{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T22:30:20Z","timestamp":1793831420607,"version":"4.6.1"},"reference-count":40,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cardiovascular Revascularization Medicine"],"published-print":{"date-parts":[[2025,2]]},"DOI":"10.1016\/j.carrev.2025.01.012","type":"journal-article","created":{"date-parts":[[2025,1,27]],"date-time":"2025-01-27T12:21:15Z","timestamp":1737980475000},"page":"11-15","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"special_numbering":"C","title":["Coronary microvascular dysfunction endotypes: IMR tips and tricks"],"prefix":"10.1016","volume":"71","author":[{"given":"Beni Rai","family":"Verma","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason","family":"Galo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kalyan R.","family":"Chitturi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abhishek","family":"Chaturvedi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hayder D.","family":"Hashim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian C.","family":"Case","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"7","key":"10.1016\/j.carrev.2025.01.012_bb0005","doi-asserted-by":"crossref","first-page":"e023207","DOI":"10.1161\/JAHA.121.023207","article-title":"Prevalence of coronary microvascular disease and coronary vasospasm in patients with nonobstructive coronary artery disease: systematic review and meta-analysis","volume":"11","author":"Mileva","year":"2022","journal-title":"J Am Heart Assoc"},{"issue":"13","key":"10.1016\/j.carrev.2025.01.012_bb0010","doi-asserted-by":"crossref","first-page":"1352","DOI":"10.1016\/j.jacc.2021.07.042","article-title":"Coronary microvascular dysfunction across the spectrum of cardiovascular diseases: JACC state-of-the-art review","volume":"78","author":"Del Buono","year":"2021","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.carrev.2025.01.012_bb0015","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.carrev.2024.03.026","article-title":"From chest pain to coronary functional testing: clinical and economic impact of coronary microvascular dysfunction","volume":"66","author":"Merdler","year":"2024","journal-title":"Cardiovasc Revasc Med"},{"issue":"19","key":"10.1016\/j.carrev.2025.01.012_bb0020","doi-asserted-by":"crossref","first-page":"2349","DOI":"10.1016\/j.jacc.2017.09.016","article-title":"Sex-related differences in vasomotor function in patients with angina and unobstructed coronary arteries","volume":"70","author":"Aziz","year":"2017","journal-title":"J Am Coll Cardiol"},{"issue":"24","key":"10.1016\/j.carrev.2025.01.012_bb0025","doi-asserted-by":"crossref","first-page":"2518","DOI":"10.1161\/CIRCULATIONAHA.113.008507","article-title":"Effects of sex on coronary microvascular dysfunction and cardiac outcomes","volume":"129","author":"Murthy","year":"2014","journal-title":"Circulation"},{"key":"10.1016\/j.carrev.2025.01.012_bb0030","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.ijcard.2017.08.068","article-title":"International standardization of diagnostic criteria for microvascular angina","volume":"250","author":"Ong","year":"2018","journal-title":"Int J Cardiol"},{"issue":"12","key":"10.1016\/j.carrev.2025.01.012_bb0035","doi-asserted-by":"crossref","first-page":"1245","DOI":"10.1016\/j.jacc.2023.06.043","article-title":"Comprehensive management of ANOCA, part 1-definition, patient population, and diagnosis: JACC state-of-the-art review","volume":"82","author":"Samuels","year":"2023","journal-title":"J Am Coll Cardiol"},{"issue":"4","key":"10.1016\/j.carrev.2025.01.012_bb0040","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1093\/cvr\/cvaa003","article-title":"ESC Working Group on Coronary Pathophysiology and Microcirculation position paper on \u2018coronary microvascular dysfunction in cardiovascular disease\u2019","volume":"116","author":"Padro","year":"2020","journal-title":"Cardiovasc Res"},{"key":"10.1016\/j.carrev.2025.01.012_bb0045","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.carrev.2024.05.020","article-title":"Coronary