{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,6]],"date-time":"2026-11-06T01:54:16Z","timestamp":1793930056064,"version":"4.8.0"},"reference-count":31,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100012367","name":"MedStar Health Research Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100012367","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cardiovascular Revascularization Medicine"],"published-print":{"date-parts":[[2024,12]]},"DOI":"10.1016\/j.carrev.2024.05.020","type":"journal-article","created":{"date-parts":[[2024,5,11]],"date-time":"2024-05-11T15:48:19Z","timestamp":1715442499000},"page":"30-34","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"special_numbering":"C","title":["Coronary microvascular dysfunction and inflammation: Insights from the Coronary Microvascular Disease Registry"],"prefix":"10.1016","volume":"69","author":[{"given":"Ilan","family":"Merdler","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kalyan R.","family":"Chitturi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abhishek","family":"Chaturvedi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matteo","family":"Cellamare","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sevket Tolga","family":"Ozturk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vaishnavi","family":"Sawant","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Itsik","family":"Ben-Dor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ron","family":"Waksman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian C.","family":"Case","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hayder D.","family":"Hashim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.carrev.2024.05.020_bb0005","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.atherosclerosis.2022.11.009","article-title":"Ischemia and no obstructive coronary arteries (INOCA): a narrative review","volume":"363","author":"Mehta","year":"2022","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.carrev.2024.05.020_bb0010","doi-asserted-by":"crossref","first-page":"13471","DOI":"10.3390\/ijms222413471","article-title":"Inflammation in coronary microvascular dysfunction","volume":"22","author":"Sagris","year":"2021","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.carrev.2024.05.020_bb0015","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1016\/j.cjca.2017.12.005","article-title":"Diabetes, hypertension, and cardiovascular disease: clinical insights and vascular mechanisms","volume":"34","author":"Petrie","year":"2018","journal-title":"Can J Cardiol"},{"key":"10.1016\/j.carrev.2024.05.020_bb0020","doi-asserted-by":"crossref","DOI":"10.1016\/j.ajpc.2020.100130","article-title":"Inflammation and cardiovascular disease: from mechanisms to therapeutics","volume":"4","author":"Alfaddagh","year":"2020","journal-title":"Am J Prev Cardiol"},{"key":"10.1016\/j.carrev.2024.05.020_bb0025","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1038\/s41573-021-00198-1","article-title":"Targeting inflammation in atherosclerosis \u2014 from experimental insights to the clinic","volume":"20","author":"Soehnlein","year":"2021","journal-title":"Nat Rev Drug Discov"},{"key":"10.1016\/j.carrev.2024.05.020_bb0030","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1007\/s00395-008-0733-0","article-title":"The role of inflammatory cytokines in endothelial dysfunction","volume":"103","author":"Zhang","year":"2008","journal-title":"Basic Res Cardiol"},{"key":"10.1016\/j.carrev.2024.05.020_bb0035","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1136\/heartjnl-2021-320718","article-title":"Invasive coronary physiology in patients with angina and non-obstructive coronary artery disease: a consensus document from the coronary microvascular dysfunction workstream of the British Heart Foundation\/National Institute for Health Research Partnership","volume":"109","author":"Perera","year":"2023","journal-title":"Heart"},{"key":"10.1016\/j.carrev.2024.05.020_bb0040","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1253\/circj.CJ-15-0201","article-title":"Coronary functional tests in the catheterization laboratory - pathophysiological and clinical relevance","volume":"79","author":"Niccoli","year":"2015","journal-title":"Circ J"},{"key":"10.1016\/j.carrev.2024.05.020_bb0045","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/j.carrev.2021.10.017","article-title":"Elevated NLR and increased coronary mortality \u2013 causative, or just an association?","volume":"34","author":"Shurmur","year":"2022","journal-title":"Cardiovasc Revasc Med"},{"key":"10.1016\/j.carrev.2024.05.020_bb0050","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1038\/s41598-020-79431-7","article-title":"Neutrophil-to-lymphocyte ratio and mortality in the United States general population","volume":"11","author":"Song","year":"2021","journal-title":"Sci Rep"},{"key":"10.1016\/j.carrev.2024.05.020_bb0055","doi-asserted-by":"crossref","first-page":"4687","DOI":"10.2147\/JIR.S325229","article-title":"Relationship between the eosinophil\/monocyte ratio and prognosis in decompensated heart failure: a retrospective study","volume":"14","author":"Chen","year":"2021","journal-title":"J Inflamm Res"},{"key":"10.1016\/j.carrev.2024.05.020_bb0060","doi-asserted-by":"crossref","first-page":"9119","DOI":"10.3390\/ijms22179119","article-title":"Nature versus number: monocytes in cardiovascular disease","volume":"22","author":"Williams","year":"2021","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.carrev.2024.05.020_bb0065","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1186\/s12944-022-01638-6","article-title":"Monocyte-to-high-density lipoprotein-cholesterol ratio (MHR) and the risk of all-cause and cardiovascular mortality: a nationwide cohort study in the United States","volume":"21","author":"Jiang","year":"2022","journal-title":"Lipids Health Dis"},{"key":"10.1016\/j.carrev.2024.05.020_bb0070","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.amjcard.2023.07.159","article-title":"Understanding patient characteristics and coronary microvasculature: early insights from the Coronary Microvascular Disease