{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T08:27:29Z","timestamp":1790065649541,"version":"4.0.1"},"reference-count":164,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2017,7,1]],"date-time":"2017-07-01T00:00:00Z","timestamp":1498867200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,7,1]],"date-time":"2017-07-01T00:00:00Z","timestamp":1498867200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cardiovascular Revascularization Medicine"],"published-print":{"date-parts":[[2017,7]]},"DOI":"10.1016\/j.carrev.2017.02.004","type":"journal-article","created":{"date-parts":[[2017,2,8]],"date-time":"2017-02-08T10:17:37Z","timestamp":1486549057000},"page":"374-383","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"title":["A review of strategies for infarct size reduction during acute myocardial infarction"],"prefix":"10.1016","volume":"18","author":[{"given":"Yasir","family":"Parviz","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sethumadhavan","family":"Vijayan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6105-8084","authenticated-orcid":false,"given":"Shahar","family":"Lavi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.carrev.2017.02.004_bb0005","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1016\/j.jacc.2010.05.008","article-title":"Treatments, trends, and outcomes of acute myocardial infarction and percutaneous coronary intervention","volume":"56","author":"Roe","year":"2010","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.carrev.2017.02.004_bb0010","doi-asserted-by":"crossref","first-page":"1848","DOI":"10.1161\/CIRCULATIONAHA.111.047480","article-title":"Twenty-two-year trends in incidence of myocardial infarction, coronary heart disease mortality, and case fatality in 4 US communities, 1987-2008","volume":"125","author":"Rosamond","year":"2012","journal-title":"Circulation"},{"key":"10.1016\/j.carrev.2017.02.004_bb0015","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1161\/01.CIR.97.8.765","article-title":"Prognostic significance of microvascular obstruction by magnetic resonance imaging in patients with acute myocardial infarction","volume":"97","author":"Wu","year":"1998","journal-title":"Circulation"},{"key":"10.1016\/j.carrev.2017.02.004_bb0020","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/S0735-1097(01)01711-9","article-title":"The relationships of left ventricular ejection fraction, end-systolic volume index and infarct size to six-month mortality after hospital discharge following myocardial infarction treated by thrombolysis","volume":"39","author":"Burns","year":"2002","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.carrev.2017.02.004_bb0025","doi-asserted-by":"crossref","first-page":"1533","DOI":"10.1016\/j.jacc.2004.06.071","article-title":"The quantification of infarct size","volume":"44","author":"Gibbons","year":"2004","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.carrev.2017.02.004_bb0030","doi-asserted-by":"crossref","first-page":"1454","DOI":"10.1016\/j.jacc.2015.02.032","article-title":"Evolving therapies for myocardial ischemia\/reperfusion injury","volume":"65","author":"Ibanez","year":"2015","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.carrev.2017.02.004_bb0035","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1016\/j.jcin.2010.05.004","article-title":"Prevention and treatment of microvascular obstruction-related myocardial injury and coronary no-reflow following percutaneous coronary intervention: a systematic approach","volume":"3","author":"Jaffe","year":"2010","journal-title":"JACC Cardiovasc Interv"},{"key":"10.1016\/j.carrev.2017.02.004_bb0040","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/j.jacc.2009.03.054","article-title":"Myocardial no-reflow in humans","volume":"54","author":"Niccoli","year":"2009","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.carrev.2017.02.004_bb0045","doi-asserted-by":"crossref","first-page":"2302","DOI":"10.1161\/01.CIR.97.23.2302","article-title":"Angiographic assessment of myocardial reperfusion in patients treated with primary angioplasty for acute myocardial infarction: myocardial blush grade. Zwolle myocardial infarction study group","volume":"97","author":"van\u2019t Hof","year":"1998","journal-title":"Circulation"},{"key":"10.1016\/j.carrev.2017.02.004_bb0050","doi-asserted-by":"crossref","first-page":"1659","DOI":"10.1161\/01.CIR.91.6.1659","article-title":"Predictors of 30-day mortality in the era of reperfusion for acute myocardial infarction. Results from an international trial of 41,021 patients. GUSTO-I investigators","volume":"91","author":"Lee","year":"1995","journal-title":"Circulation"},{"key":"10.1016\/j.carrev.2017.02.004_bb0055","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1016\/0735-1097(94)00367-Y","article-title":"Predictors of in-hospital and 6-month outcome after acute myocardial infarction in the reperfusion era: the primary angioplasty in myocardial infarction (PAMI) trail","volume":"25","author":"Stone","year":"1995","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.carrev.2017.02.004_bb0060","doi-asserted-by":"crossref","first-page":"1121","DOI":"10.1161\/01.CIR.0000118496.44135.A7","article-title":"Impact of microvascular dysfunction on left ventricular remodeling and long-term clinical outcome after primary coronary angioplasty for acute myocardial infarction","volume":"109","author":"Bolognese","year":"2004","journal-title":"Circulation"},{"key":"10.1016\/j.carrev.2017.02.004_bb0065","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1161\/01.CIR.95.2.320","article-title":"Apoptosis in human acute myocardial infarction","volume":"95","author":"Saraste","year":"1997","journal-title":"Circulation"},{"key":"10.1016\/j.carrev.2017.02.004_bb0070","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/S0167-5273(96)02854-9","article-title":"Reperfusion injury: a review of the pathophysiology, clinical manifestations and therapeutic options","volume":"58","author":"Maxwell","year":"1997","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.carrev.2017.02.004_bb0075","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1053\/euhj.2000.2172","article-title":"The coronary no-reflow phenomenon: a review of mechanisms and therapies","volume":"22","author":"Eeckhout","year":"2001","journal-title":"Eur Heart J"},{"key":"10.1016\/j.carrev.2017.02.004_bb0080","first-page":"00180","article-title":"The no-reflow phenomenon: state of the art","volume":"23","author":"Bouleti","year":"2015","journal-title":"Arch Cardiovasc Dis"},{"key":"10.1016\/j.carrev.2017.02.004_bb0085","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1067\/mhj.2003.36","article-title":"No-reflow is an independent predictor of death and myocardial infarction after percutaneous coronary intervention","volume":"145","author":"Resnic","year":"2003","journal-title":"Am Heart J"},{"key":"10.1016\/j.carrev.2017.02.004_bb0090","doi-asserted-by":"crossref","first-page":"264","DOI":"10.7326\/0003-4819-114-4-264","article-title":"Limitations of the electrocardiogram in estimating infarction size after acute reperfusion therapy for myocardial infarction","volume":"114","author":"Christian","year":"1991","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.carrev.2017.02.004_bb0095","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1016\/j.ahj.2004.10.014","article-title":"Electrocardiographic