{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T10:41:25Z","timestamp":1793788885530,"version":"4.6.1"},"reference-count":54,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,2,17]],"date-time":"2024-02-17T00:00:00Z","timestamp":1708128000000},"content-version":"vor","delay-in-days":322,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004916","name":"Fundacao de Amparo a Pesquisa do Estado do Amazonas","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004916","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Chemico-Biological Interactions"],"published-print":{"date-parts":[[2023,4]]},"DOI":"10.1016\/j.cbi.2023.110405","type":"journal-article","created":{"date-parts":[[2023,2,14]],"date-time":"2023-02-14T15:25:21Z","timestamp":1676388321000},"page":"110405","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":11,"special_numbering":"C","title":["Malathion alters the transcription of target genes of the tumour suppressor tp53 and cancerous processes in Colossoma macropomum: Mechanisms of DNA damage response, oxidative stress and apoptosis"],"prefix":"10.1016","volume":"374","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4718-3188","authenticated-orcid":false,"given":"Samara Silva","family":"de Souza","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaqueline Cust\u00f3dio","family":"da Costa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Grazyelle Sebrenski","family":"da Silva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7038-5266","authenticated-orcid":false,"given":"Vera Maria Fonseca","family":"de Almeida-Val","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cbi.2023.110405_bib1","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1007\/s13593-021-00742-8","article-title":"Pesticide-free agriculture as a new paradigm for research","volume":"42","author":"Jacquet","year":"2022","journal-title":"Agron. Sustain. Dev."},{"key":"10.1016\/j.cbi.2023.110405_bib2","volume":"vol. 12","year":"2015"},{"key":"10.1016\/j.cbi.2023.110405_bib3","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1007\/BF01688646","article-title":"Assimilation of malathion in the Indian river estuary, Florida","volume":"47","author":"Wang","year":"1991","journal-title":"Bull. Environ. Contam. Toxicol."},{"key":"10.1016\/j.cbi.2023.110405_bib4","doi-asserted-by":"crossref","first-page":"2649","DOI":"10.1897\/03-436","article-title":"Persistence of selected organophosphate and carbamate insecticides in waters from a coastal watershed","volume":"23","author":"Bondarenko","year":"2004","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.cbi.2023.110405_bib5","doi-asserted-by":"crossref","first-page":"9992","DOI":"10.1038\/s41598-022-13216-y","article-title":"Risk assessment of glyphosate and malathion pollution and their potential impact on Oreochromis niloticus: role of organic selenium supplementation","volume":"12","author":"Hassan","year":"2022","journal-title":"Sci. Rep."},{"key":"10.1016\/j.cbi.2023.110405_bib6","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2021.132789","article-title":"A global systematic review of the concentrations of Malathion in water matrices: meta-analysis, and probabilistic risk assessment","volume":"291","author":"Vasseghian","year":"2022","journal-title":"Chemosphere"},{"key":"10.1016\/j.cbi.2023.110405_bib7","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.chemosphere.2013.02.054","article-title":"Effects of landuse and precipitation on pesticides and water quality in playa lakes of the southern high plains","volume":"92","author":"Anderson","year":"2013","journal-title":"Chemosphere"},{"key":"10.1016\/j.cbi.2023.110405_bib8","doi-asserted-by":"crossref","first-page":"8629","DOI":"10.1007\/s11356-014-4016-z","article-title":"Spatial distribution and partitioning of organophosphates pesticide in water and sediment from Sarno River and Estuary, Southern Italy","volume":"22","author":"Montuori","year":"2015","journal-title":"Environ. Sci. Pollut. Res."},{"key":"10.1016\/j.cbi.2023.110405_bib9","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1007\/s10661-016-5612-9","article-title":"The occurrence and risk assessment of five organophosphorus pesticides in river water from Shangyu, China","volume":"188","author":"Chen","year":"2016","journal-title":"Environ. Monit. Assess."},{"key":"10.1016\/j.cbi.2023.110405_bib10","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1007\/s10661-017-5956-9","article-title":"Pesticide survey in water and suspended solids from the Uruguay River Basin, Argentina","volume":"189","author":"Williman","year":"2017","journal-title":"Environ. Monit. Assess."},{"key":"10.1016\/j.cbi.2023.110405_bib11","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2021.132821","article-title":"Ecological risk assessment of pesticides in urban streams of the Brazilian Amazon","volume":"291","author":"Rico","year":"2022","journal-title":"Chemosphere"},{"key":"10.1016\/j.cbi.2023.110405_bib12","doi-asserted-by":"crossref","first-page":"2925","DOI":"10.1021\/es305058y","article-title":"Interactive neurobehavioral toxicity of diazinon, malathion, and ethoprop to juvenile coho salmon","volume":"47","author":"Laetz","year":"2013","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.cbi.2023.110405_bib13","doi-asserted-by":"crossref","DOI":"10.1016\/j.marpolbul.2022.113336","article-title":"The synergistic effect of microplastic and malathion exposure on fiddler crab Minuca ecuadoriensis microplastic bioaccumulation and survival","volume":"175","author":"Villegas","year":"2022","journal-title":"Mar. Pollut. Bull."