiol"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0051","doi-asserted-by":"crossref","first-page":"1306","DOI":"10.1016\/j.jacc.2006.11.033","article-title":"Effects of stepwise ablation of chronic atrial fibrillation on atrial electrical and mechanical properties","volume":"49","author":"Takahashi","year":"2007","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0052","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1111\/jce.13128","article-title":"Changes in left atrial transport function in patients who maintained sinus rhythm after successful radiofrequency catheter ablation for atrial fibrillation: a 1-year follow-up multislice computed tomography study","volume":"28","author":"Kim","year":"2017","journal-title":"J Cardiovasc Electrophysiol"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0053","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1111\/jce.13387","article-title":"The impact of elevated left atrial pressure in sinus rhythm after cardioversion on outcomes after catheter ablation for atrial fibrillation","volume":"29","author":"Kishima","year":"2018","journal-title":"J Cardiovasc Electrophysiol"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0054","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1016\/j.hrthm.2014.03.009","article-title":"High left atrial pressures are associated with advanced electroanatomical remodeling of left atrium and independent predictors for clinical recurrence of atrial fibrillation after catheter ablation","volume":"11","author":"Park","year":"2014","journal-title":"Heart Rhythm"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0055","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1016\/j.hrthm.2014.03.047","article-title":"The inconvenient truth of elevated left atrial pressure and AF recurrence despite catheter ablation","volume":"11","author":"Kumar","year":"2014","journal-title":"Heart Rhythm"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0056","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1093\/europace\/euv215","article-title":"Incidence and risk factors for symptomatic heart failure after catheter ablation of atrial fibrillation and atrial flutter","volume":"18","author":"Huang","year":"2016","journal-title":"Europace"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0057","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1007\/s10840-014-9875-1","article-title":"Increase in pulmonary arterial pressure after atrial fibrillation ablation: incidence and associated findings","volume":"40","author":"Witt","year":"2014","journal-title":"J Interv Card Electrophysiol"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0058","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.117.006313","article-title":"Atrial fibrosis by late gadolinium enhancement magnetic resonance imaging and catheter ablation of atrial fibrillation: 5-year follow-up data","volume":"7","author":"Chelu","year":"2018","journal-title":"J Am Heart Assoc"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0059","doi-asserted-by":"crossref","first-page":"13618","DOI":"10.1038\/s41598-018-31916-2","article-title":"Cardiac magnetic resonance using late gadolinium enhancement and atrial T1 mapping predicts poor outcome in patients with atrial fibrillation after catheter ablation therapy","volume":"8","author":"Luetkens","year":"2018","journal-title":"Sci Rep"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0060","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/j.jacc.2019.01.011","volume":"74","author":"January","year":"2019","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0061","doi-asserted-by":"crossref","first-page":"1894","DOI":"10.1016\/j.jacc.2013.01.069","article-title":"A randomized trial to assess catheter ablation versus rate control in the management of persistent atrial fibrillation in heart failure","volume":"61","author":"Jones","year":"2013","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0062","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1161\/CIRCEP.113.000806","article-title":"A randomized controlled trial of catheter ablation versus medical treatment of atrial fibrillation in heart failure (the CAMTAF trial)","volume":"7","author":"Hunter","year":"2014","journal-title":"Circ Arrhythm Electrophysiol"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0063","doi-asserted-by":"crossref","first-page":"1637","DOI":"10.1161\/CIRCULATIONAHA.115.019406","article-title":"Ablation versus amiodarone for treatment of persistent atrial fibrillation in patients with congestive heart failure and an implanted device: Results from the AATAC multicenter randomized trial","volume":"133","author":"Di Biase","year":"2016","journal-title":"Circulation"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0064","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1056\/NEJMoa1707855","article-title":"Catheter ablation for atrial fibrillation with heart failure","volume":"378","author":"Marrouche","year":"2018","journal-title":"N Engl J Med"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0065","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1161\/CIRCULATIONAHA.118.034583","article-title":"Building