{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T02:44:03Z","timestamp":1773888243543,"version":"3.50.1"},"reference-count":33,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2007,5,1]],"date-time":"2007-05-01T00:00:00Z","timestamp":1177977600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiovascular Pathology"],"published-print":{"date-parts":[[2007,5]]},"DOI":"10.1016\/j.carpath.2006.10.004","type":"journal-article","created":{"date-parts":[[2007,5,15]],"date-time":"2007-05-15T09:30:47Z","timestamp":1179221447000},"page":"171-178","source":"Crossref","is-referenced-by-count":20,"title":["Role of inflammation in nonrheumatic, regurgitant heart valve disease. A comparative, descriptive study regarding apolipoproteins and inflammatory cells in nonrheumatic heart valve disease"],"prefix":"10.1016","volume":"16","author":[{"given":"Wallby","family":"Lars","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steffensen","family":"Thora","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Broqvist","family":"Mats","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"24","key":"10.1016\/j.carpath.2006.10.004_bib1","doi-asserted-by":"crossref","first-page":"3316","DOI":"10.1161\/CIRCULATIONAHA.104.486738","article-title":"Spectrum of calcific aortic valve disease: pathogenesis, disease progression, and treatment strategies","volume":"111","author":"Freeman","year":"2005","journal-title":"Circulation"},{"issue":"5","key":"10.1016\/j.carpath.2006.10.004_bib2","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1016\/j.ahj.2003.12.014","article-title":"Aortic stenosis and hyperlipidemia: establishing a cause\u2013effect relationship","volume":"147","author":"Otto","year":"2004","journal-title":"Am Heart J"},{"issue":"10","key":"10.1016\/j.carpath.2006.10.004_bib3","doi-asserted-by":"crossref","first-page":"1180","DOI":"10.1161\/01.CIR.0000140722.85490.EA","article-title":"Targeted therapy to prevent progression of calcific aortic stenosis","volume":"110","author":"Rajamannan","year":"2004","journal-title":"Circulation"},{"issue":"23","key":"10.1016\/j.carpath.2006.10.004_bib4","doi-asserted-by":"crossref","first-page":"2441","DOI":"10.1056\/NEJMe058070","article-title":"Statins for aortic stenosis","volume":"352","author":"Rosenhek","year":"2005","journal-title":"N Engl J Med"},{"issue":"2","key":"10.1016\/j.carpath.2006.10.004_bib5","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1161\/01.CIR.90.2.844","article-title":"Characterization of the early lesions of \u2018degenerative\u2019 valvular aortic stenosis","volume":"90","author":"Otto","year":"1994","journal-title":"Circulation"},{"issue":"5","key":"10.1016\/j.carpath.2006.10.004_bib6","doi-asserted-by":"crossref","first-page":"1162","DOI":"10.1016\/0735-1097(94)90606-8","article-title":"Accumulation of T lymphocytes and expression of interleukin-2 receptors in nonrheumatic stenotic aortic valves","volume":"23","author":"Olsson","year":"1994","journal-title":"J Am Coll Cardiol"},{"issue":"5","key":"10.1016\/j.carpath.2006.10.004_bib7","doi-asserted-by":"crossref","first-page":"1218","DOI":"10.1161\/01.ATV.19.5.1218","article-title":"Presence of oxidized low density lipoprotein in nonrheumatic stenotic aortic valves","volume":"19","author":"Olsson","year":"1999","journal-title":"Arterioscler Thromb Vasc Biol"},{"issue":"4","key":"10.1016\/j.carpath.2006.10.004_bib8","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1161\/01.ATV.16.4.523","article-title":"Apolipoproteins B, (a), and E accumulate in the morphologically early lesion of \u2018degenerative\u2019 valvular aortic stenosis","volume":"16","author":"O'Brien","year":"1996","journal-title":"Arterioscler Thromb Vasc Biol"},{"issue":"8","key":"10.1016\/j.carpath.2006.10.004_bib9","doi-asserted-by":"crossref","first-page":"2163","DOI":"10.1161\/01.CIR.92.8.2163","article-title":"Osteopontin is expressed in human aortic valvular lesions","volume":"92","author":"O'Brien","year":"1995","journal-title":"Circulation"},{"issue":"11","key":"10.1016\/j.carpath.2006.10.004_bib10","doi-asserted-by":"crossref","first-page":"1522","DOI":"10.1161\/01.CIR.103.11.1522","article-title":"Bone formation and inflammation in cardiac