},{"key":"10.1016\/j.cbi.2023.110405_bib14","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/j.ecoenv.2019.01.085","article-title":"High temperature aggravates the effects of pesticides in goldfish","volume":"172","author":"Jacquin","year":"2019","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.cbi.2023.110405_bib15","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1080\/02772248909357489","article-title":"Bioconcentration and excretion of diazinon, IBP, malathion and fenitrothion by willow shiner","volume":"24","author":"Tsuda","year":"1989","journal-title":"Toxicol. Environ. Chem."},{"key":"10.1016\/j.cbi.2023.110405_bib16","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1016\/S0045-6535(97)00180-X","article-title":"Acute toxicity, accumulation and excretion of organophosphorous insecticides and their oxidation products in killifish","volume":"35","author":"Tsuda","year":"1997","journal-title":"Chemosphere"},{"key":"10.1016\/j.cbi.2023.110405_bib17","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2019.05.081","article-title":"DNA damage, acetylcholinesterase activity, and hematological responses in rainbow trout exposed to the organophosphate malathion","volume":"182","author":"Alavinia","year":"2019","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.cbi.2023.110405_bib18","article-title":"Temporal exposure to malathion: biochemical changes in the Amazonian fish tambaqui","volume":"241","author":"Souza","year":"2021","journal-title":"Colossoma macropomum. Aquat. Toxicol."},{"key":"10.1016\/j.cbi.2023.110405_bib19","article-title":"Severe damages caused by Malathion exposure in Colossoma macropomum","volume":"205","author":"Souza","year":"2020","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.cbi.2023.110405_bib20","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1007\/s00244-009-9354-3","article-title":"Investigation of the genotoxicity of malathion to freshwater teleost fish Channa punctatus (bloch) using the micronucleus test and comet assay","volume":"58","author":"Kumar","year":"2010","journal-title":"Arch. Environ. Contam. Toxicol."},{"key":"10.1016\/j.cbi.2023.110405_bib21","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.cbpc.2019.04.010","article-title":"Gene expression, genotoxicity, and physiological responses in an Amazonian fish, Colossoma macropomum (CUVIER 1818), exposed to Roundup\u00ae and subsequent acute hypoxia","volume":"222","author":"Silva","year":"2019","journal-title":"Comp. Biochem. Physiol. C Toxicol. Pharmacol."},{"key":"10.1016\/j.cbi.2023.110405_bib22","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/j.fsi.2018.08.060","article-title":"Impaired immune function and structural integrity in the gills of common carp (Cyprinus carpio L.) caused by chlorpyrifos exposure: through oxidative stress and apoptosis","volume":"86","author":"Jiao","year":"2019","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.cbi.2023.110405_bib23","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/j.aquatox.2015.11.014","article-title":"Early life exposure to a rodent carcinogen propiconazole fungicide induces oxidative stress and hepatocarcinogenesis in medaka fish","volume":"170","author":"Tu","year":"2016","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.cbi.2023.110405_bib24","doi-asserted-by":"crossref","first-page":"1797","DOI":"10.1007\/s10529-012-0980-x","article-title":"Characterization of the tilapia p53 gene and its role in chemical-induced apoptosis","volume":"34","author":"Mai","year":"2012","journal-title":"Biotechnol. Lett."},{"key":"10.1016\/j.cbi.2023.110405_bib25","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1016\/j.fsi.2019.07.022","article-title":"Chlorpyrifos induced oxidative stress to promote apoptosis and autophagy through the regulation of miR-19a-AMPK axis in common carp","volume":"93","author":"Zhang","year":"2019","journal-title":"Fish Shellfish Immunol."},{"issue":"2013","key":"10.1016\/j.cbi.2023.110405_bib26","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/j.aquatox.2012.12.018","article-title":"Copper induced upregulation of apoptosis related genes in zebrafish (Danio rerio) gill","volume":"128\u2013129","author":"Luzio","year":"2013","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.cbi.2023.110405_bib27","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1590\/1678-4685-gmb-2018-0084","article-title":"Ecophysiology, genotoxicity, histopathology, and gene responses of naphthalene injected Colossoma macropomum (Cuvier, 1818) exposed to hypoxia","volume":"42","author":"Souza","year":"2019","journal-title":"Genet. Mol. Biol."