{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T18:19:20Z","timestamp":1763749160875,"version":"3.44.0"},"reference-count":29,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,2,28]],"date-time":"2025-02-28T00:00:00Z","timestamp":1740700800000},"content-version":"am","delay-in-days":333,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000053","name":"National Eye Institute","doi-asserted-by":"publisher","award":["EY028147"],"award-info":[{"award-number":["EY028147"]}],"id":[{"id":"10.13039\/100000053","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100001818","name":"Research to Prevent Blindness","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100001818","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Chemico-Biological Interactions"],"published-print":{"date-parts":[[2024,4]]},"DOI":"10.1016\/j.cbi.2024.110905","type":"journal-article","created":{"date-parts":[[2024,2,17]],"date-time":"2024-02-17T04:54:19Z","timestamp":1708145659000},"page":"110905","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["High incidence of sebaceous gland inflammation in aldose reductase-deficient mice"],"prefix":"10.1016","volume":"392","author":[{"given":"Anjali","family":"Mandava","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Binhan","family":"Pham","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michelle","family":"Pedler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Biehuoy","family":"Shieh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hari","family":"Gopalakrishnan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6900-4240","authenticated-orcid":false,"given":"J. Mark","family":"Petrash","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.cbi.2024.110905_bib1","doi-asserted-by":"crossref","DOI":"10.1155\/2013\/343560","article-title":"Pathophysiology of diabetic retinopathy","author":"Tarr","year":"2013","journal-title":"ISRN ophthalmology"},{"key":"10.1016\/j.cbi.2024.110905_bib2","doi-asserted-by":"crossref","DOI":"10.1167\/iovs.13-12979","article-title":"Effects of diabetes on the eye","volume":"54","author":"Lutty","year":"2013","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.cbi.2024.110905_bib3","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1016\/S0161-6420(85)33877-0","article-title":"Prevalence of cataracts in a population-based study of persons with diabetes mellitus","volume":"92","author":"Klein","year":"1985","journal-title":"Ophthalmology"},{"key":"10.1016\/j.cbi.2024.110905_bib4","doi-asserted-by":"crossref","DOI":"10.1155\/2010\/608751","article-title":"Diabetic cataract-pathogenesis, epidemiology and treatment","author":"Pollreisz","year":"2010","journal-title":"J Ophthalmol"},{"key":"10.1016\/j.cbi.2024.110905_bib5","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1038\/414813a","article-title":"Biochemistry and molecular cell biology of diabetic complications","volume":"414","author":"Brownlee","year":"2001","journal-title":"Nature"},{"key":"10.1016\/j.cbi.2024.110905_bib6","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1096\/fasebj.13.1.23","article-title":"Contributions of polyol pathway to oxidative stress in diabetic cataract","volume":"13","author":"Lee","year":"1999","journal-title":"Faseb. J."},{"key":"10.1016\/j.cbi.2024.110905_bib7","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/j.cbi.2014.12.017","article-title":"Aldose reductase expression as a risk factor for cataract","volume":"234","author":"Snow","year":"2015","journal-title":"Chem. Biol. Interact."},{"key":"10.1016\/j.cbi.2024.110905_bib8","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1007\/BF00400627","article-title":"Acute onset of diabetic pathological changes in transgenic mice with human aldose reductase cDNA","volume":"38","author":"Yamaoka","year":"1995","journal-title":"Diabetologia"},{"key":"10.1016\/j.cbi.2024.110905_bib9","doi-asserted-by":"crossref","DOI":"10.3390\/metabo11070450","article-title":"Diabetes-independent retinal phenotypes in an aldose reductase transgenic mouse model","volume":"11","author":"Petrash","year":"2021","journal-title":"Metabolites"},{"key":"10.1016\/j.cbi.2024.110905_bib10","doi-asserted-by":"crossref","first-page":"3119","DOI":"10.2337\/diabetes.54.11.3119","article-title":"Aldose reductase deficiency prevents diabetes-induced blood-retinal barrier breakdown, apoptosis, and glial reactivation in the retina of db\/db mice","volume":"54","author":"Cheung","year":"2005","journal-title":"Diabetes"},{"key":"10.1016\/j.cbi.2024.110905_bib11","article-title":"Deletion of aldose reductase from mice inhibits diabetes-induced retinal capillary degeneration and superoxide generation","volume":"8","author":"Tang","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.cbi.2024.110905_bib12","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/j.cbi.2011.02.005","article-title":"Aldose reductase-mediated induction of epithelium-to-mesenchymal transition (EMT) in lens","volume":"191","author":"Zablocki","year":"2011","journal-title":"Chem. Biol. Interact."},{"key":"10.1016\/j.cbi.2024.110905_bib13","doi-asserted-by":"crossref","first-page":"3591","DOI":"10.1167\/iovs.18-23935","article-title":"Aldose reductase inhibition prevents development of posterior capsular opacification in an in vivo model of cataract surgery","volume":"59","author":"Zukin","year":"2018","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.cbi.2024.110905_bib14","doi-asserted-by":"crossref","first-page":"801","DOI":"10.2337\/diab.42.6.801","article-title":"Hyperglycemic pseudohypoxia and diabetic complications","volume":"42","author":"Williamson","year":"1993","journal-title":"Diabetes"},{"key":"10.1016\/j.cbi.2024.110905_bib15","doi-asserted-by":"crossref","first-page":"2526","DOI":"10.1681\/ASN.2013080901","article-title":"Endogenous fructose production and fructokinase activation mediate renal injury in diabetic nephropathy","volume":"25","author":"Lanaspa","year":"2014","journal-title":"J. Am. Soc. Nephrol."