castles in the sky. Catheter ablation in patients with atrial fibrillation and chronic heart failure","volume":"138","author":"Packer","year":"2018","journal-title":"Circulation"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0066","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.1001\/jama.2019.0693","article-title":"Effect of catheter ablation vs antiarrhythmic drug therapy on mortality, stroke, bleeding, and cardiac arrest among patients with atrial fibrillation: the CABANA randomized clinical trial","volume":"321","author":"Packer","year":"2019","journal-title":"JAMA"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0067","doi-asserted-by":"crossref","first-page":"e13074","DOI":"10.1097\/MD.0000000000013074","article-title":"Clinical characteristics and thromboembolic risk of atrial fibrillation patients with and without congestive heart failure. Results from the CRATF study","volume":"97","author":"Balsam","year":"2018","journal-title":"Medicine"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0068","doi-asserted-by":"crossref","first-page":"e137","DOI":"10.1161\/CIR.0000000000000509","volume":"136","author":"Yancy","year":"2017","journal-title":"Circulation"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0069","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1161\/CIRCULATIONAHA.114.013255","article-title":"Regional variation in patients and outcomes in the treatment of preserved cardiac function heart failure with an aldosterone antagonist (TOPCAT) trial","volume":"131","author":"Pfeffer","year":"2015","journal-title":"Circulation"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0070","doi-asserted-by":"crossref","first-page":"1387","DOI":"10.1016\/S0140-6736(12)61227-6","article-title":"The angiotensin receptor neprilysin inhibitor LCZ696 in heart failure with preserved ejection fraction: a phase 2 double-blind randomised controlled trial","volume":"380","author":"Solomon","year":"2012","journal-title":"Lancet"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0071","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1016\/j.jchf.2018.01.009","article-title":"Obesity-related heart failure with a preserved ejection fraction: the mechanistic rationale for combining inhibitors of aldosterone, neprilysin, and sodium-glucose cotransporter-2","volume":"6","author":"Packer","year":"2018","journal-title":"JACC Heart Fail"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0072","doi-asserted-by":"crossref","first-page":"1567","DOI":"10.1002\/ejhf.1294","article-title":"The epicardial adipose inflammatory triad: coronary atherosclerosis, atrial fibrillation, and heart failure with a preserved ejection fraction","volume":"20","author":"Packer","year":"2018","journal-title":"Eur J Heart Fail"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0073","doi-asserted-by":"crossref","first-page":"2497","DOI":"10.1016\/j.jacc.2016.09.940","article-title":"Bariatric surgery and the risk of new-onset atrial fibrillation in Swedish obese subjects","volume":"68","author":"Jamaly","year":"2016","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0074","doi-asserted-by":"crossref","first-page":"2022","DOI":"10.1016\/j.jacc.2017.09.002","article-title":"Obesity and atrial fibrillation prevalence, pathogenesis, and prognosis: effects of weight loss and exercise","volume":"70","author":"Lavie","year":"2017","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0075","doi-asserted-by":"crossref","first-page":"1504","DOI":"10.1093\/eurheartj\/ehy837","article-title":"Age threshold for the use of non-vitamin K antagonist oral anticoagulants for stroke prevention in patients with atrial fibrillation: insights into the optimal assessment of age and incident comorbidities","volume":"40","author":"Chao","year":"2019","journal-title":"Eur Heart J"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0076","doi-asserted-by":"crossref","first-page":"1030","DOI":"10.1001\/jama.2015.10725","article-title":"Assessment of the CHA2DS2-VASc score in predicting ischemic stroke, thromboembolism, and death in patients with heart failure with and without atrial fibrillation","volume":"314","author":"Melgaard","year":"2015","journal-title":"JAMA"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0077","doi-asserted-by":"crossref","first-page":"1192","DOI":"10.1002\/ejhf.343","article-title":"Non-vitamin K antagonist oral anticoagulants (NOACs) in patients with concomitant atrial fibrillation and heart failure: a systemic review and meta-analysis of randomized trials","volume":"17","author":"Xiong","year":"2015","journal-title":"Eur J Heart Fail"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0078","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1016\/0735-1097(93)90688-W","article-title":"Hematologic correlates of left atrial spontaneous echo contrast and thromboembolism in nonvalvular atrial fibrillation","volume":"21","author":"Black","year":"1993","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0079","doi-asserted-by":"crossref","first-page":"1622","DOI":"10.1016\/S0735-1097(98)00146-6","article-title":"Transesophageal