{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T17:54:31Z","timestamp":1781027671326,"version":"3.54.1"},"reference-count":63,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2023YFD2401003"],"award-info":[{"award-number":["2023YFD2401003"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007710","name":"Jilin Agricultural University","doi-asserted-by":"publisher","award":["20230202076NC"],"award-info":[{"award-number":["20230202076NC"]}],"id":[{"id":"10.13039\/501100007710","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007710","name":"Jilin Agricultural University","doi-asserted-by":"publisher","award":["202301401"],"award-info":[{"award-number":["202301401"]}],"id":[{"id":"10.13039\/501100007710","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Comparative Biochemistry and Physiology Part D: Genomics and Proteomics"],"published-print":{"date-parts":[[2025,9]]},"DOI":"10.1016\/j.cbd.2025.101457","type":"journal-article","created":{"date-parts":[[2025,2,26]],"date-time":"2025-02-26T19:22:26Z","timestamp":1740597746000},"page":"101457","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Silymarin mediates the gut-liver axis pathway to alleviate Carassius auratus hepatic lipid metabolism disorders caused by carbonate exposure"],"prefix":"10.1016","volume":"55","author":[{"given":"Xin-yu","family":"Lei","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xue","family":"Cao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yue-hong","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.cbd.2025.101457_bb0005","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1152\/physrev.00003.2008","article-title":"Zonulin and its regulation of intestinal barrier function: the biological door to inflammation, autoimmunity, and cancer","volume":"91","author":"Alessio","year":"2011","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.cbd.2025.101457_bb0010","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1016\/j.freeradbiomed.2019.01.016","article-title":"Redox regulation by NRF2 in aging and disease","volume":"134","author":"C","year":"2019","journal-title":"Free Radic. Biol. Med."},{"issue":"C","key":"10.1016\/j.cbd.2025.101457_bb0015","article-title":"Compound probiotics alleviating aflatoxin B 1 and zearalenone toxic effects on broiler production performance and gut microbiota","volume":"194","author":"Chang","year":"2020","journal-title":"Ecotoxicol. Environ. Saf."},{"issue":"7","key":"10.1016\/j.cbd.2025.101457_bb0020","doi-asserted-by":"crossref","first-page":"1657","DOI":"10.1053\/j.gastro.2004.03.013","article-title":"Molecular defects in mucosal serotonin content and decreased serotonin reuptake transporter in ulcerative colitis and irritable bowel syndrome","volume":"126","author":"D","year":"2004","journal-title":"Gastroenterology"},{"issue":"5","key":"10.1016\/j.cbd.2025.101457_bb0025","doi-asserted-by":"crossref","first-page":"948","DOI":"10.1194\/jlr.M300520-JLR200","article-title":"A prospective study of HDL-C and cholesteryl ester transfer protein gene mutations and the risk of coronary heart disease in the elderly","volume":"45","author":"D","year":"2004","journal-title":"J. Lipid Res."},{"issue":"1","key":"10.1016\/j.cbd.2025.101457_bb0030","first-page":"266","article-title":"Melatonin pretreatment protects against status epilepticus, glutamate transport, and oxidative stress induced by kainic acid in zebrafish","volume":"59","author":"D","year":"2021","journal-title":"Mol. Neurobiol."},{"issue":"1","key":"10.1016\/j.cbd.2025.101457_bb0035","first-page":"75","article-title":"D-lactic acidosis - case report and review of the literature","volume":"55","author":"Elisabeth","year":"2017","journal-title":"Zeitschrift fur Gastroenterologie."},{"issue":"15","key":"10.1016\/j.cbd.2025.101457_bb0040","doi-asserted-by":"crossref","first-page":"4620","DOI":"10.1128\/AEM.00821-13","article-title":"The genome of the anaerobic fungus Orpinomyces sp. strain C1A reveals the unique evolutionary history of a remarkable plant biomass degrader","volume":"79","author":"H","year":"2013","journal-title":"Appl. Environ. Microbiol."},{"key":"10.1016\/j.cbd.2025.101457_bb0045","first-page":"243","article-title":"Analysis of the current situation of water resources in China and countermeasures for sustainable development","volume":"09","author":"Haishu","year":"2017","journal-title":"Heilongjiang Sci. Technol. Inf."