{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T16:50:34Z","timestamp":1762102234242},"reference-count":20,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,9,1]],"date-time":"2018-09-01T00:00:00Z","timestamp":1535760000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","cardiovascularpathology.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cardiovascular Pathology"],"published-print":{"date-parts":[[2018,9]]},"DOI":"10.1016\/j.carpath.2018.06.002","type":"journal-article","created":{"date-parts":[[2018,6,23]],"date-time":"2018-06-23T07:44:12Z","timestamp":1529739852000},"page":"35-41","update-policy":"http:\/\/dx.doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"special_numbering":"C","title":["Splenectomy had no significant impact on lipid metabolism and atherogenesis in Apoe deficient mice fed on a severe atherogenic diet"],"prefix":"10.1016","volume":"36","author":[{"given":"Ying","family":"Zhang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiangbo","family":"An","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiuyue","family":"Lin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jie","family":"Bai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Feng","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiawei","family":"Liao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.carpath.2018.06.002_bb0005","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1038\/nri1669","article-title":"Structure and function of the spleen","volume":"5","author":"Mebius","year":"2005","journal-title":"Nat Rev Immunol"},{"key":"10.1016\/j.carpath.2018.06.002_bb0010","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1097\/00000441-198601000-00006","article-title":"Increased low-density lipoprotein levels after splenectomy: a role for the spleen in cholesterol metabolism in myeloproliferative disorders","volume":"291","author":"Aviram","year":"1986","journal-title":"Am J Med Sci"},{"key":"10.1016\/j.carpath.2018.06.002_bb0015","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1002\/pbc.22640","article-title":"Traditional laboratory measures of cardiovascular risk in hereditary spherocytosis","volume":"55","author":"Crary","year":"2010","journal-title":"Pediatr Blood Cancer"},{"key":"10.1016\/j.carpath.2018.06.002_bb0020","first-page":"524","article-title":"Spleen and lipids metabolism - is there any correlation?","volume":"5","author":"Wysocki","year":"1999","journal-title":"Med Sci Monit"},{"key":"10.1016\/j.carpath.2018.06.002_bb0025","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1002\/(SICI)1096-8652(199707)55:3<129::AID-AJH2>3.0.CO;2-U","article-title":"Hypocholesterolemia in hairy cell leukemia: a marker for proliferative activity","volume":"55","author":"Pandolfino","year":"1997","journal-title":"Am J Hematol"},{"key":"10.1016\/j.carpath.2018.06.002_bb0030","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/S0140-6736(77)90132-5","article-title":"Splenectomy and subsequent mortality in veterans of the 1939-45 war","volume":"310","author":"Robinette","year":"1977","journal-title":"Lancet"},{"key":"10.1016\/j.carpath.2018.06.002_bb0035","doi-asserted-by":"crossref","first-page":"392","DOI":"10.3324\/haematol.2013.092460","article-title":"Long-term risks after splenectomy among 8,149 cancer-free American veterans: a cohort study with up to 27 years follow-up","volume":"99","author":"Kristinsson","year":"2014","journal-title":"Haematologica"},{"key":"10.1016\/j.carpath.2018.06.002_bb0040","doi-asserted-by":"crossref","DOI":"10.1097\/MD.0000000000000610","article-title":"Long-term risk of acute coronary syndrome in splenectomized patients due to splenic injury","volume":"94","author":"Tsai","year":"2015","journal-title":"Medicine"},{"key":"10.1016\/j.carpath.2018.06.002_bb0045","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1016\/j.carpath.2016.08.001","article-title":"The impact of splenectomy on human coronary artery atherosclerosis and vascular macrophage distribution","volume":"25","author":"Li","year":"2016","journal-title":"Cardiovasc Pathol"},{"key":"10.1016\/j.carpath.2018.06.002_bb0050","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.gene.2018.01.062","article-title":"Dyslipidemia, steatohepatitis and atherogenesis in lipodystrophic