{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,25]],"date-time":"2026-04-25T09:26:07Z","timestamp":1777109167232,"version":"3.51.4"},"reference-count":38,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2010,6,1]],"date-time":"2010-06-01T00:00:00Z","timestamp":1275350400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Comparative Biochemistry and Physiology Part D: Genomics and Proteomics"],"published-print":{"date-parts":[[2010,6]]},"DOI":"10.1016\/j.cbd.2010.01.001","type":"journal-article","created":{"date-parts":[[2010,1,29]],"date-time":"2010-01-29T11:59:50Z","timestamp":1264766390000},"page":"81-88","source":"Crossref","is-referenced-by-count":19,"title":["Venomics of the spider Ornithoctonus huwena based on transcriptomic versus proteomic analysis"],"prefix":"10.1016","volume":"5","author":[{"given":"Liping","family":"Jiang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dongyi","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yongqun","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li","family":"Peng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jinjun","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Songping","family":"Liang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.cbd.2010.01.001_bib1","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1038\/75556","article-title":"Gene ontology: tool for the unification of biology. The Gene Ontology Consortium.","volume":"25","author":"Ashburner","year":"2000","journal-title":"Nat. Genet."},{"key":"10.1016\/j.cbd.2010.01.001_bib2","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1016\/j.jmb.2004.05.028","article-title":"Improved prediction of signal peptides: SignalP 3.0","volume":"340","author":"Bendtsen","year":"2004","journal-title":"J. Mol. Biol."},{"key":"10.1016\/j.cbd.2010.01.001_bib3","doi-asserted-by":"crossref","first-page":"D34","DOI":"10.1093\/nar\/gki063","article-title":"GenBank","volume":"33","author":"Benson","year":"2005","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.cbd.2010.01.001_bib4","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1038\/298686a0","article-title":"Mechanism of C-terminal amide formation by pituitary enzymes","volume":"298","author":"Bradbury","year":"1982","journal-title":"Nature"},{"key":"10.1016\/j.cbd.2010.01.001_bib5","doi-asserted-by":"crossref","first-page":"2431","DOI":"10.1007\/s00018-008-8135-x","article-title":"Molecular diversity and evolution of cystine knot toxins of the tarantula Chilobrachys jingzhao","volume":"65","author":"Chen","year":"2008","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.cbd.2010.01.001_bib6","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1016\/j.toxicon.2003.08.007","article-title":"cDNA sequence analysis of seven peptide toxins from the spider Selenocosmia huwena","volume":"42","author":"Diao","year":"2003","journal-title":"Toxicon"},{"key":"10.1016\/j.cbd.2010.01.001_bib7","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1186\/1471-2148-8-70","article-title":"Unusual accelerated rate of deletions and insertions in toxin genes in the venom glands of the pygmy copperhead (Austrelaps labialis) from Kangaroo island","volume":"8","author":"Doley","year":"2008","journal-title":"BMC Evol. Biol."},{"key":"10.1016\/j.cbd.2010.01.001_bib8","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1002\/rcm.595","article-title":"Matrix-assisted laser desorption\/ionization time-of-flight mass spectrometry and high-performance liquid chromatography study of quantitative and qualitative variation in tarantula spider venoms","volume":"16","author":"Escoubas","year":"2002","journal-title":"Rapid Commun. Mass Spectrom."},{"key":"10.1016\/j.cbd.2010.01.001_bib9","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1016\/S0300-9084(00)01166-4","article-title":"Structure and pharmacology of spider venom neurotoxins","volume":"82","author":"Escoubas","year":"2000","journal-title":"Biochimie"},{"key":"10.1016\/j.cbd.2010.01.001_bib10","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1002\/jms.1389","article-title":"Venomics: unravelling the complexity of animal venoms with mass spectrometry","volume":"43","author":"Escoubas","year":"2008","journal-title":"J. Mass Spectrom."