},{"issue":"1","key":"10.1016\/j.cbd.2025.101457_bb0050","article-title":"The gut microbiome and degradation enzyme activity of wild freshwater fishes influenced by their trophic levels","volume":"6","author":"Han","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.cbd.2025.101457_bb0055","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.procbio.2023.11.005","article-title":"Non-targeted metabolomics reveals a modulatory effect of DHA-enriched phosphatidylserine in high fat-diet induced non-alcoholic fatty liver disease in mice","volume":"135","author":"Honglei","year":"2023","journal-title":"Process Biochem."},{"issue":"5","key":"10.1016\/j.cbd.2025.101457_bb0060","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1007\/s10545-010-9061-2","article-title":"A general introduction to the biochemistry of mitochondrial fatty acid \u03b2-oxidation","volume":"33","author":"Houten","year":"2010","journal-title":"J. Inherit. Metab. Dis."},{"issue":"1","key":"10.1016\/j.cbd.2025.101457_bb0065","first-page":"1","article-title":"Role of Nrf2 in cell senescence regulation","volume":"476","author":"Huan","year":"2020","journal-title":"Mol. Cell. Biochem."},{"issue":"24","key":"10.1016\/j.cbd.2025.101457_bb0070","doi-asserted-by":"crossref","first-page":"4765","DOI":"10.1128\/JB.180.18.4765-4774.1998","article-title":"Impact of culture-independent studies on the emerging phylogenetic view of bacterial diversity","volume":"180","author":"Hugenholtz","year":"1998","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.cbd.2025.101457_bb0075","series-title":"Molecular Mechanism of Intestinal Injury Induced by NaHCO3 Stress and Regulation of Biostime in Crucian Carp","author":"Jia","year":"2023"},{"key":"10.1016\/j.cbd.2025.101457_bb0080","series-title":"Tolerance and Immune Stress Response of 5 Fish Species under Salt and Alkali Stress","author":"Jian","year":"2014"},{"issue":"36","key":"10.1016\/j.cbd.2025.101457_bb0085","doi-asserted-by":"crossref","first-page":"85223","DOI":"10.1007\/s11356-023-28083-x","article-title":"Effects of high NaHCO3 alkalinity on growth, tissue structure, digestive enzyme activity, and gut microflora of grass carp juvenile","volume":"30","author":"Jian","year":"2023","journal-title":"Environ. Sci. Pollut. Res. Int."},{"key":"10.1016\/j.cbd.2025.101457_bb0090","article-title":"Essential oil from Artemisia argyi alleviated liver disease in zebrafish (Danio rerio) via the gut-liver axis","volume":"140","author":"Jianjie","year":"2023","journal-title":"Fish Shellfish Immunol."},{"issue":"08","key":"10.1016\/j.cbd.2025.101457_bb0095","first-page":"1224","article-title":"Effects of silymarin on liver injury and bone metabolism induced by carbon tetrachloride in mice","volume":"25","author":"Jiming","year":"2021","journal-title":"Tissue Eng. Res. China."},{"issue":"03","key":"10.1016\/j.cbd.2025.101457_bb0100","first-page":"18","article-title":"Ecological engineering technology and comprehensive development suggestion of converting fishery to alkali in Yellow River delta","author":"Jinlu","year":"2009","journal-title":"Fish. Hebei"},{"issue":"07","key":"10.1016\/j.cbd.2025.101457_bb0105","first-page":"971","article-title":"Silymarin improves nonalcoholic fatty liver disease by regulating Nrf2 antioxidant pathway and inhibiting NLRP3 inflammatome","volume":"36","author":"Jun","year":"2020","journal-title":"Chin. Pharmacol. Bull."},{"issue":"1","key":"10.1016\/j.cbd.2025.101457_bb0110","doi-asserted-by":"crossref","first-page":"4281","DOI":"10.1038\/s41598-020-61256-z","article-title":"The effect of synbiotic preparations on the intestinal microbiota and her metabolism in broiler chickens","volume":"10","author":"Katarzyna","year":"2020","journal-title":"Sci. Rep."},{"issue":"04","key":"10.1016\/j.cbd.2025.101457_bb0115","first-page":"145","article-title":"Accumulation of antimony in different tissues of zebrafish and its effects on anti-oxidation system","volume":"37","author":"Kun","year":"2021","journal-title":"Biotechnol. Bull."},{"key":"10.1016\/j.cbd.2025.101457_bb0120","doi-asserted-by":"crossref","DOI":"10.1016\/j.aquatox.2023.106688","article-title":"Flunitrazepam and its metabolites exposure disturb the zebrafish gut-liver axis: combined microbiome and metabolomic analysis","volume":"263","author":"Lin","year":"2023","journal-title":"Aquat. Toxicol."