microvascular dysfunction and inflammation: insights from the Coronary Microvascular Disease Registry","volume":"69","author":"Merdler","year":"2024","journal-title":"Cardiovasc Revasc Med"},{"issue":"9","key":"10.1016\/j.carrev.2025.01.012_bb0050","doi-asserted-by":"crossref","first-page":"719","DOI":"10.4244\/EIJ-D-22-00043","article-title":"Prognostic value of structural and functional coronary microvascular dysfunction in patients with non-obstructive coronary artery disease; from the multicentre international ILIAS registry","volume":"18","author":"Boerhout","year":"2022","journal-title":"EuroIntervention"},{"issue":"22","key":"10.1016\/j.carrev.2025.01.012_bb0055","doi-asserted-by":"crossref","first-page":"1805","DOI":"10.1161\/CIRCULATIONAHA.119.041595","article-title":"Coronary microvascular dysfunction is associated with myocardial ischemia and abnormal coronary perfusion during exercise","volume":"140","author":"Rahman","year":"2019","journal-title":"Circulation"},{"issue":"7","key":"10.1016\/j.carrev.2025.01.012_bb0060","first-page":"101934","article-title":"A systematic approach to the evaluation of the coronary microcirculation using bolus thermodilution: CATH CMD","volume":"3","author":"Collet","year":"2024","journal-title":"J Soc Cardiovasc Angiogr Interv"},{"issue":"21","key":"10.1016\/j.carrev.2025.01.012_bb0065","doi-asserted-by":"crossref","first-page":"2625","DOI":"10.1016\/j.jacc.2018.09.042","article-title":"Coronary microvascular disease pathogenic mechanisms and therapeutic options: JACC state-of-the-art review","volume":"72","author":"Taqueti","year":"2018","journal-title":"J Am Coll Cardiol"},{"issue":"25","key":"10.1016\/j.carrev.2025.01.012_bb0070","doi-asserted-by":"crossref","first-page":"3129","DOI":"10.1161\/01.CIR.0000080700.98607.D1","article-title":"Novel index for invasively assessing the coronary microcirculation","volume":"107","author":"Fearon","year":"2003","journal-title":"Circulation"},{"key":"10.1016\/j.carrev.2025.01.012_bb0075","first-page":"1","article-title":"2024 ESC Guidelines for the management of chronic coronary syndromes","author":"Vrints","year":"2024","journal-title":"Eur Heart J"},{"issue":"17","key":"10.1016\/j.carrev.2025.01.012_bb0080","doi-asserted-by":"crossref","first-page":"2003","DOI":"10.1161\/hc4201.099223","article-title":"Coronary thermodilution to assess flow reserve: experimental validation","volume":"104","author":"De Bruyne","year":"2001","journal-title":"Circulation"},{"issue":"5","key":"10.1016\/j.carrev.2025.01.012_bb0085","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1016\/j.jacc.2007.08.062","article-title":"Predictive value of the index of microcirculatory resistance in patients with ST-segment elevation myocardial infarction","volume":"51","author":"Fearon","year":"2008","journal-title":"J Am Coll Cardiol"},{"issue":"5","key":"10.1016\/j.carrev.2025.01.012_bb0090","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1016\/j.jcmg.2018.02.018","article-title":"Index of microcirculatory resistance as a tool to characterize microvascular obstruction and to predict infarct size regression in patients with STEMI undergoing primary PCI","volume":"12","author":"De Maria","year":"2019","journal-title":"JACC Cardiovasc Imaging"},{"issue":"2","key":"10.1016\/j.carrev.2025.01.012_bb0095","doi-asserted-by":"crossref","first-page":"e155","DOI":"10.4244\/EIJ-D-22-00772","article-title":"Reproducibility of bolus versus continuous thermodilution for assessment of coronary microvascular function in patients with ANOCA","volume":"19","author":"Gallinoro","year":"2023","journal-title":"EuroIntervention"},{"key":"10.1016\/j.carrev.2025.01.012_bb0100","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1016\/j.carrev.2023.10.003","article-title":"Angiography-based assessment of coronary microvascular function: first US report of IMRangio","volume":"60","author":"Ha","year":"2024","journal-title":"Cardiovasc Revasc Med"},{"issue":"15","key":"10.1016\/j.carrev.2025.01.012_bb0105","doi-asserted-by":"crossref","first-page":"1541","DOI":"10.1016\/j.jacc.2021.08.017","article-title":"Microvascular