valves","volume":"103","author":"Mohler","year":"2001","journal-title":"Circulation"},{"issue":"4","key":"10.1016\/j.carpath.2006.10.004_bib11","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1136\/heart.88.4.321","article-title":"Calcification of bicuspid aortic valves","volume":"88","author":"Otto","year":"2002","journal-title":"Heart"},{"issue":"4","key":"10.1016\/j.carpath.2006.10.004_bib12","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1136\/heart.88.4.348","article-title":"T Lymphocyte infiltration in non-rheumatic aortic stenosis: a comparative descriptive study between tricuspid and bicuspid aortic valves","volume":"88","author":"Wallby","year":"2002","journal-title":"Heart"},{"issue":"2","key":"10.1016\/j.carpath.2006.10.004_bib13","first-page":"101","article-title":"Postinflammatory scarring of cardiac valves of rheumatic and nonrheumatic etiology","volume":"3","author":"Gallo","year":"1990","journal-title":"Am J Cardiovasc Pathol"},{"issue":"6","key":"10.1016\/j.carpath.2006.10.004_bib14","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1016\/S0046-8177(87)80355-6","article-title":"Surgical pathology of removed natural and prosthetic heart valves","volume":"18","author":"Schoen","year":"1987","journal-title":"Hum Pathol"},{"issue":"10","key":"10.1016\/j.carpath.2006.10.004_bib15","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1016\/S0025-6196(12)62057-6","article-title":"Surgical pathology of pure aortic stenosis: a study of 374 cases","volume":"59","author":"Subramanian","year":"1984","journal-title":"Mayo Clin Proc"},{"issue":"3","key":"10.1016\/j.carpath.2006.10.004_bib16","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/0021-9150(86)90122-X","article-title":"Inflammatory infiltrates in human coronary atherosclerosis","volume":"59","author":"Stratford","year":"1986","journal-title":"Atherosclerosis"},{"issue":"3","key":"10.1016\/j.carpath.2006.10.004_bib17","doi-asserted-by":"crossref","first-page":"746","DOI":"10.1016\/S0735-1097(97)00205-2","article-title":"Optimizing timing of surgical correction in patients with severe aortic regurgitation: role of symptoms","volume":"30","author":"Klodas","year":"1997","journal-title":"J Am Coll Cardiol"},{"issue":"5","key":"10.1016\/j.carpath.2006.10.004_bib18","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1016\/S1010-7940(03)00502-5","article-title":"Mortality after mitral regurgitation surgery: importance of clinical and echocardiographic variables","volume":"24","author":"Bech-Hanssen","year":"2003","journal-title":"Eur J Cardiothorac Surg"},{"issue":"1","key":"10.1016\/j.carpath.2006.10.004_bib19","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/S1010-7940(98)00268-1","article-title":"Gender differences in patients with severe aortic stenosis: impact on preoperative left ventricular geometry and function, as well as early postoperative morbidity and mortality","volume":"15","author":"Bech-Hanssen","year":"1999","journal-title":"Eur J Cardiothorac Surg"},{"issue":"9229","key":"10.1016\/j.carpath.2006.10.004_bib20","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1016\/S0140-6736(00)02572-1","article-title":"Are atherosclerotic processes involved in aortic-valve calcification?","volume":"356","author":"Mohler","year":"2000","journal-title":"Lancet"},{"issue":"6","key":"10.1016\/j.carpath.2006.10.004_bib21","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1016\/S0002-9149(01)01821-5","article-title":"Association of coronary risk factors and use of statins with progression of mild valvular aortic stenosis in older persons","volume":"88","author":"Aronow","year":"2001","journal-title":"Am J Cardiol"},{"issue":"16","key":"10.1016\/j.carpath.2006.10.004_bib22","doi-asserted-by":"crossref","first-page":"1927","DOI":"10.1161\/hc4101.097527","article-title":"Progression of aortic valve calcification: association with coronary atherosclerosis and cardiovascular risk factors","volume":"104","author":"Pohle","year":"2001","journal-title":"Circulation"},{"issue":"22","key":"10.1016\/j.carpath.2006.10.004_bib23","doi-asserted-by":"crossref","first-page":"2660","DOI":"10.1161\/01.CIR.0000017435.87463.72","article-title":"Atorvastatin inhibits hypercholesterolemia-induced cellular proliferation and bone matrix production in the rabbit aortic