{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T08:12:36Z","timestamp":1791360756916,"version":"4.3.1"},"reference-count":23,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","onlinejcf.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Cardiac Failure"],"published-print":{"date-parts":[[2025,4]]},"DOI":"10.1016\/j.cardfail.2024.08.044","type":"journal-article","created":{"date-parts":[[2024,8,30]],"date-time":"2024-08-30T13:43:22Z","timestamp":1725025402000},"page":"651-660","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":15,"title":["Rationale and Design of the DECONGEST (Diuretic Treatment in Acute Heart Failure With Volume Overload Guided by Serial Spot Urine Sodium Assessment) Study"],"prefix":"10.1016","volume":"31","author":[{"given":"SIMON","family":"VANHENTENRIJK","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"JOHAN","family":"VERBEECK","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"THEODOROS","family":"KALPAKOS","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"VINCENT","family":"VANDOREN","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"LAURA","family":"BRAECKEVELDT","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"WOUTER","family":"L'HOYES","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ELEFTHERIOS","family":"CHOUSTOULAKIS","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"BRAM","family":"ROOSENS","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W.H. WILSON","family":"TANG","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"JAN","family":"VERWERFT","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0599-9290","authenticated-orcid":false,"given":"FREDERIK H.","family":"VERBRUGGE","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cardfail.2024.08.044_bib0001","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/j.ahj.2004.08.005","article-title":"Characteristics and outcomes of patients hospitalized for heart failure in the United States: rationale, design, and preliminary observations from the first 100,000 cases in the Acute Decompensated Heart Failure National Registry (ADHERE)","volume":"149","author":"Adams","year":"2005","journal-title":"Am Heart J"},{"key":"10.1016\/j.cardfail.2024.08.044_bib0002","first-page":"379","article-title":"Editor's choice: Diuretic resistance in acute heart failure","volume":"7","author":"Verbrugge","year":"2018","journal-title":"Eur Heart J Acute Cardiovasc Care"},{"key":"10.1016\/j.cardfail.2024.08.044_bib0003","doi-asserted-by":"crossref","first-page":"1242","DOI":"10.1002\/ejhf.890","article-title":"Investigators ESCHFL-TR. Clinical phenotypes and outcome of patients hospitalized for acute heart failure: the ESC Heart Failure Long-Term Registry","volume":"19","author":"Chioncel","year":"2017","journal-title":"Eur J Heart Fail"},{"key":"10.1016\/j.cardfail.2024.08.044_bib0004","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/j.jacc.2012.09.038","article-title":"Rehospitalization for heart failure: problems and perspectives","volume":"61","author":"Gheorghiade","year":"2013","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.cardfail.2024.08.044_bib0005","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1016\/j.cardfail.2014.03.006","article-title":"Insufficient natriuretic response to continuous intravenous furosemide is associated with poor long-term outcomes in acute decompensated heart failure","volume":"20","author":"Singh","year":"2014","journal-title":"J Card Fail"},{"key":"10.1016\/j.cardfail.2024.08.044_bib0006","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1007\/s11897-019-00444-z","article-title":"Utility of urine biomarkers and electrolytes for the management of heart failure","volume":"16","author":"Verbrugge","year":"2019","journal-title":"Curr Heart Fail Rep"},{"key":"10.1016\/j.cardfail.2024.08.044_bib0007","doi-asserted-by":"crossref","first-page":"3599","DOI":"10.1093\/eurheartj\/ehab368","article-title":"2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure","volume":"42","author":"McDonagh","year":"2021","journal-title":"Eur Heart J"},{"key":"10.1016\/j.cardfail.2024.08.044_bib0008","doi-asserted-by":"crossref","first-page":"2625","DOI":"10.1038\/s41591-023-02532-z","article-title":"Natriuresis-guided diuretic therapy in acute heart failure: a pragmatic randomized trial","volume":"29","author":"Ter Maaten","year":"2023","journal-title":"Nat Med"},{"key":"10.1016\/j.cardfail.2024.08.044_bib0009","article-title":"Protocolized natriuresis-guided decongestion improves diuretic response: the multicenter ENACT-HF study","volume":"17","author":"Dauw","year":"2024","journal-title":"Circ Heart Fail"},{"key":"10.1016\/j.cardfail.2024.08.044_bib0010","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1161\/CIRCHEARTFAILURE.114.001377","article-title":"Urinary composition during decongestive treatment in heart failure with reduced ejection fraction","volume":"7","author":"Verbrugge","year":"2014","journal-title":"Circ Heart Fail"},{"key":"10.1016\/j.cardfail.2024.08.044_bib0011","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1080\/AC.71.3.3152090","article-title":"Subclinical volume overload in stable