},{"key":"10.1016\/j.cbi.2024.110905_bib16","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/j.cbi.2017.01.017","article-title":"Influence of aldose reductase on epithelial-to-mesenchymal transition signaling in lens epithelial cells","volume":"276","author":"Chang","year":"2017","journal-title":"Chem. Biol. Interact."},{"key":"10.1016\/j.cbi.2024.110905_bib17","series-title":"Comparative Anatomy and Histology","first-page":"335","article-title":"Male reproductive System","author":"Knoblaugh","year":"2018"},{"key":"10.1016\/j.cbi.2024.110905_bib18","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1038\/cr.2017.81","article-title":"One-step generation of complete gene knockout mice and monkeys by CRISPR\/Cas9-mediated gene editing with multiple sgRNAs","volume":"27","author":"Zuo","year":"2017","journal-title":"Cell Res."},{"key":"10.1016\/j.cbi.2024.110905_bib19","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.canlet.2019.01.017","article-title":"CRISPR-Cas9 for cancer therapy: opportunities and challenges","volume":"447","author":"Chen","year":"2019","journal-title":"Cancer Lett."},{"key":"10.1016\/j.cbi.2024.110905_bib20","doi-asserted-by":"crossref","first-page":"3478","DOI":"10.1093\/hmg\/ddac128","article-title":"Modelling autosomal dominant optic atrophy associated with OPA1 variants in iPSC-derived retinal ganglion cells","volume":"31","author":"Sladen","year":"2022","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.cbi.2024.110905_bib21","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1007\/s12272-021-01343-5","article-title":"Aldose Reductase: a cause and a potential target for the treatment of diabetic complications","volume":"44","author":"Thakur","year":"2021","journal-title":"Arch Pharm. Res. (Seoul)"},{"key":"10.1016\/j.cbi.2024.110905_bib22","doi-asserted-by":"crossref","first-page":"5840","DOI":"10.1128\/MCB.20.16.5840-5846.2000","article-title":"Aldose reductase-deficient mice develop nephrogenic diabetes insipidus","volume":"20","author":"Ho","year":"2000","journal-title":"Mol. Cell Biol."},{"key":"10.1016\/j.cbi.2024.110905_bib23","doi-asserted-by":"crossref","first-page":"16810","DOI":"10.1016\/S0021-9258(19)84778-6","article-title":"Osmotic regulation of aldose reductase protein synthesis in renal medullary cells","volume":"264","author":"Moriyama","year":"1989","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.cbi.2024.110905_bib24","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1080\/15548627.2021.1966716","article-title":"Autophagy protects murine preputial glands against premature aging, and controls their sebum phospholipid and pheromone profile","volume":"18","author":"Rossiter","year":"2022","journal-title":"Autophagy"},{"key":"10.1016\/j.cbi.2024.110905_bib25","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/0031-9384(88)90260-0","article-title":"The role of the preputial glands in sexual attractivity of the female rat","volume":"42","author":"Merkx","year":"1988","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.cbi.2024.110905_bib26","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1177\/00236772211055966","article-title":"Bacteriological and pathological investigations on the preputial glands of one-year-old C57BL\/6NCrl mice maintained in individually ventilated cages","volume":"56","author":"Di Caro","year":"2022","journal-title":"Lab. Anim."},{"key":"10.1016\/j.cbi.2024.110905_bib27","doi-asserted-by":"crossref","first-page":"4623","DOI":"10.1007\/s00018-016-2312-0","article-title":"Genetically modified laboratory mice with sebaceous glands abnormalities","volume":"73","author":"Ehrmann","year":"2016","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.cbi.2024.110905_bib28","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1016\/j.cell.2006.06.048","article-title":"Blimp1 defines a progenitor population that governs cellular input to the sebaceous gland","volume":"126","author":"Horsley","year":"2006","journal-title":"Cell"},{"key":"10.1016\/j.cbi.2024.110905_bib29","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1042\/bj20031300","article-title":"Nucling mediates apoptosis by inhibiting expression of galectin-3 through interference with nuclear factor kappaB signalling","volume":"380","author":"Liu","year":"2004","journal-title":"Biochem. J."}],"container-title":["Chemico-Biological Interactions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0009279724000516?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0009279724000516?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,14]],"date-time":"2025-09-14T14:15:57Z","timestamp":1757859357000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0009279724000516"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4]]},"references-count":29,"alternative-id":["S0009279724000516"],"URL":"https:\/\/doi.org\/10.1016\/j.cbi.2024.110905","relation":{},"ISSN":["0009-2797"],"issn-type":[{"type":"print","value":"0009-2797"}],"subject":[],"published":{"date-parts":[[2024,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"High incidence of sebaceous gland inflammation in aldose reductase-deficient mice","name":"articletitle","label":"Article Title"},{"value":"Chemico-Biological Interactions","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cbi.2024.110905","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"110905"}}