{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T20:14:47Z","timestamp":1792700087480,"version":"4.5.0"},"reference-count":62,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,11,1]],"date-time":"2019-11-01T00:00:00Z","timestamp":1572566400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,11,1]],"date-time":"2019-11-01T00:00:00Z","timestamp":1572566400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001407","name":"Department of Biotechnology, Ministry of Science and Technology, India","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001407","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001412","name":"Council of Scientific and Industrial Research, India","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001412","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Chemico-Biological Interactions"],"published-print":{"date-parts":[[2019,11]]},"DOI":"10.1016\/j.cbi.2019.108824","type":"journal-article","created":{"date-parts":[[2019,9,19]],"date-time":"2019-09-19T19:03:52Z","timestamp":1568919832000},"page":"108824","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":69,"special_numbering":"C","title":["Beneficial role of insect-derived bioactive components against inflammation and its associated complications (colitis and arthritis) and cancer"],"prefix":"10.1016","volume":"313","author":[{"given":"Prachurjya","family":"Dutta","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ravi Kumar","family":"Sahu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tapan","family":"Dey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manisha Datta","family":"Lahkar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prasenjit","family":"Manna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jatin","family":"Kalita","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"6","key":"10.1016\/j.cbi.2019.108824_bib1","doi-asserted-by":"crossref","first-page":"3670","DOI":"10.1016\/j.bbagen.2013.02.008","article-title":"Natural products: a continuing source of novel drug leads","volume":"1830","author":"Cragg","year":"2013","journal-title":"Biochim. Biophys. Acta"},{"issue":"7","key":"10.1016\/j.cbi.2019.108824_bib2","first-page":"261","article-title":"Can insects help to ease the problem of world food shortage?","volume":"6","author":"Meyer-Rochow","year":"1975","journal-title":"Search"},{"issue":"1","key":"10.1016\/j.cbi.2019.108824_bib3","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1024\/0300-9831\/a000050","article-title":"Chemical composition of Aspongopus nepalensis westwood 1837 (Hemiptera; pentatomidae), a common food insect of tribal people in Arunachal Pradesh (India)","volume":"81","author":"Chakravorty","year":"2011","journal-title":"Int. J. Vitam. Nutr. Res."},{"issue":"44","key":"10.1016\/j.cbi.2019.108824_bib4","doi-asserted-by":"crossref","first-page":"8420","DOI":"10.1021\/acs.jafc.6b03286","article-title":"In vitro iron availability from insects and sirloin beef","volume":"64","author":"Latunde-Dada","year":"2016","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.cbi.2019.108824_bib5","doi-asserted-by":"crossref","first-page":"1303","DOI":"10.1016\/S0271-5317(03)00132-5","article-title":"Nutritive value of non-mulberry and mulberry silkworm pupae and consumption pattern in Assam, India","volume":"23","author":"Mishra","year":"2003","journal-title":"Nutr. Res."},{"issue":"14","key":"10.1016\/j.cbi.2019.108824_bib6","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/jis\/14.1.14","article-title":"Nutritional and antinutritional composition of the five species of aquatic edible insects consumed in Manipur, India","volume":"14","author":"Shantibala","year":"2014","journal-title":"J. Insect Sci."