{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T04:55:03Z","timestamp":1790916903636,"version":"4.1.0"},"reference-count":62,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Chemico-Biological Interactions"],"published-print":{"date-parts":[[2024,8]]},"DOI":"10.1016\/j.cbi.2024.111107","type":"journal-article","created":{"date-parts":[[2024,6,10]],"date-time":"2024-06-10T22:51:26Z","timestamp":1718059886000},"page":"111107","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"special_numbering":"C","title":["Targeting IGF2BP1 alleviated benzene hematotoxicity by reprogramming BCAA metabolism and fatty acid oxidation"],"prefix":"10.1016","volume":"398","author":[{"given":"Jingyu","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lin","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ziyan","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiaru","family":"Jing","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ai","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cbi.2024.111107_bib1","doi-asserted-by":"crossref","first-page":"209","DOI":"10.3322\/caac.21660","article-title":"Global cancer statistics 2020: Globocan estimates of incidence and mortality worldwide for 36 cancers in 185 countries","volume":"71","author":"Sung","year":"2021","journal-title":"CA A Cancer J. Clin."},{"key":"10.1016\/j.cbi.2024.111107_bib2","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/S1470-2045(21)00581-7","article-title":"The global burden of adolescent and young adult cancer in 2019: a systematic analysis for the global burden of disease study 2019","volume":"23","author":"Collaborators","year":"2022","journal-title":"Lancet Oncol."},{"key":"10.1016\/j.cbi.2024.111107_bib3","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1016\/S1470-2045(19)30339-0","article-title":"The global burden of childhood and adolescent cancer in 2017: an analysis of the global burden of disease study 2017","volume":"20","author":"Collaborators","year":"2019","journal-title":"Lancet Oncol."},{"key":"10.1016\/j.cbi.2024.111107_bib4","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1002\/ped4.12279","article-title":"Pediatric cancer surveillance in China: a hospital-based introduction","volume":"5","author":"Li","year":"2021","journal-title":"Pediatr Investig"},{"key":"10.1016\/j.cbi.2024.111107_bib5","doi-asserted-by":"crossref","first-page":"n2026","DOI":"10.1136\/bmj.n2026","article-title":"Advances in acute myeloid leukemia","volume":"375","author":"Newell","year":"2021","journal-title":"BMJ"},{"key":"10.1016\/j.cbi.2024.111107_bib6","doi-asserted-by":"crossref","DOI":"10.1289\/EHP4381","article-title":"Association between outdoor air pollution and childhood leukemia: a systematic review and dose-response meta-analysis","volume":"127","author":"Filippini","year":"2019","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.cbi.2024.111107_bib7","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1136\/oemed-2019-105738","article-title":"Parental occupational exposure to benzene and the risk of childhood and adolescent acute lymphoblastic leukaemia: a population-based study","volume":"76","author":"Heck","year":"2019","journal-title":"Occup. Environ. Med."},{"key":"10.1016\/j.cbi.2024.111107_bib8","doi-asserted-by":"crossref","first-page":"1774","DOI":"10.1126\/science.1102443","article-title":"Hematotoxicity in workers exposed to low levels of benzene","volume":"306","author":"Lan","year":"2004","journal-title":"Science"},{"key":"10.1016\/j.cbi.2024.111107_bib9","first-page":"370","article-title":"Epidemiological characteristics of occupational cancers reported - China, 2006-2020","volume":"4","author":"Li","year":"2022","journal-title":"China CDC Wkly"},{"key":"10.1016\/j.cbi.2024.111107_bib10","doi-asserted-by":"crossref","DOI":"10.1111\/ina.13038","article-title":"Health effects of exposure to indoor volatile organic compounds from 1980 to 2017: a systematic review and meta-analysis","volume":"32","author":"Liu","year":"2022","journal-title":"Indoor Air"},{"key":"10.1016\/j.cbi.2024.111107_bib11","article-title":"Global, national, and regional burden of acute myeloid leukemia among 60-89 years-old individuals: insights from a study covering the period 1990 to 2019","volume":"11","author":"Chen","year":"2023","journal-title":"Front. Public Health"},{"key":"10.1016\/j.cbi.2024.111107_bib12","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1038\/s41408-023-00853-3","article-title":"Global burden of hematologic malignancies and evolution patterns over the past 30 years","volume":"13","author":"Zhang","year":"2023","journal-title":"Blood Cancer J."