},{"issue":"04","key":"10.1016\/j.cbd.2025.101457_bb0125","first-page":"138","article-title":"Comprehensive development and utilization of inland salty (saline-alkali) water resources and fishery in China","volume":"31","author":"Liqun","year":"2013","journal-title":"Chin. Fish. Econ."},{"issue":"01","key":"10.1016\/j.cbd.2025.101457_bb0130","first-page":"141","article-title":"Effects of starvation stress on growth, body composition, digestive enzyme activity and antioxidant activity of juvenile Carassius auratus Pengze","volume":"48","author":"Liyun","year":"2019","journal-title":"Henan Agric. Sci."},{"issue":"01","key":"10.1016\/j.cbd.2025.101457_bb0135","first-page":"19","article-title":"Effects of different alkalinity and Alpha ketoglutaric acid levels on intestinal morphology and digestive enzyme activities of Mirror Cyprinus songpu","volume":"33","author":"Long","year":"2020","journal-title":"J. Aquat. Sci."},{"issue":"03","key":"10.1016\/j.cbd.2025.101457_bb0140","first-page":"1293","article-title":"Effects of dietary methionine level on growth performance, muscle quality and gene expression related to muscle synthesis pathway of Mirror Cyprinus Songpu","volume":"32","author":"Long","year":"2020","journal-title":"Chin. J. Anim. Nutr."},{"key":"10.1016\/j.cbd.2025.101457_bb0145","doi-asserted-by":"crossref","first-page":"2295","DOI":"10.1007\/s10499-022-00902-x","article-title":"Effects of dietary supplementation with Bacillus subtilis on immune, antioxidant, and histopathological parameters of Carassius auratus gibelio juveniles exposed to acute saline-alkaline conditions","volume":"5","author":"Lu","year":"2022","journal-title":"Aquac. Int."},{"key":"10.1016\/j.cbd.2025.101457_bb0150","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.ceb.2016.05.006","article-title":"Tight junctions as regulators of tissue remodelling","volume":"42","author":"M","year":"2016","journal-title":"Curr. Opin. Cell Biol."},{"issue":"6","key":"10.1016\/j.cbd.2025.101457_bb0155","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1111\/j.1365-2982.2012.01921.x","article-title":"Intestinal barrier function in health and gastrointestinal disease","volume":"24","author":"M","year":"2012","journal-title":"Neurogastroenterol. Motil."},{"key":"10.1016\/j.cbd.2025.101457_bb0160","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.bbi.2013.12.005","article-title":"Altered gut microbiota and activity in a murine model of autism spectrum disorders","volume":"37","author":"M","year":"2014","journal-title":"Brain Behav. Immun."},{"issue":"1","key":"10.1016\/j.cbd.2025.101457_bb0165","doi-asserted-by":"crossref","first-page":"122","DOI":"10.5115\/acb.22.204","article-title":"Silymarin attenuates escitalopram (cipralex) induced pancreatic injury in adult male albino rats: a biochemical, histological, and immunohistochemical approach","volume":"56","author":"Mamdouh","year":"2023","journal-title":"Anatomy Cell Biol."},{"issue":"1","key":"10.1016\/j.cbd.2025.101457_bb0170","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1128\/MCB.25.1.162-171.2005","article-title":"BTB protein Keap1 targets antioxidant transcription factor Nrf2 for ubiquitination by the Cullin 3-Roc1 ligase","volume":"25","author":"Manabu","year":"2005","journal-title":"Mol. Cell. Biol."},{"issue":"1","key":"10.1016\/j.cbd.2025.101457_bb0175","doi-asserted-by":"crossref","first-page":"3964","DOI":"10.1038\/s41467-022-31312-5","article-title":"Imbalanced gut microbiota fuels hepatocellular carcinoma development by shaping the hepatic inflammatory microenvironment","volume":"13","author":"Markus","year":"2022","journal-title":"Nat. Commun."},{"issue":"1","key":"10.1016\/j.cbd.2025.101457_bb0180","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1159\/000282091","article-title":"Bile acids as regulators of hepatic lipid and glucose metabolism","volume":"28","author":"Michael","year":"2010","journal-title":"Dig. Dis. (Basel, Switzerland)"},{"key":"10.1016\/j.cbd.2025.101457_bb0185","article-title":"The molecular mechanisms of alpha-lipoic acid on ameliorating aflatoxin B1-induced liver toxicity and physiological dysfunction in northern snakehead (Channa argus)","volume":"257","author":"Min","year":"2023","journal-title":"Aquat. Toxicol."