},{"key":"10.1016\/j.cbi.2023.110405_bib28","doi-asserted-by":"crossref","first-page":"1306","DOI":"10.1038\/nm1320","article-title":"The antioxidant function of the p53 tumor suppressor","volume":"11","author":"Sablina","year":"2005","journal-title":"Nat. Med."},{"key":"10.1016\/j.cbi.2023.110405_bib29","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2018.08.070","article-title":"Atrazine hinders PMA-induced neutrophil extracellular traps in carp via the promotion of apoptosis and inhibition of ROS burst, autophagy, and glycolysis","volume":"243","author":"Wang","year":"2018","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.cbi.2023.110405_bib30","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1016\/j.chemosphere.2013.01.037","article-title":"Effects of fluoride on liver apoptosis and Bcl-2, Bax protein expression in freshwater teleost, Cyprinus carpio","volume":"91","author":"Cao","year":"2013","journal-title":"Chemosphere"},{"key":"10.1016\/j.cbi.2023.110405_bib31","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.ygeno.2019.06.023","article-title":"Gene networks and toxicity\/detoxification pathways in juvenile largemouth bass (Micropterus salmoides) liver induced by acute lead stress","volume":"112","author":"Qian","year":"2020","journal-title":"Genomics"},{"key":"10.1016\/j.cbi.2023.110405_bib32","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.aquatox.2012.10.007","article-title":"Gene transcription and biomarker responses in the clam Ruditapes philippinarum after exposure to ibuprofen","volume":"126","author":"Milan","year":"2012","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.cbi.2023.110405_bib33","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.cbpc.2014.03.005","article-title":"Transcriptional responses in Atlantic salmon (Salmo salar) exposed to deltamethrin, alone or in combination with azamethiphos","volume":"162","author":"Olsvik","year":"2014","journal-title":"Comp. Biochem. Physiol. C Toxicol. Pharmacol."},{"key":"10.1016\/j.cbi.2023.110405_bib34","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1089\/zeb.2016.1259","article-title":"Roundup in zebrafish: effects on oxidative status and gene expression","volume":"13","author":"Velasques","year":"2016","journal-title":"Zebrafish"},{"key":"10.1016\/j.cbi.2023.110405_bib35","doi-asserted-by":"crossref","DOI":"10.1016\/j.jtherbio.2019.102487","article-title":"How will farmed populations of freshwater fish deal with the extreme climate scenario in 2100? Transcriptional responses of Colossoma macropomum from two Brazilian climate regions","volume":"89","author":"F\u00e9-Gon\u00e7alves","year":"2020","journal-title":"J. Therm. Biol."},{"key":"10.1016\/j.cbi.2023.110405_bib36","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using realtime quantitative PCR and the 2\u2212\u0394\u0394CT method","volume":"25","author":"Livak","year":"2001","journal-title":"Methods"},{"key":"10.1016\/j.cbi.2023.110405_bib37","first-page":"140","article-title":"p53 gene expression is modulated by endocrine disrupting chemicals in the hermaphroditic fish, Kryptolebias marmoratus","volume":"147","author":"Lee","year":"2008","journal-title":"Comp. Biochem. Physiol. C Toxicol. Pharmacol."},{"key":"10.1016\/j.cbi.2023.110405_bib38","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1016\/j.chemosphere.2010.09.072","article-title":"Cypermethrin has the potential to induce hepatic oxidative stress, DNA damage and apoptosis in adult zebrafish (Danio rerio)","volume":"82","author":"Jin","year":"2011","journal-title":"Chemosphere"},{"key":"10.1016\/j.cbi.2023.110405_bib39","doi-asserted-by":"crossref","first-page":"3951","DOI":"10.1007\/s00018-014-1666-4","article-title":"Functional interplay between ATM\/ATR-mediated DNA damage response and DNA repair pathways in oxidative","volume":"71","author":"Yan","year":"2014","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.cbi.2023.110405_bib40","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/j.aquatox.2010.07.025","article-title":"Acute acidic exposure induces p53-mediated oxidative stress and DNA damage in tilapia (Oreochromis niloticus) blood cells","volume":"100","author":"Mai","year":"2010","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.cbi.2023.110405_bib41","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2020.128277","article-title":"Oxidative stress, cell cycle arrest, DNA damage and apoptosis in the mud crab (Scylla paramamosain) induced by cadmium exposure","volume":"263","author":"Cheng","year":"2021","journal-title":"Chemosphere"},{"key":"10.1016\/j.cbi.2023.110405_bib42","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2020.143831","article-title":"Immune, inflammatory, autophagic and DNA damage responses to long-term H2O2 exposure in different tissues of common carp (Cyprinus carpio)","volume":"757","author":"Jia","year":"2021","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.cbi.2023.110405_bib43","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1016\/j.fsi.2014.09.037","article-title":"Embryonic exposure to carbendazim induces the transcription of genes related to apoptosis, immunotoxicity and endocrine disruption in zebrafish (Danio