infarct size assessment after thrombolysis: insights from the acute myocardial infarction STudy ADenosine (AMISTAD) trial","volume":"150","author":"Barbagelata","year":"2005","journal-title":"Am Heart J"},{"key":"10.1016\/j.carrev.2017.02.004_bb0100","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1016\/0002-9149(88)91060-0","article-title":"Use of initial ST-segment deviation for prediction of final electrocardiographic size of acute myocardial infarcts","volume":"61","author":"Aldrich","year":"1988","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.carrev.2017.02.004_bb0105","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1136\/heart.87.6.520","article-title":"Troponin T concentrations 72hours after myocardial infarction as a serological estimate of infarct size","volume":"87","author":"Licka","year":"2002","journal-title":"Heart"},{"key":"10.1016\/j.carrev.2017.02.004_bb0110","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1016\/j.jcmg.2011.03.010","article-title":"Troponin T levels and infarct size by SPECT myocardial perfusion imaging","volume":"4","author":"Arruda-Olson","year":"2011","journal-title":"JACC Cardiovasc Imaging"},{"key":"10.1016\/j.carrev.2017.02.004_bb0115","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1161\/01.CIR.52.5.743","article-title":"An improved basis for enzymatic estimation of infarct size","volume":"52","author":"Roberts","year":"1975","journal-title":"Circulation"},{"key":"10.1016\/j.carrev.2017.02.004_bb0120","doi-asserted-by":"crossref","first-page":"824","DOI":"10.1161\/01.CIR.70.5.824","article-title":"Comparison of enzymatic and anatomic estimates of myocardial infarct size in man","volume":"70","author":"Hackel","year":"1984","journal-title":"Circulation"},{"key":"10.1016\/j.carrev.2017.02.004_bb0125","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1097\/00019501-199707000-00005","article-title":"Serum levels of cardiac troponin I and troponin T in estimating myocardial infarct size soon after reperfusion","volume":"8","author":"Tanaka","year":"1997","journal-title":"Coron Artery Dis"},{"key":"10.1016\/j.carrev.2017.02.004_bb0130","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1016\/j.jcin.2008.04.010","article-title":"Utility of cardiac biomarkers in predicting infarct size, left ventricular function, and clinical outcome after primary percutaneous coronary intervention for ST-segment elevation myocardial infarction","volume":"1","author":"Chia","year":"2008","journal-title":"JACC Cardiovasc Interv"},{"key":"10.1016\/j.carrev.2017.02.004_bb0135","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1016\/j.ahj.2014.07.009","article-title":"Sevoflurane in acute myocardial infarction: a pilot randomized study","volume":"168","author":"Lavi","year":"2014","journal-title":"Am Heart J"},{"key":"10.1016\/j.carrev.2017.02.004_bb0140","doi-asserted-by":"crossref","first-page":"1277","DOI":"10.1161\/01.CIR.80.5.1277","article-title":"Feasibility of tomographic 99mTc-hexakis-2-methoxy-2-methylpropyl-isonitrile imaging for the assessment of myocardial area at risk and the effect of treatment in acute myocardial infarction","volume":"80","author":"Gibbons","year":"1989","journal-title":"Circulation"},{"key":"10.1016\/j.carrev.2017.02.004_bb0145","doi-asserted-by":"crossref","first-page":"1010","DOI":"10.1161\/01.CIR.94.5.1010","article-title":"Assessment of myocardial viability with 99mTc sestamibi in patients undergoing cardiac transplantation. A scintigraphic\/pathological study","volume":"94","author":"Medrano","year":"1996","journal-title":"Circulation"},{"key":"10.1016\/j.carrev.2017.02.004_bb0150","doi-asserted-by":"crossref","first-page":"1678","DOI":"10.1161\/01.CIR.102.14.1678","article-title":"Early assessment of myocardial salvage by contrast-enhanced magnetic resonance imaging","volume":"102","author":"Hillenbrand","year":"2000","journal-title":"Circulation"},{"key":"10.1016\/j.carrev.2017.02.004_bb0155","doi-asserted-by":"crossref","first-page":"1711","DOI":"10.1016\/S0735-1097(99)00418-0","article-title":"Adenosine as an adjunct to thrombolytic therapy for acute myocardial infarction: results of a multicenter, randomized, placebo-controlled trial: the acute myocardial infarction STudy of ADenosine (AMISTAD) trial","volume":"34","author":"Mahaffey","year":"1999","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.carrev.2017.02.004_bb0160","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/S0002-8703(03)00172-8","volume":"146","author":"Kopecky","year":"2003","journal-title":"Am Heart J"},{"key":"10.1016\/j.carrev.2017.02.004_bb0165","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1148\/radiol.2261012108","article-title":"Acute myocardial infarction: myocardial viability assessment in patients early thereafter comparison of contrast-enhanced MR imaging with resting (201)Tl SPECT. Single photon emission computed tomography","volume":"226","author":"Kitagawa","year":"2003","journal-title":"Radiology"},{"key":"10.1016\/j.carrev.2017.02.004_bb0170","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1016\/S0140-6736(03)12389-6","article-title":"Contrast-enhanced MRI and routine single photon emission computed tomography (SPECT) perfusion imaging for detection of subendocardial myocardial infarcts: an imaging study","volume":"361","author":"Wagner","year":"2003","journal-title":"Lancet"},{"key":"10.1016\/j.carrev.2017.02.004_bb0175","doi-asserted-by":"crossref","first-page":"2660","DOI":"10.1093\/eurheartj\/ehq247","article-title":"Impact of early vs. late microvascular obstruction assessed by magnetic resonance imaging on long-term outcome after ST-elevation myocardial infarction: a comparison with traditional prognostic markers","volume":"31","author":"de Waha","year":"2010","journal-title":"Eur Heart J"},{"key":"10.1016\/j.carrev.2017.02.004_bb0180","doi-asserted-by":"crossref","first-page":"2459","DOI":"10.1016\/j.jacc.2010.02.033","volume":"55","author":"Larose","year":"2010","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.carrev.2017.02.004_bb0185","doi-asserted-by":"crossref","first-page":"1217","DOI":"10.1016\/j.jacc.2014.06.1194","article-title":"Comprehensive prognosis assessment by CMR imaging after ST-segment elevation myocardial infarction","volume":"64","author":"Eitel","year":"2014","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.carrev.2017.02.004_bb0190","doi-asserted-by":"crossref","first-page":"1847","DOI":"10.1161\/01.CIR.82.5.1847","article-title":"Left ventricular ejection fraction may not be useful as an end point of thrombolytic therapy comparative trials","volume":"82","author":"Califf","year":"1990","journal-title":"Circulation"},{"key":"10.1016\/j.carrev.2017.02.004_bb0195","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1161\/CIRCIMAGING.109.910521","article-title":"Strain echocardiography and wall motion score index predicts final infarct size in patients with non-ST-segment-elevation myocardial infarction","volume":"3","author":"Eek","year":"2010","journal-title":"Circ Cardiovasc Imaging"},{"key":"10.1016\/j.carrev.2017.02.004_bb0200","doi-asserted-by":"crossref","first-page":"678","DOI":"10.1093\/ejechocard\/jer113","article-title":"Assessment of left ventricular function in ST-elevation myocardial infarction by global longitudinal strain: a comparison with ejection fraction, infarct size, and wall motion score index measured by non-invasive