{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T04:08:45Z","timestamp":1790482125607,"version":"4.1.0"},"reference-count":62,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2013,7,1]],"date-time":"2013-07-01T00:00:00Z","timestamp":1372636800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiovascular Pathology"],"published-print":{"date-parts":[[2013,7]]},"DOI":"10.1016\/j.carpath.2012.11.001","type":"journal-article","created":{"date-parts":[[2012,12,22]],"date-time":"2012-12-22T07:19:01Z","timestamp":1356160741000},"page":"245-250","source":"Crossref","is-referenced-by-count":35,"title":["Emerging pathogenic mechanisms in human myxomatous mitral valve: lessons from past and novel data"],"prefix":"10.1016","volume":"22","author":[{"given":"Alexia","family":"Hulin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christophe","family":"Deroanne","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles","family":"Lambert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Olivier","family":"Defraigne","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Betty","family":"Nusgens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc","family":"Radermecker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alain","family":"Colige","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.carpath.2012.11.001_bb0005","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1093\/cvr\/cvr337","article-title":"Metallothionein-dependent up-regulation of TGF-beta2 participates in the remodelling of the myxomatous mitral valve","volume":"93","author":"Hulin","year":"2012","journal-title":"Cardiovasc Res"},{"key":"10.1016\/j.carpath.2012.11.001_bb0010","doi-asserted-by":"crossref","first-page":"2595","DOI":"10.1002\/jcp.22999","article-title":"Human myxomatous mitral valve prolapse: role of bone morphogenetic protein 4 in valvular interstitial cell activation","volume":"227","author":"Sainger","year":"2012","journal-title":"J Cell Physiol"},{"key":"10.1016\/j.carpath.2012.11.001_bb0015","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.carpath.2008.05.001","article-title":"Abundance and location of proteoglycans and hyaluronan within normal and myxomatous mitral valves","volume":"18","author":"Gupta","year":"2009","journal-title":"Cardiovasc Pathol"},{"key":"10.1016\/j.carpath.2012.11.001_bb0020","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1056\/NEJM199907013410101","article-title":"Prevalence and clinical outcome of mitral-valve prolapse","volume":"341","author":"Freed","year":"1999","journal-title":"N Engl J Med"},{"key":"10.1016\/j.carpath.2012.11.001_bb0025","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1136\/hrt.2010.205096","article-title":"Valvular heart disease: the next cardiac epidemic","volume":"97","author":"d'Arcy","year":"2011","journal-title":"Heart"},{"key":"10.1016\/j.carpath.2012.11.001_bb0030","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1007\/s12265-011-9318-7","article-title":"Cellular mechanisms in mitral valve disease","volume":"4","author":"Salhiyyah","year":"2011","journal-title":"J Cardiovasc Transl Res"},{"key":"10.1016\/j.carpath.2012.11.001_bb0035","doi-asserted-by":"crossref","first-page":"2525","DOI":"10.1161\/hc4601.099489","article-title":"Activated interstitial myofibroblasts express catabolic enzymes and mediate matrix remodeling in myxomatous heart valves","volume":"104","author":"Rabkin","year":"2001","journal-title":"Circulation"},{"key":"10.1016\/j.carpath.2012.11.001_bb0040","doi-asserted-by":"crossref","first-page":"1707","DOI":"10.1016\/j.jacc.2006.02.040","article-title":"Human degenerative valve disease is associated with up-regulation of low-density lipoprotein receptor-related protein 5 receptor-mediated bone formation","volume":"47","author":"Caira","year":"2006","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.carpath.2012.11.001_bb0045","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1038\/cr.2008.326","article-title":"TGF-beta signaling in vascular biology and dysfunction","volume":"19","author":"Goumans","year":"2009","journal-title":"Cell Res"},{"key":"10.1016\/j.carpath.2012.11.001_bb0050","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1007\/s12265-011-9314-y","article-title":"Mitral valve disease in marfan syndrome and related disorders","volume":"4","author":"Judge","year":"2011","journal-title":"J Cardiovasc Transl