rerio)","volume":"41","author":"Jiang","year":"2014","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.cbi.2023.110405_bib44","doi-asserted-by":"crossref","first-page":"1513","DOI":"10.1007\/s10646-012-0905-4","article-title":"Zebrafish (Danio rerio) life-cycle exposure to chronic low doses of ethinylestradiol modulates p53 gene transcription within the gonads, but not NER pathways","volume":"21","author":"Soares","year":"2012","journal-title":"Ecotoxicology"},{"key":"10.1016\/j.cbi.2023.110405_bib45","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.aquatox.2017.11.001","article-title":"Oxidative stress, cell cycle arrest, DNA damage and apoptosis in adult zebrafish (Danio rerio) induced by tris(1,3-dichloro-2-propyl) phosphate","volume":"194","author":"Chen","year":"2018","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.cbi.2023.110405_bib46","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1038\/s41419-018-0403-6","article-title":"MiR-16-5p targets SESN1 to regulate the p53 signaling pathway, affecting myoblast proliferation and apoptosis, and is involved in myoblast differentiation","volume":"9","author":"Cai","year":"2018","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.cbi.2023.110405_bib47","doi-asserted-by":"crossref","first-page":"1679","DOI":"10.1089\/ars.2010.3530","article-title":"Stress-responsive sestrins link p53 with redox regulation and mammalian target of rapamycin signaling","volume":"15","author":"Budanov","year":"2011","journal-title":"Antioxidants Redox Signal."},{"key":"10.1016\/j.cbi.2023.110405_bib48","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/j.cbpc.2007.11.006","article-title":"Modulatory effect of environmental endocrine disruptors on N-ras oncogene expression in the hermaphroditic fish, Kryptolebias marmoratus","volume":"147","author":"Lee","year":"2008","journal-title":"Comp. Biochem. Physiol. C Toxicol. Pharmacol."},{"key":"10.1016\/j.cbi.2023.110405_bib49","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1016\/j.cbpc.2008.10.102","article-title":"Expression of R-ras oncogenes in the hermaphroditic fish Kryptolebias marmoratus, exposed to endocrine disrupting chemicals","volume":"149","author":"Rhee","year":"2009","journal-title":"Comp. Biochem. Physiol. C Toxicol. Pharmacol."},{"key":"10.1016\/j.cbi.2023.110405_bib50","doi-asserted-by":"crossref","DOI":"10.1242\/jeb.163709","article-title":"Hypoxia-inducible transcription factors in fish: expression, function and interconnection with the circadian clock","volume":"221","author":"Pelster","year":"2018","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.cbi.2023.110405_bib51","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1590\/1678-4685-gmb-2016-0066","article-title":"Ras oncogene and Hypoxia-inducible factor-1 alpha (hif-1\u03b1) expression in the Amazon fish Colossoma macropomum (Cuvier, 1818) exposed to benzo[a]pyrene","volume":"40","author":"Silva","year":"2017","journal-title":"Genet. Mol. Biol."},{"key":"10.1016\/j.cbi.2023.110405_bib52","doi-asserted-by":"crossref","DOI":"10.1016\/j.aquatox.2019.105325","article-title":"Sublethal exposure to copper supresses the ability to acclimate to hypoxia in a model fish species","volume":"217","author":"Fitzgerald","year":"2019","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.cbi.2023.110405_bib53","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.18632\/oncotarget.27521","article-title":"Investigation of the role of VHL-HIF signaling in DNA repair and apoptosis in zebrafish","volume":"11","author":"Kim","year":"2020","journal-title":"Oncotarget"},{"key":"10.1016\/j.cbi.2023.110405_bib54","doi-asserted-by":"crossref","first-page":"1429","DOI":"10.1007\/s10695-021-00989-8","article-title":"Effects of acute hypoxia and reoxygenation on oxygen sensors, respiratory metabolism, oxidative stress, and apoptosis in hybrid yellow catfsh \u201cHuangyou-1.\u201d","volume":"47","author":"Pei","year":"2021","journal-title":"Fish Physiol. Biochem."}],"container-title":["Chemico-Biological Interactions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0009279723000728?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0009279723000728?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,1,8]],"date-time":"2025-01-08T15:36:11Z","timestamp":1736350571000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0009279723000728"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4]]},"references-count":54,"alternative-id":["S0009279723000728"],"URL":"https:\/\/doi.org\/10.1016\/j.cbi.2023.110405","relation":{},"ISSN":["0009-2797"],"issn-type":[{"value":"0009-2797","type":"print"}],"subject":[],"published":{"date-parts":[[2023,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Malathion alters the transcription of target genes of the tumour suppressor tp53 and cancerous processes in Colossoma macropomum: Mechanisms of DNA damage response, oxidative stress and apoptosis","name":"articletitle","label":"Article Title"},{"value":"Chemico-Biological Interactions","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cbi.2023.110405","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"110405"}}