imaging modalities","volume":"12","author":"Mistry","year":"2011","journal-title":"Eur J Echocardiogr"},{"key":"10.1016\/j.carrev.2017.02.004_bb0205","first-page":"56","article-title":"Myocardial resistance assessed by guidewire-based pressure\u2013temperature measurement: in vitro validation","volume":"62","author":"Aarnoudse","year":"2004","journal-title":"Catheter Cardiovasc Interv"},{"key":"10.1016\/j.carrev.2017.02.004_bb0210","doi-asserted-by":"crossref","first-page":"3129","DOI":"10.1161\/01.CIR.0000080700.98607.D1","article-title":"Novel index for invasively assessing the coronary microcirculation","volume":"107","author":"Fearon","year":"2003","journal-title":"Circulation"},{"key":"10.1016\/j.carrev.2017.02.004_bb0215","doi-asserted-by":"crossref","first-page":"1833","DOI":"10.1161\/CIRCULATIONAHA.116.022603","article-title":"Comparative prognostic utility of indexes of microvascular function alone or in combination in patients with an acute ST-segment-elevation myocardial infarction","volume":"134","author":"Carrick","year":"2016","journal-title":"Circulation"},{"key":"10.1016\/j.carrev.2017.02.004_bb0220","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/S0140-6736(03)12113-7","article-title":"Primary angioplasty versus intravenous thrombolytic therapy for acute myocardial infarction: a quantitative review of 23 randomised trials","volume":"361","author":"Keeley","year":"2003","journal-title":"Lancet"},{"key":"10.1016\/j.carrev.2017.02.004_bb0225","doi-asserted-by":"crossref","first-page":"E22","DOI":"10.1016\/S0002-8703(03)00424-1","article-title":"Early reperfusion and late clinical outcomes in patients presenting with acute myocardial infarction randomly assigned to primary percutaneous coronary intervention or streptokinase","volume":"146","author":"Berrocal","year":"2003","journal-title":"Am Heart J"},{"key":"10.1016\/j.carrev.2017.02.004_bb0230","doi-asserted-by":"crossref","first-page":"2651","DOI":"10.1161\/CIRCULATIONAHA.105.551770","article-title":"Devices for distal protection during percutaneous coronary revascularization","volume":"113","author":"Mauri","year":"2006","journal-title":"Circulation"},{"key":"10.1016\/j.carrev.2017.02.004_bb0235","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1007\/s00392-009-0756-z","article-title":"Immediate versus delayed angioplasty in infarct-related arteries with TIMI III flow and ST segment recovery: a matched comparison in acute myocardial infarction patients","volume":"98","author":"Meneveau","year":"2009","journal-title":"Clin Res Cardiol"},{"key":"10.1016\/j.carrev.2017.02.004_bb0240","doi-asserted-by":"crossref","first-page":"2088","DOI":"10.1016\/j.jacc.2014.02.530","article-title":"A randomized trial of deferred stenting versus immediate stenting to prevent no- or slow-reflow in acute ST-segment elevation myocardial infarction (DEFER-STEMI)","volume":"63","author":"Carrick","year":"2014","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.carrev.2017.02.004_bb0245","doi-asserted-by":"crossref","first-page":"2199","DOI":"10.1016\/S0140-6736(16)30072-1","article-title":"Deferred versus conventional stent implantation in patients with ST-segment elevation myocardial infarction (DANAMI 3-DEFER): an open-label, randomised controlled trial","volume":"387","author":"Kelbaek","year":"2016","journal-title":"Lancet"},{"key":"10.1016\/j.carrev.2017.02.004_bb0250","doi-asserted-by":"crossref","first-page":"e003388","DOI":"10.1161\/CIRCINTERVENTIONS.115.003388","article-title":"Comparison of immediate with delayed stenting using the minimalist immediate mechanical intervention approach in acute ST-segment-elevation myocardial infarction: the MIMI study","volume":"9","author":"Belle","year":"2016","journal-title":"Circ Cardiovasc Interv"},{"key":"10.1016\/j.carrev.2017.02.004_bb0255","doi-asserted-by":"crossref","first-page":"2199","DOI":"10.1016\/S0140-6736(16)30072-1","article-title":"Deferred versus conventional stent implantation in patients with ST-segment elevation myocardial infarction (DANAMI 3-DEFER): an open-label, randomised controlled trial","volume":"387","author":"Kelbaek","year":"2016","journal-title":"Lancet"},{"key":"10.1016\/j.carrev.2017.02.004_bb0260","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCINTERVENTIONS.116.004101","article-title":"INNOVATION study (impact of immediate stent implantation versus deferred stent implantation on infarct size and microvascular perfusion in patients with ST-segment-elevation myocardial infarction)","volume":"9","author":"Kim","year":"2016","journal-title":"Circ Cardiovasc Interv"},{"key":"10.1016\/j.carrev.2017.02.004_bb0265","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1186\/1532-429X-16-38","article-title":"Prevalence and extent of infarct and microvascular obstruction following different reperfusion therapies in ST-elevation myocardial infarction","volume":"16","author":"Khan","year":"2014","journal-title":"J Cardiovasc Magn Reson"},{"key":"10.1016\/j.carrev.2017.02.004_bb0270","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1001\/jama.293.9.1063","article-title":"Distal microcirculatory protection during percutaneous coronary intervention in acute ST-segment elevation myocardial infarction: a randomized controlled trial","volume":"293","author":"Stone","year":"2005","journal-title":"JAMA"},{"key":"10.1016\/j.carrev.2017.02.004_bb0275","first-page":"132","article-title":"Limitations of using a GuardWire temporary occlusion and aspiration system in patients with acute myocardial infarction: multicenter investigation of coronary artery protection with a distal occlusion device in acute myocardial infarction (MICADO)","volume":"19","author":"Matsuo","year":"2007","journal-title":"J Invasive Cardiol"},{"key":"10.1016\/j.carrev.2017.02.004_bb0280","first-page":"677","article-title":"Comparison of myocardial perfusion by distal protection before and after primary stenting for acute myocardial infarction: angiographic and clinical results of a randomized controlled trial","volume":"70","author":"Muramatsu","year":"2007","journal-title":"Catheter Cardiovasc Interv"},{"key":"10.1016\/j.carrev.2017.02.004_bb0285","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/j.amjcard.2006.08.038","article-title":"Protection of distal embolization in high-risk patients with acute ST-segment elevation myocardial infarction (PREMIAR)","volume":"99","author":"Cura","year":"2007","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.carrev.2017.02.004_bb0290","doi-asserted-by":"crossref","first-page":"1462","DOI":"10.1161\/CIRCULATIONAHA.105.545178","article-title":"Randomized evaluation of the effects of filter-based distal protection on myocardial perfusion and infarct size after primary percutaneous catheter intervention in myocardial infarction with and without ST-segment elevation","volume":"112","author":"Gick","year":"2005","journal-title":"Circulation"},{"key":"10.1016\/j.carrev.2017.02.004_bb0295","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1016\/j.amjcard.2006.11.037","article-title":"Safety and efficacy of the FilterWire EZ in acute ST-segment elevation myocardial infarction","volume":"99","author":"Guetta","year":"2007","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.carrev.2017.02.004_bb0300","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1016\/j.jacc.2007.10.047","article-title":"Randomized comparison of