},{"issue":"1","key":"10.1016\/j.cbd.2025.101457_bb0190","first-page":"203","article-title":"Growth performance and osmoregulation in the shi drum (Umbrina cirrosa) adapted to different environmental salinities","volume":"287","author":"Mylonas","year":"2008","journal-title":"Aquaculture"},{"key":"10.1016\/j.cbd.2025.101457_bb0195","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.aninu.2023.07.005","article-title":"An emerging role of arecoline on growth performance, intestinal digestion and absorption capacities and intestinal structural integrity of adult grass carp (Ctenopharyngodon idella)","volume":"15","author":"Na","year":"2023","journal-title":"Anim. Nutr."},{"issue":"01","key":"10.1016\/j.cbd.2025.101457_bb0200","first-page":"98","article-title":"Effects of carbonate alkalinity on growth and serum biochemical indices of 3-month-old hybrid Acipenser (Huso dauricus \u00d7Acipenser schrenckii)","volume":"32","author":"Nianmin","year":"2023","journal-title":"J. Shanghai Ocean Univ."},{"issue":"12","key":"10.1016\/j.cbd.2025.101457_bb0205","first-page":"1205","article-title":"Glucocorticoid sparing of benralizumab in asthma","volume":"377","author":"Parameswaran","year":"2017","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.cbd.2025.101457_bb0210","article-title":"An integrated analysis of transcriptome and metabolome reveals three BCAAs relieve lipid accumulation by inhibiting lipid synthesis and promoting lipid oxidation in the liver of largemouth bass (Micropterus salmoides)","volume":"581","author":"Qiang","year":"2024","journal-title":"Aquaculture"},{"key":"10.1016\/j.cbd.2025.101457_bb0215","first-page":"219","article-title":"Study on salt-alkali tolerance of embryo and larva of Aral Sea Carabinus","volume":"02","author":"Qiuli","year":"2008","journal-title":"J. Jilin Agric. Univ."},{"issue":"7","key":"10.1016\/j.cbd.2025.101457_bb0220","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1038\/nrd1776","article-title":"The emerging field of lipidomics","volume":"4","author":"R","year":"2005","journal-title":"Nat. Rev. Drug Discov."},{"issue":"2","key":"10.1016\/j.cbd.2025.101457_bb0225","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1002\/pro.3797","article-title":"Type I fatty acid synthase trapped in the octanoyl-bound state","volume":"29","author":"Rittner","year":"2020","journal-title":"Protein Sci."},{"issue":"11","key":"10.1016\/j.cbd.2025.101457_bb0230","doi-asserted-by":"crossref","first-page":"1860","DOI":"10.1038\/s41388-018-0545-0","article-title":"Forcing ATGL expression in hepatocarcinoma cells imposes glycolytic rewiring through PPAR-\u03b1\/p300-mediated acetylation of p53","volume":"38","author":"Rolando","year":"2019","journal-title":"Oncogene"},{"issue":"03","key":"10.1016\/j.cbd.2025.101457_bb0235","first-page":"551","article-title":"Protective and antioxidant effects of silymarin on liver (cell) damage induced by carbon tetrachloride in Carassius auratus","volume":"20","author":"Rui","year":"2013","journal-title":"Chin. Fish. Sci."},{"issue":"6785","key":"10.1016\/j.cbd.2025.101457_bb0240","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1038\/35013000","article-title":"Roles of PPARs in health and disease","volume":"405","author":"S","year":"2000","journal-title":"Nature"},{"issue":"3","key":"10.1016\/j.cbd.2025.101457_bb0245","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/j.freeradbiomed.2008.04.029","article-title":"Fatty acids as modulators of the cellular production of reactive oxygen species","volume":"45","author":"Sch\u00f6nfeld","year":"2008","journal-title":"Free Radic. Biol. Med."},{"issue":"03","key":"10.1016\/j.cbd.2025.101457_bb0250","first-page":"24","article-title":"Effects of different NaHCO3 alkalinity on the microstructure of kidney and intestinal tissues of Yarro Walteri","volume":"33","author":"Shan","year":"2020","journal-title":"J. Aquat. Sci."},{"issue":"1","key":"10.1016\/j.cbd.2025.101457_bb0255","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.cca.2009.01.028","article-title":"Role of serotonin in gastrointestinal motility and irritable bowel syndrome","volume":"403","author":"Sikander","year":"2009","journal-title":"Clin. Chim. Acta"},{"key":"10.1016\/j.cbd.2025.101457_bb0260","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1146\/annurev.nutr.22.020402.130846","article-title":"Fatty acid transport across membranes: relevance to nutrition and metabolic pathology","volume":"22","author":"Tahar","year":"2002","journal-title":"Annu. Rev. Nutr."