},{"key":"10.1016\/j.cbd.2010.01.001_bib11","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1016\/j.toxicon.2006.01.018","article-title":"Venom landscapes: mining the complexity of spider venoms via a combined cDNA and mass spectrometric approach","volume":"47","author":"Escoubas","year":"2006","journal-title":"Toxicon"},{"key":"10.1016\/j.cbd.2010.01.001_bib12","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1186\/1471-2164-9-279","article-title":"Transcriptome analysis of Loxosceles laeta (Araneae, Sicariidae) spider venomous gland using expressed sequence tags","volume":"9","author":"Fernandes-Pedrosa Mde","year":"2008","journal-title":"BMC Genomics"},{"key":"10.1016\/j.cbd.2010.01.001_bib13","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.gene.2004.03.024","article-title":"Bitis gabonica (Gaboon viper) snake venom gland: toward a catalog for the full-length transcripts (cDNA) and proteins","volume":"337","author":"Francischetti","year":"2004","journal-title":"Gene"},{"key":"10.1016\/j.cbd.2010.01.001_bib14","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1016\/j.toxicon.2006.01.017","article-title":"Peptide profiling by matrix-assisted laser desorption\/ionisation time-of-flight mass spectrometry of the Lasiodora parahybana tarantula venom gland","volume":"47","author":"Guette","year":"2006","journal-title":"Toxicon"},{"key":"10.1016\/j.cbd.2010.01.001_bib15","doi-asserted-by":"crossref","first-page":"1479","DOI":"10.1016\/j.toxicon.2008.03.024","article-title":"Molecular diversification based on analysis of expressed sequence tags from the venom glands of the Chinese bird spider Ornithoctonus huwena","volume":"51","author":"Jiang","year":"2008","journal-title":"Toxicon"},{"key":"10.1016\/j.cbd.2010.01.001_bib16","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1016\/j.peptides.2008.12.012","article-title":"Expression, purification and characterization of a group of lectin-like peptides from the spider Ornithoctonus huwena","volume":"30","author":"Jiang","year":"2009","journal-title":"Peptides"},{"key":"10.1016\/j.cbd.2010.01.001_bib17","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/S1570-9639(03)00111-0","article-title":"Cloning and expression of calglandulin, a new EF-hand protein from the venom glands of Bothrops insularis snake in E. coli","volume":"1648","author":"Junqueira-de-Azevedo Ide","year":"2003","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.cbd.2010.01.001_bib18","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1016\/j.toxicon.2004.02.001","article-title":"The wonderful world of spiders: preface to the special Toxicon issue on spider venoms","volume":"43","author":"King","year":"2004","journal-title":"Toxicon"},{"key":"10.1016\/j.cbd.2010.01.001_bib19","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1002\/prot.20390","article-title":"A novel strategy for the identification of toxinlike structures in spider venom","volume":"59","author":"Kozlov","year":"2005","journal-title":"Proteins"},{"key":"10.1016\/j.cbd.2010.01.001_bib20","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1002\/1520-6327(200007)44:3<101::AID-ARCH1>3.0.CO;2-S","article-title":"A lysine rich C-terminal tail is directly involved in the toxicity of CSTX-1, a neurotoxic peptide from the venom of the spider Cupiennius salei","volume":"44","author":"Kuhn-Nentwig","year":"2000","journal-title":"Arch. Insect Biochem. Physiol."},{"key":"10.1016\/j.cbd.2010.01.001_bib21","doi-asserted-by":"crossref","first-page":"2947","DOI":"10.1093\/bioinformatics\/btm404","article-title":"Clustal W and Clustal X version 2.0","volume":"23","author":"Larkin","year":"2007","journal-title":"Bioinformatics"},{"key":"10.1016\/j.cbd.2010.01.001_bib22","doi-asserted-by":"crossref","first-page":"882","DOI":"10.1074\/mcp.M600334-MCP200","article-title":"Anti-infection peptidomics of amphibian skin","volume":"6","author":"Li","year":"2007","journal-title":"Mol. Cell. Proteomics"},{"key":"10.1016\/j.cbd.2010.01.001_bib23","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1016\/j.toxicon.2004.02.005","article-title":"An overview of peptide toxins from the venom of the Chinese bird spider Selenocosmia huwena Wang [=Ornithoctonus huwena (Wang)]","volume":"43","author":"Liang","year":"2004","journal-title":"Toxicon"},{"key":"10.1016\/j.cbd.2010.01.001_bib24","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1586\/14789450.5.5.731","article-title":"Proteome and peptidome profiling of spider venoms","volume":"5","author":"Liang","year":"2008","journal-title":"Expert Rev. Proteomics"},{"key":"10.1016\/j.cbd.2010.01.001_bib25","doi-asserted-by":"crossref","first-page":"1892","DOI":"10.1002\/pmic.200600785","article-title":"Proteomic and peptidomic analysis of the venom from Chinese tarantula Chilobrachys jingzhao","volume":"7","author":"Liao","year":"2007","journal-title":"Proteomics"},{"key":"10.1016\/j.cbd.2010.01.001_bib26","doi-asserted-by":"crossref","first-page":"W459","DOI":"10.1093\/nar\/gkl066","article-title":"EGassembler: online bioinformatics service for large-scale processing, clustering and assembling ESTs and genomic DNA fragments","volume":"34","author":"Masoudi-Nejad","year":"2006","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.cbd.2010.01.001_bib27","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/S0041-0101(03)00141-7","article-title":"cDNA sequence and in vitro folding of GsMTx4, a specific peptide inhibitor of mechanosensitive channels","volume":"42","author":"Ostrow","year":"2003","journal-title":"Toxicon"},{"key":"10.1016\/j.cbd.2010.01.001_bib28","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1002\/rcm.1751","volume":"19","author":"Pimenta","year":"2005","journal-title":"Rapid Commun. Mass Spectrom."