{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,23]],"date-time":"2025-12-23T13:05:28Z","timestamp":1766495128760,"version":"3.48.0"},"reference-count":73,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Carbohydrate Research"],"published-print":{"date-parts":[[2026,2]]},"DOI":"10.1016\/j.carres.2025.109787","type":"journal-article","created":{"date-parts":[[2025,12,4]],"date-time":"2025-12-04T00:27:51Z","timestamp":1764808071000},"page":"109787","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Emerging insights into cell differentiation: the role of N-glycosylation in differentiation-based cancer therapies"],"prefix":"10.1016","volume":"560","author":[{"given":"Tiangui","family":"Wu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pengfei","family":"Ye","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junjie","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-9848-1574","authenticated-orcid":false,"given":"Yuhan","family":"Sun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.carres.2025.109787_bib1","doi-asserted-by":"crossref","first-page":"1803","DOI":"10.1042\/BST20210230","volume":"49","author":"Fulghieri","year":"2021","journal-title":"Biochem. Soc. Trans."},{"key":"10.1016\/j.carres.2025.109787_bib2","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/0753-3322(92)90083-J","volume":"46","author":"Degos","year":"1992","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.carres.2025.109787_bib3","volume":"2022","author":"Zhou","year":"2022","journal-title":"J. Immunol. Res."},{"key":"10.1016\/j.carres.2025.109787_bib4","volume":"54","author":"Liu","year":"2022","journal-title":"Redox Biol."},{"key":"10.1016\/j.carres.2025.109787_bib5","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1038\/s41419-024-06432-z","volume":"15","author":"Iwamoto","year":"2024","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.carres.2025.109787_bib6","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.celrep.2016.12.017","volume":"18","author":"Matoba","year":"2017","journal-title":"Cell Rep."},{"key":"10.1016\/j.carres.2025.109787_bib7","volume":"23","author":"Po\u017aniak","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.carres.2025.109787_bib8","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.178804","volume":"9","author":"Hollander","year":"2024","journal-title":"JCI Insight"},{"key":"10.1016\/j.carres.2025.109787_bib9","volume":"300","author":"Wu","year":"2024","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.carres.2025.109787_bib10","doi-asserted-by":"crossref","first-page":"2500","DOI":"10.1074\/jbc.M111.303123","volume":"287","author":"Li","year":"2012","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.carres.2025.109787_bib11","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1038\/nrc3982","volume":"15","author":"Pinho","year":"2015","journal-title":"Nat. Rev. Cancer"},{"first-page":"597","year":"2015","series-title":"Essentials of Glycobiology, Cold Spring Harbor Laboratory Press Copyright 2015-2017 by the Consortium of Glycobiology","key":"10.1016\/j.carres.2025.109787_bib12"},{"key":"10.1016\/j.carres.2025.109787_bib13","volume":"79","author":"Taniguchi","year":"2021","journal-title":"Mol. Aspect. Med."},{"key":"10.1016\/j.carres.2025.109787_bib14","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbrc.2024.149541","volume":"710","author":"Suzuki","year":"2024","journal-title":"Biochem. Biophys. Res. Commun."},{"first-page":"103","year":"2022","series-title":"Essentials of Glycobiology, Cold Spring Harbor Laboratory Press Copyright \u00a9 2022 the Consortium of Glycobiology","key":"10.1016\/j.carres.2025.109787_bib15"},{"key":"10.1016\/j.carres.2025.109787_bib16","doi-asserted-by":"crossref","first-page":"R229","DOI":"10.1016\/j.cub.2019.01.003","volume":"29","author":"Eichler","year":"2019","journal-title":"Curr. Biol."},{"key":"10.1016\/j.carres.2025.109787_bib17","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1016\/j.cell.2008.11.047","volume":"136","author":"Ruiz-Canada","year":"2009","journal-title":"Cell"},{"key":"10.1016\/j.carres.2025.109787_bib18","doi-asserted-by":"crossref","DOI":"10.1101\/cshperspect.a013201","volume":"5","author":"Braakman","year":"2013","journal-title":"Cold Spring Harbor Perspect. Biol."