Res"},{"key":"10.1016\/j.carpath.2012.11.001_bb0055","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1038\/ng.199","article-title":"ADAMTSL2 mutations in geleophysic dysplasia demonstrate a role for ADAMTS-like proteins in TGF-beta bioavailability regulation","volume":"40","author":"Le Goff","year":"2008","journal-title":"Nat Genet"},{"key":"10.1016\/j.carpath.2012.11.001_bb0060","doi-asserted-by":"crossref","first-page":"R163","DOI":"10.1093\/hmg\/ddr361","article-title":"The ADAMTS(L) family and human genetic disorders","volume":"20","author":"Le Goff","year":"2011","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.carpath.2012.11.001_bb0065","doi-asserted-by":"crossref","first-page":"1586","DOI":"10.1172\/JCI200422715","article-title":"TGF-beta-dependent pathogenesis of mitral valve prolapse in a mouse model of Marfan syndrome","volume":"114","author":"Ng","year":"2004","journal-title":"J Clin Invest"},{"key":"10.1016\/j.carpath.2012.11.001_bb0070","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1126\/science.1124287","article-title":"Losartan, an AT1 antagonist, prevents aortic aneurysm in a mouse model of Marfan syndrome","volume":"312","author":"Habashi","year":"2006","journal-title":"Science"},{"key":"10.1016\/j.carpath.2012.11.001_bb0075","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.jcpa.2008.05.007","article-title":"Expression of transforming growth factor-beta1, -beta2 and -beta3 in normal and diseased canine mitral valves","volume":"139","author":"Aupperle","year":"2008","journal-title":"J Comp Pathol"},{"key":"10.1016\/j.carpath.2012.11.001_bb0080","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1080\/10408360490460933","article-title":"Latent TGF-beta binding proteins: extracellular matrix association and roles in TGF-beta activation","volume":"41","author":"Hyytiainen","year":"2004","journal-title":"Crit Rev Clin Lab Sci"},{"key":"10.1016\/j.carpath.2012.11.001_bb0085","doi-asserted-by":"crossref","first-page":"I371","DOI":"10.1161\/CIRCULATIONAHA.105.000927","article-title":"Overexpression of transforming growth factor-beta is associated with increased hyaluronan content and impairment of repair in Marfan syndrome aortic aneurysm","volume":"114","author":"Nataatmadja","year":"2006","journal-title":"Circulation"},{"key":"10.1016\/j.carpath.2012.11.001_bb0090","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1006\/dbio.2002.0731","article-title":"Temporal and distinct TGFbeta ligand requirements during mouse and avian endocardial cushion morphogenesis","volume":"248","author":"Camenisch","year":"2002","journal-title":"Dev Biol"},{"key":"10.1016\/j.carpath.2012.11.001_bb0095","doi-asserted-by":"crossref","first-page":"2659","DOI":"10.1242\/dev.124.13.2659","article-title":"TGFbeta2 knockout mice have multiple developmental defects that are non-overlapping with other TGFbeta knockout phenotypes","volume":"124","author":"Sanford","year":"1997","journal-title":"Development"},{"key":"10.1016\/j.carpath.2012.11.001_bb0100","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1002\/dvdy.21854","article-title":"Ligand-specific function of transforming growth factor beta in epithelial-mesenchymal transition in heart development","volume":"238","author":"Azhar","year":"2009","journal-title":"Dev Dyn"},{"key":"10.1016\/j.carpath.2012.11.001_bb0105","doi-asserted-by":"crossref","first-page":"2127","DOI":"10.1002\/dvdy.22702","article-title":"Transforming growth factor beta 2 is required for valve remodeling during heart development","volume":"240","author":"Azhar","year":"2011","journal-title":"Dev Dyn"},{"key":"10.1016\/j.carpath.2012.11.001_bb0110","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1182\/blood.V87.1.1.1","article-title":"CD34: structure, biology, and clinical utility","volume":"87","author":"Krause","year":"1996","journal-title":"Blood"},{"key":"10.1016\/j.carpath.2012.11.001_bb0115","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1046\/j.1365-2141.2002.03604.x","article-title":"Transforming growth factor-beta1 causes transcriptional activation of CD34 and preserves haematopoietic stem\/progenitor cell activity","volume":"118","author":"Pierelli","year":"2002","journal-title":"Br J Haematol"},{"key":"10.1016\/j.carpath.2012.11.001_bb0120","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/j.prp.2005.02.001","article-title":"CD34+ fibrocytes in normal mitral