{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T16:45:49Z","timestamp":1791045949045,"version":"4.1.0"},"reference-count":44,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2009,5,1]],"date-time":"2009-05-01T00:00:00Z","timestamp":1241136000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiovascular Pathology"],"published-print":{"date-parts":[[2009,5]]},"DOI":"10.1016\/j.carpath.2007.12.013","type":"journal-article","created":{"date-parts":[[2008,3,7]],"date-time":"2008-03-07T00:07:13Z","timestamp":1204848433000},"page":"156-166","source":"Crossref","is-referenced-by-count":36,"title":["Cardiac oxidative stress and remodeling following infarction: role of NADPH oxidase"],"prefix":"10.1016","volume":"18","author":[{"given":"Wenyuan","family":"Zhao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dawn","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ran","family":"Yan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yao","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.carpath.2007.12.013_bib1","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1161\/01.RES.68.3.856","article-title":"Cellular basis of chronic ventricular remodeling after myocardial infarction in rats","volume":"68","author":"Olivetti","year":"1991","journal-title":"Circ Res"},{"key":"10.1016\/j.carpath.2007.12.013_bib2","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.1161\/01.CIR.0000085658.98621.49","article-title":"Ventricular remodeling after infarction and the extracellular collagen matrix: when is enough?","volume":"108","author":"Jugdutt","year":"2003","journal-title":"Circulation"},{"key":"10.1016\/j.carpath.2007.12.013_bib3","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.cardiores.2005.01.011","article-title":"Healing after myocardial infarction","volume":"66","author":"Ertl","year":"2005","journal-title":"Cardiovasc Res"},{"key":"10.1016\/j.carpath.2007.12.013_bib4","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1093\/cvr\/27.2.145","article-title":"Ischemic myocardial injury and ventricular remodeling","volume":"27","author":"Anversa","year":"1993","journal-title":"Cardiovasc Res"},{"key":"10.1016\/j.carpath.2007.12.013_bib5","doi-asserted-by":"crossref","first-page":"11A","DOI":"10.1016\/S0002-9149(99)80378-6","article-title":"Pathophysiologic aspects of end-stage heart failure","volume":"75","author":"Francis","year":"1995","journal-title":"Am J Cardio"},{"key":"10.1016\/j.carpath.2007.12.013_bib6","doi-asserted-by":"crossref","first-page":"4065","DOI":"10.1161\/01.CIR.96.11.4065","article-title":"Extracellular matrix remodeling in heart failure","volume":"96","author":"Weber","year":"1997","journal-title":"Circulation"},{"key":"10.1016\/j.carpath.2007.12.013_bib7","first-page":"291","article-title":"Antioxidant and oxidative stress changes during heart failure subsequent to myocardial infarction in rats","volume":"148","author":"Hill","year":"1996","journal-title":"Am J Pathol"},{"key":"10.1016\/j.carpath.2007.12.013_bib8","doi-asserted-by":"crossref","first-page":"1200","DOI":"10.1006\/bbrc.2001.4493","article-title":"Expression of p22-phox and gp91-phox, essential components of NADPH oxidase, increases after myocardial infarction","volume":"281","author":"Fukui","year":"2001","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.carpath.2007.12.013_bib9","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1016\/j.bbrc.2004.10.106","article-title":"Oxidative stress in the infarcted heart: role of de novo angiotensin II production","volume":"325","author":"Lu","year":"2004","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.carpath.2007.12.013_bib10","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1536\/ihj.37.177","article-title":"Decreased glutathione levels in acute myocardial infarction","volume":"37","author":"Usal","year":"1996","journal-title":"Jpn Heart J"},{"key":"10.1016\/j.carpath.2007.12.013_bib11","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1023\/A:1025448908694","article-title":"Antioxidant enzyme gene expression in congestive heart failure following myocardial infarction","volume":"251","author":"Khaper","year":"2003","journal-title":"Mol Cell Biochem"},{"key":"10.1016\/j.carpath.2007.12.013_bib12","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/S0735-1097(01)01709-0","article-title":"Improved post-myocardial infarction survival with probucol in rats: effects on left ventricular function, morphology, cardiac oxidative stress and cytokine expression","volume":"39","author":"Sia","year":"2002","journal-title":"J Am Col Cardiol"},{"key":"10.1016\/j.carpath.2007.12.013_bib13","doi-asserted-by":"crossref","first-page":"2549","DOI":"10.1161\/01.CIR.0000016721.84535.00","article-title":"Beneficial effects of long-term use of the antioxidant probucol in heart failure in the rat","volume":"105","author":"Sia","year":"2002","journal-title":"Circulation"},{"key":"10.1016\/j.carpath.2007.12.013_bib14","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1161\/01.RES.87.5.392","article-title":"Treatment with dimethylthiourea