},{"key":"10.1016\/j.cbi.2024.111107_bib13","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1186\/s13045-018-0628-y","article-title":"Insulin-like growth factor 2 mrna-binding protein 1 (igf2bp1) in cancer","volume":"11","author":"Huang","year":"2018","journal-title":"J. Hematol. Oncol."},{"key":"10.1016\/j.cbi.2024.111107_bib14","doi-asserted-by":"crossref","first-page":"2744","DOI":"10.7150\/ijbs.70458","article-title":"The role of insulin-like growth factor 2 mrna-binding proteins (igf2bps) as m(6)a readers in cancer","volume":"18","author":"Sun","year":"2022","journal-title":"Int. J. Biol. Sci."},{"key":"10.1016\/j.cbi.2024.111107_bib15","doi-asserted-by":"crossref","first-page":"48716","DOI":"10.1074\/jbc.M405853200","article-title":"Targeted knockdown of the rna-binding protein crd-bp promotes cell proliferation via an insulin-like growth factor ii-dependent pathway in human k562 leukemia cells","volume":"279","author":"Liao","year":"2004","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.cbi.2024.111107_bib16","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.bcmd.2015.11.006","article-title":"Etv6\/runx1 transcript is a target of rna-binding protein igf2bp1 in t(12;21)(p13;q22)-positive acute lymphoblastic leukemia","volume":"57","author":"Stoskus","year":"2016","journal-title":"Blood Cells Mol. Dis."},{"key":"10.1016\/j.cbi.2024.111107_bib17","doi-asserted-by":"crossref","first-page":"1354","DOI":"10.1038\/s41375-019-0656-9","article-title":"Rna-binding protein igf2bp1 maintains leukemia stem cell properties by regulating hoxb4, myb, and aldh1a1","volume":"34","author":"Elcheva","year":"2020","journal-title":"Leukemia"},{"key":"10.1016\/j.cbi.2024.111107_bib18","doi-asserted-by":"crossref","DOI":"10.1126\/science.aaw5473","article-title":"Metabolic reprogramming and cancer progression","volume":"368","author":"Faubert","year":"2020","journal-title":"Science"},{"key":"10.1016\/j.cbi.2024.111107_bib19","doi-asserted-by":"crossref","DOI":"10.3390\/cancers14215345","article-title":"Metabolic plasticity of cancer stem cells in response to microenvironmental cues","volume":"14","author":"Xie","year":"2022","journal-title":"Cancers"},{"key":"10.1016\/j.cbi.2024.111107_bib20","doi-asserted-by":"crossref","DOI":"10.3390\/ijms22168738","article-title":"Insights on metabolic reprogramming and its therapeutic potential in acute leukemia","volume":"22","author":"Di Martino","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.cbi.2024.111107_bib21","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1186\/s40164-022-00292-z","article-title":"Targeting metabolic reprogramming in chronic lymphocytic leukemia","volume":"11","author":"Nie","year":"2022","journal-title":"Exp. Hematol. Oncol."},{"key":"10.1016\/j.cbi.2024.111107_bib22","doi-asserted-by":"crossref","first-page":"1777","DOI":"10.1016\/j.cmet.2021.07.016","article-title":"The requirement for pyruvate dehydrogenase in leukemogenesis depends on cell lineage","volume":"33","author":"Jun","year":"2021","journal-title":"Cell Metabol."},{"key":"10.1016\/j.cbi.2024.111107_bib23","doi-asserted-by":"crossref","first-page":"1582","DOI":"10.1158\/2159-8290.CD-20-0738","article-title":"Serine biosynthesis is a metabolic vulnerability in flt3-itd-driven acute myeloid leukemia","volume":"11","author":"Bjelosevic","year":"2021","journal-title":"Cancer Discov."},{"key":"10.1016\/j.cbi.2024.111107_bib24","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/bs.ircmb.2022.08.001","article-title":"Targeting amino acid metabolism in cancer","volume":"373","author":"Safrhansova","year":"2022","journal-title":"Int Rev Cell Mol Biol"},{"key":"10.1016\/j.cbi.2024.111107_bib25","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1158\/2159-8290.CD-21-0218","article-title":"Dysregulated lipid synthesis by oncogenic idh1 mutation is a targetable synthetic lethal vulnerability","volume":"13","author":"Thomas","year":"2023","journal-title":"Cancer Discov."