{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,27]],"date-time":"2026-01-27T07:56:11Z","timestamp":1769500571064,"version":"3.49.0"},"reference-count":62,"publisher":"Elsevier BV","issue":"2-3","license":[{"start":{"date-parts":[[2009,12,1]],"date-time":"2009-12-01T00:00:00Z","timestamp":1259625600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2009,12,1]],"date-time":"2009-12-01T00:00:00Z","timestamp":1259625600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100013414","name":"Conseil R\u00e9gional des Pays de la Loire","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100013414","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001677","name":"Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001677","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Chemico-Biological Interactions"],"published-print":{"date-parts":[[2009,12]]},"DOI":"10.1016\/j.cbi.2009.09.010","type":"journal-article","created":{"date-parts":[[2009,9,24]],"date-time":"2009-09-24T06:24:00Z","timestamp":1253773440000},"page":"98-105","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":25,"title":["Effect of alpha tocopherol acetate in Walker 256\/B cells-induced oxidative damage in a rat model of breast cancer skeletal metastases"],"prefix":"10.1016","volume":"182","author":[{"given":"Riadh","family":"Badraoui","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"St\u00e9phane","family":"Blouin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marie Fran\u00e7oise","family":"Moreau","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yves","family":"Gallois","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tarek","family":"Rebai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zouhaier","family":"Sahnoun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michel","family":"Basl\u00e9","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Chappard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"8","key":"10.1016\/j.cbi.2009.09.010_bib1","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1038\/nrc867","article-title":"Metastasis to bone: causes, consequences and therapeutic opportunities","volume":"2","author":"Mundy","year":"2002","journal-title":"Nat. Rev. Cancer"},{"issue":"3","key":"10.1016\/j.cbi.2009.09.010_bib2","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1053\/ctrv.2000.0210","article-title":"Metastatic bone disease: clinical features, pathophysiology and treatment strategies","volume":"27","author":"Coleman","year":"2001","journal-title":"Cancer Treat. Rev."},{"issue":"8","key":"10.1016\/j.cbi.2009.09.010_bib3","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1007\/s10585-006-9002-5","article-title":"Rat models of bone metastases","volume":"22","author":"Blouin","year":"2005","journal-title":"Clin. Exp. Metastasis"},{"issue":"3\u20134","key":"10.1016\/j.cbi.2009.09.010_bib4","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1159\/000093967","article-title":"Relations between radiograph texture analysis and microcomputed tomography in two rat models of bone metastases","volume":"182","author":"Blouin","year":"2006","journal-title":"Cells Tissues Organs"},{"issue":"4","key":"10.1016\/j.cbi.2009.09.010_bib5","doi-asserted-by":"crossref","first-page":"1292","DOI":"10.1016\/j.bbrc.2006.04.186","article-title":"A rat model of bone cancer pain induced by intra-tibia inoculation of Walker 256 mammary gland carcinoma cells","volume":"345","author":"Mao-Ying","year":"2006","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"19","key":"10.1016\/j.cbi.2009.09.010_bib6","doi-asserted-by":"crossref","first-page":"9374","DOI":"10.1158\/0008-5472.CAN-06-2403","article-title":"Dietary administration of the proapoptotic vitamin E analogue {alpha}-tocopheryloxyacetic acid inhibits metastatic murine breast cancer","volume":"66","author":"Hahn","year":"2006","journal-title":"Cancer Res."},{"issue":"1\u20132","key":"10.1016\/j.cbi.2009.09.010_bib7","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0009-8981(01)00393-X","article-title":"Methods for monitoring oxidative stress, lipid peroxidation and oxidation resistance of lipoproteins","volume":"306","author":"Abuja","year":"2001","journal-title":"Clin. Chim. Acta"},{"issue":"1","key":"10.1016\/j.cbi.2009.09.010_bib8","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1016\/j.bbrc.2005.08.072","article-title":"Lipid peroxidation: mechanisms, inhibition, and biological effects","volume":"338","author":"Niki","year":"2005","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"1","key":"10.1016\/j.cbi.2009.09.010_bib9","first-page":"1","article-title":"Inflammation and oxidative stress in carcinogenesis","volume":"3","author":"Cerutti","year":"1991","journal-title":"Cancer Cells"},{"key":"10.1016\/j.cbi.2009.09.010_bib10","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/j.pestbp.2006.10.007","article-title":"May antioxidant status depletion by tetradifon induce secondary genotoxicity in female wistar rat via oxidative stress?","volume":"88","author":"Badraoui","year":"2007","journal-title":"Pesticide Biochem. Physiol."