},{"issue":"5","key":"10.1016\/j.cbi.2019.108824_bib7","first-page":"1","article-title":"Practices of entomophagy and entomotherapy by members of the Nyishi and Galo tribes, two ethnic groups of the state of Arunachal Pradesh (North-East India)","volume":"7","author":"Chakravorty","year":"2011","journal-title":"J. Ethnobiol. Ethnomed."},{"issue":"9","key":"10.1016\/j.cbi.2019.108824_bib8","first-page":"1","article-title":"Therapeutic arthropods and other, largely terrestrial, folk-medicinally important invertebrates: a comparative survey and review","volume":"13","author":"Meyer-Rochow","year":"2017","journal-title":"J. Ethnobiol. Ethnomed."},{"issue":"12","key":"10.1016\/j.cbi.2019.108824_bib9","first-page":"1575","article-title":"Bioprospecting with reference to medicinal insects and tribes in India: an overview","volume":"134","author":"Senthilkumar","year":"2008","journal-title":"Indian For."},{"issue":"12","key":"10.1016\/j.cbi.2019.108824_bib10","doi-asserted-by":"crossref","first-page":"1737","DOI":"10.1039\/c005319h","article-title":"Insects and their chemical weaponry: new potential for drug discovery","volume":"27","author":"Dossey","year":"2010","journal-title":"Nat. Prod. Rep."},{"key":"10.1016\/j.cbi.2019.108824_bib11","first-page":"1","volume":"vol 2014","year":"2014"},{"key":"10.1016\/j.cbi.2019.108824_bib12","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1016\/j.biopha.2017.08.094","article-title":"Antioxidant and glucose metabolizing potential of edible insect, Brachytrupes orientalis via modulating Nrf2\/AMPK\/GLUT4 signaling pathway","volume":"95","author":"Dutta","year":"2017","journal-title":"Biomed. Pharmacother."},{"issue":"5","key":"10.1016\/j.cbi.2019.108824_bib13","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1371\/journal.pone.0156107","article-title":"Antioxidant potential of vespa affinis L., a traditional edible insect species of North East India","volume":"11","author":"Dutta","year":"2016","journal-title":"PLoS One"},{"issue":"2","key":"10.1016\/j.cbi.2019.108824_bib14","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/j.bbamem.2012.10.028","article-title":"Insight into the antimicrobial activities of coprisin isolated from the dung beetle, Copris tripartitus, revealed by structure-activity relationships","volume":"1828","author":"Lee","year":"2013","journal-title":"Biochim. Biophys. Acta"},{"issue":"5","key":"10.1016\/j.cbi.2019.108824_bib15","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3390\/molecules21050616","article-title":"Anti-inflammatory applications of melittin, a major component of bee venom: detailed mechanism of action and adverse effects","volume":"21","author":"Lee","year":"2016","journal-title":"Molecules"},{"issue":"6","key":"10.1016\/j.cbi.2019.108824_bib16","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1016\/j.cell.2010.02.043","article-title":"Anti-inflammatory agents: present and future","volume":"140","author":"Dinarello","year":"2010","journal-title":"Cell"},{"issue":"2","key":"10.1016\/j.cbi.2019.108824_bib17","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/j.pmr.2005.12.012","article-title":"Nonsteroidal anti-inflammatory drugs","volume":"17","author":"Dugowson","year":"2006","journal-title":"Phys. Med. Rehabil. Clin. N. Am."},{"issue":"2","key":"10.1016\/j.cbi.2019.108824_bib18","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1038\/clpt.2008.204","article-title":"Risk of myocardial infarction and death associated with the use of nonsteroidal anti-inflammatory drugs (NSAIDs) among healthy individuals: a nationwide cohort study","volume":"85","author":"Fosbol","year":"2009","journal-title":"Clin. Pharmacol. Ther."},{"issue":"7","key":"10.1016\/j.cbi.2019.108824_bib19","doi-asserted-by":"crossref","first-page":"2146","DOI":"10.3390\/ph3072146","article-title":"Non-steroidal anti-inflammatory drugs: an overview of cardiovascular risks","volume":"3","author":"Meek","year":"2010","journal-title":"Pharmaceuticals (Basel)"},{"issue":"258209","key":"10.1016\/j.cbi.2019.108824_bib20","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2013\/258209","article-title":"Current perspectives in NSAID-induced gastropathy","volume":"2013","author":"Sinha","year":"2013","journal-title":"Mediat. Inflamm."