},{"key":"10.1016\/j.cbi.2024.111107_bib26","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1038\/nrm3772","article-title":"Metabolic requirements for the maintenance of self-renewing stem cells","volume":"15","author":"Ito","year":"2014","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.cbi.2024.111107_bib27","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.154999","article-title":"Plasma metabolomics study reveals the critical metabolic signatures for benzene-induced hematotoxicity","volume":"7","author":"Guo","year":"2022","journal-title":"JCI Insight"},{"key":"10.1016\/j.cbi.2024.111107_bib28","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1016\/j.ebiom.2019.08.056","article-title":"Benzene metabolites trigger pyroptosis and contribute to haematotoxicity via tet2 directly regulating the aim2\/casp1 pathway","volume":"47","author":"Guo","year":"2019","journal-title":"EBioMedicine"},{"key":"10.1016\/j.cbi.2024.111107_bib29","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2020.111562","article-title":"Association between benzene exposure, serum levels of cytokines and hematological measures in Chinese workers: a cross-sectional study","volume":"207","author":"Wang","year":"2021","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.cbi.2024.111107_bib30","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.leukres.2016.05.009","article-title":"Defining the significance of igf2bp1 overexpression in t(12;21)(p13;q22)-positive leukemia reh cells","volume":"47","author":"Stoskus","year":"2016","journal-title":"Leuk. Res."},{"key":"10.1016\/j.cbi.2024.111107_bib31","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/j.bcmd.2011.02.005","article-title":"Identification of characteristic igf2bp expression patterns in distinct b-all entities","volume":"46","author":"Stoskus","year":"2011","journal-title":"Blood Cells Mol. Dis."},{"key":"10.1016\/j.cbi.2024.111107_bib32","doi-asserted-by":"crossref","first-page":"1895","DOI":"10.1242\/jcs.045278","article-title":"Blocking beta-catenin binding to the zbp1 promoter represses zbp1 expression, leading to increased proliferation and migration of metastatic breast-cancer cells","volume":"122","author":"Gu","year":"2009","journal-title":"J. Cell Sci."},{"key":"10.1016\/j.cbi.2024.111107_bib33","doi-asserted-by":"crossref","first-page":"1478","DOI":"10.1158\/1541-7786.MCR-15-0224","article-title":"Loss of stromal imp1 promotes a tumorigenic microenvironment in the colon","volume":"13","author":"Hamilton","year":"2015","journal-title":"Mol. Cancer Res."},{"key":"10.1016\/j.cbi.2024.111107_bib34","doi-asserted-by":"crossref","first-page":"818","DOI":"10.1016\/j.tranon.2017.07.008","article-title":"A novel imp1 inhibitor, btynb, targets c-myc and inhibits melanoma and ovarian cancer cell proliferation","volume":"10","author":"Mahapatra","year":"2017","journal-title":"Transl Oncol"},{"key":"10.1016\/j.cbi.2024.111107_bib35","doi-asserted-by":"crossref","first-page":"8576","DOI":"10.1093\/nar\/gkaa653","article-title":"The oncofetal rna-binding protein igf2bp1 is a druggable, post-transcriptional super-enhancer of e2f-driven gene expression in cancer","volume":"48","author":"Muller","year":"2020","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.cbi.2024.111107_bib36","doi-asserted-by":"crossref","first-page":"2083","DOI":"10.1182\/blood-2016-09-687822","article-title":"Expression and regulation of c\/ebpalpha in normal myelopoiesis and in malignant transformation","volume":"129","author":"Avellino","year":"2017","journal-title":"Blood"},{"key":"10.1016\/j.cbi.2024.111107_bib37","doi-asserted-by":"crossref","first-page":"2328","DOI":"10.1182\/blood.V89.7.2328","article-title":"Platelet factor 4 and other cxc chemokines support the survival of normal hematopoietic cells and reduce the chemosensitivity of cells to cytotoxic agents","volume":"89","author":"Han","year":"1997","journal-title":"Blood"},{"key":"10.1016\/j.cbi.2024.111107_bib38","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1080\/08977190600988225","article-title":"Roles of platelet factor 4 in hematopoiesis and angiogenesis","volume":"24","author":"Maurer","year":"2006","journal-title":"Growth Factors"},{"key":"10.1016\/j.cbi.2024.111107_bib39","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejphar.2022.174831","article-title":"The contributory roles of