valves and myxomatous mitral valve degeneration","volume":"201","author":"Barth","year":"2005","journal-title":"Pathol Res Pract"},{"key":"10.1016\/j.carpath.2012.11.001_bb0125","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1016\/j.ydbio.2006.03.027","article-title":"Hearts and bones: shared regulatory mechanisms in heart valve, cartilage, tendon, and bone development","volume":"294","author":"Lincoln","year":"2006","journal-title":"Dev Biol"},{"key":"10.1016\/j.carpath.2012.11.001_bb0130","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.ijcard.2010.11.004","article-title":"Biology of mitral valve prolapse: the harvest is big, but the workers are few","volume":"151","author":"Loardi","year":"2011","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.carpath.2012.11.001_bb0135","doi-asserted-by":"crossref","first-page":"e26769","DOI":"10.1371\/journal.pone.0026769","article-title":"Sox9 transcriptionally represses Spp 1 to prevent matrix mineralization in maturing heart valves and chondrocytes","volume":"6","author":"Peacock","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.carpath.2012.11.001_bb0140","doi-asserted-by":"crossref","first-page":"1522","DOI":"10.1161\/01.CIR.103.11.1522","article-title":"Bone formation and inflammation in cardiac valves","volume":"103","author":"Mohler","year":"2001","journal-title":"Circulation"},{"key":"10.1016\/j.carpath.2012.11.001_bb0145","doi-asserted-by":"crossref","first-page":"e20969","DOI":"10.1371\/journal.pone.0020969","article-title":"Preferential activation of SMAD1\/5\/8 on the fibrosa endothelium in calcified human aortic valves\u2014association with low BMP antagonists and SMAD6","volume":"6","author":"Ankeny","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.carpath.2012.11.001_bb0150","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1007\/s12565-009-0027-0","article-title":"Roles of TGFbeta and BMP during valvulo-septal endocardial cushion formation","volume":"84","author":"Yamagishi","year":"2009","journal-title":"Anat Sci Int"},{"key":"10.1016\/j.carpath.2012.11.001_bb0155","doi-asserted-by":"crossref","first-page":"1509","DOI":"10.1100\/tsw.2011.132","article-title":"The inter-relationship of periostin, TGF beta, and BMP in heart valve development and valvular heart diseases","volume":"11","author":"Conway","year":"2011","journal-title":"Scientific World Journal"},{"key":"10.1016\/j.carpath.2012.11.001_bb0160","doi-asserted-by":"crossref","first-page":"4489","DOI":"10.1073\/pnas.0308466101","article-title":"Bmp4 signaling is required for outflow-tract septation and branchial-arch artery remodeling","volume":"101","author":"Liu","year":"2004","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.carpath.2012.11.001_bb0165","doi-asserted-by":"crossref","first-page":"3200","DOI":"10.1002\/dvdy.21743","article-title":"BMP4 is required in the anterior heart field and its derivatives for endocardial cushion remodeling, outflow tract septation, and semilunar valve development","volume":"237","author":"McCulley","year":"2008","journal-title":"Dev Dyn"},{"key":"10.1016\/j.carpath.2012.11.001_bb0170","doi-asserted-by":"crossref","first-page":"2362","DOI":"10.1101\/gad.1124803","article-title":"An essential role of Bmp4 in the atrioventricular septation of the mouse heart","volume":"17","author":"Jiao","year":"2003","journal-title":"Genes Dev"},{"key":"10.1016\/j.carpath.2012.11.001_bb0175","doi-asserted-by":"crossref","first-page":"5601","DOI":"10.1242\/dev.02156","article-title":"Bmp2 is essential for cardiac cushion epithelial-mesenchymal transition and myocardial patterning","volume":"132","author":"Ma","year":"2005","journal-title":"Development"},{"key":"10.1016\/j.carpath.2012.11.001_bb0180","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1016\/j.ydbio.2004.01.045","article-title":"Bone morphogenetic protein-2 can mediate myocardial regulation of atrioventricular cushion mesenchymal cell formation in mice","volume":"269","author":"Sugi","year":"2004","journal-title":"Dev Biol"},{"key":"10.1016\/j.carpath.2012.11.001_bb0185","doi-asserted-by":"crossref","first-page":"2238","DOI":"10.1002\/dvdy.20838","article-title":"Proteolytic cleavage of versican during cardiac cushion morphogenesis","volume":"235","author":"Kern","year":"2006","journal-title":"Dev Dyn"},{"key":"10.1016\/j.carpath.2012.11.001_bb0190","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1016\/j.ydbio.2011.06.041","article-title":"Altered