},{"issue":"6","key":"10.1016\/j.cbi.2019.108824_bib21","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1093\/oxfordjournals.aje.a117469","article-title":"Nonsteroidal anti-inflammatory drugs and the incidence of hospitalizations for peptic ulcer disease in elderly persons","volume":"141","author":"Smalley","year":"1995","journal-title":"Am. J. Epidemiol."},{"key":"10.1016\/j.cbi.2019.108824_bib22","series-title":"World Cancer Report","author":"Stewart","year":"2003"},{"key":"10.1016\/j.cbi.2019.108824_bib23","volume":"vol 11","author":"Pazdur","year":"2008"},{"issue":"3","key":"10.1016\/j.cbi.2019.108824_bib24","doi-asserted-by":"crossref","first-page":"1351","DOI":"10.3390\/cancers3011351","article-title":"Cisplatin as an anti-tumor drug: cellular mechanisms of activity, drug resistance and induced side effects","volume":"15","author":"Florea","year":"2011","journal-title":"Cancers (Basel)"},{"issue":"2","key":"10.1016\/j.cbi.2019.108824_bib25","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/0378-8741(89)90062-7","article-title":"Medical uses of mylabris in ancient China and recent studies","volume":"26","author":"Wang","year":"1989","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.cbi.2019.108824_bib26","doi-asserted-by":"crossref","first-page":"S38","DOI":"10.1111\/j.1748-5967.2008.00173.x","article-title":"The utilization and industrialization of insect resources in China","volume":"38","author":"Zhang","year":"2008","journal-title":"Entomol. Res."},{"issue":"1","key":"10.1016\/j.cbi.2019.108824_bib27","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/j.jep.2012.02.016","article-title":"Antitumor effects and chemical compositions of Eupolyphaga sinensis Walker ethanol extract","volume":"141","author":"Ge","year":"2012","journal-title":"J. Ethnopharmacol."},{"issue":"5518","key":"10.1016\/j.cbi.2019.108824_bib28","first-page":"1","article-title":"Eupolyphaga sinensis walker displays inhibition on hepatocellular carcinoma through regulating cell growth and metastasis signaling","volume":"4","author":"Zhang","year":"2014","journal-title":"Sci. Rep."},{"issue":"22\u201324","key":"10.1016\/j.cbi.2019.108824_bib29","doi-asserted-by":"crossref","first-page":"1332","DOI":"10.1080\/15287394.2014.951591","article-title":"Anti-inflammatory effect of glycosaminoglycan derived from Gryllus bimaculatus (a type of cricket, insect) on adjuvant-treated chronic arthritis rat model","volume":"77","author":"Ahn","year":"2014","journal-title":"J. Toxicol. Environ. Health"},{"issue":"4","key":"10.1016\/j.cbi.2019.108824_bib30","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3390\/nu11040857","article-title":"The edible insect Gryllus bimaculatus protects against gut-derived inflammatory responses and liver damage in mice after acute alcohol exposure","volume":"11","author":"Hwang","year":"2019","journal-title":"Nutrients"},{"issue":"23","key":"10.1016\/j.cbi.2019.108824_bib31","doi-asserted-by":"crossref","first-page":"7826","DOI":"10.1016\/j.bmc.2006.07.063","article-title":"Antioxidant and anti-inflammatory activities of N-acetyldopamine dimers from Periostracum Cicadae","volume":"14","author":"Xu","year":"2006","journal-title":"Bioorg. Med. Chem."},{"issue":"3","key":"10.1016\/j.cbi.2019.108824_bib32","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1007\/s10753-009-9171-x","article-title":"Anti-inflammatory and immunomodulatory effects of Ulomoides dermestoides on induced pleurisy in rats and lymphoproliferation in vitro","volume":"33","author":"Santos","year":"2010","journal-title":"Inflammation"},{"issue":"7","key":"10.1016\/j.cbi.2019.108824_bib33","doi-asserted-by":"crossref","first-page":"3209","DOI":"10.1074\/jbc.M115.682856","article-title":"The insect peptide CopA3 increases colonic epithelial cell proliferation and mucosal barrier function to prevent inflammatory responses in the gut","volume":"291","author":"Kim","year":"2016","journal-title":"J. Biol. Chem."