the cxcl12\/cxcr4\/cxcr7 axis in normal and malignant hematopoiesis: a possible therapeutic target in hematologic malignancies","volume":"920","author":"Mehrpouri","year":"2022","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.cbi.2024.111107_bib40","doi-asserted-by":"crossref","first-page":"4994","DOI":"10.3390\/ijms15034994","article-title":"Investigation into variation of endogenous metabolites in bone marrow cells and plasma in c3h\/he mice exposed to benzene","volume":"15","author":"Sun","year":"2014","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.cbi.2024.111107_bib41","doi-asserted-by":"crossref","first-page":"1326","DOI":"10.1093\/carcin\/bgab089","article-title":"Metabolome-wide association study of occupational exposure to benzene","volume":"42","author":"Rothman","year":"2021","journal-title":"Carcinogenesis"},{"key":"10.1016\/j.cbi.2024.111107_bib42","doi-asserted-by":"crossref","first-page":"50","DOI":"10.3389\/fonc.2013.00050","article-title":"Newly identified roles of pml in stem cell biology","volume":"3","author":"Ito","year":"2013","journal-title":"Front. Oncol."},{"key":"10.1016\/j.cbi.2024.111107_bib43","doi-asserted-by":"crossref","first-page":"1350","DOI":"10.1038\/nm.2882","article-title":"A pml-ppar-delta pathway for fatty acid oxidation regulates hematopoietic stem cell maintenance","volume":"18","author":"Ito","year":"2012","journal-title":"Nat. Med."},{"key":"10.1016\/j.cbi.2024.111107_bib44","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1186\/s13045-021-01076-4","article-title":"Targeting the metabolic vulnerability of acute myeloid leukemia blasts with a combination of venetoclax and 8-chloro-adenosine","volume":"14","author":"Buettner","year":"2021","journal-title":"J. Hematol. Oncol."},{"key":"10.1016\/j.cbi.2024.111107_bib45","doi-asserted-by":"crossref","DOI":"10.1084\/jem.20200924","article-title":"Mitochondrial metabolism supports resistance to idh mutant inhibitors in acute myeloid leukemia","volume":"218","author":"Stuani","year":"2021","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.cbi.2024.111107_bib46","doi-asserted-by":"crossref","first-page":"2196","DOI":"10.1038\/s41375-022-01635-9","article-title":"Gfi1b acts as a metabolic regulator in hematopoiesis and acute myeloid leukemia","volume":"36","author":"Liu","year":"2022","journal-title":"Leukemia"},{"key":"10.1016\/j.cbi.2024.111107_bib47","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1158\/2159-8290.CD-16-0441","article-title":"Chemotherapy-resistant human acute myeloid leukemia cells are not enriched for leukemic stem cells but require oxidative metabolism","volume":"7","author":"Farge","year":"2017","journal-title":"Cancer Discov."},{"key":"10.1016\/j.cbi.2024.111107_bib48","doi-asserted-by":"crossref","first-page":"e531","DOI":"10.3324\/haematol.2017.175414","article-title":"A reversible carnitine palmitoyltransferase (cpt1) inhibitor offsets the proliferation of chronic lymphocytic leukemia cells","volume":"103","author":"Gugiatti","year":"2018","journal-title":"Haematologica"},{"key":"10.1016\/j.cbi.2024.111107_bib49","doi-asserted-by":"crossref","first-page":"1925","DOI":"10.1182\/blood-2014-12-617498","article-title":"Targeting the leukemia cell metabolism by the cpt1a inhibition: functional preclinical effects in leukemias","volume":"126","author":"Ricciardi","year":"2015","journal-title":"Blood"},{"key":"10.1016\/j.cbi.2024.111107_bib50","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.ebiom.2016.11.025","article-title":"High expression of cpt1a predicts adverse outcomes: a potential therapeutic target for acute myeloid leukemia","volume":"14","author":"Shi","year":"2016","journal-title":"EBioMedicine"},{"key":"10.1016\/j.cbi.2024.111107_bib51","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1186\/s12986-021-00592-x","article-title":"Exogenous l-carnitine ameliorates burn-induced cellular and mitochondrial injury of hepatocytes by restoring cpt1 activity","volume":"18","author":"Li","year":"2021","journal-title":"Nutr. Metab."},{"key":"10.1016\/j.cbi.2024.111107_bib52","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1002\/tox.22939","article-title":"L-carnitine protects against 1,4-benzoquinone-induced apoptosis and DNA damage by suppressing oxidative stress and promoting fatty acid oxidation in k562 cells","volume":"35","author":"Sun","year":"2020","journal-title":"Environ. Toxicol."