versican cleavage in ADAMTS5 deficient mice; a novel etiology of myxomatous valve disease","volume":"357","author":"Dupuis","year":"2011","journal-title":"Dev Biol"},{"key":"10.1016\/j.carpath.2012.11.001_bb0195","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1016\/j.matbio.2010.01.005","article-title":"Reduced versican cleavage due to Adamts9 haploinsufficiency is associated with cardiac and aortic anomalies","volume":"29","author":"Kern","year":"2010","journal-title":"Matrix Biol"},{"key":"10.1016\/j.carpath.2012.11.001_bb0200","doi-asserted-by":"crossref","first-page":"34298","DOI":"10.1074\/jbc.M111.254938","article-title":"Pericellular versican regulates the fibroblast-myofibroblast transition: a role for ADAMTS5 protease-mediated proteolysis","volume":"286","author":"Hattori","year":"2011","journal-title":"J Biol Chem"},{"key":"10.1016\/j.carpath.2012.11.001_bb0205","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/S0300-483X(00)00306-1","article-title":"Effects of antioxidant enzymes in the molecular control of reactive oxygen species toxicology","volume":"153","author":"Mates","year":"2000","journal-title":"Toxicology"},{"key":"10.1016\/j.carpath.2012.11.001_bb0210","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.abb.2010.03.019","article-title":"NAD(P)H:quinone acceptor oxidoreductase 1 (NQO1), a multifunctional antioxidant enzyme and exceptionally versatile cytoprotector","volume":"501","author":"Dinkova-Kostova","year":"2010","journal-title":"Arch Biochem Biophys"},{"key":"10.1016\/j.carpath.2012.11.001_bb0215","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.bbrc.2004.04.145","article-title":"Anti-oxidant adaptation in the AML cells supersensitive to hydrogen peroxide","volume":"319","author":"Oh","year":"2004","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.carpath.2012.11.001_bb0220","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.toxlet.2009.03.007","article-title":"Stable overexpression of human metallothionein-IIA in a heart-derived cell line confers oxidative protection","volume":"188","author":"Xue","year":"2009","journal-title":"Toxicol Lett"},{"key":"10.1016\/j.carpath.2012.11.001_bb0225","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1039\/c0mt00102c","article-title":"The \u201cmagic numbers\u201d of metallothionein","volume":"3","author":"Sutherland","year":"2011","journal-title":"Metallomics"},{"key":"10.1016\/j.carpath.2012.11.001_bb0230","doi-asserted-by":"crossref","first-page":"1176","DOI":"10.1096\/fj.03-1205com","article-title":"Loss of metal transcription factor-1 suppresses tumor growth through enhanced matrix deposition","volume":"18","author":"Haroon","year":"2004","journal-title":"FASEB J"},{"key":"10.1016\/j.carpath.2012.11.001_bb0235","doi-asserted-by":"crossref","first-page":"2498","DOI":"10.1161\/CIRCULATIONAHA.108.770776","article-title":"Basal and oxidative stress-induced expression of metallothionein is decreased in ascending aortic aneurysms of bicuspid aortic valve patients","volume":"119","author":"Phillippi","year":"2009","journal-title":"Circulation"},{"key":"10.1016\/j.carpath.2012.11.001_bb0240","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1016\/j.jacc.2008.05.043","article-title":"Dysregulation of antioxidant mechanisms contributes to increased oxidative stress in calcific aortic valvular stenosis in humans","volume":"52","author":"Miller","year":"2008","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.carpath.2012.11.001_bb0245","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.biocel.2005.06.018","article-title":"Cultured interstitial cells from human heart valves express both specific skeletal muscle and non-muscle markers","volume":"38","author":"Brand","year":"2006","journal-title":"Int J Biochem Cell Biol"},{"key":"10.1016\/j.carpath.2012.11.001_bb0250","doi-asserted-by":"crossref","first-page":"1437","DOI":"10.1098\/rstb.2007.2126","article-title":"Molecular and functional characteristics of heart-valve interstitial cells","volume":"362","author":"Chester","year":"2007","journal-title":"Philos Trans R Soc Lond B Biol Sci"},{"key":"10.1016\/j.carpath.2012.11.001_bb0255","first-page":"459","article-title":"Molecular characterization of interstitial cells isolated from human heart valves","volume":"9","author":"Roy","year":"2000","journal-title":"J