resistance Reserve for Assessment of coronary microvascular function: JACC technology corner","volume":"78","author":"De Bruyne","year":"2021","journal-title":"J Am Coll Cardiol"},{"issue":"1","key":"10.1016\/j.carrev.2025.01.012_bb0110","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.amjcard.2017.09.012","article-title":"Doppler versus thermodilution-derived coronary microvascular resistance to predict coronary microvascular dysfunction in patients with acute myocardial infarction or stable angina pectoris","volume":"121","author":"Williams","year":"2018","journal-title":"Am J Cardiol"},{"issue":"1","key":"10.1016\/j.carrev.2025.01.012_bb0115","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.jcin.2012.08.019","article-title":"Calculation of the index of microcirculatory resistance without coronary wedge pressure measurement in the presence of epicardial stenosis","volume":"6","author":"Yong","year":"2013","journal-title":"JACC Cardiovasc Interv"},{"issue":"20","key":"10.1016\/j.carrev.2025.01.012_bb0120","doi-asserted-by":"crossref","first-page":"2538","DOI":"10.1016\/j.jacc.2020.03.051","article-title":"Physiological stratification of patients with angina due to coronary microvascular dysfunction","volume":"75","author":"Rahman","year":"2020","journal-title":"J Am Coll Cardiol"},{"issue":"10","key":"10.1016\/j.carrev.2025.01.012_bb0125","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1016\/j.cardfail.2019.08.010","article-title":"Coronary microvascular dysfunction and clinical outcomes in patients with heart failure with preserved ejection fraction","volume":"25","author":"Allan","year":"2019","journal-title":"J Card Fail"},{"issue":"10","key":"10.1016\/j.carrev.2025.01.012_bb0130","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1093\/eurheartj\/ehx721","article-title":"Coronary microvascular dysfunction and future risk of heart failure with preserved ejection fraction","volume":"39","author":"Taqueti","year":"2018","journal-title":"Eur Heart J"},{"issue":"5","key":"10.1016\/j.carrev.2025.01.012_bb0135","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1016\/j.jacc.2005.10.050","article-title":"Relevance of coronary microvascular flow impairment to long-term remodeling and systolic dysfunction in hypertrophic cardiomyopathy","volume":"47","author":"Olivotto","year":"2006","journal-title":"J Am Coll Cardiol"},{"issue":"9","key":"10.1016\/j.carrev.2025.01.012_bb0140","doi-asserted-by":"crossref","first-page":"e007889","DOI":"10.1161\/CIRCINTERVENTIONS.119.007889","article-title":"Prognostic value of coronary microvascular function measured immediately after percutaneous coronary intervention in stable coronary artery disease: an international multicenter study","volume":"12","author":"Nishi","year":"2019","journal-title":"Circ Cardiovasc Interv"},{"issue":"11","key":"10.1016\/j.carrev.2025.01.012_bb0145","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.1016\/j.jacc.2007.11.059","article-title":"Direct stenting for stable angina pectoris is associated with reduced periprocedural microcirculatory injury compared with stenting after pre-dilation","volume":"51","author":"Cuisset","year":"2008","journal-title":"J Am Coll Cardiol"},{"issue":"5","key":"10.1016\/j.carrev.2025.01.012_bb0150","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.117.007743","article-title":"Prognostic value of early postoperative troponin T in patients undergoing coronary artery bypass grafting","volume":"7","author":"Gahl","year":"2018","journal-title":"J Am Heart Assoc"},{"issue":"6","key":"10.1016\/j.carrev.2025.01.012_bb0155","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1111\/j.1475-097X.2009.00893.x","article-title":"Long-term prognostic role of coronary flow velocity reserve in patients with aortic valve stenosis \u2014 insights from the SZEGED study","volume":"29","author":"Nemes","year":"2009","journal-title":"Clin Physiol Funct Imaging"},{"issue":"4","key":"10.1016\/j.carrev.2025.01.012_bb0160","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1016\/j.jchf.2014.03.009","article-title":"Coronary