{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T05:07:20Z","timestamp":1778908040151,"version":"3.51.4"},"reference-count":15,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2017,2,1]],"date-time":"2017-02-01T00:00:00Z","timestamp":1485907200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Can Assoc Radiol J"],"published-print":{"date-parts":[[2017,2]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>The study sought to assess the frequency and prognostic value of hyperattenuating adrenal glands on contrast-enhanced computed tomography (CT) scans of surgical intensive care unit (ICU) patients with acute clinical deterioration.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Eighty-eight consecutive ICU patients (63.2 \u00b1 14.5 years of age) were included in this retrospective analysis. All patients underwent biphasic contrast-enhanced CT due to an acute clinical deterioration. Hyperattenuation of the adrenal glands was assessed subjectively and objectively. Subjective presence or absence of hyperattenuating adrenal glands was assessed by 2 blinded radiologists (J.B. and R.S.L.) in consensus. Hounsfield units (HU) were measured in the adrenal glands and in the inferior vena cava. Objective hyperattenuation was defined as HU (adrenal glands) &gt; HU (inferior vena cava) with a 15-HU threshold. Death within 14 days following CT was set as endpoint and acquired from electronic patient data.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Thirty-eight patients (43.2%, Group A\n                      <jats:sub>subj<\/jats:sub>\n                      ) exhibited hyperattenuation of the adrenal glands, whereas 50 patients (56.8%, Group B\n                      <jats:sub>subj<\/jats:sub>\n                      ) did not. Concerning the objective analysis, 31 patients (35.2%, Group A\n                      <jats:sub>obj<\/jats:sub>\n                      ) exhibited hyperdense adrenal glands, whereas 53 patients (64.8%, Group B\n                      <jats:sub>obj<\/jats:sub>\n                      ) did not. Overall 27 of 88 patients (30.6%) died within 14 days following the CT examination. Lethal outcome was significantly more frequent among patients in Group A\n                      <jats:sub>subj<\/jats:sub>\n                      and A\n                      <jats:sub>obj<\/jats:sub>\n                      (19 of 38 patients [50.0%] and 15 of 31 patients [48.4%]) as compared with patients in Group B\n                      <jats:sub>subj<\/jats:sub>\n                      (8 of 50 patients [16.0%]) and Group B\n                      <jats:sub>obj<\/jats:sub>\n                      (12 of 57 patients [21.1%]; P &lt; .05). Subjective and objective analysis correlated significantly ( P &lt; .05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Hyperattenuation of adrenal glands on contrast-enhanced CT of ICU patients with acute clinical deterioration is associated with a high mortality and might serve as a prognostic marker for patients' outcome.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1016\/j.carj.2016.07.006","type":"journal-article","created":{"date-parts":[[2016,12,20]],"date-time":"2016-12-20T18:17:47Z","timestamp":1482257867000},"page":"21-26","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":13,"title":["Contrast-Enhanced Computed Tomography in Intensive Care Unit Patients with Acute Clinical Deterioration: Impact of Hyperattenuating Adrenal Glands"],"prefix":"10.1177","volume":"68","author":[{"given":"Johannes","family":"Boos","sequence":"first","affiliation":[{"name":"Medical Faculty, Department of Diagnostic and Interventional Radiology, University Dusseldorf, Moorenstrasse 5, 40225, Dusseldorf, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julia","family":"Schek","sequence":"additional","affiliation":[{"name":"Radiologie, MVZ am RKK, Bremen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patric","family":"Kr\u00f6pil","sequence":"additional","affiliation":[{"name":"Medical Faculty, Department of Diagnostic and Interventional Radiology, University Dusseldorf, Moorenstrasse 5, 40225, Dusseldorf, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philipp","family":"Heusch","sequence":"additional","affiliation":[{"name":"Medical Faculty, Department of Diagnostic and Interventional Radiology, University Dusseldorf, Moorenstrasse 5, 40225, Dusseldorf, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Niklas","family":"Heinzler","sequence":"additional","affiliation":[{"name":"Medical Faculty, Department of Diagnostic and Interventional Radiology, University Dusseldorf, Moorenstrasse 5, 40225, Dusseldorf, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gerald","family":"Antoch","sequence":"additional","affiliation":[{"name":"Medical Faculty, Department of Diagnostic and Interventional Radiology, University Dusseldorf, Moorenstrasse 5, 40225, Dusseldorf, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rotem Shlomo","family":"Lanzman","sequence":"additional","affiliation":[{"name":"Medical Faculty, Department of Diagnostic and Interventional Radiology, University Dusseldorf, Moorenstrasse 5, 40225, Dusseldorf, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2017,2,1]]},"reference":[{"key":"bibr1-j.carj.2016.07.006","doi-asserted-by":"publisher","DOI":"10.1007\/s10140-012-1063-y"},{"key":"bibr2-j.carj.2016.07.006","doi-asserted-by":"publisher","DOI":"10.1007\/s10140-007-0676-z"},{"key":"bibr3-j.carj.2016.07.006","doi-asserted-by":"publisher","DOI":"10.1016\/S0009-9260(02)00522-6"},{"key":"bibr4-j.carj.2016.07.006","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.173.4.10511165"},{"key":"bibr5-j.carj.2016.07.006","doi-asserted-by":"publisher","DOI":"10.1097\/RCT.0b013e31828b690d"},{"key":"bibr6-j.carj.2016.07.006","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-013-3050-4"},{"key":"bibr7-j.carj.2016.07.006","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.08.1474"},{"key":"bibr8-j.carj.2016.07.006","doi-asserted-by":"publisher","DOI":"10.1097\/RCT.0b013e3181d53276"},{"key":"bibr9-j.carj.2016.07.006","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.164.2.3602389"},{"key":"bibr10-j.carj.2016.07.006","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.163.6.7992732"},{"key":"bibr11-j.carj.2016.07.006","doi-asserted-by":"publisher","DOI":"10.1016\/j.crad.2004.02.012"},{"key":"bibr12-j.carj.2016.07.006","doi-asserted-by":"publisher","DOI":"10.1016\/j.carj.2013.03.002"},{"key":"bibr13-j.carj.2016.07.006","doi-asserted-by":"publisher","DOI":"10.1097\/TA.0b013e3182827270"},{"key":"bibr14-j.carj.2016.07.006","doi-asserted-by":"publisher","DOI":"10.1016\/j.jemermed.2013.04.036"},{"key":"bibr15-j.carj.2016.07.006","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.10.5736"}],"container-title":["Canadian Association of Radiologists Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0846537116300948?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0846537116300948?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/journals.sagepub.com\/doi\/pdf\/10.1016\/j.carj.2016.07.006","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/journals.sagepub.com\/doi\/full-xml\/10.1016\/j.carj.2016.07.006","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/journals.sagepub.com\/doi\/pdf\/10.1016\/j.carj.2016.07.006","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T13:55:35Z","timestamp":1777384535000},"score":1,"resource":{"primary":{"URL":"http:\/\/journals.sagepub.com\/doi\/10.1016\/j.carj.2016.07.006"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,2]]},"references-count":15,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,2]]}},"alternative-id":["10.1016\/j.carj.2016.07.006"],"URL":"https:\/\/doi.org\/10.1016\/j.carj.2016.07.006","relation":{},"ISSN":["0846-5371","1488-2361"],"issn-type":[{"value":"0846-5371","type":"print"},{"value":"1488-2361","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,2]]}}}