Heart Valve Dis"},{"key":"10.1016\/j.carpath.2012.11.001_bb0260","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1007\/s00418-003-0570-z","article-title":"Smoothelin-positive cells in human and porcine semilunar valves","volume":"120","author":"Cimini","year":"2003","journal-title":"Histochem Cell Biol"},{"key":"10.1016\/j.carpath.2012.11.001_bb0265","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1016\/S0091-3057(01)00746-8","article-title":"Molecular, pharmacological and functional diversity of 5-HT receptors","volume":"71","author":"Hoyer","year":"2002","journal-title":"Pharmacol Biochem Behav"},{"key":"10.1016\/j.carpath.2012.11.001_bb0270","doi-asserted-by":"crossref","first-page":"2209","DOI":"10.1016\/S0002-9440(10)64497-5","article-title":"Serotonin mechanisms in heart valve disease II: the 5-HT2 receptor and its signaling pathway in aortic valve interstitial cells","volume":"161","author":"Xu","year":"2002","journal-title":"Am J Pathol"},{"key":"10.1016\/j.carpath.2012.11.001_bb0275","first-page":"71","article-title":"Tryptophan hydroxylase 1 expression is increased in phenotype-altered canine and human degenerative myxomatous mitral valves","volume":"19","author":"Disatian","year":"2010","journal-title":"J Heart Valve Dis"},{"key":"10.1016\/j.carpath.2012.11.001_bb0280","first-page":"44","article-title":"Autocrine serotonin and transforming growth factor beta 1 signaling mediates spontaneous myxomatous mitral valve disease","volume":"18","author":"Disatian","year":"2009","journal-title":"J Heart Valve Dis"},{"key":"10.1016\/j.carpath.2012.11.001_bb0285","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1517\/14740330902931524","article-title":"Serotonergic drugs and valvular heart disease","volume":"8","author":"Rothman","year":"2009","journal-title":"Expert Opin Drug Saf"},{"key":"10.1016\/j.carpath.2012.11.001_bb0290","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/j.pharmthera.2011.03.008","article-title":"Serotonin receptors and heart valve disease\u2014it was meant 2B","volume":"132","author":"Hutcheson","year":"2011","journal-title":"Pharmacol Ther"},{"key":"10.1016\/j.carpath.2012.11.001_bb0295","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1161\/01.CIR.92.4.790","article-title":"Carcinoid heart disease. Correlation of high serotonin levels with valvular abnormalities detected by cardiac catheterization and echocardiography","volume":"92","author":"Robiolio","year":"1995","journal-title":"Circulation"},{"key":"10.1016\/j.carpath.2012.11.001_bb0300","doi-asserted-by":"crossref","first-page":"1517","DOI":"10.1161\/01.CIR.0000159356.42064.48","article-title":"Long-term serotonin administration induces heart valve disease in rats","volume":"111","author":"Gustafsson","year":"2005","journal-title":"Circulation"},{"issue":"10","key":"10.1016\/j.carpath.2012.11.001_bb0305","doi-asserted-by":"crossref","first-page":"H1983","DOI":"10.1152\/ajpheart.00987.2011","article-title":"Local serotonin mediates cyclic strain-induced phenotype transformation, matrix degradation, and glycosaminoglycan synthesis in cultured sheep mitral valves","volume":"302","author":"Lacerda","year":"2012","journal-title":"Am J Physiol Heart Circ Physiol"},{"issue":"6","key":"10.1016\/j.carpath.2012.11.001_bb0310","doi-asserted-by":"crossref","first-page":"2111","DOI":"10.1016\/S0002-9440(10)64489-6","article-title":"Serotonin mechanisms in heart valve disease I: serotonin-induced up-regulation of transforming growth facto-beta1 via G-protein signal transduction in aortic valve interstitial cells","volume":"161","author":"Jian","year":"2002","journal-title":"Am J Pathol"}],"container-title":["Cardiovascular Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1054880712001470?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1054880712001470?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,2,4]],"date-time":"2022-02-04T13:57:03Z","timestamp":1643983023000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1054880712001470"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,7]]},"references-count":62,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2013,7]]}},"alternative-id":["S1054880712001470"],"URL":"https:\/\/doi.org\/10.1016\/j.carpath.2012.11.001","relation":{},"ISSN":["1054-8807"],"issn-type":[{"value":"1054-8807","type":"print"}],"subject":[],"published":{"date-parts":[[2013,7]]}}}