},{"issue":"1","key":"10.1016\/j.cbi.2009.09.010_bib11","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1080\/01411590310001637066","article-title":"Antioxidant enzymes and lipid peroxidation in different stages of breast cancer","volume":"38","author":"Khanzode","year":"2004","journal-title":"Free Radic. Res."},{"issue":"4","key":"10.1016\/j.cbi.2009.09.010_bib12","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1016\/j.cellbi.2006.02.005","article-title":"Lipid peroxidation and antioxidant status in blood and tissue of malignant breast tumor and benign breast disease","volume":"30","author":"Gonenc","year":"2006","journal-title":"Cell Biol. Int."},{"issue":"2","key":"10.1016\/j.cbi.2009.09.010_bib13","doi-asserted-by":"crossref","first-page":"347","DOI":"10.2174\/138945007779940151","article-title":"Antioxidant to treat osteoarthritis: dream or reality?","volume":"8","author":"Henrotin","year":"2007","journal-title":"Curr. Drug Targets"},{"key":"10.1016\/j.cbi.2009.09.010_bib14","doi-asserted-by":"crossref","first-page":"1404","DOI":"10.1152\/ajprenal.00260.2006","article-title":"E reduces glomerulosclerosis, restores renal neuronal NOS, and suppresses oxidative stress in the 5\/6 nephrectomized rat","volume":"292","author":"Tain","year":"2007","journal-title":"Am. J. Physiol. Renal Physiol."},{"issue":"2\u20133","key":"10.1016\/j.cbi.2009.09.010_bib15","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1016\/j.tox.2005.08.017","article-title":"Protective effects of vitamin E on endocrine disruptors, PCB-induced dopaminergic neurotoxicity","volume":"216","author":"Yun","year":"2005","journal-title":"Toxicology"},{"issue":"9","key":"10.1016\/j.cbi.2009.09.010_bib16","doi-asserted-by":"crossref","first-page":"1483","DOI":"10.1016\/j.freeradbiomed.2005.10.066","article-title":"Antioxidant alpha-lipoic acid inhibits osteoclast differentiation by reducing nuclear factor-kappaB DNA binding and prevents in vivo bone resorption induced by receptor activator of nuclear factor-kappaB ligand and tumor necrosis factor-alpha","volume":"40","author":"Kim","year":"2006","journal-title":"Free Radic. Biol. Med."},{"issue":"2","key":"10.1016\/j.cbi.2009.09.010_bib17","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1080\/07315724.2003.10719284","article-title":"The use of antioxidants with first-line chemotherapy in two cases of ovarian cancer","volume":"22","author":"Drisko","year":"2003","journal-title":"J. Am. Coll. Nutr."},{"issue":"3","key":"10.1016\/j.cbi.2009.09.010_bib18","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1016\/S0090-8258(02)00067-7","article-title":"The use of antioxidant therapies during chemotherapy","volume":"88","author":"Drisko","year":"2003","journal-title":"Gynecol. Oncol."},{"key":"10.1016\/j.cbi.2009.09.010_bib19","series-title":"Mathematical morphology and its applications to image processing","author":"Serra","year":"1994"},{"issue":"4","key":"10.1016\/j.cbi.2009.09.010_bib20","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/8756-3282(92)90078-B","article-title":"Trabecular bone pattern factor\u2014a new parameter for simple quantification of bone microarchitecture","volume":"13","author":"Hahn","year":"1992","journal-title":"Bone"},{"key":"10.1016\/j.cbi.2009.09.010_bib21","series-title":"Bone cancer: progression and therapeutic approaches","first-page":"203","article-title":"Technical aspects: How do we best prepare bone samples for proper histological analysis?","author":"Chappard","year":"2009"},{"issue":"1","key":"10.1016\/j.cbi.2009.09.010_bib22","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/0006-291X(87)91297-6","article-title":"Decreased lipid peroxidation in the rat kidney during gestation","volume":"145","author":"Devasagayam","year":"1987","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"5","key":"10.1016\/j.cbi.2009.09.010_bib23","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1042\/bj1230805","article-title":"The stimulatory effects of carbon tetrachloride and other halogenoalkanes on peroxidative reactions in rat liver fractions in vitro. General features of the systems used","volume":"123","author":"Slater","year":"1971","journal-title":"Biochem. J."