distal protection versus conventional treatment in primary percutaneous coronary intervention: the drug elution and distal protection in ST-elevation myocardial infarction (DEDICATION) trial","volume":"51","author":"Kelbaek","year":"2008","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.carrev.2017.02.004_bb0305","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1016\/j.jcin.2009.07.013","volume":"2","author":"Haeck","year":"2009","journal-title":"JACC Cardiovasc Interv"},{"key":"10.1016\/j.carrev.2017.02.004_bb0310","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1016\/j.amjcard.2010.04.014","article-title":"Impact of thrombectomy with EXPort catheter in infarct-related artery during primary percutaneous coronary intervention (EXPIRA trial) on cardiac death","volume":"106","author":"Sardella","year":"2010","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.carrev.2017.02.004_bb0315","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1186\/1471-2261-10-10","article-title":"Safety and efficacy of thrombectomy in patients undergoing primary percutaneous coronary intervention for acute ST elevation MI: a meta-analysis of randomized controlled trials","volume":"10","author":"Tamhane","year":"2010","journal-title":"BMC Cardiovasc Disord"},{"key":"10.1016\/j.carrev.2017.02.004_bb0320","doi-asserted-by":"crossref","first-page":"718","DOI":"10.1016\/j.jcin.2013.03.013","article-title":"Relationship between myocardial reperfusion, infarct size, and mortality: the INFUSE-AMI (intracoronary abciximab and aspiration thrombectomy in patients with large anterior myocardial infarction) trial","volume":"6","author":"Brener","year":"2013","journal-title":"JACC Cardiovasc Interv"},{"key":"10.1016\/j.carrev.2017.02.004_bb0325","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1056\/NEJMoa0706416","article-title":"Thrombus aspiration during primary percutaneous coronary intervention","volume":"358","author":"Svilaas","year":"2008","journal-title":"N Engl J Med"},{"key":"10.1016\/j.carrev.2017.02.004_bb0330","doi-asserted-by":"crossref","first-page":"1915","DOI":"10.1016\/S0140-6736(08)60833-8","article-title":"Cardiac death and reinfarction after 1 year in the Tthrombus Aaspiration during Ppercutaneous coronary intervention in Aacute myocardial infarction Sstudy (TAPAS): a 1-year follow-up study","volume":"371","author":"Vlaar","year":"2008","journal-title":"Lancet"},{"key":"10.1016\/j.carrev.2017.02.004_bb0335","doi-asserted-by":"crossref","first-page":"1587","DOI":"10.1056\/NEJMoa1308789","article-title":"Thrombus aspiration during ST-segment elevation myocardial infarction","volume":"369","author":"Frobert","year":"2013","journal-title":"N Engl J Med"},{"key":"10.1016\/j.carrev.2017.02.004_bb0340","doi-asserted-by":"crossref","first-page":"1389","DOI":"10.1056\/NEJMoa1415098","article-title":"Randomized trial of primary PCI with or without routine manual thrombectomy","volume":"372","author":"Jolly","year":"2015","journal-title":"N Engl J Med"},{"key":"10.1016\/j.carrev.2017.02.004_bb0345","doi-asserted-by":"crossref","first-page":"1891","DOI":"10.1093\/eurheartj\/ehw157","article-title":"Myocardial blush and microvascular reperfusion following manual thrombectomy during percutaneous coronary intervention for ST elevation myocardial infarction: insights from the TOTAL trial","volume":"37","author":"Sharma","year":"2016","journal-title":"Eur Heart J"},{"key":"10.1016\/j.carrev.2017.02.004_bb0350","first-page":"025371","article-title":"Thrombus aspiration in ST elevation myocardial infarction: an individual patient meta-analysis","volume":"9","author":"Jolly","year":"2016","journal-title":"Circulation"},{"key":"10.1016\/j.carrev.2017.02.004_bb0355","first-page":"04506","article-title":"Prospective, randomized, multicenter evaluation of a polyethylene terephthalate micronet mesh-covered stent (MGuard) in ST-segment elevation myocardial infarction: the MASTER trial","volume":"28","author":"Stone","year":"2012","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.carrev.2017.02.004_bb0360","first-page":"17","article-title":"Real world comparison of the MGuard stent versus the bare metal stent for ST elevation myocardial infarction (the REWARD-MI study)","volume":"85","author":"Fernandez-Cisnal","year":"2015","journal-title":"Catheter Cardiovasc Interv"},{"key":"10.1016\/j.carrev.2017.02.004_bb0365","doi-asserted-by":"crossref","first-page":"1485","DOI":"10.1016\/j.amjcard.2014.08.007","article-title":"Efficacy of an embolic protection stent as a function of delay to reperfusion in ST-segment elevation myocardial infarction (from the MASTER trial)","volume":"114","author":"Dudek","year":"2014","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.carrev.2017.02.004_bb0370","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1161\/01.CIR.76.1.142","article-title":"Thrombolysis in myocardial infarction (TIMI) trial, phase I: a comparison between intravenous tissue plasminogen activator and intravenous streptokinase. Clinical findings through hospital discharge","volume":"76","author":"Chesebro","year":"1987","journal-title":"Circulation"},{"key":"10.1016\/j.carrev.2017.02.004_bb0375","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1016\/S0140-6736(96)02514-7","article-title":"Early thrombolytic treatment in acute myocardial infarction: reappraisal of the golden hour","volume":"348","author":"Boersma","year":"1996","journal-title":"Lancet"},{"key":"10.1016\/j.carrev.2017.02.004_bb0380","doi-asserted-by":"crossref","first-page":"1451","DOI":"10.1016\/0735-1097(91)90630-R","article-title":"Coronary patency, infarct size and left ventricular function after thrombolytic therapy for acute myocardial infarction: results from the tissue plasminogen activator: Toronto (TPAT) placebo-controlled trial. TPAT study group","volume":"17","author":"Morgan","year":"1991","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.carrev.2017.02.004_bb0385","doi-asserted-by":"crossref","first-page":"1823","DOI":"10.1056\/NEJMoa054374","article-title":"Intracoronary streptokinase after primary percutaneous coronary intervention","volume":"356","author":"Sezer","year":"2007","journal-title":"N Engl J Med"},{"key":"10.1016\/j.carrev.2017.02.004_bb0390","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1016\/j.jacc.2009.04.083","article-title":"Effect of intracoronary streptokinase administered immediately after primary percutaneous coronary intervention on long-term left ventricular infarct size, volumes, and function","volume":"54","author":"Sezer","year":"2009","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.carrev.2017.02.004_bb0395","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/0026-2862(73)90069-1","article-title":"The role of blood flow in platelet adhesion, fibrin deposition, and formation of mural thrombi","volume":"5","author":"Baumgartner","year":"1973","journal-title":"Microvasc Res"},{"key":"10.1016\/j.carrev.2017.02.004_bb0400","doi-asserted-by":"crossref","first-page":"1134","DOI":"10.1172\/JCI114277","article-title":"Mechanisms of arterial thrombosis in nonparallel streamlines: platelet thrombi grow on the apex of stenotic severely injured vessel wall. Experimental study in the pig model","volume":"84","author":"Badimon","year":"1989","journal-title":"J Clin Invest"},{"key":"10.1016\/j.carrev.2017.02.004_bb0405","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1161\/01.ATV.10.2.306","article-title":"Dynamic