},{"issue":"4","key":"10.1016\/j.cbi.2019.108824_bib34","doi-asserted-by":"crossref","first-page":"4001","DOI":"10.3892\/mmr.2017.7087","article-title":"Bombyx mori hemocyte extract has anti-inflammatory effects on human phorbol myristate acetate-differentiated THP1 cells via TLR4-mediated suppression of the NF-kappaB signaling pathway","volume":"16","author":"Kim","year":"2017","journal-title":"Mol. Med. Rep."},{"issue":"1","key":"10.1016\/j.cbi.2019.108824_bib35","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1002\/arch.21193","article-title":"Anti-inflammatory activities of cecropin A and its mechanism of action","volume":"88","author":"Lee","year":"2015","journal-title":"Arch. Insect Biochem. Physiol."},{"issue":"48","key":"10.1016\/j.cbi.2019.108824_bib36","doi-asserted-by":"crossref","first-page":"41296","DOI":"10.1074\/jbc.M111.269225","article-title":"Structure and function of papiliocin with antimicrobial and anti-inflammatory activities isolated from the swallowtail butterfly, Papilio xuthus","volume":"286","author":"Kim","year":"2011","journal-title":"J. Biol. Chem."},{"issue":"556","key":"10.1016\/j.cbi.2019.108824_bib37","first-page":"1","article-title":"A potent anti-inflammatory peptide from the salivary glands of horsefly","volume":"8","author":"Wei","year":"2015","journal-title":"Parasites Vectors"},{"issue":"561","key":"10.1016\/j.cbi.2019.108824_bib38","first-page":"1","article-title":"A cecropin-like antimicrobial peptide with anti-inflammatory activity from the black fly salivary glands","volume":"8","author":"Wu","year":"2015","journal-title":"Parasites Vectors"},{"issue":"93","key":"10.1016\/j.cbi.2019.108824_bib39","first-page":"1","article-title":"Bioactivity of Samsum ant (Pachycondyla sennaarensis) venom against lipopolysaccharides through antioxidant and upregulation of Akt1 signaling in rats","volume":"11","author":"Ebaid","year":"2012","journal-title":"Lipids Health Dis."},{"issue":"1","key":"10.1016\/j.cbi.2019.108824_bib40","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12906-017-1748-6","article-title":"Natural products isolated from Tetragonula carbonaria cerumen modulate free radical-scavenging and 5-lipoxygenase activities in vitro","volume":"17","author":"Hamilton","year":"2017","journal-title":"BMC Complement Altern. Med."},{"issue":"2","key":"10.1016\/j.cbi.2019.108824_bib41","doi-asserted-by":"crossref","first-page":"171","DOI":"10.3109\/08923973.2015.1009996","article-title":"Evaluation of anti-inflammatory, anti-nociceptive, and anti-arthritic activities of Indian Apis dorsata bee venom in experimental animals: biochemical, histological, and radiological assessment","volume":"37","author":"Nipate","year":"2015","journal-title":"Immunopharmacol. Immunotoxicol."},{"issue":"5","key":"10.1016\/j.cbi.2019.108824_bib42","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1371\/journal.pone.0096825","article-title":"How the venom from the ectoparasitoid Wasp nasonia vitripennis exhibits anti-inflammatory properties on mammalian cell lines","volume":"9","author":"Danneels","year":"2014","journal-title":"PLoS One"},{"issue":"6978194","key":"10.1016\/j.cbi.2019.108824_bib43","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2017\/6978194","article-title":"Anti-inflammatory activity of crude venom isolated from parasitoid wasp, Bracon hebetor say","volume":"2017","author":"Saba","year":"2017","journal-title":"Mediat. Inflamm."