},{"issue":"7","key":"10.1016\/j.cbi.2009.09.010_bib24","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1016\/S1357-2725(99)00034-5","article-title":"Quantitation of oxidative damage to tissue proteins","volume":"31","author":"Fagan","year":"1999","journal-title":"Int. J. Biochem. Cell Biol."},{"issue":"1","key":"10.1016\/j.cbi.2009.09.010_bib25","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/S0021-9258(19)50881-X","article-title":"A spectrophotometric method for measuring the breakdown of hydrogen peroxide by catalase","volume":"195","author":"Beers","year":"1952","journal-title":"J. Biol. Chem."},{"issue":"1","key":"10.1016\/j.cbi.2009.09.010_bib26","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1182\/blood.V46.1.103.103","article-title":"Ethnic variation in red cell glutathione peroxidase activity","volume":"46","author":"Beutler","year":"1975","journal-title":"Blood"},{"issue":"22","key":"10.1016\/j.cbi.2009.09.010_bib27","doi-asserted-by":"crossref","first-page":"6056","DOI":"10.1016\/S0021-9258(18)63505-7","article-title":"The utility of superoxide dismutase in studying free radical reactions. I. Radicals generated by the interaction of sulfite, dimethyl sulfoxide, and oxygen","volume":"244","author":"McCord","year":"1969","journal-title":"J. Biol. Chem."},{"issue":"4","key":"10.1016\/j.cbi.2009.09.010_bib28","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1002\/1097-0045(20000901)44:4<287::AID-PROS5>3.0.CO;2-Z","article-title":"Vitamin E and other antioxidants inhibit human prostate cancer cells through apoptosis","volume":"44","author":"Gunawardena","year":"2000","journal-title":"Prostate"},{"issue":"2","key":"10.1016\/j.cbi.2009.09.010_bib29","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1006\/abbi.1993.1222","article-title":"Evaluation of 2\u2032,7\u2032-dichlorofluorescin and dihydrorhodamine 123 as fluorescent probes for intracellular H2O2 in cultured endothelial cells","volume":"302","author":"Royall","year":"1993","journal-title":"Arch. Biochem. Biophys."},{"issue":"5\u20136","key":"10.1016\/j.cbi.2009.09.010_bib30","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1016\/S0891-5849(99)00107-0","article-title":"Quantifying cellular oxidative stress by dichlorofluorescein assay using microplate reader","volume":"27","author":"Wang","year":"1999","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.cbi.2009.09.010_bib31","first-page":"18","article-title":"Cancer and bone","volume":"19","author":"Guise","year":"1998","journal-title":"Endocr. Rev."},{"issue":"2","key":"10.1016\/j.cbi.2009.09.010_bib32","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1002\/jps.10032","article-title":"Pharmacokinetic and pharmacodynamic evaluation of intermittent versus continuous alendronate administration in rats","volume":"91","author":"Stepensky","year":"2002","journal-title":"J. Pharm. Sci."},{"issue":"4","key":"10.1016\/j.cbi.2009.09.010_bib33","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1007\/BF02555239","article-title":"The Walker 256\/B carcinosarcoma in thyroparathyroidectomized rats: a model to evaluate inhibitors of bone resorption","volume":"41","author":"Rizzoli","year":"1987","journal-title":"Calcif. Tissue Int."},{"issue":"1","key":"10.1016\/j.cbi.2009.09.010_bib34","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1002\/1097-0142(19930701)72:1<91::AID-CNCR2820720118>3.0.CO;2-2","article-title":"Prophylactic treatment of skeletal metastases, tumor-induced osteolysis, and hypercalcemia in rats with the bisphosphonate Cl2MBP","volume":"72","author":"Krempien","year":"1993","journal-title":"Cancer"},{"issue":"11","key":"10.1016\/j.cbi.2009.09.010_bib35","first-page":"1067","article-title":"Induction of cytokines in ascitic fluid by intraperitoneal OK-432 administration in patients with gastric cancer","volume":"31","author":"Takagane","year":"1996","journal-title":"J. Jpn. Soc. Cancer Ther."},{"issue":"2","key":"10.1016\/j.cbi.2009.09.010_bib36","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1046\/j.1365-2710.2001.00334.x","article-title":"Plasma malondialdehyde (MDA) levels in breast and lung cancer patients","volume":"26","author":"Gonenc","year":"2001","journal-title":"J. Clin. Pharm. Ther."},{"issue":"6","key":"10.1016\/j.cbi.2009.09.010_bib37","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1172\/JCI200318859","article-title":"A crucial role for thiol antioxidants in estrogen-deficiency bone loss","volume":"112","author":"Lean","year":"2003","journal-title":"J. Clin. Invest."