Registry","volume":"205","author":"Case","year":"2023","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.carrev.2024.05.020_bb0075","series-title":"StatPearls [Internet]","article-title":"Coronary artery disease. [Updated 2023 Aug 17]","author":"Shahjehan","year":"2023"},{"key":"10.1016\/j.carrev.2024.05.020_bb0080","first-page":"2880","article-title":"Coronary microvascular dysfunction. J","volume":"9","author":"Vancheri","year":"2020","journal-title":"Clin Med"},{"key":"10.1016\/j.carrev.2024.05.020_bb0085","doi-asserted-by":"crossref","first-page":"8118","DOI":"10.3390\/ijms21218118","article-title":"Ischemic heart disease pathophysiology paradigms overview: from plaque activation to microvascular dysfunction","volume":"21","author":"Severino","year":"2020","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.carrev.2024.05.020_bb0090","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCINTERVENTIONS.122.012568","article-title":"Coronary microvascular disease in contemporary clinical practice","volume":"16","author":"Smilowitz","year":"2023","journal-title":"Circ Cardiovasc Interv"},{"key":"10.1016\/j.carrev.2024.05.020_bb0095","doi-asserted-by":"crossref","first-page":"1799","DOI":"10.1093\/eurheartj\/ehw018","article-title":"Coronary microvascular dysfunction in chronic inflammatory rheumatoid diseases","volume":"37","author":"Faccini","year":"2016","journal-title":"Eur Heart J"},{"key":"10.1016\/j.carrev.2024.05.020_bb0100","doi-asserted-by":"crossref","first-page":"81","DOI":"10.14336\/AD.2015.0803","article-title":"Chronic inflammatory diseases and endothelial dysfunction","volume":"7","author":"Castellon","year":"2016","journal-title":"Aging Dis"},{"key":"10.1016\/j.carrev.2024.05.020_bb0105","doi-asserted-by":"crossref","first-page":"1126","DOI":"10.1089\/ars.2012.5149","article-title":"Reactive oxygen species in inflammation and tissue injury","volume":"20","author":"Mittal","year":"2014","journal-title":"Antioxid Redox Signal"},{"key":"10.1016\/j.carrev.2024.05.020_bb0110","doi-asserted-by":"crossref","first-page":"3636","DOI":"10.3390\/ijms23073636","article-title":"Neutrophil to lymphocyte ratio: an emerging marker of the relationships between the immune system and diseases","volume":"23","author":"Buonacera","year":"2022","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.carrev.2024.05.020_bb0115","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.carrev.2021.01.027","article-title":"Prognostic role of neutrophil-to-lymphocyte ratio in patients with ST-elevation myocardial infarction undergoing to pharmaco-invasive strategy","volume":"34","author":"Tavares","year":"2022","journal-title":"Cardiovasc Revasc Med"},{"key":"10.1016\/j.carrev.2024.05.020_bb0120","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1536\/ihj.15-346","article-title":"Inflammatory biomarkers and atherosclerosis","volume":"57","author":"Soeki","year":"2016","journal-title":"Int Heart J"},{"key":"10.1016\/j.carrev.2024.05.020_bb0125","doi-asserted-by":"crossref","first-page":"4998","DOI":"10.3390\/ijms23094998","article-title":"Novel biomarkers of atherosclerotic vascular disease\u2014latest insights in the research field","volume":"23","author":"Adam","year":"2022","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.carrev.2024.05.020_bb0130","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1186\/s12872-021-02236-7","article-title":"Accuracy of neutrophil to lymphocyte and monocyte to lymphocyte ratios as new inflammatory markers in acute coronary syndrome","volume":"21","author":"Shumilah","year":"2021","journal-title":"BMC Cardiovasc Disord"},{"key":"10.1016\/j.carrev.2024.05.020_bb0135","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1093\/cvr\/cvaa006","article-title":"Treatment of coronary microvascular dysfunction","volume":"116","author":"Bairey Merz","year":"2020","journal-title":"Cardiovasc Res"},{"key":"10.1016\/j.carrev.2024.05.020_bb0140","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1038\/s41569-021-00668-4","article-title":"Therapeutic strategies targeting inflammation and immunity in atherosclerosis: how to proceed?","volume":"19","author":"Engelen","year":"2022","journal-title":"Nat Rev Cardiol"},{"key":"10.1016\/j.carrev.2024.05.020_bb0145","doi-asserted-by":"crossref","first-page":"1264","DOI":"10.1016\/j.jacc.2023.06.044","article-title":"Comprehensive management of ANOCA, part 2\u2014program development, treatment, and research initiatives","volume":"82","author":"Smilowitz","year":"2023","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.carrev.2024.05.020_bb0150","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.1161\/CIRCULATIONAHA.116.024534","article-title":"Ischemia and no obstructive coronary artery disease (INOCA): developing evidence-based therapies and research agenda for the next decade","volume":"135","author":"Bairey Merz","year":"2017","journal-title":"Circulation"},{"key":"10.1016\/j.carrev.2024.05.020_bb0155","first-page":"46","article-title":"Assessing cardiovascular infection and inflammation with FDG-PET","volume":"11","author":"Martineau","year":"2021","journal-title":"Am J Nucl Med Mol Imaging"}],"container-title":["Cardiovascular Revascularization Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1553838924004883?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1553838924004883?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,12,10]],"date-time":"2024-12-10T00:29:16Z","timestamp":1733790556000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1553838924004883"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12]]},"references-count":31,"alternative-id":["S1553838924004883"],"URL":"https:\/\/doi.org\/10.1016\/j.carrev.2024.05.020","relation":{},"ISSN":["1553-8389"],"issn-type":[{"value":"1553-8389","type":"print"}],"subject":[],"published":{"date-parts":[[2024,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Coronary microvascular dysfunction and inflammation: Insights from the Coronary Microvascular Disease Registry","name":"articletitle","label":"Article Title"},{"value":"Cardiovascular Revascularization Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.carrev.2024.05.020","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}