prevents left ventricular remodeling and failure after experimental myocardial infarction in mice: role of oxidative stress","volume":"87","author":"Kinugawa","year":"2000","journal-title":"Circ Res"},{"key":"10.1016\/j.carpath.2007.12.013_bib15","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1161\/res.89.3.198","article-title":"Oxidative stress and apoptosis in heart failure progression","volume":"89","author":"Hare","year":"2001","journal-title":"Circ Res"},{"key":"10.1016\/j.carpath.2007.12.013_bib16","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/S0891-5849(96)00327-9","article-title":"Oxidative damage and fibrogenesis","volume":"22","author":"Poli","year":"1997","journal-title":"Free Radical Biol Med"},{"key":"10.1016\/j.carpath.2007.12.013_bib17","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1111\/j.1749-6632.2002.tb04691.x","article-title":"Redox signaling through NADPH oxidases: involvement in vascular proliferation and coagulation","volume":"973","author":"Gorlach","year":"2002","journal-title":"Ann N Y Acad Sci"},{"key":"10.1016\/j.carpath.2007.12.013_bib18","doi-asserted-by":"crossref","first-page":"C1212","DOI":"10.1152\/ajpcell.00496.2001","article-title":"A NAD(P)H oxidase regulates growth and transcription in melanoma cells","volume":"282","author":"Brar","year":"2002","journal-title":"Am J Physiol Cell Physiol"},{"key":"10.1016\/j.carpath.2007.12.013_bib19","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1016\/S0022-2828(03)00145-7","article-title":"NADPH oxidase-derived superoxide anion mediates angiotensin II-induced cardiac hypertrophy","volume":"35","author":"Nakagami","year":"2003","journal-title":"J Mol Cell Cardiol"},{"key":"10.1016\/j.carpath.2007.12.013_bib20","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1161\/01.CIR.96.2.614","article-title":"Lactate and PO2 modulate superoxide anion production in bovine cardiac myocytes: potential role of NADH oxidase","volume":"15","author":"Mohazzab-H","year":"1997","journal-title":"Circulation"},{"key":"10.1016\/j.carpath.2007.12.013_bib21","doi-asserted-by":"crossref","first-page":"1559","DOI":"10.1006\/jmcc.1998.0721","article-title":"Angiotensin II, transforming growth factor-beta1 and repair in the infarcted heart","volume":"30","author":"Sun","year":"1998","journal-title":"J Mol Cell Cardiol"},{"issue":"1","key":"10.1016\/j.carpath.2007.12.013_bib22","doi-asserted-by":"crossref","first-page":"H336","DOI":"10.1152\/ajpheart.01307.2005","article-title":"ANG II-induced cardiac molecular and cellular events: role of aldosterone","volume":"291","author":"Zhao","year":"2006","journal-title":"Am J Physiol Heart Circ Physiol"},{"issue":"2","key":"10.1016\/j.carpath.2007.12.013_bib23","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1016\/j.bbrc.2004.10.064","article-title":"Temporal and spatial characteristics of apoptosis in the infarcted rat heart","volume":"325","author":"Zhao","year":"2004","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.carpath.2007.12.013_bib24","first-page":"277","article-title":"Detection of apoptosis in cardiovascular diseases","volume":"112","author":"Hunter","year":"2005","journal-title":"Methods Mol Med"},{"key":"10.1016\/j.carpath.2007.12.013_bib25","first-page":"95","article-title":"Inhibition of angiotensin-converting enzyme and attenuation of myocardial fibrosis by lisinopril in rats receiving angiotensin II","volume":"126","author":"Sun","year":"2005","journal-title":"J Lab Clin Med"},{"key":"10.1016\/j.carpath.2007.12.013_bib26","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1161\/01.RES.44.4.503","article-title":"Myocardial infarct size and ventricular function in rats","volume":"44","author":"Pfeffer","year":"1979","journal-title":"Circ Res"},{"key":"10.1016\/j.carpath.2007.12.013_bib27","doi-asserted-by":"crossref","first-page":"C1424","DOI":"10.1152\/ajpcell.1996.271.5.C1424","article-title":"Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly","volume":"271","author":"Beckman","year":"1996","journal-title":"Am J Physiol"},{"issue":"3","key":"10.1016\/j.carpath.2007.12.013_bib28","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1161\/hh1501.094115","article-title":"Oxidative stress-mediated cardiac cell death is a major determinant of ventricular dysfunction and failure in dog dilated cardiomyopathy","volume":"89","author":"Cesselli","year":"2001","journal-title":"Circ Res"},{"key":"10.1016\/j.carpath.2007.12.013_bib29","doi-asserted-by":"crossref","first-page":"2414","DOI":"10.1161\/01.CIR.96.7.2414","article-title":"Right and left myocardial antioxidant responses during heart failure subsequent to myocardial infarction","volume":"96","author":"Hill","year":"1997","journal-title":"Circulation"},{"key":"10.1016\/j.carpath.2007.12.013_bib30","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1152\/physrev.00018.2001","article-title":"Free radicals in the physiological control of cell function","volume":"82","author":"Droge","year":"2002","journal-title":"Physiol Rev"},{"key":"10.1016\/j.carpath.2007.12.013_bib31","series-title":"The