},{"issue":"1","key":"10.1016\/j.cbi.2009.09.010_bib38","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1210\/en.2004-1058","article-title":"Tumor necrosis factor-alpha mediates osteopenia caused by depletion of antioxidants","volume":"146","author":"Jagger","year":"2005","journal-title":"Endocrinology"},{"issue":"6","key":"10.1016\/j.cbi.2009.09.010_bib39","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1007\/BF02743581","article-title":"The effect of melatonin on lipid peroxidation during radiotherapy in female rats","volume":"175","author":"Kaya","year":"1999","journal-title":"Strahlenther Onkol"},{"issue":"4","key":"10.1016\/j.cbi.2009.09.010_bib40","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/S0142-9612(99)00193-3","article-title":"Gamma irradiation of human bone allografts alters medullary lipids and releases toxic compounds for osteoblast-like cells","volume":"21","author":"Moreau","year":"2000","journal-title":"Biomaterials"},{"issue":"6","key":"10.1016\/j.cbi.2009.09.010_bib41","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1016\/S1043-6618(03)00226-3","article-title":"Protective effect of arabic gum against acetaminophen-induced hepatotoxicity in mice","volume":"48","author":"Gamal el-din","year":"2003","journal-title":"Pharmacol. Res."},{"issue":"1","key":"10.1016\/j.cbi.2009.09.010_bib42","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1034\/j.1600-079X.2003.00050.x","article-title":"Protective effects of melatonin, vitamin E and N-acetylcysteine against acetaminophen toxicity in mice: a comparative study","volume":"35","author":"Sener","year":"2003","journal-title":"J. Pineal Res."},{"issue":"1","key":"10.1016\/j.cbi.2009.09.010_bib43","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1002\/jat.1012","article-title":"Protective effects of MESNA (2-mercaptoethane sulphonate) against acetaminophen-induced hepatorenal oxidative damage in mice","volume":"25","author":"Sener","year":"2005","journal-title":"J. Appl. Toxicol."},{"key":"10.1016\/j.cbi.2009.09.010_bib44","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1038\/35041687","article-title":"Oxidants, oxidative stress and biology of ageing","volume":"408","author":"Finkel","year":"2000","journal-title":"Nature"},{"issue":"1\u20132","key":"10.1016\/j.cbi.2009.09.010_bib45","first-page":"1","article-title":"DNA damage of tumor-associated lymphocytes and total antioxidant capacity in cancerous patients","volume":"539","author":"Liu","year":"2003","journal-title":"Mutat. Res."},{"issue":"3","key":"10.1016\/j.cbi.2009.09.010_bib46","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1172\/JCI114485","article-title":"Oxygen-derived free radicals stimulate osteoclastic bone resorption in rodent bone in vitro and in vivo","volume":"85","author":"Garrett","year":"1990","journal-title":"J. Clin. Invest."},{"issue":"3","key":"10.1016\/j.cbi.2009.09.010_bib47","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/8756-3282(96)00177-9","article-title":"Hydrogen peroxide, but not superoxide, stimulates bone resorption in mouse calvariae","volume":"19","author":"Fraser","year":"1996","journal-title":"Bone"},{"issue":"4","key":"10.1016\/j.cbi.2009.09.010_bib48","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1016\/S0891-5849(01)00610-4","article-title":"Oxidative stress modulates osteoblastic differentiation of vascular and bone cells","volume":"31","author":"Mody","year":"2001","journal-title":"Free Radic. Biol. Med."},{"issue":"1","key":"10.1016\/j.cbi.2009.09.010_bib49","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.bbrc.2003.12.073","article-title":"Oxidative stress inhibits osteoblastic differentiation of bone cells by ERK and NF-kappaB","volume":"314","author":"Bai","year":"2004","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"11","key":"10.1016\/j.cbi.2009.09.010_bib50","doi-asserted-by":"crossref","first-page":"1285","DOI":"10.1038\/nm1197-1285","article-title":"Osteopetrosis in mice lacking NF-kappaB1 and NF-kappaB2","volume":"3","author":"Iotsova","year":"1997","journal-title":"Nat. Med."},{"issue":"1","key":"10.1016\/j.cbi.2009.09.010_bib51","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1006\/bbrc.2001.5747","article-title":"Association between oxidative stress and bone mineral density","volume":"288","author":"Basu","year":"2001","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"3","key":"10.1016\/j.cbi.2009.09.010_bib52","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1083\/jcb.126.3.765","article-title":"NADPH-oxidase expression and in situ production of superoxide by osteoclasts actively resorbing bone","volume":"126","author":"Steinbeck","year":"1994","journal-title":"J. Cell Biol."