},{"key":"10.1016\/j.cbd.2010.01.001_bib29","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.cbpc.2005.09.010","article-title":"Comparison of the partial proteomes of the venoms of Brazilian spiders of the genus Phoneutria","volume":"142","author":"Richardson","year":"2006","journal-title":"Comp. Biochem. Physiol. C Toxicol. Pharmacol."},{"key":"10.1016\/j.cbd.2010.01.001_bib30","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.jprot.2007.10.004","article-title":"Snake venomics of the South and Central American Bushmasters. Comparison of the toxin composition of Lachesis muta gathered from proteomic versus transcriptomic analysis.","volume":"71","author":"Sanz","year":"2008","journal-title":"J. Proteomics"},{"key":"10.1016\/j.cbd.2010.01.001_bib31","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1016\/j.cbpb.2006.07.009","article-title":"Molecular cloning of the heat-shock cognate 70 (Hsc70) gene from the two-spotted spider mite, Tetranychus urticae, and its expression in response to heat shock and starvation","volume":"145","author":"Shim","year":"2006","journal-title":"Comp. Biochem. Physiol. B Biochem. Mol. Biol."},{"key":"10.1016\/j.cbd.2010.01.001_bib32","doi-asserted-by":"crossref","first-page":"2679","DOI":"10.1007\/s00018-005-5384-9","article-title":"Identification and analysis of venom gland-specific genes from the coastal taipan (Oxyuranus scutellatus) and related species","volume":"62","author":"St Pierre","year":"2005","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.cbd.2010.01.001_bib33","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1186\/1471-2105-4-41","article-title":"The COG database: an updated version includes eukaryotes","volume":"4","author":"Tatusov","year":"2003","journal-title":"BMC Bioinformatics"},{"key":"10.1016\/j.cbd.2010.01.001_bib34","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1016\/j.toxicon.2004.02.010","article-title":"Australian funnel-web spiders: master insecticide chemists","volume":"43","author":"Tedford","year":"2004","journal-title":"Toxicon"},{"key":"10.1016\/j.cbd.2010.01.001_bib35","doi-asserted-by":"crossref","first-page":"2792","DOI":"10.1021\/pr0700192","article-title":"Proteomic and peptidomic characterization of the venom from the Chinese bird spider, Ornithoctonus huwena Wang","volume":"6","author":"Yuan","year":"2007","journal-title":"J. Proteome Res."},{"key":"10.1016\/j.cbd.2010.01.001_bib36","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1186\/1471-2164-7-152","article-title":"Transcriptome analysis of Deinagkistrodon acutus venomous gland focusing on cellular structure and functional aspects using expressed sequence tags","volume":"7","author":"Zhang","year":"2006","journal-title":"BMC Genomics"},{"key":"10.1016\/j.cbd.2010.01.001_bib37","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/S0041-0101(03)00095-3","article-title":"Huwentoxin-V, a novel insecticidal peptide toxin from the spider Selenocosmia huwena, and a natural mutant of the toxin: indicates the key amino acid residues related to the biological activity","volume":"42","author":"Zhang","year":"2003","journal-title":"Toxicon"},{"key":"10.1016\/j.cbd.2010.01.001_bib38","series-title":"Zoology","article-title":"Transcriptome analysis of the venom glands of the Chinese wolf spider Lycosa singoriensis","author":"Zhang","year":"2009"}],"container-title":["Comparative Biochemistry and Physiology Part D: Genomics and Proteomics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1744117X1000002X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1744117X1000002X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,12,13]],"date-time":"2018-12-13T15:57:35Z","timestamp":1544716655000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1744117X1000002X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,6]]},"references-count":38,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2010,6]]}},"alternative-id":["S1744117X1000002X"],"URL":"https:\/\/doi.org\/10.1016\/j.cbd.2010.01.001","relation":{},"ISSN":["1744-117X"],"issn-type":[{"value":"1744-117X","type":"print"}],"subject":[],"published":{"date-parts":[[2010,6]]}}}