apoE deficient mice with Seipin deletion","volume":"648","author":"Liao","year":"2018","journal-title":"Gene"},{"key":"10.1016\/j.carpath.2018.06.002_bb0055","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1016\/j.bbrc.2015.03.117","article-title":"Dysfunction of lipid metabolism in lipodystrophic Seipin-deficient mice","volume":"461","author":"Wang","year":"2015","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.carpath.2018.06.002_bb0060","doi-asserted-by":"crossref","first-page":"133","DOI":"10.5551\/jat.33019","article-title":"Scavenger receptor class B type 1 deletion led to coronary atherosclerosis and ischemic heart disease in low-density lipoprotein receptor knockout mice on modified western-type diet","volume":"24","author":"Liao","year":"2017","journal-title":"J Atheroscler Thromb"},{"key":"10.1016\/j.carpath.2018.06.002_bb0065","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.ejphar.2017.05.010","article-title":"Animal models of atherosclerosis","volume":"816","author":"Emini Veseli","year":"2017","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.carpath.2018.06.002_bb0070","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1172\/JCI7272","article-title":"Protective immunity against atherosclerosis carried by B cells of hypercholesterolemic mice","volume":"109","author":"Caligiuri","year":"2002","journal-title":"J Clin Invest"},{"key":"10.1016\/j.carpath.2018.06.002_bb0075","doi-asserted-by":"crossref","first-page":"e231","DOI":"10.1016\/j.jss.2011.08.010","article-title":"Splenectomy increases atherosclerotic lesions in apolipoprotein E deficient mice","volume":"171","author":"Rezende","year":"2011","journal-title":"J Surg Res"},{"key":"10.1016\/j.carpath.2018.06.002_bb0080","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1161\/CIRCULATIONAHA.111.061986","article-title":"Extramedullary hematopoiesis generates Ly-6C(high) monocytes that infiltrate atherosclerotic lesions","volume":"125","author":"Robbins","year":"2012","journal-title":"Circulation"},{"key":"10.1016\/j.carpath.2018.06.002_bb0085","doi-asserted-by":"crossref","first-page":"4642","DOI":"10.1073\/pnas.94.9.4642","article-title":"T and B lymphocytes play a minor role in atherosclerotic plaque formation in the apolipoprotein E-deficient mouse","volume":"94","author":"Dansky","year":"1997","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.carpath.2018.06.002_bb0090","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1172\/JCI0215310","article-title":"Splenic immunity and atherosclerosis: a glimpse into a novel paradigm?","volume":"109","author":"Witztum","year":"2002","journal-title":"J Clin Invest"},{"key":"10.1016\/j.carpath.2018.06.002_bb0095","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1126\/science.1175202","article-title":"Identification of splenic reservoir monocytes and their deployment to inflammatory sites","volume":"325","author":"Swirski","year":"2009","journal-title":"Science"},{"key":"10.1016\/j.carpath.2018.06.002_bb0100","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1038\/nature11260","article-title":"Myocardial infarction accelerates atherosclerosis","volume":"487","author":"Dutta","year":"2012","journal-title":"Nature"}],"container-title":["Cardiovascular Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1054880718301595?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1054880718301595?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,7]],"date-time":"2018-09-07T13:47:39Z","timestamp":1536328059000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1054880718301595"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,9]]},"references-count":20,"alternative-id":["S1054880718301595"],"URL":"https:\/\/doi.org\/10.1016\/j.carpath.2018.06.002","relation":{},"ISSN":["1054-8807"],"issn-type":[{"type":"print","value":"1054-8807"}],"subject":[],"published":{"date-parts":[[2018,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Splenectomy had no significant impact on lipid metabolism and atherogenesis in Apoe deficient mice fed on a severe atherogenic diet","name":"articletitle","label":"Article Title"},{"value":"Cardiovascular Pathology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.carpath.2018.06.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}