valve","volume":"105","author":"Rajamannan","year":"2002","journal-title":"Circulation"},{"issue":"5","key":"10.1016\/j.carpath.2006.10.004_bib24","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1016\/j.ahj.2003.11.011","article-title":"Lipid profile of patients with aortic stenosis might be predictive of rate of progression","volume":"147","author":"Yilmaz","year":"2004","journal-title":"Am Heart J"},{"issue":"7","key":"10.1016\/j.carpath.2006.10.004_bib25","doi-asserted-by":"crossref","first-page":"920","DOI":"10.1161\/01.CIR.0000155623.48408.C5","article-title":"Frequency by decades of unicuspid, bicuspid, and tricuspid aortic valves in adults having isolated aortic valve replacement for aortic stenosis, with or without associated aortic regurgitation","volume":"111","author":"Roberts","year":"2005","journal-title":"Circulation"},{"issue":"9298","key":"10.1016\/j.carpath.2006.10.004_bib26","doi-asserted-by":"crossref","first-page":"2026","DOI":"10.1016\/S0140-6736(01)07098-2","article-title":"High apolipoprotein B, low apolipoprotein A-I, and improvement in the prediction of fatal myocardial infarction (AMORIS study): a prospective study","volume":"358","author":"Walldius","year":"2001","journal-title":"Lancet"},{"issue":"2","key":"10.1016\/j.carpath.2006.10.004_bib27","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1046\/j.1365-2796.2002.00937.x","article-title":"Serum lipids, lipoprotein(a) level, and apolipoprotein(a) isoforms as prognostic markers in patients with coronary heart disease","volume":"251","author":"Lundstam","year":"2002","journal-title":"J Intern Med"},{"issue":"8","key":"10.1016\/j.carpath.2006.10.004_bib28","first-page":"1701","article-title":"Lipid profiles in untreated patients with rheumatoid arthritis","volume":"26","author":"Park","year":"1999","journal-title":"J Rheumatol"},{"issue":"2","key":"10.1016\/j.carpath.2006.10.004_bib29","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1002\/elps.1150190234","article-title":"Analysis of changes in acute-phase plasma proteins in an acute inflammatory response and in rheumatoid arthritis using two-dimensional gel electrophoresis","volume":"19","author":"Doherty","year":"1998","journal-title":"Electrophoresis"},{"issue":"2","key":"10.1016\/j.carpath.2006.10.004_bib30","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/S0009-9120(88)80094-8","article-title":"Serum total, HDL, LDL cholesterol, and triglyceride levels in patients with rheumatoid arthritis","volume":"21","author":"Lakatos","year":"1988","journal-title":"Clin Biochem"},{"issue":"7","key":"10.1016\/j.carpath.2006.10.004_bib31","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1016\/0026-0495(93)90050-X","article-title":"Apolipoproteins A-I and B and cholesterol in synovial fluid of patients with rheumatoid arthritis","volume":"42","author":"Ananth","year":"1993","journal-title":"Metabolism"},{"issue":"8","key":"10.1016\/j.carpath.2006.10.004_bib32","doi-asserted-by":"crossref","first-page":"2381","DOI":"10.1182\/blood.V97.8.2381","article-title":"Apolipoprotein A-I inhibits the production of interleukin-1beta and tumor necrosis factor-alpha by blocking contact-mediated activation of monocytes by T lymphocytes","volume":"97","author":"Hyka","year":"2001","journal-title":"Blood"},{"issue":"1\u20132","key":"10.1016\/j.carpath.2006.10.004_bib33","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/S1568-9972(01)00018-0","article-title":"High-density lipoprotein-associated apolipoprotein A-I: the missing link between infection and chronic inflammation?","volume":"1","author":"Burger","year":"2002","journal-title":"Autoimmun Rev"}],"container-title":["Cardiovascular Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1054880707000166?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1054880707000166?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,1,7]],"date-time":"2019-01-07T12:28:33Z","timestamp":1546864113000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1054880707000166"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,5]]},"references-count":33,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2007,5]]}},"alternative-id":["S1054880707000166"],"URL":"https:\/\/doi.org\/10.1016\/j.carpath.2006.10.004","relation":{},"ISSN":["1054-8807"],"issn-type":[{"value":"1054-8807","type":"print"}],"subject":[],"published":{"date-parts":[[2007,5]]}}}