outpatients with chronic heart failure","volume":"71","author":"Boonen","year":"2016","journal-title":"Acta Cardiol"},{"key":"10.1016\/j.cardfail.2024.08.044_bib0012","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1056\/NEJMoa2203094","article-title":"Acetazolamide in acute decompensated heart failure with volume overload","volume":"387","author":"Mullens","year":"2022","journal-title":"N Engl J Med"},{"key":"10.1016\/j.cardfail.2024.08.044_bib0013","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1093\/eurheartj\/ehac689","article-title":"Combining loop with thiazide diuretics for decompensated heart failure: the CLOROTIC trial","volume":"44","author":"Trullas","year":"2023","journal-title":"Eur Heart J"},{"key":"10.1016\/j.cardfail.2024.08.044_bib0014","doi-asserted-by":"crossref","first-page":"1995","DOI":"10.1093\/eurheartj\/ehad236","article-title":"Pre-treatment bicarbonate levels and decongestion by acetazolamide: the ADVOR trial","volume":"44","author":"Martens","year":"2023","journal-title":"Eur Heart J"},{"key":"10.1016\/j.cardfail.2024.08.044_bib0015","doi-asserted-by":"crossref","first-page":"950","DOI":"10.1001\/jamacardio.2017.2198","article-title":"Efficacy and Safety of Spironolactone in Acute Heart Failure: the ATHENA-HF randomized clinical trial","volume":"2","author":"Butler","year":"2017","journal-title":"JAMA Cardiol"},{"key":"10.1016\/j.cardfail.2024.08.044_bib0016","doi-asserted-by":"crossref","first-page":"1451","DOI":"10.1002\/ejhf.1802","article-title":"Spironolactone metabolite concentrations in decompensated heart failure: insights from the ATHENA-HF trial","volume":"22","author":"de Denus","year":"2020","journal-title":"Eur J Heart Fail"},{"key":"10.1016\/j.cardfail.2024.08.044_bib0017","doi-asserted-by":"crossref","first-page":"1341","DOI":"10.1002\/(SICI)1097-0258(19990615)18:11<1341::AID-SIM129>3.0.CO;2-7","article-title":"Combining mortality and longitudinal measures in clinical trials","volume":"18","author":"Finkelstein","year":"1999","journal-title":"Stat Med"},{"key":"10.1016\/j.cardfail.2024.08.044_bib0018","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1378\/chest.07-2331","article-title":"Does central venous pressure predict fluid responsiveness? A systematic review of the literature and the tale of seven mares","volume":"134","author":"Marik","year":"2008","journal-title":"Chest"},{"key":"10.1016\/j.cardfail.2024.08.044_bib0019","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1093\/eurjhf\/hft036","article-title":"Fluid loss, venous congestion, and worsening renal function in acute decompensated heart failure","volume":"15","author":"Aronson","year":"2013","journal-title":"Eur J Heart Fail"},{"key":"10.1016\/j.cardfail.2024.08.044_bib0020","doi-asserted-by":"crossref","first-page":"1386","DOI":"10.1016\/j.jacc.2024.02.020","article-title":"Water conservation overrides osmotic diuresis during SGLT2 inhibition in patients with heart failure","volume":"83","author":"Marton","year":"2024","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.cardfail.2024.08.044_bib0021","doi-asserted-by":"crossref","first-page":"1319","DOI":"10.1001\/jama.297.12.1319","article-title":"Effects of oral tolvaptan in patients hospitalized for worsening heart failure: the EVEREST Outcome trial","volume":"297","author":"Konstam","year":"2007","journal-title":"JAMA"},{"key":"10.1016\/j.cardfail.2024.08.044_bib0022","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/j.jchf.2019.01.007","article-title":"Natriuretic response is highly variable and associated with 6-month survival: insights from the ROSE-AHF trial","volume":"7","author":"Hodson","year":"2019","journal-title":"JACC Heart Fail"},{"key":"10.1016\/j.cardfail.2024.08.044_bib0023","doi-asserted-by":"crossref","first-page":"2013","DOI":"10.1016\/j.jacc.2023.03.400","article-title":"Natriuretic response to acetazolamide in patients with acute heart failure and volume overload","volume":"81","author":"Verbrugge","year":"2023","journal-title":"J Am Coll Cardiol"}],"container-title":["Journal of Cardiac Failure"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1071916424003609?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1071916424003609?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T17:21:38Z","timestamp":1762363298000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1071916424003609"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4]]},"references-count":23,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,4]]}},"alternative-id":["S1071916424003609"],"URL":"https:\/\/doi.org\/10.1016\/j.cardfail.2024.08.044","relation":{},"ISSN":["1071-9164"],"issn-type":[{"value":"1071-9164","type":"print"}],"subject":[],"published":{"date-parts":[[2025,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Rationale and Design of the DECONGEST (Diuretic Treatment in Acute Heart Failure With Volume Overload Guided by Serial Spot Urine Sodium Assessment) Study","name":"articletitle","label":"Article Title"},{"value":"Journal of Cardiac Failure","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cardfail.2024.08.044","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}