monitoring of platelet deposition on severely damaged vessel wall in flowing blood. Effects of different stenoses on thrombus growth","volume":"10","author":"Lassila","year":"1990","journal-title":"Arteriosclerosis"},{"key":"10.1016\/j.carrev.2017.02.004_bb0410","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1016\/j.ahj.2011.12.007","article-title":"A high loading dose of clopidogrel reduces myocardial infarct size in patients undergoing primary percutaneous coronary intervention: a magnetic resonance imaging study","volume":"163","author":"Song","year":"2012","journal-title":"Am Heart J"},{"key":"10.1016\/j.carrev.2017.02.004_bb0415","first-page":"110","article-title":"Association of upstream clopidogrel administration and myocardial reperfusion assessed by cardiac magnetic resonance imaging in patients with ST-elevation myocardial infarction","volume":"3","author":"de Waha","year":"2014","journal-title":"Eur Heart J Acute Cardiovasc Care"},{"key":"10.1016\/j.carrev.2017.02.004_bb0420","doi-asserted-by":"crossref","first-page":"e964","DOI":"10.4244\/EIJV12I8A159","article-title":"Randomised trial to compare a protective effect of clopidogrel versus TIcagrelor on coronary microvascular injury in ST-segment elevation myocardial infarction (CV-TIME trial)","volume":"12","author":"Park","year":"2016","journal-title":"EuroIntervention"},{"key":"10.1016\/j.carrev.2017.02.004_bb0425","doi-asserted-by":"crossref","first-page":"003403","DOI":"10.1161\/JAHA.116.003403","article-title":"Infarct size following treatment with second- versus third-generation P2Y12 antagonists in patients with Multivessel coronary disease at ST-segment elevation myocardial infarction in the CvLPRIT study","volume":"5","author":"Khan","year":"2016","journal-title":"J Am Heart Assoc"},{"key":"10.1016\/j.carrev.2017.02.004_bb0430","doi-asserted-by":"crossref","first-page":"2078","DOI":"10.1161\/ATVBAHA.114.304002","article-title":"Chronic treatment with ticagrelor limits myocardial infarct size: an adenosine and cyclooxygenase-2-dependent effect","volume":"34","author":"Nanhwan","year":"2014","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.carrev.2017.02.004_bb0435","doi-asserted-by":"crossref","first-page":"2503","DOI":"10.1016\/j.jacc.2014.03.031","article-title":"Adenosine-mediated effects of TicagrelorEvidence and potential clinical relevance","volume":"63","author":"Cattaneo","year":"2014","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.carrev.2017.02.004_bb0440","doi-asserted-by":"crossref","first-page":"1805","DOI":"10.1161\/ATVBAHA.115.305655","article-title":"Ticagrelor protects the heart against reperfusion injury and improves remodeling after myocardial infarction","volume":"35","author":"Ye","year":"2015","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.carrev.2017.02.004_bb0445","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1016\/S0140-6736(09)62191-7","article-title":"Comparison of ticagrelor with clopidogrel in patients with a planned invasive strategy for acute coronary syndromes (PLATO): a randomised double-blind study","volume":"375","author":"Cannon","year":"2010","journal-title":"Lancet"},{"key":"10.1016\/j.carrev.2017.02.004_bb0450","doi-asserted-by":"crossref","first-page":"1130","DOI":"10.1160\/TH11-12-0867","article-title":"Prasugrel inhibits platelet-leukocyte interaction and reduces inflammatory markers in a model of endotoxic shock in the mouse","volume":"107","author":"Totani","year":"2012","journal-title":"Thromb Haemost"},{"key":"10.1016\/j.carrev.2017.02.004_bb0455","first-page":"1083","article-title":"Effect of bivalirudin compared with unfractionated heparin plus abciximab on infarct size and myocardial recovery after primary percutaneous coronary intervention: the horizons-AMI CMRI substudy","volume":"79","author":"Wohrle","year":"2012","journal-title":"Catheter Cardiovasc Interv"},{"key":"10.1016\/j.carrev.2017.02.004_bb0460","doi-asserted-by":"crossref","first-page":"2218","DOI":"10.1056\/NEJMoa0708191","article-title":"Bivalirudin during primary PCI in acute myocardial infarction","volume":"358","author":"Stone","year":"2008","journal-title":"N Engl J Med"},{"key":"10.1016\/j.carrev.2017.02.004_bb0465","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1016\/S0008-6363(97)00292-7","article-title":"The low molecular weight heparin, enoxaparin, limits infarct size at reperfusion in the dog","volume":"37","author":"Libersan","year":"1998","journal-title":"Cardiovasc Res"},{"key":"10.1016\/j.carrev.2017.02.004_bb0470","doi-asserted-by":"crossref","first-page":"1464","DOI":"10.1056\/NEJMoa055443","article-title":"Comparison of fondaparinux and enoxaparin in acute coronary syndromes","volume":"354","author":"Yusuf","year":"2006","journal-title":"N Engl J Med"},{"key":"10.1016\/j.carrev.2017.02.004_bb0475","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1161\/01.CIR.43.1.67","article-title":"Factors influencing infarct size following experimental coronary artery occlusions","volume":"43","author":"Maroko","year":"1971","journal-title":"Circulation"},{"key":"10.1016\/j.carrev.2017.02.004_bb0480","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1016\/0002-9149(79)90198-X","article-title":"Significance of spasm in the pathogenesis of ischemic heart disease","volume":"44","author":"Maseri","year":"1979","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.carrev.2017.02.004_bb0485","doi-asserted-by":"crossref","first-page":"2531","DOI":"10.1006\/jmcc.1998.0824","article-title":"Microvascular involvement in cardiac pathology","volume":"30","author":"Gavin","year":"1998","journal-title":"J Mol Cell Cardiol"},{"key":"10.1016\/j.carrev.2017.02.004_bb0490","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1016\/0002-9149(80)90064-8","article-title":"Protective effect of pretreatment with verapamil, nifedipine and propranolol on mitochondrial function in the ischemic and reperfused myocardium","volume":"46","author":"Nayler","year":"1980","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.carrev.2017.02.004_bb0495","doi-asserted-by":"crossref","first-page":"1882","DOI":"10.1038\/sj.bjp.0704646","article-title":"NCX4016 (NO-aspirin) reduces infarct size and suppresses arrhythmias following myocardial ischaemia\/reperfusion in pigs","volume":"135","author":"Wainwright","year":"2002","journal-title":"Br J Pharmacol"},{"key":"10.1016\/j.carrev.2017.02.004_bb0500","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1161\/01.RES.62.4.668","article-title":"Thromboxane synthetase inhibitors reduce infarct size by a platelet-dependent, aspirin-sensitive mechanism","volume":"62","author":"Mullane","year":"1988","journal-title":"Circ Res"},{"key":"10.1016\/j.carrev.2017.02.004_bb0505","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1007\/s10557-012-6436-7","article-title":"Two classes of anti-platelet drugs reduce anatomical infarct size in monkey hearts","volume":"27","author":"Yang","year":"2013","journal-title":"Cardiovasc Drugs Ther"},{"key":"10.1016\/j.carrev.2017.02.004_bb0510","doi-asserted-by":"crossref","first-page":"1457","DOI":"10.1016\/j.amjcard.2014.02.002","article-title":"Outcomes in patients with ST-segment elevation acute myocardial infarction treated with clopidogrel versus prasugrel (from the INFUSE-AMI