},{"key":"10.1016\/j.cbi.2024.111107_bib53","doi-asserted-by":"crossref","first-page":"E5896","DOI":"10.1073\/pnas.1801745115","article-title":"Chemoproteomics reveals baicalin activates hepatic cpt1 to ameliorate diet-induced obesity and hepatic steatosis","volume":"115","author":"Dai","year":"2018","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.cbi.2024.111107_bib54","doi-asserted-by":"crossref","first-page":"1405","DOI":"10.1172\/JCI89452","article-title":"Amino acid-insensitive mtorc1 regulation enables nutritional stress resilience in hematopoietic stem cells","volume":"127","author":"Kalaitzidis","year":"2017","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.cbi.2024.111107_bib55","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.exphem.2018.04.004","article-title":"Branched-chain amino acid depletion conditions bone marrow for hematopoietic stem cell transplantation avoiding amino acid imbalance-associated toxicity","volume":"63","author":"Wilkinson","year":"2018","journal-title":"Exp. Hematol."},{"key":"10.1016\/j.cbi.2024.111107_bib56","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1097\/MCO.0000000000000430","article-title":"Branched-chain amino acid metabolism in cancer","volume":"21","author":"Ananieva","year":"2018","journal-title":"Curr. Opin. Clin. Nutr. Metab. Care"},{"key":"10.1016\/j.cbi.2024.111107_bib57","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1038\/nature24294","article-title":"Bcat1 restricts alphakg levels in aml stem cells leading to idhmut-like DNA hypermethylation","volume":"551","author":"Raffel","year":"2017","journal-title":"Nature"},{"key":"10.1016\/j.cbi.2024.111107_bib58","doi-asserted-by":"crossref","first-page":"1228","DOI":"10.1158\/2159-8290.CD-19-0152","article-title":"Loss of ezh2 reprograms bcaa metabolism to drive leukemic transformation","volume":"9","author":"Gu","year":"2019","journal-title":"Cancer Discov."},{"key":"10.1016\/j.cbi.2024.111107_bib59","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1038\/nature22314","article-title":"Cancer progression by reprogrammed bcaa metabolism in myeloid leukaemia","volume":"545","author":"Hattori","year":"2017","journal-title":"Nature"},{"key":"10.1016\/j.cbi.2024.111107_bib60","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1038\/s41419-021-03456-7","article-title":"Bcat1 decreases the sensitivity of cancer cells to cisplatin by regulating mtor-mediated autophagy via branched-chain amino acid metabolism","volume":"12","author":"Luo","year":"2021","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.cbi.2024.111107_bib61","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1038\/nchembio.1961","article-title":"Branched-chain amino acid catabolism fuels adipocyte differentiation and lipogenesis","volume":"12","author":"Green","year":"2016","journal-title":"Nat. Chem. Biol."},{"key":"10.1016\/j.cbi.2024.111107_bib62","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1093\/nar\/30.1.207","article-title":"Gene expression omnibus: ncbi gene expression and hybridization array data repository","volume":"30","author":"Edgar","year":"2002","journal-title":"Nucleic Acids Res."}],"container-title":["Chemico-Biological Interactions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0009279724002539?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0009279724002539?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,9,26]],"date-time":"2024-09-26T12:38:33Z","timestamp":1727354313000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0009279724002539"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8]]},"references-count":62,"alternative-id":["S0009279724002539"],"URL":"https:\/\/doi.org\/10.1016\/j.cbi.2024.111107","relation":{},"ISSN":["0009-2797"],"issn-type":[{"value":"0009-2797","type":"print"}],"subject":[],"published":{"date-parts":[[2024,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Targeting IGF2BP1 alleviated benzene hematotoxicity by reprogramming BCAA metabolism and fatty acid oxidation","name":"articletitle","label":"Article Title"},{"value":"Chemico-Biological Interactions","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cbi.2024.111107","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"111107"}}