},{"key":"10.1016\/j.carres.2025.109787_bib19","doi-asserted-by":"crossref","first-page":"4322","DOI":"10.1111\/febs.15330","volume":"287","author":"Kozlov","year":"2020","journal-title":"FEBS J."},{"key":"10.1016\/j.carres.2025.109787_bib20","doi-asserted-by":"crossref","first-page":"138","DOI":"10.3389\/fonc.2014.00138","volume":"4","author":"Fortuna-Costa","year":"2014","journal-title":"Front. Oncol."},{"key":"10.1016\/j.carres.2025.109787_bib21","doi-asserted-by":"crossref","first-page":"13811","DOI":"10.1074\/jbc.271.23.13811","volume":"271","author":"Yoshimura","year":"1996","journal-title":"J. Biol. Chem."},{"first-page":"445","year":"2010","series-title":"Methods in Enzymology","key":"10.1016\/j.carres.2025.109787_bib22"},{"key":"10.1016\/j.carres.2025.109787_bib23","doi-asserted-by":"crossref","first-page":"9275","DOI":"10.1074\/jbc.272.14.9275","volume":"272","author":"Rebbaa","year":"1997","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.carres.2025.109787_bib24","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.bbamcr.2003.10.004","volume":"1643","author":"Poche\u0107","year":"2003","journal-title":"Biochim. Biophys. Acta Mol. Cell Res."},{"key":"10.1016\/j.carres.2025.109787_bib25","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1093\/glycob\/cwh016","volume":"14","author":"Gu","year":"2004","journal-title":"Glycobiology"},{"key":"10.1016\/j.carres.2025.109787_bib26","doi-asserted-by":"crossref","first-page":"9549","DOI":"10.1021\/ja301694s","volume":"134","author":"Belardi","year":"2012","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.carres.2025.109787_bib27","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1186\/s13046-018-0935-8","volume":"37","author":"Wu","year":"2018","journal-title":"J. Exp. Clin. Cancer Res."},{"key":"10.1016\/j.carres.2025.109787_bib28","doi-asserted-by":"crossref","first-page":"984","DOI":"10.1074\/jbc.M117.808584","volume":"293","author":"Chakraborty","year":"2018","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.carres.2025.109787_bib29","doi-asserted-by":"crossref","first-page":"71","DOI":"10.3389\/fendo.2011.00071","volume":"2","author":"Albu","year":"2011","journal-title":"Front. Endocrinol."},{"key":"10.1016\/j.carres.2025.109787_bib30","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1158\/2159-8290.CD-14-0788","volume":"5","author":"Chaffer","year":"2015","journal-title":"Cancer Discov."},{"key":"10.1016\/j.carres.2025.109787_bib31","doi-asserted-by":"crossref","first-page":"8721","DOI":"10.7150\/thno.41648","volume":"10","author":"Huang","year":"2020","journal-title":"Theranostics"},{"key":"10.1016\/j.carres.2025.109787_bib32","doi-asserted-by":"crossref","first-page":"8560","DOI":"10.1074\/jbc.RA119.012280","volume":"295","author":"Alam","year":"2020","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.carres.2025.109787_bib33","doi-asserted-by":"crossref","first-page":"1186","DOI":"10.1126\/science.aaz2121","volume":"370","author":"Kasper","year":"2020","journal-title":"Science"},{"key":"10.1016\/j.carres.2025.109787_bib34","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1016\/j.molcel.2014.04.026","volume":"54","author":"Ferrer","year":"2014","journal-title":"Mol. Cell"},{"key":"10.1016\/j.carres.2025.109787_bib35","doi-asserted-by":"crossref","first-page":"3787","DOI":"10.1038\/emboj.2010.254","volume":"29","author":"Park","year":"2010","journal-title":"EMBO J."},{"key":"10.1016\/j.carres.2025.109787_bib36","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0146887","volume":"11","author":"Priglinger","year":"2016","journal-title":"PLoS One"},{"key":"10.1016\/j.carres.2025.109787_bib37","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1038\/s41419-024-07028-3","volume":"15","author":"Hsu","year":"2024","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.carres.2025.109787_bib38","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1007\/s13402-023-00770-4","volume":"46","author":"de-Souza-Ferreira","year":"2023","journal-title":"Cell. Oncol."