trial)","volume":"113","author":"Brener","year":"2014","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.carrev.2017.02.004_bb0515","doi-asserted-by":"crossref","first-page":"2695","DOI":"10.1161\/01.CIR.98.24.2695","article-title":"Effect of glycoprotein IIb\/IIIa receptor blockade on recovery of coronary flow and left ventricular function after the placement of coronary-artery stents in acute myocardial infarction","volume":"98","author":"Neumann","year":"1998","journal-title":"Circulation"},{"key":"10.1016\/j.carrev.2017.02.004_bb0520","doi-asserted-by":"crossref","first-page":"1517","DOI":"10.1016\/j.jacc.2006.12.036","article-title":"Randomized early versus late abciximab in acute myocardial infarction treated with primary coronary intervention (RELAx-AMI trial)","volume":"49","author":"Maioli","year":"2007","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.carrev.2017.02.004_bb0525","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1016\/S0140-6736(08)61235-0","article-title":"Prehospital initiation of tirofiban in patients with ST-elevation myocardial infarction undergoing primary angioplasty (on-TIME 2): a multicentre, double-blind, randomised controlled trial","volume":"372","author":"Van't Hof","year":"2008","journal-title":"Lancet"},{"key":"10.1016\/j.carrev.2017.02.004_bb0530","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1161\/01.CIR.99.4.482","article-title":"Alpha-adrenergic blockade improves recovery of myocardial perfusion and function after coronary stenting in patients with acute myocardial infarction","volume":"99","author":"Gregorini","year":"1999","journal-title":"Circulation"},{"key":"10.1016\/j.carrev.2017.02.004_bb0535","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1016\/j.annemergmed.2014.07.010","article-title":"Efficacy and safety of out-of-hospital intravenous metoprolol administration in anterior ST-segment elevation acute myocardial infarction: insights from the METOCARD-CNIC trial","volume":"65","author":"Mateos","year":"2015","journal-title":"Ann Emerg Med"},{"key":"10.1016\/j.carrev.2017.02.004_bb0540","doi-asserted-by":"crossref","first-page":"2093","DOI":"10.1016\/j.jacc.2016.02.050","article-title":"Impact of the timing of metoprolol administration during STEMI on infarct size and ventricular function","volume":"67","author":"Garcia-Ruiz","year":"2016","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.carrev.2017.02.004_bb0545","doi-asserted-by":"crossref","first-page":"1622","DOI":"10.1016\/S0140-6736(05)67661-1","article-title":"Early intravenous then oral metoprolol in 45,852 patients with acute myocardial infarction: randomised placebo-controlled trial","volume":"366","author":"Chen","year":"2005","journal-title":"Lancet"},{"key":"10.1016\/j.carrev.2017.02.004_bb0550","doi-asserted-by":"crossref","first-page":"868","DOI":"10.1016\/0735-1097(91)90814-P","article-title":"Effect of intracoronary diltiazem on infarct size and regional myocardial function in the ischemic reperfused canine heart","volume":"18","author":"Higginson","year":"1991","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.carrev.2017.02.004_bb0555","doi-asserted-by":"crossref","first-page":"1255","DOI":"10.1093\/eurheartj\/ehu096","article-title":"Intravenous sodium nitrite in acute ST-elevation myocardial infarction: a randomized controlled trial (NIAMI)","volume":"35","author":"Siddiqi","year":"2014","journal-title":"Eur Heart J"},{"key":"10.1016\/j.carrev.2017.02.004_bb0560","doi-asserted-by":"crossref","first-page":"1657","DOI":"10.1001\/jama.297.15.joc70035","article-title":"Effect of tilarginine acetate in patients with acute myocardial infarction and cardiogenic shock: the TRIUMPH randomized controlled trial","volume":"297","author":"Alexander","year":"2007","journal-title":"JAMA"},{"key":"10.1016\/j.carrev.2017.02.004_bb0565","doi-asserted-by":"crossref","first-page":"1172","DOI":"10.1016\/S0735-1097(02)02115-0","article-title":"Direct vascular and cardioprotective effects of rosuvastatin, a new HMG-CoA reductase inhibitor","volume":"40","author":"Jones","year":"2002","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.carrev.2017.02.004_bb0570","doi-asserted-by":"crossref","first-page":"1129","DOI":"10.1161\/01.CIR.97.12.1129","article-title":"Upregulation of endothelial nitric oxide synthase by HMG CoA reductase inhibitors","volume":"97","author":"Laufs","year":"1998","journal-title":"Circulation"},{"key":"10.1016\/j.carrev.2017.02.004_bb0575","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1161\/01.RES.0000170229.49776.81","article-title":"HMG-CoA reductase inhibitors inhibit endothelial exocytosis and decrease myocardial infarct size","volume":"96","author":"Yamakuchi","year":"2005","journal-title":"Circ Res"},{"key":"10.1016\/j.carrev.2017.02.004_bb0580","first-page":"BR155","article-title":"Simvastatin reduces infarct size in a model of acute myocardial ischemia and reperfusion in the rat","volume":"9","author":"Wayman","year":"2003","journal-title":"Med Sci Monit"},{"key":"10.1016\/j.carrev.2017.02.004_bb0585","doi-asserted-by":"crossref","first-page":"2120","DOI":"10.1016\/S0735-1097(99)00440-4","article-title":"Pravastatin restored the infarct size-limiting effect of ischemic preconditioning blunted by hypercholesterolemia in the rabbit model of myocardial infarction","volume":"34","author":"Ueda","year":"1999","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.carrev.2017.02.004_bb0590","doi-asserted-by":"crossref","first-page":"1643","DOI":"10.1253\/circj.70.1643","article-title":"Early administration of fluvastatin, but not at the onset of ischemia or reperfusion, attenuates myocardial ischemia\u2013reperfusion injury through the nitric oxide pathway rather than its antioxidant property","volume":"70","author":"Matsuki","year":"2006","journal-title":"Circ J"},{"key":"10.1016\/j.carrev.2017.02.004_bb0595","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1038\/sj.bjp.0706862","article-title":"Pretreatment with simvastatin reduces myocardial no-reflow by opening mitochondrial K(ATP) channel","volume":"149","author":"Zhao","year":"2006","journal-title":"Br J Pharmacol"},{"key":"10.1016\/j.carrev.2017.02.004_bb0600","doi-asserted-by":"crossref","first-page":"2180","DOI":"10.1161\/01.CIR.0000037520.89770.5E","article-title":"Preprocedural statin medication reduces the extent of periprocedural non-Q-wave myocardial infarction","volume":"106","author":"Herrmann","year":"2002","journal-title":"Circulation"},{"key":"10.1016\/j.carrev.2017.02.004_bb0605","doi-asserted-by":"crossref","first-page":"1822","DOI":"10.1016\/j.ehj.2004.07.017","article-title":"Statin administration before percutaneous coronary intervention: impact on periprocedural myocardial infarction","volume":"25","author":"Briguori","year":"2004","journal-title":"Eur Heart J"},{"key":"10.1016\/j.carrev.2017.02.004_bb0610","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.amjcard.2004.03.021","article-title":"Effect of intracoronary adenosine infusion during coronary intervention on myocardial reperfusion injury in patients with acute myocardial infarction","volume":"94","author":"Claeys","year":"2004","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.carrev.2017.02.004_bb0615","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1161\/01.CIR.83.1.237","article-title":"Reduction of myocardial reperfusion injury by intravenous adenosine administered during the early reperfusion