{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T15:43:50Z","timestamp":1777477430986,"version":"3.51.4"},"reference-count":15,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2009,10,1]],"date-time":"2009-10-01T00:00:00Z","timestamp":1254355200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Can Assoc Radiol J"],"published-print":{"date-parts":[[2009,10]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To review the association of an abnormal prenatal sonogram with most recent serum creatinine in patients with proven posterior urethral valves (PUV).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Since 1992, all live-born patients between 1992\u20132004 with clinically proven PUV, with postnatally proven PUV, from 2 pediatric tertiary care centers, were reviewed for age at diagnosis, most recent serum creatinine, presence of chronic renal failure (CRF) (serum creatinine &gt;2 standard deviations above normal for age), or end stage renal disease (dialysis or transplant). Available antenatal reports from the 2 centres and surrounding community hospitals were reviewed for gestational age (GA) at the time of ultrasound, volume of amniotic fluid, and urinary-tract abnormality.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Thirty-four patients with proven PUV and prenatal sonograms were identified (1992\u20132004). Eighteen patients had abnormalities on their prenatal sonogram, with poor outcome in 5 (mean follow-up, 8 years [1\u201313 y]). No specific features were identified on prenatal sonogram. Sixteen patients had normal prenatal sonograms, with poor outcomes in 2 (mean follow-up, 8 years [3\u201313y]). There is an increased risk of an abnormal serum creatinine among those patients with an abnormal prenatal study, odds ratio (OR) 2.6 (95% confidence interval, 0.35\u201332).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>PUV represents a spectrum of disease severity. A normal prenatal ultrasound does not preclude PUV. The majority of patients with a normal prenatal examination have good outcomes. The OR suggests that there may be increased risk for poor outcome in those with an abnormal prenatal examination. A multicenter study is necessary to obtain a larger sample size and more precise ORs.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1016\/j.carj.2009.06.003","type":"journal-article","created":{"date-parts":[[2009,7,25]],"date-time":"2009-07-25T13:08:37Z","timestamp":1248527317000},"page":"185-189","source":"Crossref","is-referenced-by-count":6,"title":["Abnormal Antenatal Sonogram: An Indicator of Disease Severity in Children with Posterior Urethral Valves"],"prefix":"10.1177","volume":"60","author":[{"given":"Sarah","family":"Harvie","sequence":"first","affiliation":[{"name":"Department of Radiology, Peterborough Health Centre, Ontario, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lynne","family":"McLeod","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, IWK Health Centre, Halifax, Nova Scotia, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philip","family":"Acott","sequence":"additional","affiliation":[{"name":"Department of Nephrology, IWK Health Centre, Halifax, Nova Scotia, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eilish","family":"Walsh","sequence":"additional","affiliation":[{"name":"Department of Radiology, Dr Charles A. Janeway Children's Health Centre, St John's, Newfoundland, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamed","family":"Abdolell","sequence":"additional","affiliation":[{"name":"Department of Radiology, QE II Health Sciences Centre, Halifax, Nova Scotia, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marian B.","family":"Macken","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Imaging, IWK Health Centre, Halifax, Nova Scotia, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2009,10,1]]},"reference":[{"key":"bibr1-j.carj.2009.06.003","doi-asserted-by":"publisher","DOI":"10.1016\/S0090-4295(02)01621-7"},{"key":"bibr2-j.carj.2009.06.003","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)32684-8"},{"key":"bibr3-j.carj.2009.06.003","first-page":"2210","volume":"11","author":"Warren J.","year":"2004","journal-title":"Canadian J Urol"},{"key":"bibr4-j.carj.2009.06.003","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.1993.tb00734.x"},{"key":"bibr5-j.carj.2009.06.003","doi-asserted-by":"publisher","DOI":"10.1055\/s-2008-1072270"},{"key":"bibr6-j.carj.2009.06.003","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)39695-7"},{"key":"bibr7-j.carj.2009.06.003","doi-asserted-by":"publisher","DOI":"10.1159\/000020834"},{"key":"bibr8-j.carj.2009.06.003","doi-asserted-by":"publisher","DOI":"10.1159\/000081586"},{"key":"bibr9-j.carj.2009.06.003","doi-asserted-by":"publisher","DOI":"10.1007\/s00383-002-0877-1"},{"key":"bibr10-j.carj.2009.06.003","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)36532-1"},{"key":"bibr11-j.carj.2009.06.003","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.1993.tb16277.x"},{"key":"bibr12-j.carj.2009.06.003","doi-asserted-by":"publisher","DOI":"10.1097\/00005392-199909010-00076"},{"key":"bibr13-j.carj.2009.06.003","doi-asserted-by":"publisher","DOI":"10.1007\/s00467-004-1474-4"},{"key":"bibr14-j.carj.2009.06.003","doi-asserted-by":"publisher","DOI":"10.1046\/j.1464-410X.2003.04178.x"},{"key":"bibr15-j.carj.2009.06.003","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.1988.tb04267.x"}],"container-title":["Canadian Association of Radiologists Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0846537109001132?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0846537109001132?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1016\/j.carj.2009.06.003","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1016\/j.carj.2009.06.003","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1016\/j.carj.2009.06.003","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T13:58:31Z","timestamp":1777384711000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1016\/j.carj.2009.06.003"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,10]]},"references-count":15,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2009,10]]}},"alternative-id":["10.1016\/j.carj.2009.06.003"],"URL":"https:\/\/doi.org\/10.1016\/j.carj.2009.06.003","relation":{},"ISSN":["0846-5371","1488-2361"],"issn-type":[{"value":"0846-5371","type":"print"},{"value":"1488-2361","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,10]]}}}