},{"key":"10.1016\/j.carres.2025.109787_bib39","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1158\/0008-5472.CAN-07-1340","volume":"68","author":"Hedlund","year":"2008","journal-title":"Cancer Res."},{"key":"10.1016\/j.carres.2025.109787_bib40","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1007\/BF02739872","volume":"6","author":"Lahr","year":"1995","journal-title":"Endocr. Pathol."},{"key":"10.1016\/j.carres.2025.109787_bib41","volume":"42","author":"Wei","year":"2023","journal-title":"Cell Rep."},{"key":"10.1016\/j.carres.2025.109787_bib42","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1111\/j.1365-2141.1984.tb02910.x","volume":"57","author":"Nilsson","year":"1984","journal-title":"Br. J. Haematol."},{"key":"10.1016\/j.carres.2025.109787_bib43","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1038\/nrc.2017.103","volume":"18","author":"de Th\u00e9","year":"2018","journal-title":"Nat. Rev. Cancer"},{"key":"10.1016\/j.carres.2025.109787_bib44","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1038\/nm.3441","volume":"20","author":"Ablain","year":"2014","journal-title":"Nat. Med."},{"key":"10.1016\/j.carres.2025.109787_bib45","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1038\/s41375-023-02131-4","volume":"38","author":"Sung","year":"2024","journal-title":"Leukemia"},{"key":"10.1016\/j.carres.2025.109787_bib46","doi-asserted-by":"crossref","first-page":"1196","DOI":"10.1111\/cas.16090","volume":"115","author":"Liu","year":"2024","journal-title":"Cancer Sci."},{"key":"10.1016\/j.carres.2025.109787_bib47","doi-asserted-by":"crossref","first-page":"2916","DOI":"10.1016\/j.neuron.2022.07.012","volume":"110","author":"Zeineldin","year":"2022","journal-title":"Neuron"},{"key":"10.1016\/j.carres.2025.109787_bib48","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1016\/j.cell.2014.02.030","volume":"157","author":"Suv\u00e0","year":"2014","journal-title":"Cell"},{"key":"10.1016\/j.carres.2025.109787_bib49","doi-asserted-by":"crossref","DOI":"10.1016\/j.critrevonc.2022.103854","volume":"180","author":"Zheng","year":"2022","journal-title":"Crit. Rev. Oncol. Hematol."},{"key":"10.1016\/j.carres.2025.109787_bib50","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1186\/s12967-023-04396-w","volume":"21","author":"Lei","year":"2023","journal-title":"J. Transl. Med."},{"key":"10.1016\/j.carres.2025.109787_bib51","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1186\/s12885-020-6699-5","volume":"20","author":"Takayama","year":"2020","journal-title":"BMC Cancer"},{"key":"10.1016\/j.carres.2025.109787_bib52","doi-asserted-by":"crossref","first-page":"8264","DOI":"10.1038\/srep08264","volume":"5","author":"Wang","year":"2015","journal-title":"Sci. Rep."},{"key":"10.1016\/j.carres.2025.109787_bib53","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1074\/mcp.M115.051235","volume":"15","author":"Holst","year":"2016","journal-title":"Mol. Cell. Proteomics"},{"key":"10.1016\/j.carres.2025.109787_bib54","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbamcr.2019.118555","volume":"1866","author":"Link-Lenczowski","year":"2019","journal-title":"Biochim. Biophys. Acta Mol. Cell Res."},{"key":"10.1016\/j.carres.2025.109787_bib55","doi-asserted-by":"crossref","first-page":"5183","DOI":"10.1038\/s41467-020-18987-4","volume":"11","author":"Brady","year":"2020","journal-title":"Nat. Commun."},{"key":"10.1016\/j.carres.2025.109787_bib56","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1002\/1097-0142(197102)27:2<374::AID-CNCR2820270221>3.0.CO;2-G","volume":"27","author":"Evans","year":"1971","journal-title":"Cancer"},{"key":"10.1016\/j.carres.2025.109787_bib57","doi-asserted-by":"crossref","first-page":"1046","DOI":"10.1016\/S0140-6736(71)91606-0","volume":"1","author":"D'Angio","year":"1971","journal-title":"Lancet"},{"key":"10.1016\/j.carres.2025.109787_bib58","doi-asserted-by":"crossref","first-page":"513","DOI":"10.3389\/fonc.2018.00513","volume":"8","author":"Rossig","year":"2018","journal-title":"Front. Oncol."