period","volume":"83","author":"Pitarys","year":"1991","journal-title":"Circulation"},{"key":"10.1016\/j.carrev.2017.02.004_bb0620","doi-asserted-by":"crossref","first-page":"808","DOI":"10.1016\/0002-8703(90)90196-5","article-title":"Intracoronary adenosine administration during reperfusion following 3hours of ischemia: effects on infarct size, ventricular function, and regional myocardial blood flow","volume":"120","author":"Babbitt","year":"1990","journal-title":"Am Heart J"},{"key":"10.1016\/j.carrev.2017.02.004_bb0625","doi-asserted-by":"crossref","first-page":"1775","DOI":"10.1016\/j.jacc.2005.02.061","article-title":"A randomized, double-blinded, placebo-controlled multicenter trial of adenosine as an adjunct to reperfusion in the treatment of acute myocardial infarction (AMISTAD-II)","volume":"45","author":"Ross","year":"2005","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.carrev.2017.02.004_bb0630","doi-asserted-by":"crossref","first-page":"2154","DOI":"10.1161\/01.CIR.101.18.2154","article-title":"Beneficial effects of intracoronary adenosine as an adjunct to primary angioplasty in acute myocardial infarction","volume":"101","author":"Marzilli","year":"2000","journal-title":"Circulation"},{"key":"10.1016\/j.carrev.2017.02.004_bb0635","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1161\/01.CIR.73.3.444","article-title":"Intracoronary papaverine: an ideal coronary vasodilator for studies of the coronary circulation in conscious humans","volume":"73","author":"Wilson","year":"1986","journal-title":"Circulation"},{"key":"10.1016\/j.carrev.2017.02.004_bb0640","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1016\/S0002-8703(96)90005-8","article-title":"Attenuation of the no-reflow phenomenon after coronary angioplasty for acute myocardial infarction with intracoronary papaverine","volume":"132","author":"Ishihara","year":"1996","journal-title":"Am Heart J"},{"key":"10.1016\/j.carrev.2017.02.004_bb0645","first-page":"305","article-title":"Resolution of refractory no-reflow with intracoronary epinephrine","volume":"57","author":"Skelding","year":"2002","journal-title":"Catheter Cardiovasc Interv"},{"key":"10.1016\/j.carrev.2017.02.004_bb0650","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1177\/1074248411405383","article-title":"Cardioprotection by ivabradine through heart rate reduction and beyond","volume":"16","author":"Heusch","year":"2011","journal-title":"J Cardiovasc Pharmacol Ther"},{"key":"10.1016\/j.carrev.2017.02.004_bb0655","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1093\/eurheartj\/ehi199","article-title":"Intense metabolic control by means of insulin in patients with diabetes mellitus and acute myocardial infarction (DIGAMI 2): effects on mortality and morbidity","volume":"26","author":"Malmberg","year":"2005","journal-title":"Eur Heart J"},{"key":"10.1016\/j.carrev.2017.02.004_bb0660","doi-asserted-by":"crossref","first-page":"2399","DOI":"10.1001\/jama.298.20.2399","article-title":"Glucose-insulin-potassium therapy in patients with ST-segment elevation myocardial infarction","volume":"298","author":"Diaz","year":"2007","journal-title":"JAMA"},{"key":"10.1016\/j.carrev.2017.02.004_bb0665","first-page":"e20","article-title":"A meta-analysis of glucose-insulin-potassium therapy for treatment of acute myocardial infarction","volume":"15","author":"Mamas","year":"2010","journal-title":"Exp Clin Cardiol"},{"key":"10.1016\/j.carrev.2017.02.004_bb0670","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.1161\/01.CIR.74.5.1124","article-title":"Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium","volume":"74","author":"Murry","year":"1986","journal-title":"Circulation"},{"key":"10.1016\/j.carrev.2017.02.004_bb0675","doi-asserted-by":"crossref","first-page":"2044","DOI":"10.1161\/01.CIR.82.6.2044","article-title":"Adaptation to ischemia during percutaneous transluminal coronary angioplasty. Clinical, hemodynamic, and metabolic features","volume":"82","author":"Deutsch","year":"1990","journal-title":"Circulation"},{"key":"10.1016\/j.carrev.2017.02.004_bb0680","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1016\/0140-6736(93)91819-8","article-title":"Preconditioning the human myocardium","volume":"342","author":"Yellon","year":"1993","journal-title":"Lancet"},{"key":"10.1016\/j.carrev.2017.02.004_bb0685","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1007\/s10741-016-9560-9","article-title":"Remote ischaemic conditioning and remodelling following myocardial infarction: current evidence and future perspectives","volume":"21","author":"Vanezis","year":"2016","journal-title":"Heart Fail Rev"},{"key":"10.1016\/j.carrev.2017.02.004_bb0690","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1016\/S0140-6736(09)62001-8","article-title":"Remote ischaemic conditioning before hospital admission, as a complement to angioplasty, and effect on myocardial salvage in patients with acute myocardial infarction: a randomised trial","volume":"375","author":"Botker","year":"2010","journal-title":"Lancet"},{"key":"10.1016\/j.carrev.2017.02.004_bb0695","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.jcin.2009.10.015","article-title":"Cardioprotective role of remote ischemic periconditioning in primary percutaneous coronary intervention: enhancement by opioid action","volume":"3","author":"Rentoukas","year":"2010","journal-title":"JACC Cardiovasc Interv"},{"key":"10.1016\/j.carrev.2017.02.004_bb0700","doi-asserted-by":"crossref","first-page":"015","DOI":"10.1007\/s00395-015-0467-8","article-title":"Remote ischemic conditioning and cardioprotection: a systematic review and meta-analysis of randomized clinical trials","volume":"110","author":"Le Page","year":"2015","journal-title":"Basic Res Cardiol"},{"key":"10.1016\/j.carrev.2017.02.004_bb0705","doi-asserted-by":"crossref","first-page":"1408","DOI":"10.1056\/NEJMoa1413534","article-title":"Remote ischemic preconditioning and outcomes of cardiac surgery","volume":"373","author":"Hausenloy","year":"2015","journal-title":"N Engl J Med"},{"key":"10.1016\/j.carrev.2017.02.004_bb0710","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1161\/CIRCINTERVENTIONS.113.000948","article-title":"Remote ischemic postconditioning during percutaneous coronary interventions: remote ischemic postconditioning-percutaneous coronary intervention randomized trial","volume":"7","author":"Lavi","year":"2014","journal-title":"Circ Cardiovasc Interv"},{"key":"10.1016\/j.carrev.2017.02.004_bb0715","doi-asserted-by":"crossref","DOI":"10.1002\/clc.22668","article-title":"Long-term outcome following remote ischemic postconditioning during percutaneous coronary interventions-the RIP-PCI trial long-term follow-up","author":"Lavi","year":"2017","journal-title":"Clin Cardiol"},{"key":"10.1016\/j.carrev.2017.02.004_bb0720","doi-asserted-by":"crossref","first-page":"i5599","DOI":"10.1136\/bmj.i5599","article-title":"Effects of ischaemic conditioning on major clinical outcomes in people undergoing invasive procedures: systematic review and meta-analysis","volume":"355","author":"Sukkar","year":"2016","journal-title":"BMJ"},{"key":"10.1016\/j.carrev.2017.02.004_bb0725","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1152\/ajpendo.00577.2014","article-title":"AdipoRon, the first orally active adiponectin receptor activator, attenuates postischemic myocardial apoptosis through both AMPK-mediated and AMPK-independent