},{"issue":"1","key":"10.1016\/j.cbd.2025.101457_bb0265","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1007\/s00248-014-0480-8","article-title":"Comparative analysis of the intestinal bacterial communities in different species of carp by pyrosequencing","volume":"69","author":"Tongtong","year":"2015","journal-title":"Microb. Ecol."},{"issue":"1","key":"10.1016\/j.cbd.2025.101457_bb0270","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1042\/bj3370133","article-title":"Secretion and apparent activation of human hepatic lipase requires proper oligosaccharide processing in the endoplasmic reticulum","volume":"337 (Pt 1)","author":"Verhoeven","year":"1999","journal-title":"Biochem. J."},{"key":"10.1016\/j.cbd.2025.101457_bb0275","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.aquaculture.2020.735311","article-title":"Dietary silymarin supplementation enhanced growth performance and improved intestinal apical junctional complex on juvenile grass carp (Ctenopharyngodon idella)","volume":"525","author":"Wei","year":"2020","journal-title":"Aquaculture"},{"issue":"07","key":"10.1016\/j.cbd.2025.101457_bb0280","first-page":"128","article-title":"The role of enterohepatic axis in animal nutrition metabolism and immunity","volume":"38","author":"Xianzhe","year":"2022","journal-title":"Biotechnol. Bull."},{"key":"10.1016\/j.cbd.2025.101457_bb0285","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.livsci.2016.06.008","article-title":"Effects of chito-oligosaccharide on intestinal mucosal amino acid profiles and alkaline phosphatase activities, and serum biochemical variables in weaned piglets","volume":"190","author":"Yang","year":"2016","journal-title":"Livest. Sci."},{"issue":"04","key":"10.1016\/j.cbd.2025.101457_bb0290","first-page":"392","article-title":"Metformin inhibits colorectal cancer metastasis by regulating ppar\u03b3-mediated fatty acid metabolism","volume":"45","author":"Yuanping","year":"2023","journal-title":"J. Inner Mong. Med. Univ."},{"issue":"03","key":"10.1016\/j.cbd.2025.101457_bb0295","first-page":"577","article-title":"Effects of NaCl salinity and NaHCO3 alkalinity on growth and gill tissue characteristics of juvenile Barbus macrolepidus","volume":"20","author":"Yunfei","year":"2013","journal-title":"Chin. Fish. Sci."},{"issue":"11","key":"10.1016\/j.cbd.2025.101457_bb0300","first-page":"32","article-title":"Effect of NaHCO3 alkalinity stress on oxidative stress level of Sinocyclocheilus macrolepidus","volume":"51","author":"Yuting","year":"2021","journal-title":"J. Ocean Univ. China (Nat. Sci.)"},{"key":"10.1016\/j.cbd.2025.101457_bb0305","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1016\/j.trac.2019.05.030","article-title":"Mass spectrometry-based non-targeted metabolic profiling for disease detection: recent developments","volume":"118","author":"Zang","year":"2019","journal-title":"Trends Anal. Chem."},{"key":"10.1016\/j.cbd.2025.101457_bb0310","article-title":"Carbonate alkalinity and dietary protein levels affected growth performance, intestinal immune responses and intestinal microflora in Songpu mirror carp (Cyprinus carpio Songpu)","volume":"545","author":"Ze","year":"2021","journal-title":"Aquaculture"},{"key":"10.1016\/j.cbd.2025.101457_bb0315","series-title":"Study on the Mechanism of Melatonin Alleviating Fatty Liver Induced by Lead Exposure in Carp Via Enterohepatic Axis","author":"Zhiying","year":"2021"}],"container-title":["Comparative Biochemistry and Physiology Part D: Genomics and Proteomics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1744117X25000450?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1744117X25000450?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T23:15:04Z","timestamp":1762557304000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1744117X25000450"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9]]},"references-count":63,"alternative-id":["S1744117X25000450"],"URL":"https:\/\/doi.org\/10.1016\/j.cbd.2025.101457","relation":{},"ISSN":["1744-117X"],"issn-type":[{"value":"1744-117X","type":"print"}],"subject":[],"published":{"date-parts":[[2025,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Silymarin mediates the gut-liver axis pathway to alleviate Carassius auratus hepatic lipid metabolism disorders caused by carbonate exposure","name":"articletitle","label":"Article Title"},{"value":"Comparative Biochemistry and Physiology Part D: Genomics and Proteomics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cbd.2025.101457","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"101457"}}