echocardiographic correlates of clinical risk of thromboembolism in nonvalvular atrial fibrillation","volume":"31","author":"Zabalgoitia","year":"1998","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0080","doi-asserted-by":"crossref","first-page":"3554","DOI":"10.1161\/STROKEAHA.115.011273","article-title":"Left atrial appendage function and stroke risk","volume":"46","author":"Yaghi","year":"2015","journal-title":"Stroke"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0081","doi-asserted-by":"crossref","first-page":"2854","DOI":"10.1161\/01.CIR.0000039327.11661.16","article-title":"Downregulation of endocardial nitric oxide synthase expression and nitric oxide production in atrial fibrillation: potential mechanisms for atrial thrombosis and stroke","volume":"106","author":"Cai","year":"2002","journal-title":"Circulation"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0082","doi-asserted-by":"crossref","first-page":"1104","DOI":"10.1111\/jce.12199","article-title":"Association of atrial fibrosis quantified using LGE-MRI with atrial appendage thrombus and spontaneous contrast on transesophageal echocardiography in patients with atrial fibrillation","volume":"24","author":"Akoum","year":"2013","journal-title":"J Cardiovasc Electrophysiol"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0083","article-title":"Different influence of cardiac hemodynamics on thromboembolic events in patients with paroxysmal and non-paroxysmal atrial fibrillation","volume":"14","author":"Kim","year":"2019","journal-title":"PLoS One"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0084","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1056\/NEJMoa1105575","article-title":"Subclinical atrial fibrillation and the risk of stroke","volume":"366","author":"Healey","year":"2012","journal-title":"N Engl J Med"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0085","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1161\/STROKEAHA.109.571455","article-title":"Incidence of newly detected atrial arrhythmias via implantable devices in patients with a history of thromboembolic events","volume":"41","author":"Ziegler","year":"2010","journal-title":"Stroke"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0086","doi-asserted-by":"crossref","first-page":"2478","DOI":"10.1056\/NEJMoa1313600","article-title":"Cryptogenic stroke and underlying atrial fibrillation","volume":"370","author":"Sanna","year":"2014","journal-title":"N Engl J Med"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0087","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/j.jcmg.2012.10.019","article-title":"LA volumes and reservoir function are associated with subclinical cerebrovascular disease: the CABL (cardiovascular abnormalities and brain lesions) study","volume":"6","author":"Russo","year":"2013","journal-title":"JACC Cardiovasc Imaging"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0088","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1016\/j.jacc.2010.09.049","article-title":"Association of left atrial fibrosis detected by delayed-enhancement magnetic resonance imaging and the risk of stroke in patients with atrial fibrillation","volume":"57","author":"Daccarett","year":"2011","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0089","doi-asserted-by":"crossref","first-page":"2000","DOI":"10.1093\/eurheartj\/ehi306","article-title":"Rate-control vs. rhythm-control in patients with atrial fibrillation: a meta-analysis","volume":"26","author":"Testa","year":"2005","journal-title":"Eur Heart J"},{"key":"10.1016\/j.cardfail.2019.08.011_bib0090","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1001\/jamacardio.2019.1049","article-title":"Association of rivaroxaban with thromboembolic events in patients with heart failure, coronary disease, and sinus rhythm: a post hoc analysis of the COMMANDER HF trial","volume":"4","author":"Greenberg","year":"2019","journal-title":"JAMA Cardiol"}],"container-title":["Journal of Cardiac Failure"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1071916419306487?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1071916419306487?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T06:43:43Z","timestamp":1761029023000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1071916419306487"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,1]]},"references-count":90,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2020,1]]}},"alternative-id":["S1071916419306487"],"URL":"https:\/\/doi.org\/10.1016\/j.cardfail.2019.08.011","relation":{},"ISSN":["1071-9164"],"issn-type":[{"type":"print","value":"1071-9164"}],"subject":[],"published":{"date-parts":[[2020,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A Compelling Case for Less Aggressive Arrhythmia Management in Patients With Chronic Heart Failure and Long-Standing Atrial Fibrillation","name":"articletitle","label":"Article Title"},{"value":"Journal of Cardiac Failure","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cardfail.2019.08.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}