signalings","volume":"309","author":"Zhang","year":"2015","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"10.1016\/j.carrev.2017.02.004_bb0730","first-page":"253","article-title":"The cardio-protective signaling and mechanisms of adiponectin","volume":"2","author":"Nanayakkara","year":"2012","journal-title":"Am J Cardiovasc Dis"},{"key":"10.1016\/j.carrev.2017.02.004_bb0735","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1161\/HYPERTENSIONAHA.113.02902","article-title":"Aliskiren reduces myocardial ischemia\u2013reperfusion injury by a bradykinin B2 receptor- and angiotensin AT2 receptor-mediated mechanism","volume":"63","author":"Koid","year":"2014","journal-title":"Hypertension"},{"key":"10.1016\/j.carrev.2017.02.004_bb0740","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0081505","article-title":"Bradykinin preconditioning improves therapeutic potential of human endothelial progenitor cells in infarcted myocardium","volume":"8","author":"Sheng","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.carrev.2017.02.004_bb0745","doi-asserted-by":"crossref","first-page":"013","DOI":"10.1007\/s00395-013-0337-1","article-title":"Protection through postconditioning or a mitochondria-targeted S-nitrosothiol is unaffected by cardiomyocyte-selective ablation of protein kinase G","volume":"108","author":"Methner","year":"2013","journal-title":"Basic Res Cardiol"},{"key":"10.1016\/j.carrev.2017.02.004_bb0750","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1007\/s10557-014-6527-8","article-title":"Capsaicin-induced cardioprotection. Is hypothermia or the salvage kinase pathway involved?","volume":"28","author":"Dow","year":"2014","journal-title":"Cardiovasc Drugs Ther"},{"key":"10.1016\/j.carrev.2017.02.004_bb0755","doi-asserted-by":"crossref","first-page":"18965","DOI":"10.1074\/jbc.M112.357939","article-title":"CTRP9 protein protects against myocardial injury following ischemia\u2013reperfusion through AMP-activated protein kinase (AMPK)-dependent mechanism","volume":"287","author":"Kambara","year":"2012","journal-title":"J Biol Chem"},{"key":"10.1016\/j.carrev.2017.02.004_bb0760","doi-asserted-by":"crossref","first-page":"1321","DOI":"10.1073\/pnas.0308185100","article-title":"Reduction of ischemia and reperfusion-induced myocardial damage by cytochrome P450 inhibitors","volume":"101","author":"Granville","year":"2004","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.carrev.2017.02.004_bb0765","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1152\/ajpheart.00073.2010","article-title":"Dark chocolate receptors: epicatechin-induced cardiac protection is dependent on delta-opioid receptor stimulation","volume":"299","author":"Panneerselvam","year":"2010","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"10.1016\/j.carrev.2017.02.004_bb0770","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/j.ijcard.2014.05.009","article-title":"Intravenous (\u2212)-epicatechin reduces myocardial ischemic injury by protecting mitochondrial function","volume":"175","author":"Yamazaki","year":"2014","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.carrev.2017.02.004_bb0775","doi-asserted-by":"crossref","first-page":"1557","DOI":"10.1253\/circj.CJ-14-1171","article-title":"Renal nerve-mediated erythropoietin release confers cardioprotection during remote ischemic preconditioning","volume":"79","author":"Oba","year":"2015","journal-title":"Circ J"},{"key":"10.1016\/j.carrev.2017.02.004_bb0780","first-page":"105","article-title":"Amelioration of myocardial ischemia\/reperfusion injury by leptin pretreatment and ischemic preconditioning in mouse","volume":"22","author":"Xu","year":"2010","journal-title":"Zhongguo Wei Zhong Bing Ji Jiu Yi Xue"},{"key":"10.1016\/j.carrev.2017.02.004_bb0785","first-page":"79","article-title":"Myocardial protection by preconditioning. Experimental and clinical significance","volume":"85","author":"Strasser","year":"1996","journal-title":"Z Kardiol"},{"key":"10.1016\/j.carrev.2017.02.004_bb0790","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1016\/j.jss.2014.01.038","article-title":"Novel functional role of heat shock protein 90 in protein kinase C-mediated ischemic postconditioning","volume":"189","author":"Zhong","year":"2014","journal-title":"J Surg Res"},{"key":"10.1016\/j.carrev.2017.02.004_bb0795","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1016\/j.vph.2006.04.002","article-title":"Cardioprotective effect of resvaratrol pretreatment on myocardial ischemia\u2013reperfusion induced injury in rats","volume":"45","author":"Shen","year":"2006","journal-title":"Vasc Pharmacol"},{"key":"10.1016\/j.carrev.2017.02.004_bb0800","doi-asserted-by":"crossref","first-page":"2651","DOI":"10.1111\/j.1582-4934.2008.00319.x","article-title":"Sildenafil-mediated neovascularization and protection against myocardial ischaemia reperfusion injury in rats: role of VEGF\/angiopoietin-1","volume":"12","author":"Koneru","year":"2008","journal-title":"J Cell Mol Med"},{"key":"10.1016\/j.carrev.2017.02.004_bb0805","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1007\/s10557-014-6559-0","article-title":"Tadalafil prevents acute heart failure with reduced ejection fraction in mice","volume":"28","author":"Salloum","year":"2014","journal-title":"Cardiovasc Drugs Ther"},{"key":"10.1016\/j.carrev.2017.02.004_bb0810","doi-asserted-by":"crossref","first-page":"1014","DOI":"10.1016\/j.jacc.2009.06.010","article-title":"Intracoronary injection of in situ forming alginate hydrogel reverses left ventricular remodeling after myocardial infarction in swine","volume":"54","author":"Leor","year":"2009","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.carrev.2017.02.004_bb0815","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1016\/j.jacc.2016.05.053","article-title":"Bioabsorbable intracoronary matrix for prevention of ventricular remodeling after myocardial infarction","volume":"68","author":"Rao","year":"2016","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.carrev.2017.02.004_bb0820","first-page":"135","article-title":"Combination therapy reduces the incidence of no-reflow after primary per-cutaneous coronary intervention in patients with ST-segment elevation acute myocardial infarction","volume":"12","author":"Zhou","year":"2015","journal-title":"J Geriatr Cardiol"}],"container-title":["Cardiovascular Revascularization Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1553838917300192?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1553838917300192?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T10:12:04Z","timestamp":1761559924000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1553838917300192"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,7]]},"references-count":164,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2017,7]]}},"alternative-id":["S1553838917300192"],"URL":"https:\/\/doi.org\/10.1016\/j.carrev.2017.02.004","relation":{},"ISSN":["1553-8389"],"issn-type":[{"value":"1553-8389","type":"print"}],"subject":[],"published":{"date-parts":[[2017,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A review of strategies for infarct size reduction during acute myocardial infarction","name":"articletitle","label":"Article Title"},{"value":"Cardiovascular Revascularization Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.carrev.2017.02.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}