},{"issue":"1","key":"10.1016\/j.cbi.2019.108824_bib44","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ijpharm.2016.06.120","article-title":"Effect of aqueous and particulate silk fibroin in a rat model of experimental colitis","volume":"511","author":"Rodriguez-Nogales","year":"2016","journal-title":"Int. J. Pharm."},{"issue":"10","key":"10.1016\/j.cbi.2019.108824_bib45","doi-asserted-by":"crossref","first-page":"4850","DOI":"10.1128\/AAC.00177-11","article-title":"The insect peptide coprisin prevents Clostridium difficile-mediated acute inflammation and mucosal damage through selective antimicrobial activity","volume":"55","author":"Kang","year":"2011","journal-title":"Antimicrob. Agents Chemother."},{"issue":"7","key":"10.1016\/j.cbi.2019.108824_bib46","first-page":"1","article-title":"JNK pathway is involved in the inhibition of inflammatory target gene expression and NF-kappaB activation by melittin","volume":"5","author":"Park","year":"2008","journal-title":"J. Inflamm."},{"issue":"11","key":"10.1016\/j.cbi.2019.108824_bib47","doi-asserted-by":"crossref","first-page":"3504","DOI":"10.1002\/art.20626","article-title":"Antiarthritic effect of bee venom: inhibition of inflammation mediator generation by suppression of NF-kappaB through interaction with the p50 subunit","volume":"50","author":"Park","year":"2004","journal-title":"Arthritis Rheum."},{"issue":"2","key":"10.1016\/j.cbi.2019.108824_bib48","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/j.bcp.2006.09.023","article-title":"Melittin inhibits inflammatory target gene expression and mediator generation via interaction with IkappaB kinase","volume":"73","author":"Park","year":"2007","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.cbi.2019.108824_bib49","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.fitote.2014.03.004","article-title":"Isocoumarins from American cockroach (Periplaneta americana) and their cytotoxic activities","volume":"95","author":"Luo","year":"2014","journal-title":"Fitoterapia"},{"issue":"7","key":"10.1016\/j.cbi.2019.108824_bib50","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.1016\/j.fitote.2012.06.005","article-title":"New isocoumarins and alkaloid from Chinese insect medicine, Eupolyphaga sinensis Walker","volume":"83","author":"Jiang","year":"2012","journal-title":"Fitoterapia"},{"issue":"4","key":"10.1016\/j.cbi.2019.108824_bib51","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1139\/bcb-2013-0002","article-title":"A novel protein from Eupolyphaga sinensis inhibits adhesion, migration, and invasion of human lung cancer A549 cells","volume":"91","author":"Wang","year":"2013","journal-title":"Biochem. Cell Biol."},{"key":"10.1016\/j.cbi.2019.108824_bib52","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.fitote.2016.09.005","article-title":"Compounds from Polyphaga plancyi and their inhibitory activities against JAK3 and DDR1 kinases","volume":"114","author":"Zhu","year":"2016","journal-title":"Fitoterapia"},{"issue":"8","key":"10.1016\/j.cbi.2019.108824_bib53","doi-asserted-by":"crossref","first-page":"1256","DOI":"10.1021\/np0402367","article-title":"Antineoplastic agents. 553. The Texas grasshopper Brachystola magna","volume":"68","author":"Pettit","year":"2005","journal-title":"J. Nat. Prod."},{"issue":"8934794","key":"10.1016\/j.cbi.2019.108824_bib54","first-page":"1","article-title":"Antiproliferative and proapoptotic effects of a protein component purified from Aspongopus chinensis Dallas on cancer cells in vitro and in vivo","volume":"2019","author":"Tan","year":"2019","journal-title":"Evid Based Complement Alternat Med"},{"key":"10.1016\/j.cbi.2019.108824_bib55","doi-asserted-by":"crossref","first-page":"245","DOI":"10.3892\/ijo.2014.2428","article-title":"Cantharidin induces apoptosis of H460 human lung cancer cells through mitochondria-dependent pathways","volume":"45","author":"Hsia","year":"2014","journal-title":"Int. J. Oncol."