microvascular dysfunction is related to abnormalities in myocardial structure and function in cardiac amyloidosis","volume":"2","author":"Dorbala","year":"2014","journal-title":"JACC Heart Fail"},{"key":"10.1016\/j.carrev.2025.01.012_bb0165","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.atherosclerosis.2017.05.005","article-title":"Coronary flow reserve is reduced in sarcoidosis","volume":"264","author":"Kul","year":"2017","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.carrev.2025.01.012_bb0170","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.carrev.2024.05.001","article-title":"Coronary microvascular dysfunction and cancer therapy-related cardiovascular toxicity","volume":"68","author":"Chitturi","year":"2024","journal-title":"Cardiovasc Revasc Med"},{"issue":"3","key":"10.1016\/j.carrev.2025.01.012_bb0175","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1093\/eurheartj\/ehz425","article-title":"2019 ESC Guidelines for the diagnosis and management of chronic coronary syndromes","volume":"41","author":"Knuuti","year":"2020","journal-title":"Eur Heart J"},{"issue":"6","key":"10.1016\/j.carrev.2025.01.012_bb0180","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1093\/eurheartj\/ehr331","article-title":"Stable angina pectoris with no obstructive coronary artery disease is associated with increased risks of major adverse cardiovascular events","volume":"33","author":"Jespersen","year":"2012","journal-title":"Eur Heart J"},{"key":"10.1016\/j.carrev.2025.01.012_bb0185","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.ijcard.2018.04.004","article-title":"Population-level incidence and outcomes of myocardial infarction with non-obstructive coronary arteries (MINOCA): insights from the Alberta contemporary acute coronary syndrome patients invasive treatment strategies (COAPT) study","volume":"264","author":"Bainey","year":"2018","journal-title":"Int J Cardiol"},{"issue":"1","key":"10.1016\/j.carrev.2025.01.012_bb0190","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1186\/s12872-018-0908-z","article-title":"Impact of clinical presentation and presence of coronary sclerosis on long-term outcome of patients with non-obstructive coronary artery disease","volume":"18","author":"Kissel","year":"2018","journal-title":"BMC Cardiovasc Disord"},{"issue":"12","key":"10.1016\/j.carrev.2025.01.012_bb0195","doi-asserted-by":"crossref","first-page":"1264","DOI":"10.1016\/j.jacc.2023.06.044","article-title":"Comprehensive management of ANOCA, part 2-program development, treatment, and research initiatives: JACC state-of-the-art review","volume":"82","author":"Smilowitz","year":"2023","journal-title":"J Am Coll Cardiol"},{"issue":"6","key":"10.1016\/j.carrev.2025.01.012_bb0200","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1016\/j.carrev.2017.04.012","article-title":"Impact of ranolazine on coronary microvascular dysfunction (MICRO) study","volume":"18","author":"Ahmed","year":"2017","journal-title":"Cardiovasc Revasc Med"}],"container-title":["Cardiovascular Revascularization Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1553838925000260?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1553838925000260?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,3,3]],"date-time":"2025-03-03T21:22:27Z","timestamp":1741036947000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1553838925000260"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2]]},"references-count":40,"alternative-id":["S1553838925000260"],"URL":"https:\/\/doi.org\/10.1016\/j.carrev.2025.01.012","relation":{},"ISSN":["1553-8389"],"issn-type":[{"value":"1553-8389","type":"print"}],"subject":[],"published":{"date-parts":[[2025,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Coronary microvascular dysfunction endotypes: IMR tips and tricks","name":"articletitle","label":"Article Title"},{"value":"Cardiovascular Revascularization Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.carrev.2025.01.012","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}