},{"issue":"12S","key":"10.1016\/j.cbi.2009.09.010_bib53","doi-asserted-by":"crossref","first-page":"2892","DOI":"10.1002\/1097-0142(20000615)88:12+<2892::AID-CNCR2>3.0.CO;2-Y","article-title":"Molecular mechanisms of osteolytic bone metastases","volume":"88","author":"Guise","year":"2000","journal-title":"Cancer"},{"issue":"1","key":"10.1016\/j.cbi.2009.09.010_bib54","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1080\/01635589909514744","article-title":"Induction of apoptosis in human breast cancer cells by tocopherols and tocotrienols","volume":"33","author":"Yu","year":"1999","journal-title":"Nutr. Cancer"},{"issue":"5","key":"10.1016\/j.cbi.2009.09.010_bib55","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1007\/s00280-004-0817-y","article-title":"Novel vitamin E analogue and 9-nitro-camptothecin administered as liposome aerosols decrease syngeneic mouse mammary tumor burden and inhibit metastasis","volume":"54","author":"Lawson","year":"2004","journal-title":"Cancer Chemother. Pharmacol."},{"issue":"1","key":"10.1016\/j.cbi.2009.09.010_bib56","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1359\/jbmr.2001.16.1.135","article-title":"C supplement use and bone mineral density in postmenopausal women","volume":"16","author":"Morton","year":"2001","journal-title":"J. Bone Miner. Res."},{"issue":"4","key":"10.1016\/j.cbi.2009.09.010_bib57","doi-asserted-by":"crossref","first-page":"1523","DOI":"10.1210\/jc.2002-021496","article-title":"Marked decrease in plasma antioxidants in aged osteoporotic women: results of a cross-sectional study","volume":"88","author":"Maggio","year":"2003","journal-title":"J. Clin. Endocrinol. Metab."},{"issue":"1\u20132","key":"10.1016\/j.cbi.2009.09.010_bib58","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.tox.2006.02.008","article-title":"Effects of melatonin and vitamin E on oxidative-antioxidative status in rats exposed to irradiation","volume":"222","author":"Yilmaz","year":"2006","journal-title":"Toxicology"},{"issue":"1","key":"10.1016\/j.cbi.2009.09.010_bib59","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1021\/ar030069m","article-title":"Dynamics of antioxidant action of vitamin E","volume":"37","author":"Niki","year":"2004","journal-title":"Acc. Chem. Res."},{"issue":"10","key":"10.1016\/j.cbi.2009.09.010_bib60","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.1096\/fasebj.13.10.1145","article-title":"Vitamin E: function and metabolism","volume":"13","author":"Brigelius-Flohe","year":"1999","journal-title":"Faseb J."},{"issue":"1","key":"10.1016\/j.cbi.2009.09.010_bib61","first-page":"120","article-title":"Hypoxia-induced angiogenesis during carcinogenesis","volume":"36","author":"Choi","year":"2003","journal-title":"J. Biochem. Mol. Biol."},{"issue":"9","key":"10.1016\/j.cbi.2009.09.010_bib62","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1111\/j.1440-1681.2005.04264.x","article-title":"Tocotrienol offers better protection than tocopherol from free radical-induced damage of rat bone","volume":"32","author":"Ahmad","year":"2005","journal-title":"Clin. Exp. Pharmacol. Physiol."}],"container-title":["Chemico-Biological Interactions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0009279709003913?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0009279709003913?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,14]],"date-time":"2025-09-14T13:20:09Z","timestamp":1757856009000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0009279709003913"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,12]]},"references-count":62,"journal-issue":{"issue":"2-3","published-print":{"date-parts":[[2009,12]]}},"alternative-id":["S0009279709003913"],"URL":"https:\/\/doi.org\/10.1016\/j.cbi.2009.09.010","relation":{},"ISSN":["0009-2797"],"issn-type":[{"value":"0009-2797","type":"print"}],"subject":[],"published":{"date-parts":[[2009,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effect of alpha tocopherol acetate in Walker 256\/B cells-induced oxidative damage in a rat model of breast cancer skeletal metastases","name":"articletitle","label":"Article Title"},{"value":"Chemico-Biological Interactions","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cbi.2009.09.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2009 Elsevier Ireland Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}