},{"issue":"1","key":"10.1016\/j.cbi.2019.108824_bib56","doi-asserted-by":"crossref","first-page":"2393","DOI":"10.3892\/ijo.2014.2689","article-title":"Cantharidin induces G2\/M phase arrest by inhibition of Cdc25c and Cyclin A and triggers apoptosis through reactive oxygen species and the mitochondria-dependent pathways of A375.S2 human melanoma cells","volume":"45","author":"Hsiao","year":"2014","journal-title":"Int. J. Oncol."},{"issue":"2","key":"10.1016\/j.cbi.2019.108824_bib57","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1007\/s12272-014-0383-8","article-title":"Cantharidin inhibits angiogenesis by suppressing VEGF-induced JAK1\/STAT3, ERK and AKT signaling pathways","volume":"38","author":"Wang","year":"2015","journal-title":"Arch Pharm. Res. (Seoul)"},{"issue":"3","key":"10.1016\/j.cbi.2019.108824_bib58","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1097\/00001813-200503000-00008","article-title":"Inhibitory effect of norcantharidin, a derivative compound from blister beetles, on tumor invasion and metastasis in CT26 colorectal adenocarcinoma cells","volume":"16","author":"Chen","year":"2005","journal-title":"Anti Canccer Drugs"},{"issue":"2","key":"10.1016\/j.cbi.2019.108824_bib59","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1016\/j.bbrc.2014.04.035","article-title":"A novel cantharidin analog N-benzylcantharidinamide reduces the expression of MMP-9 and invasive potentials of Hep3B via inhibiting cytosolic translocation of HuR","volume":"447","author":"Lee","year":"2014","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"3","key":"10.1016\/j.cbi.2019.108824_bib60","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1007\/s10565-011-9206-6","article-title":"Bioactive component, cantharidin from Mylabris cichorii and its antitumor activity against Ehrlich ascites carcinoma","volume":"28","author":"Verma","year":"2012","journal-title":"Cell Biol. Toxicol."},{"issue":"3","key":"10.1016\/j.cbi.2019.108824_bib61","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1016\/j.jep.2013.05.032","article-title":"Antitumor effect of blister beetles: an ethno-medicinal practice in Karbi community and its experimental evaluation against a murine malignant tumor model","volume":"148","author":"Verma","year":"2013","journal-title":"J. Ethnopharmacol."},{"issue":"3","key":"10.1016\/j.cbi.2019.108824_bib62","doi-asserted-by":"crossref","first-page":"1177","DOI":"10.1016\/j.etap.2014.04.010","article-title":"Eupolyphaga sinensis Walker inhibits human chronic myeloid leukemia cell K562 growth by inducing G2-M phase cell cycle arrest and targeting EGFR signaling pathway and in S180 tumor-bearing mice","volume":"37","author":"Dai","year":"2014","journal-title":"Environ. Toxicol. Pharmacol."}],"container-title":["Chemico-Biological Interactions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S000927971930746X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S000927971930746X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,14]],"date-time":"2025-09-14T13:55:16Z","timestamp":1757858116000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S000927971930746X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,11]]},"references-count":62,"alternative-id":["S000927971930746X"],"URL":"https:\/\/doi.org\/10.1016\/j.cbi.2019.108824","relation":{},"ISSN":["0009-2797"],"issn-type":[{"value":"0009-2797","type":"print"}],"subject":[],"published":{"date-parts":[[2019,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Beneficial role of insect-derived bioactive components against inflammation and its associated complications (colitis and arthritis) and cancer","name":"articletitle","label":"Article Title"},{"value":"Chemico-Biological Interactions","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cbi.2019.108824","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"108824"}}