},{"key":"10.1016\/j.carres.2025.109787_bib59","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/0014-4827(83)90347-6","volume":"149","author":"Richter-Landsberg","year":"1983","journal-title":"Exp. Cell Res."},{"key":"10.1016\/j.carres.2025.109787_bib60","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1016\/j.febslet.2005.12.089","volume":"580","author":"Inamori","year":"2006","journal-title":"FEBS Lett."},{"key":"10.1016\/j.carres.2025.109787_bib61","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1038\/s41423-020-0488-6","volume":"17","author":"Zhang","year":"2020","journal-title":"Cell. Mol. Immunol."},{"key":"10.1016\/j.carres.2025.109787_bib62","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1038\/ni1102-999","volume":"3","author":"Khong","year":"2002","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.carres.2025.109787_bib63","doi-asserted-by":"crossref","first-page":"29329","DOI":"10.1074\/jbc.M115.674671","volume":"290","author":"Chien","year":"2015","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.carres.2025.109787_bib64","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.immuni.2022.12.008","volume":"56","author":"Park","year":"2023","journal-title":"Immunity"},{"key":"10.1016\/j.carres.2025.109787_bib65","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1189\/jlb.2VMA0915-432RR","volume":"99","author":"Hauser","year":"2016","journal-title":"J. Leukoc. Biol."},{"key":"10.1016\/j.carres.2025.109787_bib66","doi-asserted-by":"crossref","first-page":"605","DOI":"10.4049\/jimmunol.0901698","volume":"185","author":"Rodr\u00edguez-Prados","year":"2010","journal-title":"J. Immunol."},{"key":"10.1016\/j.carres.2025.109787_bib67","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1016\/j.immuni.2015.02.005","volume":"42","author":"Jha","year":"2015","journal-title":"Immunity"},{"key":"10.1016\/j.carres.2025.109787_bib68","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1186\/s12964-023-01432-6","volume":"22","author":"He","year":"2024","journal-title":"Cell Commun. Signal."},{"key":"10.1016\/j.carres.2025.109787_bib69","doi-asserted-by":"crossref","first-page":"1427","DOI":"10.3389\/fimmu.2017.01427","volume":"8","author":"Lynch","year":"2017","journal-title":"Front. Immunol."},{"key":"10.1016\/j.carres.2025.109787_bib70","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1038\/s41423-021-00753-1","volume":"19","author":"M\u00f8ller","year":"2022","journal-title":"Cell. Mol. Immunol."},{"key":"10.1016\/j.carres.2025.109787_bib71","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1126\/science.adg1955","volume":"383","author":"Sharma","year":"2024","journal-title":"Science"},{"key":"10.1016\/j.carres.2025.109787_bib72","doi-asserted-by":"crossref","first-page":"552","DOI":"10.2174\/1389201022666210820093608","volume":"23","author":"Chin","year":"2022","journal-title":"Curr. Pharm. Biotechnol."},{"key":"10.1016\/j.carres.2025.109787_bib73","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2303867120","volume":"120","author":"Kawahara","year":"2023","journal-title":"Proc. Natl. Acad. Sci. U. S. A."}],"container-title":["Carbohydrate Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0008621525004136?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0008621525004136?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,12,23]],"date-time":"2025-12-23T13:03:17Z","timestamp":1766494997000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0008621525004136"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2]]},"references-count":73,"alternative-id":["S0008621525004136"],"URL":"https:\/\/doi.org\/10.1016\/j.carres.2025.109787","relation":{},"ISSN":["0008-6215"],"issn-type":[{"type":"print","value":"0008-6215"}],"subject":[],"published":{"date-parts":[[2026,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Emerging insights into cell differentiation: the role of N-glycosylation in differentiation-based cancer therapies","name":"articletitle","label":"Article Title"},{"value":"Carbohydrate Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.carres.2025.109787","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"109787"}}