molecular and cellular biology of wound repair","first-page":"391","article-title":"The role of the myofibroblast in wound healing and fibrocontractive diseases","author":"Desmouliere","year":"1996"},{"key":"10.1016\/j.carpath.2007.12.013_bib32","first-page":"469","article-title":"The tissue metalloproteinase family and the inhibitor TIMP: a study using cDNAs and recombinant proteins","volume":"49","author":"Docherty","year":"1990","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.carpath.2007.12.013_bib33","doi-asserted-by":"crossref","first-page":"1281","DOI":"10.1016\/S0022-2828(05)82390-9","article-title":"Regulation of collagen degradation in the rat myocardium after infarction","volume":"27","author":"Cleutjens","year":"1995","journal-title":"J Mol Cell Cardiol"},{"key":"10.1016\/j.carpath.2007.12.013_bib34","first-page":"86","article-title":"Apoptotic and necrotic myocyte cell deaths are independent contributing variables of infarct size in rats","volume":"74","author":"Kajstura","year":"1996","journal-title":"Lab Invest"},{"key":"10.1016\/j.carpath.2007.12.013_bib35","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1089\/152308601750100641","article-title":"Apoptosis in adriamycin cardiomyopathy and its modulation by probucol","volume":"3","author":"Kumar","year":"2001","journal-title":"Antioxid Redox Signal"},{"key":"10.1016\/j.carpath.2007.12.013_bib36","doi-asserted-by":"crossref","first-page":"2934","DOI":"10.1161\/01.CIR.99.22.2934","article-title":"Signaling pathways in reactive oxygen species-induced cardiomyocyte apoptosis","volume":"99","author":"von Harsdorf","year":"1998","journal-title":"Circulation"},{"key":"10.1016\/j.carpath.2007.12.013_bib37","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1006\/bbrc.2000.4134","article-title":"Antioxidant therapy attenuates JNK activation and apoptosis in the remote noninfarcted myocardium after large myocardial infarction","volume":"280","author":"Li","year":"2001","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.carpath.2007.12.013_bib38","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1007\/BF02859934","article-title":"Effects of carvedilol on cardiomyocyte apoptosis and gene expression in vivo after ischemia-reperfusion in rats","volume":"23","author":"Zeng","year":"2003","journal-title":"J Huazhong Univ Sci Technolog Med Sci"},{"key":"10.1016\/j.carpath.2007.12.013_bib39","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1016\/S0022-2143(03)00148-3","article-title":"Apoptosis and oxidants in the heart","volume":"142","author":"Kumar","year":"2003","journal-title":"J Lab Clin Med"},{"key":"10.1016\/j.carpath.2007.12.013_bib40","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1007\/s00395-005-0568-x","article-title":"Left ventricular remodeling after myocardial infarction in mice with targeted deletion of the NADPH oxidase subunit gp91PHOX","volume":"101","author":"Frantz","year":"2006","journal-title":"Basic Res Cardiol"},{"key":"10.1016\/j.carpath.2007.12.013_bib41","doi-asserted-by":"crossref","first-page":"894","DOI":"10.1161\/01.RES.0000261657.76299.ff","article-title":"Critical role of the NAD(P)H oxidase subunit p47phox for left ventricular remodeling\/dysfunction and survival after myocardial infarction","volume":"100","author":"Doerries","year":"2007","journal-title":"Circ Res"},{"key":"10.1016\/j.carpath.2007.12.013_bib42","doi-asserted-by":"crossref","first-page":"1168","DOI":"10.1161\/01.CIR.0000117229.60628.2F","article-title":"Pressure overload-induced myocardial hypertrophy in mice does not require gp91phox","volume":"109","author":"Maytin","year":"2004","journal-title":"Circulation"},{"key":"10.1016\/j.carpath.2007.12.013_bib43","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1016\/j.freeradbiomed.2006.11.013","article-title":"Gp91phox-containing NAD(P)H oxidase increases superoxide formation by doxorubicin and NADPH","volume":"42","author":"Deng","year":"2007","journal-title":"Fee Radic Biol Med"},{"key":"10.1016\/j.carpath.2007.12.013_bib44","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1038\/sj.bjp.0706779","article-title":"Role of reactive oxygen species and gp91phox in endothelial dysfunction of pulmonary arteries induced by chronic hypoxia","volume":"148","author":"Fresquet","year":"2006","journal-title":"Br J Pharmacol"}],"container-title":["Cardiovascular Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1054880708000045?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1054880708000045?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,5,8]],"date-time":"2019-05-08T19:19:41Z","timestamp":1557343181000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1054880708000045"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,5]]},"references-count":44,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2009,5]]}},"alternative-id":["S1054880708000045"],"URL":"https:\/\/doi.org\/10.1016\/j.carpath.2007.12.013","relation":{},"ISSN":["1054-8807"],"issn-type":[{"value":"1054-8807","type":"print"}],"subject":[],"published":{"date-parts":[[2009,5]]}}}